UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

SCHEDULE 13D

Under the Securities Exchange Act of 1934

(Amendment No. 1)

GenVec, Inc.

(Name of Issuer)

Common Stock, par value $.001 per share

(Title of Class of Securities)

37246C109

(CUSIP Number)

Anthony Chrampanis

Landesbank Berlin AG

Alexanderplatz 2

D-10178 Berlin

Germany

+49 30 2456 1239

(Name, Address and Telephone Number of Person Authorized to

Receive Notices and Communications)

August 8, 2007

(Date of Event which Requires Filing of this Statement)

If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§240.13d-l(e), 240.13d-l(f) or 240.13d-l(g), check the following box. o

CUSIP No. [ 37246C109 ]

Names of Reporting Persons.

I.R.S. Identification Nos. of above persons (entities only).

Landesbank Berlin AG

IRS No.

Check the Appropriate Box if a Member of a Group (See Instructions)

(a)

(b)

	3.	SEC Use Only

Source of funds (See Instructions)

5. Check Box if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e) o

Citizenship or Place of Organization

Federal Republic of Germany

Number of

Sole Voting Power: 5,220,000

Shares Bene-

ficially

Shared Voting Power:

Owned by Each

Reporting

Sole Dispositive Power: 5,220,000

Person with:

10.

Shared Dispositive Power:

11.

Aggregate Amount Beneficially Owned by Each Reporting Person

5,220,000

12. Check Box if the Aggregate Amount in Row (11) Excludes Certain Shares (See Instructions)

13.

Percent of Class Represented by Amount in Row (11)

6.9%

14.

Type of Reporting Person (See Instructions)

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This Amendment No. 1 amends and supplements items 2, 3, 4 and 5 of the Statement on Schedule 13D (the “Previous Schedule 13D”) of Landesbank Berlin AG (“LB”), a wholly owned subsidiary of Landesbank Berlin Holding AG (the "Parent"), which is in turn controlled by Erwerbsgesellschaft der S-Finanzgruppe mbH & Co. KG, a German limited partnership (the “Partnership”), with respect to the shares of Common Stock, par value $.001 per share (the "Common Stock"), of GenVec, Inc. (the “Company"). Statements by LB and the Parent in the Previous Schedule 13D that are not modified in this amendment are not amended and remain as previously reported.

Item 2. Identity and Background

The general partner of the Partnership is Regionalverbandsgesellschaft mbH, a German limited liability company (“RVG”) owned by several German regional savings bank associations. The principal offices of both the Partnership and RVG are located at Charlottenstrasse 47, D-10117 Berlin, Federal Republic of Germany. Annex C hereto sets forth the name, address and principal occupation of each of the Executive Directors of RVG. Based on the information about such Executive Directors that is available to the Parent and LB pursuant to German law, neither the Parent nor LB is aware of any information to the effect that any such person has during the last five years been a party to any criminal or civil proceeding. All of the individuals listed on Annex C are citizens of the Federal Republic of Germany.

The amendment to Annex A attached hereto sets forth the name, address and principal occupation of each director and executive officer of LB. Based on the information about the persons listed on Annex A that is available to the Parent and LB pursuant to German labor law (including a police certificate of no criminal record), neither the Parent nor LB is aware of any information to the effect that any such person has during the last five years been party to any criminal or civil proceeding. All of the individuals listed on Annex A are citizens of the Federal Republic of Germany.

Item 3. Source and Amount of Funds or Other Consideration

The source of the funds used by LB to purchase the shares of Common Stock reported as held by LB in Item 5 of this Statement on Schedule 13D was working capital, and LB anticipates that its source of funds to purchase any further shares of Common Stock will also be working capital.

Item 4. Purpose of Transaction

Item 4 of the Previous Schedule 13D is hereby amended in its entirety to read as follows:

On August 8, 2007, the Partnership acquired approximately 81% of the common voting stock of the Parent from the Land Berlin (the State of Berlin) and became the controlling person of the Parent and LB.

The shares of Common Stock held by LB were acquired for the purpose of investment. Depending upon the Company's business and prospects, and upon future developments, LB may from time to time purchase additional shares of Common Stock, dispose of all or a portion of the shares of Common Stock that LB holds or cease buying or selling shares of Common Stock. Factors that may influence LB’s decision to purchase additional shares or to sell all or a portion of its holdings include, but are not limited to, the performance of the shares of Common Stock in the market, the Company’s economic performance and prospects, LB’s assessment of decisions by the Company’s Board of Directors concerning the Company’s capital structure and business strategies, the availability of funds, alternative uses of funds, stock and money market conditions and general economic conditions. Any additional purchases or sales of the shares of Common Stock may be in the open market, in privately negotiated transactions or otherwise.

LB has not formulated any plans or proposals that relate to or would result in the kind of transactions specified in items 4(a) through (j) of Schedule 13D. LB will review its investment in the Company from time to time and reserves the right to take or not take any action it deems to be in its best interest or to change its intentions as set forth in this Item 4.

Item 5. Interest in Securities of the Issuer

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According to the Company’s filing on Form 10-Q made on August 9, 2007, as of July 31, 2007 there were 75,365,992 shares of Common Stock outstanding. The percentage set forth in this Item 5 is derived using such number.

(a) LB owns 5,220,000 shares of the Common Stock, representing approximately 6.9% of the outstanding shares of Common Stock

(b) LB has sole power to vote and to dispose of the shares of Common Stock owned by it.

(c) LB has not engaged in any transactions in the Common Stock in the last 60 days, nor did it engage in any transactions in the Common Stock during the 60 days preceding August 8, 2007.

(d) and (e) Inapplicable.

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Signature

After reasonable inquiry and to the best of the undersigned’s knowledge and belief, the undersigned certify that the information set forth in this statement is true, complete and correct.

Date: September 12, 2007

LANDESBANK BERLIN AG

By: /s/ Dirk Kipp

Name: Dirk Kipp

Title:

Managing Director

By: /s/ Anthony Chrampanis

Name: Anthony Chrampanis

Title:

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Annex A

Unless otherwise indicated, the business address for all individuals listed in this Annex A is Landesbank Berlin AG, Alexanderplatz 2, D-10178 Berlin, Federal Republic of Germany.

Landesbank Berlin AG

Members of the Managing Board

Name and Address	Principal Occupation
Hans-Jörg Vetter	Chairman of the Managing Board of Landesbank Berlin AG
Serge Demolière	Member of the Managing Board of Landesbank Berlin AG
Dr. Johannes Evers	Member of the Managing Board of Landesbank Berlin AG
Hans Jürgen Kulartz	Member of the Managing Board of Landesbank Berlin AG
Martin Klaus Müller	Member of the Managing Board of Landesbank Berlin AG
Dr. Thomas Veit	Member of the Managing Board of Landesbank Berlin AG

Executive Officers

Name and Address	Principal Occupation
Alt, Volker Landesbank Berlin AG Recht Alexanderplatz 2 D-10178 Berlin	Managing Director of Landesbank Berlin AG
Berentin, Ronald Landesbank Berlin AG Berliner Sparkasse Kredit Firmenkunden und Privatkunden Brunnenstraße 111 D-13355 Berlin	Managing Director of Landesbank Berlin AG

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Name and Address	Principal Occupation
Boenke, Frank-Michael Landesbank Berlin AG Compliance Brunnenstraße 111 D-13355 Berlin	Managing Director of Landesbank Berlin AG
Brummel, Beate Landesbank Berlin AG Kreditbereich Kapitalmarkt Strukturierte Finanzierungen/Projektfinanzierungen Alexanderplatz 2 D-10178 Berlin	Managing Director of Landesbank Berlin AG
Burmester, Dr. Christian Landesbank Berlin AG London Branch 1 Crown Court Cheapside GB-London EC2V 6LR	General Manager of Landesbank Berlin AG London Branch
Butzer, Arnold Landesbank Berlin AG Vertrieb Immobilienfinanzierung Berlin und Neue Bundesländer Corneliusstr, 7 D-10787 Berlin	Managing Director of Landesbank Berlin AG
Gottschalk, Gudrun Landesbank Berlin AG Datenschutz und Geldwäsche Brunnenstr. 111 D-13355 Berlin	Managing Director of Landesbank Berlin AG
Hirschhaeuser, Dr. Karl-Friedrich Landesbank Berlin AG Risikocontrolling Brunnenstraße 111 D-13355 Berlin	Managing Director of Landesbank Berlin AG
Jänichen, Michael Landesbank Berlin AG Berliner Sparkasse Firmenkunden Badensche Str. 23 D-10715 Berlin	Managing Director of Landesbank Berlin AG

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Name and Address	Principal Occupation
Jordan, Axel Landesbank Berlin AG Kredit Immobilien Corneliusstraße 7 D-10787 Berlin	Managing Director of Landesbank Berlin AG
Kipp, Dirk Landesbank Berlin AG Treasury & Trading Alexanderplatz 2 D-10178 Berlin	Managing Director of Landesbank Berlin AG
Lange, Axel Landesbank Berlin AG Kreditbereich IBAG/IBG Hardenbergstr. 20 D-10623 Berlin	Managing Director of Landesbank Berlin AG
Papesch, Uwe Landesbank Berlin AG Client Business Alexanderplatz 2 D-10178 Berlin	Managing Director of Landesbank Berlin AG
Pritzsche, Wolfgang Landesbank Berlin AG Finanzen Brunnenstraße 111 D-13355 Berlin	Managing Director of Landesbank Berlin AG
Reutter, Dr. Georg Landesbank Berlin AG Vertrieb Immobilienfinanzierung Alte Bundesländer Corneliusstr, 7 D-10787 Berlin	Managing Director of Landesbank Berlin AG
Richardt, Claus-Günther Landesbank Berlin AG Berliner Sparkasse Vermögensanlagen Badensche Str. 23 D-10715 Berlin	Managing Director of Landesbank Berlin AG
Roller, Gerhard Landesbank Berlin AG Internationales Geschäft Alexanderplatz 2 D-10178 Berlin-	Managing Director of Landesbank Berlin AG

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Name and Address	Principal Occupation
Scheer, Heinz-Günter Landesbank Berlin AG Unternehmensentwicklung Alexanderplatz 2 D-10178 Berlin	Managing Director of Landesbank Berlin AG
Schölper, Siegfried Landesbank Berlin AG Controlling Alexanderplatz 2 D-10178 Berlin	Managing Director of Landesbank Berlin AG
Schroeder, Bartho Landesbank Berlin AG Business Management Alexanderplatz 2 D-10178 Berlin	Managing Director of Landesbank Berlin AG
Thanheiser, Michael Landesbank Berlin AG Berliner Sparkasse Privatkunden Badensche Str. 23 D-10715 Berlin	Managing Director of Landesbank Berlin AG

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Annex C

Regionalverbandsgesellschaft mbH

Executive Directors

Unless otherwise indicated, the business address for all individuals listed in this Annex C is Regionalverbandsgesellschaft mbH, Charlottenstrasse 47, D-10117 Berlin, Federal Republic of Germany.

Name and Address	Principal Occupation
Dr. Karl-Peter Schackmann-Fallis	Executive Member of the Board of the Deutscher Sparkassen- und Giroverbandes e.V. (German savings bank association) (“DSGVeV”)
Carsten Steffan	Department Head at DSGVeV
Heinrich Haasis	President of DSGVeV

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