497 1 a13-20535_12497.htm 497



522 Fifth Avenue

New York, New York 10036




October 8, 2013


Securities and Exchange Commission

100 F Street, N.E.

Washington, D.C. 20549


Re:                             Morgan Stanley Institutional Fund, Inc.

File Nos. 033-23166; 811-05624


Ladies and Gentlemen:


On behalf of Morgan Stanley Institutional Fund, Inc. (“Registrant”), we hereby submit for filing pursuant to Rule 497(e) under the Securities Act of 1933, as amended, exhibits containing interactive data format risk/return summary information for the Registrant. These exhibits contain the risk/return summary information in the prospectus for the Registrant dated August 19, 2013. The purpose of this filing is to submit the XBRL information from the 497(e) filing dated September 17, 2013 for the Registrant.


If you have any questions, please feel free to contact me at 212.296.6983 (tel.) or 646.452.4799 (fax).



Very truly yours,




/s/ Tara A. Farrelly


Tara A. Farrelly


Assistant Secretary



cc: Stefanie V. Chang Yu, Esq.