SEC FORM 4

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

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Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

1. Name and Address of Reporting Person^*

Struve Clayton A

(Last)

(First)

(Middle)

175 W JACKSON BLVD

SUITE 440

(Street)

CHICAGO

60604

(City)

(State)

(Zip)

2. Issuer Name and Ticker or Trading Symbol
PRESSURE BIOSCIENCES INC [ PBIO ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

Director	X	10% Owner
Officer (give title below)		Other (specify below)

3. Date of Earliest Transaction (Month/Day/Year)
04/10/2012

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

	Form filed by One Reporting Person
X	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	Code	V	Amount	(A) or (D)	Price		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
Common Stock	04/10/2012		P		2,000	A	$0.55	102,585	I	Reporting Person is a member manager of CCS, LLC⁽¹⁾
Common Stock	04/11/2012		P		4,000	A	$0.55	106,585	I	Reporting Person is a member manager of CCS, LLC⁽¹⁾
Common Stock	04/13/2012		P		2,000	A	$0.6	108,585	I	Reporting Person is a member manager of CCS, LLC⁽¹⁾
Common Stock	04/16/2012		P		4,000	A	$0.53	112,585	I	Reporting Person is a member manager of CCS, LLC⁽¹⁾
Common Stock	04/19/2012		P		9,200	A	$0.4565	121,785	I	Reporting Person is a member manager of CCS, LLC⁽¹⁾
Common Stock	04/20/2012		P		2,000	A	$0.52	123,785	I	Reporting Person is a member manager of CCS, LLC⁽¹⁾
Common Stock	04/25/2012		P		8,000	A	$0.41	131,785	I	Reporting Person is a member manager of CCS, LLC⁽¹⁾
Common Stock	04/24/2012		P		2,000	A	$0.47	133,785	I	Reporting Person is a member manager of CCS, LLC⁽¹⁾
Common Stock	05/10/2012		P		4,000	A	$0.42	137,785	I	Reporting Person is a member manager of CCS, LLC⁽¹⁾
Common Stock	05/11/2012		P		2,000	A	$0.42	139,785	I	Reporting Person is a member manager of CCS, LLC⁽¹⁾
Common Stock	05/14/2012		P		2,000	A	$0.4	141,785	I	Reporting Person is a member manager of CCS, LLC⁽¹⁾
Common Stock	06/06/2012		P		150	A	$0.21	141,935	I	Reporting Person is a member manager of CCS, LLC⁽¹⁾
Common Stock	06/18/2012		P		5,000	A	$0.25	146,935	I	Reporting Person is a member manager of CCS, LLC⁽¹⁾
Common Stock	07/23/2012		P		2,000	A	$0.28	148,935	I	Reporting Person is a member manager of CCS, LLC⁽¹⁾
Common Stock	08/28/2012		P		2,000	A	$0.28	150,935	I	Reporting Person is a member manager of CCS, LLC⁽¹⁾
Common Stock	09/04/2012		P		2,000	A	$0.29	152,935	I	Reporting Person is a member manager of CCS, LLC⁽¹⁾
Common Stock	09/10/2012		P		10,000	A	$0.28	162,935	I	Reporting Person is a member manager of CCS, LLC⁽¹⁾
Common Stock	09/18/2012		P		2,000	A	$0.25	164,935	I	Reporting Person is a member manager of CCS, LLC⁽¹⁾
Common Stock	09/28/2012		J⁽²⁾		27,816	A	$0⁽³⁾	1,051,665	D
Common Stock	10/04/2012		P		10,000	A	$0.29	174,935	I	Reporting Person is a member manager of CCS, LLC⁽¹⁾
Common Stock	10/08/2012		P		2,000	A	$0.29	176,935	I	Reporting Person is a member manager of CCS, LLC⁽¹⁾

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares	8. Price of Derivative Security (Instr. 5)		10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
Series C Common Stock Purchase Warrant	$0.74	07/06/2012⁽⁴⁾		J⁽⁴⁾			311,925	⁽⁴⁾	08/07/2017	Common Stock⁽⁵⁾	311,925⁽⁵⁾	⁽⁴⁾	0	D
Series C Common Stock Purchase Warrant	$0.6	07/06/2012⁽⁴⁾		J⁽⁴⁾		311,925		⁽⁴⁾	08/07/2017	Common Stock⁽⁵⁾	311,925⁽⁵⁾	⁽⁴⁾	311,925	D
Promissory Note - Aug 2011 Common Stock Warrant	$0.85	07/06/2012⁽⁶⁾		J⁽⁶⁾			211,765	⁽⁶⁾	08/03/2014	Common Stock⁽⁷⁾	211,765⁽⁷⁾	⁽⁶⁾	0	D
Promissory Note - Aug 2011 Common Stock Warrant	$0.6	07/06/2012⁽⁶⁾		J⁽⁶⁾		211,765		⁽⁶⁾	08/03/2014	Common Stock⁽⁷⁾	211,765⁽⁷⁾	⁽⁶⁾	211,765	D
Promissory Note - Aug 2011 Common Stock Warrant	$0.76	07/06/2012⁽⁸⁾		J⁽⁸⁾			26,316	⁽⁸⁾	08/03/2014	Common Stock⁽⁷⁾	26,316⁽⁷⁾	⁽⁸⁾	0	D
The reported transactions involved an amendment of an outsta	$0.6	07/06/2012⁽⁸⁾		J⁽⁸⁾		26,316		⁽⁸⁾	08/03/2014	Common Stock⁽⁷⁾	26,316⁽⁷⁾	⁽⁸⁾	23,316	D
February 2012 Common Stock Purchase Warrant	$0.74	07/06/2012⁽⁴⁾		J⁽⁴⁾			200,001	⁽⁴⁾	08/07/2012	Common Stock⁽⁹⁾	200,001⁽⁹⁾	⁽⁴⁾	0	D
February 2012 Common Stock Warrant	$0.6	07/06/2012⁽⁴⁾		J⁽⁴⁾		200,001		⁽⁴⁾	08/07/2017	Common Stock⁽⁹⁾	200,001⁽⁹⁾	⁽⁴⁾	200,001	D

1. Name and Address of Reporting Person^*

Struve Clayton A

(Last)

(First)

(Middle)

175 W JACKSON BLVD

SUITE 440

(Street)

CHICAGO

60604

(City)

(State)

(Zip)

Relationship of Reporting Person(s) to Issuer

Director	X	10% Owner
Officer (give title below)		Other (specify below)

1. Name and Address of Reporting Person^*

CSS LLC/IL

(Last)

(First)

(Middle)

175 WEST JACKSON BLVD

SUITE 440

(Street)

CHICAGO

60604

(City)

(State)

(Zip)

Relationship of Reporting Person(s) to Issuer

Director		10% Owner
Officer (give title below)	X	Other (specify below)
		(a)

Explanation of Responses:

1. Reporting Person, Clayton Struve, is an Indirect Owner as Member Manager of CSS, LLC of shares purchased by CSS, LLC. CSS,LLC disclaims any beneficial ownership (direct or indirect) of shares held directly by Reporting Person, Clayton Struve.

2. Dividend shares as a result of investment in Series C Preferred shares.

3. Dividend accrual of $22,322 at a rate of .8025 or 27,816 shares

4. The reported transactions involved an amendment of an outstanding warrant, resulting in the deemed cancellation of the old warrant at an exercise price of $0.74 and the grant of a replacement warrant at an exercise price of $0.60.

5. The Series C Common Stock Purchase Warrants contain a limitation on exercise which prevents the Reporting Person from exercising any Warrants if, after giving effect to the exercise, the Reporting Person would beneficially own more than 4.99% of the outstanding shares of Common Stock. The Reporting Person may elect to increase this limitation to 9.99%, 14.99% or 19.99%, upon not less than 61 days prior written notice to the Company. Since the Reporting Person currently beneficially owns more than 9.99% but less than 14.99% of the outstanding shares of Common Stock, the conversion limitation that applies to the Reporting Person is the 14.99% limitation. The Reporting Person disclaims beneficial ownership of such securities except to the extent of the Reporting Person's pecuniary interest in such securities

6. The reported transactions involved an amendment of an outstanding warrant, resulting in the deemed cancellation of the old warrant at an exercise price of $0.85 and the grant of a replacement warrant at an exercise price of $0.60.

7. The Promissory Note-Aug 2011 Common Stock Purchase Warrants contain a limitation on exercise which prevents the Reporting Person from exercising any Warrants if, after giving effect to the exercise, the Reporting Person would beneficially own more than 4.99% of the outstanding shares of Common Stock. The Reporting Person may elect to increase this limitation to 9.99%, 14.99% or 19.99%, upon not less than 61 days prior written notice to the Company. Since the Reporting Person currently beneficially owns more than 9.99% but less than 14.99% of the outstanding shares of Common Stock, the conversion limitation that applies to the Reporting Person is the 14.99% limitation. The Reporting Person disclaims beneficial ownership of such securities except to the extent of the Reporting Person's pecuniary interest in such securities

8. The reported transactions involved an amendment of an outstanding warrant, resulting in the deemed cancellation of the old warrant at an exercise price of $0.76 and the grant of a replacement warrant at an exercise price of $0.60

9. The February 2012 Common Stock Purchase Warrants contain a limitation on exercise which prevents the Reporting Person from exercising any Warrants if, after giving effect to the exercise, the Reporting Person would beneficially own more than 4.99% of the outstanding shares of Common Stock. The Reporting Person may elect to increase this limitation to 9.99%, 14.99% or 19.99%, upon not less than 61 days prior written notice to the Company. Since the Reporting Person currently beneficially owns more than 9.99% but less than 14.99% of the outstanding shares of Common Stock, the conversion limitation that applies to the Reporting Person is the 14.99% limitation. The Reporting Person disclaims beneficial ownership of such securities except to the extent of the Reporting Person's pecuniary interest in such securities

Remarks:

(a) Reporting Person Clayton A. Struve is a member of manager of CSS, LLC and has indirect beneficial ownership of shares of stock held in the name of CSS, LLC. CSS, LLC disclaims any beneficial ownership (direct or indirect) of shares held directly by Reporting Person, Clayton Struve.

	Clayton A. Struve	11/20/2012
	Mitchell R. Bialek	11/20/2012
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
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