<?xml version="1.0" encoding="us-ascii"?>
<!-- EDGAR Online I-Metrix Xcelerate Risk Return XBRL Instance Document, based on XBRL 2.1  http://www.edgar-online.com/ -->
<!-- Created (UTC): 12/12/2012 6:41:00 PM -->
<!-- XBRL File Set ID: 4a3c600d-9368-4de4-bc33-4b4f6e6e3988 -->
<!-- App Version: 3.0.0.183, 6.1.7601.65536, 14.0 -->
<!-- Copyright (c) 2005-2012 EDGAR Online, Inc. All Rights Reserved. -->
<xbrl xmlns="http://www.xbrl.org/2003/instance" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:ixt="http://www.xbrl.org/2008/inlineXBRL/transformation" xmlns:xbrldt="http://xbrl.org/2005/xbrldt" xmlns:rr="http://xbrl.sec.gov/rr/2010-02-28" xmlns:dei="http://xbrl.us/dei/2009-01-31" xmlns:xbrldi="http://xbrl.org/2006/xbrldi" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:iso4217="http://www.xbrl.org/2003/iso4217" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xbrli="http://www.xbrl.org/2003/instance" xmlns:ck0000892538="http://www.sunamerica.com/20121211">
  <link:schemaRef xlink:href="ck0000892538-20121211.xsd" xlink:type="simple" />
  <context id="DocumentContext" xmlns="http://www.xbrl.org/2003/instance">
    <entity>
      <identifier scheme="http://www.sec.gov/CIK">0000892538</identifier>
    </entity>
    <period>
      <startDate>2012-12-11</startDate>
      <endDate>2012-12-11</endDate>
    </period>
  </context>
  <context id="CTXT_P0001S000008099member_S000008099member" xmlns="http://www.xbrl.org/2003/instance">
    <entity>
      <identifier scheme="http://www.sec.gov/CIK">0000892538</identifier>
      <segment>
        <xbrldi:explicitMember dimension="dei:DocumentInformationDocumentAxis" xmlns:xbrldi="http://xbrl.org/2006/xbrldi">ck0000892538:P0001-S000008099Member</xbrldi:explicitMember>
        <xbrldi:explicitMember dimension="dei:LegalEntityAxis" xmlns:xbrldi="http://xbrl.org/2006/xbrldi">ck0000892538:S000008099Member</xbrldi:explicitMember>
      </segment>
    </entity>
    <period>
      <startDate>2012-12-11</startDate>
      <endDate>2012-12-11</endDate>
    </period>
  </context>
  <dei:DocumentType contextRef="DocumentContext">Other</dei:DocumentType>
  <dei:DocumentPeriodEndDate contextRef="DocumentContext">2012-12-11</dei:DocumentPeriodEndDate>
  <dei:EntityRegistrantName contextRef="DocumentContext">SUNAMERICA SERIES TRUST</dei:EntityRegistrantName>
  <dei:EntityCentralIndexKey contextRef="DocumentContext">0000892538</dei:EntityCentralIndexKey>
  <dei:AmendmentFlag contextRef="DocumentContext">false</dei:AmendmentFlag>
  <dei:DocumentCreationDate contextRef="DocumentContext">2012-12-11</dei:DocumentCreationDate>
  <dei:DocumentEffectiveDate contextRef="DocumentContext">2012-12-11</dei:DocumentEffectiveDate>
  <rr:ProspectusDate contextRef="DocumentContext">2012-04-30</rr:ProspectusDate>
  <rr:RiskReturnHeading contextRef="CTXT_P0001S000008099member_S000008099member">Emerging Markets Portfolio (the &#8220;Portfolio&#8221;)  &amp;nbsp;</rr:RiskReturnHeading>
  <ck0000892538:SupplementTextBlock contextRef="CTXT_P0001S000008099member_S000008099member">&lt;p class="MsoNormal" align="center" style="margin-top:0in;margin-right:0in;margin-left:0in;font-size:11.0pt;font-family:&apos;calibri&apos;,&apos;sans-serif&apos;;margin-bottom:0in;margin-bottom:.0001pt; text-align:center;line-height:normal;text-autospace:none"&gt;&lt;b&gt;&lt;font style=&apos;font-size:12.0pt;font-family:"Times New Roman","serif"&apos;&gt;&amp;nbsp;&lt;/font&gt;&lt;/b&gt;&lt;/p&gt;  &lt;p class="MsoNormal" align="center" style="margin-top:0in;margin-right:0in;margin-left:0in;font-size:11.0pt;font-family:&apos;calibri&apos;,&apos;sans-serif&apos;;margin-bottom:0in;margin-bottom:.0001pt; text-align:center;line-height:normal;text-autospace:none"&gt;&lt;b&gt;&lt;font style=&apos;font-size:12.0pt;font-family:"Times New Roman","serif"&apos;&gt;SUNAMERICA SERIES TRUST (the &#8220;Trust&#8221;)&lt;/font&gt;&lt;/b&gt;&lt;/p&gt;  &lt;p class="MsoNormal" align="center" style="margin-top:0in;margin-right:0in;margin-left:0in;font-size:11.0pt;font-family:&apos;calibri&apos;,&apos;sans-serif&apos;;margin-bottom:0in;margin-bottom:.0001pt; text-align:center;line-height:normal;text-autospace:none"&gt;&lt;b&gt;&lt;font style=&apos;font-size:12.0pt;font-family:"Times New Roman","serif"&apos;&gt;Emerging Markets Portfolio (the &#8220;Portfolio&#8221;)&lt;/font&gt;&lt;/b&gt;&lt;/p&gt;  &lt;p class="MsoNormal" align="center" style="font-size:11.0pt;font-family:&apos;calibri&apos;,&apos;sans-serif&apos;;margin-top:9.0pt;margin-right:0in; margin-bottom:0in;margin-left:0in;margin-bottom:.0001pt;text-align:center; line-height:normal;text-autospace:none"&gt;&lt;b&gt;&lt;font style=&apos;font-size:12.0pt; font-family:"Times New Roman","serif"&apos;&gt;Supplement to the Statutory Prospectus dated April&amp;nbsp;30, 2012&lt;/font&gt;&lt;/b&gt;&lt;/p&gt;  &lt;p class="MsoNormal" style="font-size:11.0pt;font-family:&apos;calibri&apos;,&apos;sans-serif&apos;;margin-top:9.0pt;margin-right:0in;margin-bottom:0in; margin-left:0in;margin-bottom:.0001pt;line-height:normal;text-autospace:none"&gt;&lt;font style=&apos;font-size:12.0pt;font-family:"Times New Roman","serif"&apos;&gt;Under the heading &lt;i&gt;&#8220;Principal Investment Strategies of the Portfolio&lt;/i&gt; &#8221; in the Summary Section the disclosure is deleted and replaced with the following: &lt;/font&gt;&lt;/p&gt;  &lt;p class="MsoNormal" style="font-size:11.0pt;font-family:&apos;calibri&apos;,&apos;sans-serif&apos;;margin-top:9.0pt;margin-right:40.3pt;margin-bottom: 0in;margin-left:40.3pt;margin-bottom:.0001pt;line-height:normal;text-autospace: none"&gt;&lt;font style=&apos;font-size:12.0pt;font-family:"Times New Roman","serif"&apos;&gt;The Portfolio attempts to achieve its goal by investing, under normal circumstances, at least 80% of its net assets in common stocks, depositary receipts and other equity securities of companies primarily in emerging markets outside the U.S., which the subadviser believes, when compared to developed markets, have above average growth prospects.&lt;/font&gt;&lt;/p&gt;  &lt;p class="MsoNormal" style="font-size:11.0pt;font-family:&apos;calibri&apos;,&apos;sans-serif&apos;;margin-top:9.0pt;margin-right:40.3pt;margin-bottom: 0in;margin-left:40.3pt;margin-bottom:.0001pt;line-height:normal;text-autospace: none"&gt;&lt;font style=&apos;font-size:12.0pt;font-family:"Times New Roman","serif"&apos;&gt;Emerging markets include most countries in the world except Australia, Canada, Japan, New Zealand, the United Kingdom, the United States, and most of the countries of Western Europe. An emerging market company is one: that is organized under the laws of, or has a principal place of business in an emerging market; where the principal securities market is in an emerging market; that derives at least 50% of its total revenues or profits from goods that are produced or sold, investments made, or services performed in an emerging market; or at least 50% of the assets of which are located in an emerging market. The Portfolio is not required to allocate its investments in any set percentages to any particular country. The Portfolio is not constrained by capitalization or style limits and will invest across sectors. The Portfolio will invest in securities across all market capitalizations, although the Portfolio may invest a significant portion of its assets in companies of one particular market capitalization category.&lt;/font&gt;&lt;/p&gt;  &lt;p class="MsoNormal" style="font-size:11.0pt;font-family:&apos;calibri&apos;,&apos;sans-serif&apos;;margin-top:11.25pt;margin-right:40.3pt;margin-bottom: 0in;margin-left:40.3pt;margin-bottom:.0001pt;line-height:normal;text-autospace: none"&gt;&lt;font style=&apos;font-size:12.0pt;font-family:"Times New Roman","serif"&apos;&gt;The Portfolio may overweight or underweight countries relative to its benchmark, the Morgan Stanley Capital International (MSCI) Emerging Markets Index. In managing the Portfolio, the subadviser adheres to a disciplined process for stock selection and portfolio construction. A proprietary multi-factor model is used to quantitatively rank securities in the Portfolio&#8217;s investment universe which the adviser uses to select securities. The Portfolio emphasizes securities that are ranked as undervalued, while underweighting or avoiding securities that appear overvalued.&lt;/font&gt;&lt;/p&gt;  &lt;p class="MsoNormal" style="font-size:11.0pt;font-family:&apos;calibri&apos;,&apos;sans-serif&apos;;margin-top:9.0pt;margin-right:40.3pt;margin-bottom: 0in;margin-left:40.3pt;margin-bottom:.0001pt;line-height:normal;text-autospace: none"&gt;&lt;font style=&apos;font-size:12.0pt;font-family:"Times New Roman","serif"&apos;&gt;The Portfolio may invest in securities denominated in U.S. dollars, major reserve currencies and currencies of other countries in which it is permitted to invest. The Portfolio typically maintains full currency exposure to those markets in which it invests. However, the Portfolio may hedge a portion of its foreign currency exposure into the U.S. dollar.&lt;/font&gt;&lt;/p&gt;  &lt;p class="MsoNormal" style="margin-top:0in;margin-right:0in;margin-left:0in;margin-bottom:10.0pt;line-height:115%;font-size:11.0pt;font-family:&apos;calibri&apos;,&apos;sans-serif&apos;;"&gt;&amp;nbsp;&lt;/p&gt;</ck0000892538:SupplementTextBlock>
  <link:footnoteLink xlink:type="extended" xlink:role="http://www.xbrl.org/2003/role/link">
  </link:footnoteLink>
</xbrl>
