Exhibit 4.1

TransEnterix, Inc. TM TransEnterix, Inc. INCORPORATED UNDER COMMON THE LAWS STOCK OF THE STATE OF DELAWARE SEE REVERSE FOR CERTAIN DEFINITIONS CUSIP 89366M 10 2 THIS IS TO CERTIFY that is the owner of TransEnterix, Inc. (hereinafter called the “Corporation”), transferable on the books of the Corporation by the holder hereof in person or by duly authorized attorney upon surrender of this Certificate properly endorsed. This Certificate is not valid until countersigned and registered by the Transfer Agent and Registrar. WITNESS the facsimile signatures of the duly authorized officers of the Corporation. Dated: Corporate Secretary President and Chief Executive Officer Countersigned CONTINENTAL and Registered: STOCK TRANSFER & TRUST COMPANY (Jersey City, N. J.) Transfer Agent and Registrar By Authorized Officer ABnote North America COLUMBIA, 711 ARMSTRONG TENNESSEE LANE 38401 PROOF TRANSENTERIX, OF: DECEMBER INC. 5, 2013 (931) 388-3003 WO- 7864 FACE SALES: HOLLY GRONER 931-490-7660 OPERATOR: NEW DKS However, COLOR: This it is not proof an was exact printed color from rendition, a digital and file the or final artwork printed on product a graphics may quality, appear color slightly laser different printer. from It is a the good proof representation due to the difference of the color between as it will the appear dyes and on the printing final ink. product. NOTE: TEXT RECEIVED BY MODEM OR E-MAIL IS NOT PROOFREAD WORD FOR WORD. PLEASE INITIAL THE APPROPRIATE SELECTION FOR THIS PROOF: OK AS IS OK WITH CHANGES MAKE CHANGES AND SEND ANOTHER PROOF S NUMBER SHARES AMERICAN BANK NOTE COMPANY Joshna B. Weergand jodd m. pope

The following abbreviations, when used in the inscription on the face of this certificate, shall be construed as though they were written out in full according to applicable laws or regulations: TEN COM – as tenants IN COMMON TEN ENT – as tenants by the entireties JT TEN – as joint tenants with right of survivorship and not as tenants in common Additional abbreviations may also be used though not in the above list. UNIF GIFT MIN ACT – Custodian (Cust) (Minor) Act under Uniform Gifts to Minors (State) Signature(s) Guaranteed: THE SIGNATURE(S) SHOULD BE GUARANTEED BY AN ELIGIBLE GUARANTOR INSTITUTION (BANKS, STOCKBROKERS,SAVINGS AND LOAN ASSOCIATIONS AND CREDIT UNIONS WITH MEMBERSHIP IN AN APPROVED SIGNATURE GUARANTEE MEDALLION PROGRAM), PURSUANT TO S.E.C. RULE 17Ad-15.
For Value Received, herebyself, assign and
PLEASE INSERT SOCIAL SECURITY OR OTHER IDENTIFYING NUMBER OF ASSIGNEE
(PLEASE TYPEWRITE NAME AND ADDRESS)
Shares of the stock represented by the within certificate and do hereby irrevocably constitute and appoint
Attorney, TO transfer the same on the books of the within-named corporation, with full power of subsituation in the premises.
Dated
Notice: The signature to this Assignment must correspond with the name as written upon the face of the Certificate in every particular, without alteration or enlargement or any change whatever.
ABnote North America
711 ARMSTRONG LANE
COLUMBIA, TENNESSEE 38401
(931) 388-3003
HOLLY GRONER 931-490-7660
PROOF OF: DECEMBER 5, 2013
TRANSENTERIX, INC.
WO- 7864 BACK
OPERATOR: DKS
NEW
PLEASE INITIAL THE APPROPRIATE SELECTION FOR THIS PROOF: OK AS IS OK WITH CHANGES MAKE CHANGES AND SEND ANOTHER PROOF
PREVIOUSLY PRINTED CERTIFICATE SCANNED FOR PROOFING.