0001172661-20-001263.txt : 20200515 0001172661-20-001263.hdr.sgml : 20200515 20200515094106 ACCESSION NUMBER: 0001172661-20-001263 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20200331 FILED AS OF DATE: 20200515 DATE AS OF CHANGE: 20200515 EFFECTIVENESS DATE: 20200515 FILER: COMPANY DATA: COMPANY CONFORMED NAME: GILDER GAGNON HOWE & CO LLC CENTRAL INDEX KEY: 0000902464 IRS NUMBER: 133174112 STATE OF INCORPORATION: NY FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-03455 FILM NUMBER: 20881306 BUSINESS ADDRESS: STREET 1: 475 10TH AVENUE CITY: NEW YORK STATE: NY ZIP: 10018 BUSINESS PHONE: 2127652500 MAIL ADDRESS: STREET 1: 475 10TH AVENUE CITY: NEW YORK STATE: NY ZIP: 10018 FORMER COMPANY: FORMER CONFORMED NAME: GILDER GAGNON HOWE & CO DATE OF NAME CHANGE: 19930428 13F-HR 1 primary_doc.xml 13F-HR LIVE false true false 0000902464 XXXXXXXX 03-31-2020 03-31-2020 false GILDER GAGNON HOWE & CO LLC

475 10th Avenue New York NY 10018

13F HOLDINGS REPORT 028-03455 N Laura Esposito 212-424-0226 /s/ Laura Esposito New York NY 05-15-2020 0 292 8341031 INFORMATION TABLE 2 infotable.xml 1LIFE HEALTHCARE INC COM 68269G107 28798 1586652 SH DFND 0 0 1586652 2U INC COM 90214J101 687 32379 SH DFND 0 0 32379 ABIOMED INC COM 003654100 19993 137731 SH DFND 0 0 137731 ACACIA COMMUNICATIONS INC COM 00401C108 575 8565 SH DFND 0 0 8565 ACCEL ENTERTAINMENT INC COM CL A1 00436Q106 18 2400 SH DFND 0 0 2400 ACTIVISION BLIZZARD INC COM 00507V109 1210 20342 SH DFND 0 0 20342 ADAPTIVE BIOTECHNOLOGIES COR COM 00650F109 63318 2279250 SH DFND 0 0 2279250 ADESTO TECHNOLOGIES CORP COM 00687D101 10987 981830 SH DFND 0 0 981830 ADOBE INC COM 00724F101 45868 144130 SH DFND 0 0 144130 ADYEN NV 144A COM N3501V104 29293 34644 SH DFND 0 0 34644 AEROJET ROCKETDYNE HLDGS INC COM 007800105 40853 976651 SH DFND 0 0 976651 AFYA LTD CL A COM G01125106 6455 338662 SH DFND 0 0 338662 ALASKA COMMUNICATIONS SYS GR COM 01167P101 1927 1107622 SH DFND 0 0 1107622 ALECTOR INC COM 014442107 65788 2726389 SH DFND 0 0 2726389 ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 75018 385734 SH DFND 0 0 385734 ALLAKOS INC COM 01671P100 3371 75759 SH DFND 0 0 75759 ALLEGIANT TRAVEL CO COM 01748X102 7240 88509 SH DFND 0 0 88509 ALNYLAM PHARMACEUTICALS INC COM 02043Q107 100052 919177 SH DFND 0 0 919177 ALPHABET INC CAP STK CL A 02079K305 50156 43165 SH DFND 0 0 43165 ALPHABET INC CAP STK CL C 02079K107 55816 48001 SH DFND 0 0 48001 ALTERYX INC COM CL A 02156B103 3431 36047 SH DFND 0 0 36047 ALTUS MIDSTREAM CO CL A 02215L100 1193 1591184 SH DFND 0 0 1591184 AMAZON COM INC COM 023135106 343261 176057 SH DFND 0 0 176057 AMERICAN TOWER CORP NEW COM 03027X100 17253 79231 SH DFND 0 0 79231 AMERICOLD RLTY TR COM 03064D108 1369 40228 SH DFND 0 0 40228 AMYRIS INC COM NEW 03236M200 130 50718 SH DFND 0 0 50718 ANAPLAN INC COM 03272L108 5614 185531 SH DFND 0 0 185531 ANTERIX INC COM 03676C100 272 5953 SH DFND 0 0 5953 APACHE CORP COM 037411105 1062 254101 SH DFND 0 0 254101 APPFOLIO INC COM CL A 03783C100 53067 478301 SH DFND 0 0 478301 APPIAN CORP CL A 03782L101 1641 40787 SH DFND 0 0 40787 APPLE INC COM 037833100 6971 27415 SH DFND 0 0 27415 APPLIED OPTOELECTRONICS INC COM 03823U102 54 7050 SH DFND 0 0 7050 APTOSE BIOSCIENCES INC COM NEW 03835T200 1 125 SH DFND 0 0 125 ARCO PLATFORM LTD COM CL A G04553106 12 285 SH DFND 0 0 285 ARCUS BIOSCIENCES INC COM 03969F109 279 20130 SH DFND 0 0 20130 ARGENX SE SPONSORED ADR 04016X101 819 6215 SH DFND 0 0 6215 ARISTA NETWORKS INC COM 040413106 81504 402388 SH DFND 0 0 402388 ARITZIA INC SUB VTG SHS ISIN CA04045U1021 SEDOL BDCG2C2 COM 04045U102 11834 1368259 SH DFND 0 0 1368259 ARVINAS INC COM 04335A105 63524 1576272 SH DFND 0 0 1576272 ATLASSIAN CORP PLC CL A G06242104 26945 196305 SH DFND 0 0 196305 AUTO TRADER GROUP PLC ORD GBP001 ISIN GB00BVYVFW23 SEDOL BVYV COM G06708104 1785 327783 SH DFND 0 0 327783 AUTODESK INC COM 052769106 92984 595670 SH DFND 0 0 595670 AXIS BANK GDR EACH REPR 1 INR10 REG S ISIN US05462W1099 SEDOL COM 05462W109 382 15085 SH DFND 0 0 15085 AXOGEN INC COM 05463X106 280 26940 SH DFND 0 0 26940 AZUL S A SPONSR ADR PFD 05501U106 33802 3317193 SH DFND 0 0 3317193 BASICFIT NV 144A REG S ISIN NL0011872650 SEDOL BD9Y9B7 COM N10058100 7 427 SH DFND 0 0 427 BEAM THERAPEUTICS INC COM 07373V105 1617 89813 SH DFND 0 0 89813 BENEFYTT TECHNOLOGIES INC COM CL A 08182C106 291 13010 SH DFND 0 0 13010 BERKLEY W R CORP COM 084423102 4448 85261 SH DFND 0 0 85261 BERKSHIRE HATHAWAY INC DEL CL B NEW 084670702 501 2739 SH DFND 0 0 2739 BEYOND MEAT INC COM 08862E109 26333 395388 SH DFND 0 0 395388 BIOHAVEN PHARMACTL HLDG CO L COM G11196105 3476 102159 SH DFND 0 0 102159 BK OF AMERICA CORP COM 060505104 1 35 SH DFND 0 0 35 BLUEBIRD BIO INC COM 09609G100 25432 553361 SH DFND 0 0 553361 BOSTON SCIENTIFIC CORP COM 101137107 751 23029 SH DFND 0 0 23029 CALIX INC COM 13100M509 11252 1589330 SH DFND 0 0 1589330 CARL ZEISS MEDITEC AG NPV ISIN DE0005313704 SEDOL 5922961 COM D14895102 1186 12231 SH DFND 0 0 12231 CARVANA CO CL A 146869102 48306 876850 SH DFND 0 0 876850 CASPER SLEEP INC COM 147626105 52 12047 SH DFND 0 0 12047 CATAPULT GROUP INTERNATIONAL ISIN AU000000CAT9 SEDOL BTL0Y76 COM Q2159P101 86 186848 SH DFND 0 0 186848 CELLNEX TELECOM SAU EUR025 144A REG S ISIN ES0105066007 SEDOL COM E2R41M104 5711 125577 SH DFND 0 0 125577 CHART INDS INC COM PAR $0.01 16115Q308 25 860 SH DFND 0 0 860 CHEGG INC COM 163092109 60022 1677542 SH DFND 0 0 1677542 CHEWY INC CL A 16679L109 448 11937 SH DFND 0 0 11937 CHIPOTLE MEXICAN GRILL INC COM 169656105 1 1 SH DFND 0 0 1 CITIGROUP INC COM NEW 172967424 1 35 SH DFND 0 0 35 CLOUDFLARE INC CL A COM 18915M107 86198 3671111 SH DFND 0 0 3671111 CODEXIS INC COM 192005106 30787 2758707 SH DFND 0 0 2758707 COLLATERAL DELV TO BANK OF AMERICA NA SECURITIES ON LOAN NOT COV COM L0C990089 0 907358 SH DFND 0 0 907358 CONTROLADORA VUELA CIA DE AV SPON ADR RP 10 21240E105 9596 2797775 SH DFND 0 0 2797775 CORECIVIC INC COM 21871N101 90 8079 SH DFND 0 0 8079 COUPA SOFTWARE INC COM 22266L106 20967 150057 SH DFND 0 0 150057 COVANTA HLDG CORP COM 22282E102 5952 696141 SH DFND 0 0 696141 COVETRUS INC COM 22304C100 0 8 SH DFND 0 0 8 CRIMSON WINE GROUP COM USD001 COM 22662X100 530 90678 SH DFND 0 0 90678 CROWDSTRIKE HLDGS INC CL A 22788C105 13991 251269 SH DFND 0 0 251269 DATADOG INC CL A COM 23804L103 15960 443591 SH DFND 0 0 443591 DENALI THERAPEUTICS INC COM 24823R105 57100 3261022 SH DFND 0 0 3261022 DEXCOM INC COM 252131107 158545 588796 SH DFND 0 0 588796 DIAMOND EAGLE ACQUISITION CO COM CL A 25258L109 13 1080 SH DFND 0 0 1080 DIAMONDBACK ENERGY INC COM 25278X109 549 20959 SH DFND 0 0 20959 DIGI INTL INC COM 253798102 623 65332 SH DFND 0 0 65332 DINE BRANDS GLOBAL INC COM 254423106 667 23270 SH DFND 0 0 23270 DISH NETWORK CORPORATION CL A 25470M109 25648 1283036 SH DFND 0 0 1283036 DISNEY WALT CO COM DISNEY 254687106 3459 35808 SH DFND 0 0 35808 DOCUSIGN INC COM 256163106 135159 1462756 SH DFND 0 0 1462756 DOWNEY FINL CORP COM 261018105 0 200 SH DFND 0 0 200 EHEALTH INC COM 28238P109 36844 261636 SH DFND 0 0 261636 EIDOS THERAPEUTICS INC COM 28249H104 17540 358034 SH DFND 0 0 358034 ELASTIC N V ORD SHS N14506104 2804 50249 SH DFND 0 0 50249 ENPHASE ENERGY INC COM 29355A107 86608 2682194 SH DFND 0 0 2682194 ENTERCOM COMMUNICATIONS CORP CL A 293639100 314 183734 SH DFND 0 0 183734 EPAM SYS INC COM 29414B104 72717 391668 SH DFND 0 0 391668 EQUATOR EXPLORATION COM STK NPV COM G3084F128 0 215000 SH DFND 0 0 215000 EROS INTL PLC SHS NEW G3788M114 68 41348 SH DFND 0 0 41348 ESPERION THERAPEUTICS INC NE COM 29664W105 36 1128 SH DFND 0 0 1128 ETSY INC COM 29786A106 19741 513549 SH DFND 0 0 513549 EXACT SCIENCES CORP COM 30063P105 90598 1562036 SH DFND 0 0 1562036 FACEBOOK INC CL A 30303M102 62704 375921 SH DFND 0 0 375921 FASTLY INC CL A 31188V100 11498 605815 SH DFND 0 0 605815 FERGUSON PLC ORD GBP010 ISIN JE00BJVNSS43 SEDOL BJVNSS4 COM G3421J106 8131 129693 SH DFND 0 0 129693 FIVE BELOW INC COM 33829M101 43978 624869 SH DFND 0 0 624869 FLEX LNG LTD BM USD010 ISIN BMG359472021 SEDOL BJJMGB2 COM ZZCKKNHC2 675 133455 SH DFND 0 0 133455 FLEXION THERAPEUTICS INC COM 33938J106 219 27832 SH DFND 0 0 27832 FLOOR & DECOR HLDGS INC CL A 339750101 3391 105681 SH DFND 0 0 105681 FORESCOUT TECHNOLOGIES INC COM 34553D101 1293 40927 SH DFND 0 0 40927 FOUR SEAS MERCANTILE HLDGS HKD010 ISIN KYG365451049 SEDOL 634 COM G36545104 101 270000 SH DFND 0 0 270000 FRANCO NEVADA CORP COM 351858105 7326 73616 SH DFND 0 0 73616 FRESHPET INC COM 358039105 144687 2265343 SH DFND 0 0 2265343 FRIENDLY ENERGY EXPLORATION COM NPV COM 35846A200 0 690 SH DFND 0 0 690 GALAPAGOS NV NPV ISIN BE0003818359 SEDOL B07Q2V5 COM B44170106 129714 653136 SH DFND 0 0 653136 GASLOG LTD SHS G37585109 37 10265 SH DFND 0 0 10265 GEOPARK LTD USD SHS G38327105 2994 423481 SH DFND 0 0 423481 GILEAD SCIENCES INC COM 375558103 2073 27729 SH DFND 0 0 27729 GLAUKOS CORP COM 377322102 28836 934413 SH DFND 0 0 934413 GLOBAL BLOOD THERAPEUTICS IN COM 37890U108 1 13 SH DFND 0 0 13 GLOBANT S A COM L44385109 63801 725996 SH DFND 0 0 725996 GOLAR LNG LTD SHS G9456A100 74 9393 SH DFND 0 0 9393 GOLDEN MINERALS CO COM 381119106 10 47017 SH DFND 0 0 47017 GOLDMAN SACHS GROUP INC COM 38141G104 64080 414517 SH DFND 0 0 414517 GRID DYNAMICS HLDGS INC COM CL A 39813G109 202 25246 SH DFND 0 0 25246 GROCERY OUTLET HLDG CORP COM 39874R101 3421 99627 SH DFND 0 0 99627 GTT COMMUNICATIONS INC COM 362393100 10132 1274521 SH DFND 0 0 1274521 GUARDANT HEALTH INC COM 40131M109 714 10253 SH DFND 0 0 10253 HDFC BANK LTD SPONSORED ADS 40415F101 5616 146034 SH DFND 0 0 146034 HEALTHEQUITY INC COM 42226A107 3308 65393 SH DFND 0 0 65393 HEARUSA INC NEW COM 422360305 0 375 SH DFND 0 0 375 HEICO CORP NEW CL A 422806208 3757 58795 SH DFND 0 0 58795 HELLOFRESH SE SHS ISIN DE000A161408 SEDOL BYWH8S0 COM D3R2MA100 54262 1616098 SH DFND 0 0 1616098 HOWARD HUGHES CORP COM 44267D107 186 3686 SH DFND 0 0 3686 HUBSPOT INC COM 443573100 89180 669571 SH DFND 0 0 669571 ICICI BANK LIMITED ADR 45104G104 3011 354195 SH DFND 0 0 354195 ILLUMINA INC COM 452327109 4863 17807 SH DFND 0 0 17807 IMPINJ INC COM 453204109 798 47732 SH DFND 0 0 47732 INPHI CORP COM 45772F107 710 8967 SH DFND 0 0 8967 INSPIRE MED SYS INC COM 457730109 56173 931871 SH DFND 0 0 931871 INSULET CORP COM 45784P101 3031 18296 SH DFND 0 0 18296 INTERBREW PLC GDR EACH REPR 1 A SHS SPON REG SEUR COM 45845T308 0 200 SH DFND 0 0 200 INTL GNRL INSURANCE HLDNGS L SHS G4809J106 17492 2186440 SH DFND 0 0 2186440 INTUITIVE SURGICAL INC COM NEW 46120E602 92241 186266 SH DFND 0 0 186266 INVITAE CORP COM 46185L103 86261 6310263 SH DFND 0 0 6310263 IRHYTHM TECHNOLOGIES INC COM 450056106 28300 347876 SH DFND 0 0 347876 JPMORGAN CHASE & CO COM 46625H100 1528 16974 SH DFND 0 0 16974 KAMBI GROUP PLC EUR0003 ISIN MT0000780107 SEDOL BMNQDC1 COM X4170A107 10 1097 SH DFND 0 0 1097 KB HOME COM 48666K109 153 8437 SH DFND 0 0 8437 KIRKLAND LAKE GOLD LTD COM 49741E100 11330 382767 SH DFND 0 0 382767 KORNIT DIGITAL LTD SHS M6372Q113 24206 972505 SH DFND 0 0 972505 KRYSTAL BIOTECH INC COM 501147102 2 37 SH DFND 0 0 37 KURA SUSHI USA INC CL A COM 501270102 638 53377 SH DFND 0 0 53377 LGI HOMES INC COM 50187T106 58692 1299944 SH DFND 0 0 1299944 LHC GROUP INC COM 50187A107 2354 16787 SH DFND 0 0 16787 LI NING CO LTD HKD01 ISIN KYG5496K1242 SEDOL B01JCK9 COM G5496K124 13 4391 SH DFND 0 0 4391 LIBERTY MEDIA CORP DEL COM A BRAVES GRP 531229706 2788 142956 SH DFND 0 0 142956 LIBERTY MEDIA CORP DEL COM C BRAVES GRP 531229888 7482 392547 SH DFND 0 0 392547 LIBERTY MEDIA CORP DEL COM SER C FRMLA 531229854 1032 37901 SH DFND 0 0 37901 LIVE NATION ENTERTAINMENT IN COM 538034109 303 6655 SH DFND 0 0 6655 LIVEPERSON INC COM 538146101 26035 1144399 SH DFND 0 0 1144399 LIVONGO HEALTH INC COM 539183103 25476 892968 SH DFND 0 0 892968 LOVESAC COMPANY COM 54738L109 166 28461 SH DFND 0 0 28461 LUCKIN COFFEE INC SPONSORED ADS 54951L109 14414 530131 SH DFND 0 0 530131 LULULEMON ATHLETICA INC COM 550021109 6539 34497 SH DFND 0 0 34497 LUMENTUM HLDGS INC COM 55024U109 732 9931 SH DFND 0 0 9931 LYFT INC CL A COM 55087P104 27225 1013957 SH DFND 0 0 1013957 MAG SILVER CORP COM 55903Q104 10775 1402981 SH DFND 0 0 1402981 MAGENTA THERAPEUTICS INC COM 55910K108 25495 4059789 SH DFND 0 0 4059789 MAGNOLIA OIL & GAS CORP CL A 559663109 2574 643556 SH DFND 0 0 643556 MARTIN MARIETTA MATLS INC COM 573284106 71395 377294 SH DFND 0 0 377294 MASTERCARD INC CL A 57636Q104 20344 84219 SH DFND 0 0 84219 MATCH GROUP INC COM 57665R106 62064 939788 SH DFND 0 0 939788 MAYVILLE ENGINEERING CO INC COM 578605107 757 123482 SH DFND 0 0 123482 MERCADOLIBRE INC COM 58733R102 75565 154663 SH DFND 0 0 154663 MICRON TECHNOLOGY INC COM 595112103 638 15166 SH DFND 0 0 15166 MICROSOFT CORP COM 594918104 42572 269937 SH DFND 0 0 269937 MOLECULAR TEMPLATES INC COM 608550109 9577 720582 SH DFND 0 0 720582 MONGODB INC CL A 60937P106 124416 911205 SH DFND 0 0 911205 MONOLITHIC PWR SYS INC COM 609839105 15756 94087 SH DFND 0 0 94087 NATERA INC COM 632307104 34114 1142453 SH DFND 0 0 1142453 NATIONAL VISION HLDGS INC COM 63845R107 11 587 SH DFND 0 0 587 NEOPHOTONICS CORP COM 64051T100 949 130913 SH DFND 0 0 130913 NETFLIX INC COM 64110L106 473221 1260242 SH DFND 0 0 1260242 NEW PACIFIC METALS CORP COM NPV ISIN CA6478241012 SEDOL BF4CP8 COM 647824101 4912 1412324 SH DFND 0 0 1412324 NEW YORK TIMES CO CL A 650111107 92148 3000594 SH DFND 0 0 3000594 NIKE INC CL B 654106103 9851 119059 SH DFND 0 0 119059 NOBLE MIDSTREAM PARTNERS LP COM UNIT REPST 65506L105 3 947 SH DFND 0 0 947 NV5 GLOBAL INC COM 62945V109 27 644 SH DFND 0 0 644 NVIDIA CORP COM 67066G104 46670 177047 SH DFND 0 0 177047 OCADO GROUP PLC ORD GBP002 ISIN GB00B3MBS747 SEDOL B3MBS74 COM G6718L106 175387 11594000 SH DFND 0 0 11594000 OKTA INC CL A 679295105 210596 1722526 SH DFND 0 0 1722526 ONEWATER MARINE INC CL A COM 68280L101 4864 635823 SH DFND 0 0 635823 OPTION CARE HEALTH INC COM NEW 68404L201 35553 3754279 SH DFND 0 0 3754279 PAGERDUTY INC COM 69553P100 895 51783 SH DFND 0 0 51783 PALOMAR HLDGS INC COM 69753M105 11909 204761 SH DFND 0 0 204761 PARAMOUNT RESOURCES LIMITED COM NPV CLASS A ISIN CA6993202069 S COM 699320206 118 148418 SH DFND 0 0 148418 PAYPAL HLDGS INC COM 70450Y103 10525 109935 SH DFND 0 0 109935 PDF SOLUTIONS INC COM 693282105 322 27448 SH DFND 0 0 27448 PELOTON INTERACTIVE INC CL A COM 70614W100 86897 3272970 SH DFND 0 0 3272970 PENN NATL GAMING INC COM 707569109 342 27075 SH DFND 0 0 27075 PENN TREATY AMERN CORP COM NEW COM 707874400 0 125 SH DFND 0 0 125 PENSKE AUTOMOTIVE GRP INC COM 70959W103 1855 66253 SH DFND 0 0 66253 PENUMBRA INC COM 70975L107 512 3175 SH DFND 0 0 3175 PINDUODUO INC SPONSORED ADS 722304102 583 16188 SH DFND 0 0 16188 PINTEREST INC CL A 72352L106 208 13482 SH DFND 0 0 13482 POOL CORPORATION COM 73278L105 69954 355510 SH DFND 0 0 355510 PREVAIL THERAPEUTICS INC COM 74140Y101 0 5 SH DFND 0 0 5 PROLOGIS INC. COM 74340W103 1209 15042 SH DFND 0 0 15042 PROOFPOINT INC COM 743424103 4759 46391 SH DFND 0 0 46391 PURPLE INNOVATION INC COM 74640Y106 5519 971699 SH DFND 0 0 971699 Q2 HLDGS INC COM 74736L109 57863 979726 SH DFND 0 0 979726 QUANTERIX CORP COM 74766Q101 57523 3131375 SH DFND 0 0 3131375 QUIDEL CORP COM 74838J101 3777 38616 SH DFND 0 0 38616 QUOTIENT LTD SHS G73268107 2199 556814 SH DFND 0 0 556814 REDFIN CORP COM 75737F108 1203 78033 SH DFND 0 0 78033 REECE LIMITED NPV ISIN AU000000REH4 SEDOL 6728801 COM Q80528138 3328 597471 SH DFND 0 0 597471 REGENERON PHARMACEUTICALS COM 75886F107 3484 7135 SH DFND 0 0 7135 RENALYTIX AI PLC ORD GBP00025 REG S REG S ISIN GB00BYWL4Y04 COM G7489R108 534 195754 SH DFND 0 0 195754 REPLIGEN CORP COM 759916109 49647 514266 SH DFND 0 0 514266 RIGHTMOVE ORD GBP0001 ISIN GB00BGDT3G23 SEDOL BGDT3G2 COM G7565D106 5657 935978 SH DFND 0 0 935978 RINGCENTRAL INC CL A 76680R206 245160 1156908 SH DFND 0 0 1156908 ROKU INC COM CL A 77543R102 240316 2747097 SH DFND 0 0 2747097 SAFARICOM PLC KES005 ISIN KE1000001402 SEDOL B2QN3J6 COM V74587102 26749 106238516 SH DFND 0 0 106238516 SAFETY INS GROUP INC COM 78648T100 392 4645 SH DFND 0 0 4645 SALESFORCE COM INC COM 79466L302 75757 526166 SH DFND 0 0 526166 SAREPTA THERAPEUTICS INC COM 803607100 90805 928282 SH DFND 0 0 928282 SCORPIO TANKERS INC SHS Y7542C130 261 13632 SH DFND 0 0 13632 SEMLER SCIENTIFIC INC COM USD0001 COM 81684M104 3758 94184 SH DFND 0 0 94184 SENESTECH INC COM NEW 81720R208 90 43701 SH DFND 0 0 43701 SENSEONICS HLDGS INC COM 81727U105 9806 15478543 SH DFND 0 0 15478543 SERES THERAPEUTICS INC COM 81750R102 372 104269 SH DFND 0 0 104269 SERVICENOW INC COM 81762P102 29363 102461 SH DFND 0 0 102461 SHAKE SHACK INC CL A 819047101 83129 2202678 SH DFND 0 0 2202678 SHERWIN WILLIAMS CO COM 824348106 863 1879 SH DFND 0 0 1879 SHOCKWAVE MED INC COM 82489T104 47286 1425146 SH DFND 0 0 1425146 SHOPIFY INC CL A 82509L107 194034 465388 SH DFND 0 0 465388 SHOTSPOTTER INC COM 82536T107 57427 2089776 SH DFND 0 0 2089776 SI BONE INC COM 825704109 15623 1307330 SH DFND 0 0 1307330 SILK RD MED INC COM 82710M100 2532 80432 SH DFND 0 0 80432 SILVERCREST METALS INC COM 828363101 50252 9626887 SH DFND 0 0 9626887 SINTX TECHNOLOGIES INC COM NEW 829392307 0 71 SH DFND 0 0 71 SITEONE LANDSCAPE SUPPLY INC COM 82982L103 20531 278883 SH DFND 0 0 278883 SITIME CORP COM 82982T106 864 39671 SH DFND 0 0 39671 SLACK TECHNOLOGIES INC COM CL A 83088V102 57831 2154657 SH DFND 0 0 2154657 SMARTSHEET INC COM CL A 83200N103 236 5681 SH DFND 0 0 5681 SMILEDIRECTCLUB INC CL A COM 83192H106 6 1300 SH DFND 0 0 1300 SNAP INC CL A 83304A106 37478 3152061 SH DFND 0 0 3152061 SONOS INC COM 83570H108 443 52276 SH DFND 0 0 52276 SPLUNK INC COM 848637104 5977 47349 SH DFND 0 0 47349 SPOTIFY TECHNOLOGY S A SHS L8681T102 71220 586464 SH DFND 0 0 586464 SQUARE INC CL A 852234103 54259 1035881 SH DFND 0 0 1035881 SS&C TECHNOLOGIES HLDGS INC COM 78467J100 31437 717407 SH DFND 0 0 717407 STAAR SURGICAL CO COM PAR $0.01 852312305 7 206 SH DFND 0 0 206 STAMPS COM INC COM NEW 852857200 232 1784 SH DFND 0 0 1784 STAR BULK CARRIERS CORP. SHS PAR Y8162K204 108 19226 SH DFND 0 0 19226 STITCH FIX INC COM CL A 860897107 48 3754 SH DFND 0 0 3754 STOKE THERAPEUTICS INC COM 86150R107 38627 1686747 SH DFND 0 0 1686747 STONECO LTD COM CL A G85158106 26423 1213720 SH DFND 0 0 1213720 SUNTIMES MEDIA GROUP INC CLASS A COM USD001 NO STOCKHOLDER EQU COM 86688Q100 0 650 SH DFND 0 0 650 SVB FINANCIAL GROUP COM 78486Q101 4062 26884 SH DFND 0 0 26884 SVMK INC COM 78489X103 4177 309166 SH DFND 0 0 309166 T MOBILE US INC COM 872590104 74492 887868 SH DFND 0 0 887868 TACTILE SYS TECHNOLOGY INC COM 87357P100 179 4458 SH DFND 0 0 4458 TAL EDUCATION GROUP SPONSORED ADS 874080104 62753 1178244 SH DFND 0 0 1178244 TALON THERAPEUTICS CVR NEW COM 874CNT108 0 125 SH DFND 0 0 125 TANDEM DIABETES CARE INC COM NEW 875372203 81515 1266746 SH DFND 0 0 1266746 TELADOC HEALTH INC COM 87918A105 164021 1058131 SH DFND 0 0 1058131 TENCENT HOLDINGS LIMITED HKD000002 ISIN KYG875721634 SEDOL BM COM G87572163 69378 1414357 SH DFND 0 0 1414357 TESLA INC COM 88160R101 283356 540757 SH DFND 0 0 540757 THE A2 MILK COMPANY LTD NPV ISIN NZATME0002S8 SEDOL BWSRTS7 COM ZZCXTSUT2 2015 198288 SH DFND 0 0 198288 THOR INDS INC COM 885160101 2545 60332 SH DFND 0 0 60332 TRANSDIGM GROUP INC COM 893641100 4862 15185 SH DFND 0 0 15185 TRUPANION INC COM 898202106 17187 660295 SH DFND 0 0 660295 TWILIO INC CL A 90138F102 3579 39992 SH DFND 0 0 39992 TWIST BIOSCIENCE CORP COM 90184D100 433 14169 SH DFND 0 0 14169 TWITTER INC COM 90184L102 1930 78563 SH DFND 0 0 78563 UBER TECHNOLOGIES INC COM 90353T100 1141 40857 SH DFND 0 0 40857 VANECK VECTORS ETF TR GOLD MINERS ETF 92189F106 8794 381694 SH DFND 0 0 381694 VEEVA SYS INC CL A COM 922475108 9762 62432 SH DFND 0 0 62432 VERACYTE INC COM 92337F107 86682 3565676 SH DFND 0 0 3565676 VERIZON COMMUNICATIONS INC COM 92343V104 13008 242098 SH DFND 0 0 242098 VIRGIN GALACTIC HOLDINGS INC COM 92766K106 260 17577 SH DFND 0 0 17577 VISA INC COM CL A 92826C839 343 2131 SH DFND 0 0 2131 VULCAN MATLS CO COM 929160109 3605 33361 SH DFND 0 0 33361 WAYFAIR INC CL A 94419L101 608 11382 SH DFND 0 0 11382 WHEATON PRECIOUS METALS CORP COM 962879102 2190 79555 SH DFND 0 0 79555 WILLSCOT CORP COM 971375126 203 20000 SH DFND 0 0 20000 WORKDAY INC CL A 98138H101 17374 133424 SH DFND 0 0 133424 WUXI BIOLOGICS CAYMAN INC USD0000025 144A REG S ISIN KYG9700 COM G97008109 28340 2185656 SH DFND 0 0 2185656 XP INC CL A G98239109 8142 422104 SH DFND 0 0 422104 ZAI LAB LTD ADR 98887Q104 59617 1158066 SH DFND 0 0 1158066 ZILLOW GROUP INC CL A 98954M101 145 4274 SH DFND 0 0 4274 ZILLOW GROUP INC CL C CAP STK 98954M200 4733 131393 SH DFND 0 0 131393 ZOOM VIDEO COMMUNICATIONS IN CL A 98980L101 178500 1221596 SH DFND 0 0 1221596