EX-99 2 v200593_ex99.htm Unassociated Document
EXHIBIT 99
 
PFIZER REPORTS THIRD-QUARTER 2010 RESULTS

§
Third-Quarter 2010 Revenues of $16.2 Billion

§
Third-Quarter 2010 Adjusted Diluted EPS(1) of $0.54; Reported Diluted EPS(2) of $0.11

§
Tightens Ranges for 2010 Financial Guidance Components, Increases Range for Adjusted Diluted EPS(1) and Reduces Range for Reported Diluted EPS(2); Reaffirms 2012 Financial Targets

§
Advances Strategic Priorities with Agreement to Acquire King Pharmaceuticals, Inc., Acquisition of  FoldRx, Alliance with Biocon and Pending Alliance with Laboratorio Teuto Brasileiro S.A.; Reviewing Alternatives for Capsugel
 
($ in millions, except per share amounts)
 
   
Third-Quarter
   
Year-to-Date
 
   
2010
   
2009
   
Change
   
2010
   
2009
   
Change
 
Reported Revenues
  $ 16,171     $ 11,621       39 %   $ 50,248     $ 33,472       50 %
Reported Net Income(2)
    866       2,878       (70 %)     5,367       7,868       (32 %)
Reported Diluted EPS(2)
    0.11       0.43       (74 %)     0.66       1.16       (43 %)
Adjusted Income(1)
    4,372       3,461       26 %     14,213       10,377       37 %
Adjusted Diluted EPS(1)
    0.54       0.51       6 %     1.76       1.54       14 %
 
See end of text prior to tables for notes.
 
NEW YORK, N.Y., Tuesday, November 2, 2010 – Pfizer Inc. (NYSE: PFE) today reported financial results for third-quarter 2010.  Since the acquisition of Wyeth was completed on October 15, 2009, legacy Wyeth products and operations are reflected in the first three quarters of 2010, but not reflected in the first three quarters of 2009.  Third-quarter 2010 revenues were $16.2 billion, an increase of 39% compared with $11.6 billion in the year-ago quarter.  Revenues for third-quarter 2010 compared with the year-ago quarter were favorably impacted by $5.2 billion, or 44%, due to the addition of the legacy Wyeth products, negatively impacted by $458 million, or 4%, due to legacy Pfizer products, and negatively impacted by $160 million, or 1%, due to foreign exchange.  For third-quarter 2010, U.S. revenues were $7.1 billion, an increase of 48% compared with the year-ago quarter.  International revenues were $9.1 billion, an increase of 33% compared with the prior-year quarter, which reflected 35% operational growth partially offset by a 2% unfavorable impact of foreign exchange.  U.S. revenues represented 44% of total revenues in third-quarter 2010 compared with 41% in the year-ago quarter, while international revenues represented 56% of total revenues in third-quarter 2010 compared with 59% in the year-ago quarter.

 
- 1 -

 
 
For the first nine months of 2010, revenues were $50.2 billion, an increase of 50% compared with $33.5 billion in the same period in 2009.   Revenues for the first nine months of  2010 compared with the year-ago period were favorably impacted by $15.9 billion, or 48%, due to the addition of the legacy Wyeth products, and by $1.2 billion, or 3%, due to foreign exchange, and negatively impacted by $285 million, or 1%, due to legacy Pfizer products.  U.S. revenues were $21.8 billion, an increase of 52% compared with the first nine month of 2009.  International revenues were $28.4 billion, an increase of 48% compared with the same period last year, which reflected 42% operational growth and a 6% favorable impact of foreign exchange.  U.S. revenues represented 43% and international revenues represented 57% of total revenues in the first nine months of 2010, comparable with the first nine months of 2009.

Business Revenues
Pfizer operates two distinct commercial organizations: Biopharmaceutical and Diversified.  Biopharmaceutical includes the Primary Care, Specialty Care, Established Products, Emerging Markets and Oncology customer-focused units, while Diversified includes Animal Health, Consumer Healthcare, Nutrition and Capsugel.
 
   
Third-Quarter(13)
 
                           
Operational
 
($ in millions)
 
2010
   
2009(13)
   
Change
   
Foreign
Exchange
   
Total
   
Legacy
Pfizer
 
                                     
Primary Care(3)
  $ 5,653     $ 5,540       2 %     (1 %)     3 %     (3 %)
Specialty Care(4)
    3,717       1,577       136 %     (6 %)     142 %     (1 %)
Established Products(5)
    2,168       1,657       31 %     (1 %)     32 %     (13 %)
Emerging Markets(6)
    2,072       1,529       36 %     2 %     34 %      
Oncology(7)
    335       374       (10 %)     (4 %)     (6 %)     (15 %)
Biopharmaceutical
    13,945       10,677       31 %     (2 %)     33 %     (4 %)
                                                 
Animal Health(8)
    860       678       27 %     (1 %)     28 %     5 %
Consumer Healthcare(9)
    673             N/ A     N/ A     N/ A     N/ A
Nutrition(10)
    441             N/ A     N/ A     N/ A     N/ A
Capsugel(11)
    176       177       (1 %)     (3 %)     2 %     2 %
Diversified
    2,150       855       151 %           151 %     4 %
Other(12)
    76       89       (15 %)     16 %     (31 %)     (31 %)
Total
  $ 16,171     $ 11,621       39 %     (1 %)     40 %     (4 %)
See end of text prior to tables for notes.
N/A – Not applicable

 
- 2 -

 
 
For third-quarter 2010, revenues from Biopharmaceutical were $13.9 billion, an increase of 31% compared with $10.7 billion in the year-ago quarter.  Operationally, revenues increased $3.4 billion, or 33%, which included $3.9 billion, or 37%, attributable to legacy Wyeth products, primarily Premarin in the Primary Care unit, Enbrel and the Prevnar/Prevenar franchise in the Specialty Care unit, Protonix and Zosyn/Tazocin in the Established Products unit as well as Enbrel and the Prevenar franchise in the Emerging Markets unit, partially offset by a decline of $468 million, or 4%, due to legacy Pfizer products.  In addition, foreign exchange unfavorably impacted Biopharmaceutical revenues by 2% or $173 million.
 
Within the Biopharmaceutical units, legacy Pfizer operational performance was impacted in third-quarter 2010 compared with the year-ago quarter primarily by the loss of exclusivity of certain products and by the resulting reclassification of Camptosar European revenues among the units. Legacy Pfizer Primary Care unit revenues in third-quarter 2010 were negatively impacted by 4% due to the loss of exclusivity of Lipitor in Canada in May 2010 and in Spain in July 2010. Legacy Pfizer Oncology unit revenues no longer include Camptosar’s European revenues due to its loss of exclusivity in July 2009. Camptosar’s European revenues are included in the Established Products unit beginning in first-quarter 2010. This reclassification of revenues negatively impacted the legacy Pfizer Oncology unit’s performance by 16% in third-quarter 2010 compared with the prior-year quarter. Further, legacy Pfizer Established Products unit revenues in third-quarter 2010 were adversely impacted by 6% due to the loss of exclusivity for Norvasc in Canada in July 2009, partially offset by the favorable impact of 1% due to the addition of Camptosar’s European revenues. Finally, legacy Pfizer Emerging Markets unit revenues in third-quarter 2010 were essentially flat reflecting solid growth in key priority countries, most notably China, offset by Eastern European pricing pressure and wholesaler purchasing patterns driven by economic conditions.
 
For third-quarter 2010, revenues from Diversified were $2.2 billion, an increase of 151% compared with $855 million in the year-ago quarter.  This increase of $1.3 billion was primarily attributable to legacy Wyeth products, principally Centrum, Advil and Caltrate in Consumer Healthcare and infant and toddler Nutrition products.  The impact of foreign exchange on Diversified revenues was immaterial.

 
- 3 -

 
 
Reported Net Income(2) and Reported Diluted EPS(2)
For third-quarter 2010, Pfizer posted reported net income(2) of $866 million, a decrease of 70% compared with $2.9 billion in the prior-year quarter, and reported diluted EPS(2) of $0.11, a decrease of 74% compared with $0.43 in the prior-year quarter.  For the first nine months of 2010, Pfizer posted reported net income(2) of $5.4 billion, a decrease of 32% compared with $7.9 billion in the first nine months of 2009, and reported diluted EPS(2) of $0.66, a decline of 43% compared with $1.16 in the prior-year period.  Third-quarter 2010 results were favorably impacted by revenues from legacy Wyeth products, and negatively impacted primarily by the expenses associated with the legacy Wyeth operations as well as purchase accounting adjustments, integration charges and restructuring charges associated with the Wyeth acquisition, impairment charges of $1.5 billion (pre-tax) related to certain intangible assets acquired in connection with the Wyeth acquisition and a $701 million (pre-tax) charge for asbestos litigation related to our wholly owned subsidiary Quigley Company, Inc.  For the first nine months of 2010, results were impacted by the aforementioned items as well as the favorable impact of foreign exchange and the unfavorable impact of higher net interest expense primarily due to borrowings used to partially fund the Wyeth acquisition.

In addition, the effective tax rate on reported results increased to approximately 39% in third-quarter 2010 from approximately 28% in third-quarter 2009, and approximately 37% in the first nine months of 2010 from approximately 27% in the first nine months of 2009.  These increases were primarily the result of higher expenses incurred as a result of the acquisition of Wyeth and the mix of jurisdictions in which those expenses were incurred.  Also, the lower rates in the third quarter and first nine months of 2009 compared to the same periods in 2010 reflected a tax benefit of $174 million related to the final resolution of a previously disclosed settlement.

Additionally, reported diluted EPS(2) in third-quarter 2010 and the first nine months of 2010 was impacted by the increased number of shares outstanding in comparison with the corresponding periods in 2009 resulting from shares issued to partially fund the Wyeth acquisition.

 
- 4 -

 
 
Adjusted Income(1) and Adjusted Diluted EPS(1)
Third-quarter 2010 adjusted income(1) was $4.4 billion, an increase of 26% compared with $3.5 billion in the year-ago quarter, and adjusted diluted EPS(1) was $0.54, an increase of 6% compared with $0.51 in the year-ago quarter.  For the first nine months of 2010, Pfizer posted adjusted income(1) of $14.2 billion, an increase of 37% compared with $10.4 billion in the first nine months of 2009, and adjusted diluted EPS(1) of $1.76, an increase of 14% compared with $1.54 in the prior-year period.  Results were favorably impacted by revenues from legacy Wyeth products and, to a lesser extent, foreign exchange, which were partially offset by the expenses associated with the legacy Wyeth operations as well as lower overall revenues from legacy Pfizer products and higher net interest expense primarily due to borrowings used to partially fund the acquisition of Wyeth.

In addition, the effective tax rate on adjusted income(1) decreased to approximately 30% in third-quarter 2010 compared with approximately 32% in third-quarter 2009, and increased to approximately 31% in the first nine months of 2010 compared with approximately 30% in the first nine months of 2009.  The changes in the effective tax rate on adjusted income(1) were primarily the result of the change in the jurisdictional mix of earnings in the respective periods. 

Additionally, adjusted diluted EPS(1) in third-quarter 2010 and the first nine months of 2010 was impacted by the increased number of shares outstanding in comparison with the corresponding periods in 2009 resulting from shares issued to partially fund the Wyeth acquisition.
 
In third-quarter 2010, adjusted cost of sales(1) as a percentage of revenues was 18.3% compared with 15.4% in third-quarter 2009. This increase primarily reflects the change in the mix of products and businesses as a result of the Wyeth acquisition. Excluding the impact of foreign exchange, adjusted cost of sales(1) as a percentage of revenues was 19.7% in third-quarter 2010.
 
Adjusted SI&A expenses(1) were $4.6 billion in third-quarter 2010, an increase of 43% compared with $3.2 billion in the prior-year quarter.  This increase was attributable primarily to the addition of the legacy Wyeth operations.  Foreign exchange decreased third-quarter 2010 adjusted SI&A expenses(1) by $32 million compared with the year-ago quarter.

Adjusted R&D expenses(1) were $2.2 billion in third-quarter 2010, an increase of 33% compared with $1.6 billion in the prior-year period. This increase was attributable primarily to the addition of the legacy Wyeth operations and continued investment in the late-stage development portfolio.  Foreign exchange decreased third-quarter 2010 adjusted R&D expenses(1) by $15 million compared with the year-ago quarter.

 
- 5 -

 
 
Overall, foreign exchange decreased adjusted total costs(14) by $298 million, or 4%, in third-quarter 2010 compared with the prior-year period.

Executive Commentary
Jeff Kindler, Chairman and Chief Executive Officer, stated, “It’s been just over a year since the closing of the Wyeth acquisition.  I am particularly pleased with the speed of the integration, the cost synergies achieved to date as well as our solid financial performance this quarter and year-to-date in this difficult economic environment.  This combination is clearly creating opportunities to provide greater value for our shareholders.”

“We continue to carefully evaluate and make prudent capital allocation decisions.  We recently announced several business development transactions that we believe will enhance shareholder value by enabling continued growth in several of our business units.  Our pending acquisition of King Pharmaceuticals, Inc. is consistent with our stated objective of seeking a larger presence in the pain market within the Primary Care unit, while our acquisition of FoldRx enhances the orphan and rare disease pipeline portfolio of our Specialty Care unit.  Further, our alliance with Biocon is expected to advance our biosimilars strategy by positioning us competitively in the diabetes market over time, while our agreement with Laboratorio Teuto Brasileiro S.A. is expected to broaden our Emerging Markets presence.  Also, we are reviewing strategic alternatives for Capsugel in order to optimize the value of this asset.  We believe these actions, taken together, will serve to improve our business profile and provide both near-term and longer-term financial benefit,” continued Mr. Kindler.

Frank D’Amelio, Chief Financial Officer, stated, “Given our solid year-to-date performance and continued confidence in the business, we are once again reaffirming our 2012 financial targets, and we are narrowing the ranges for the components of our 2010 financial guidance.  Additionally, we are increasing our 2010 adjusted diluted EPS(1) guidance to a range of  $2.17 to $2.22 from a range of $2.10 to $2.20.  Further, we repurchased approximately $500 million, or 30 million shares, of our common stock in the third quarter, and we continue to review our capital allocation options with the goal of maximizing value for our shareholders.”

 
- 6 -

 
 
2010 Financial Guidance(16)
For full-year 2010, Pfizer’s financial guidance, at current exchange rates(15), is summarized below.
Reported Revenues
 
$67.0 to $68.0 billion
(previously $67.0 to $69.0 billion)
Adjusted Cost of Sales(1) as a Percentage of Revenues
 
18.5% to 19.0%
(previously 19.0% to 20.0%)
Adjusted SI&A Expenses(1)
 
$19.2 to $19.7 billion
(previously $19.0 to $20.0 billion)
Adjusted R&D Expenses(1)
 
$9.1 to $9.5 billion
(previously $9.1 to $9.6 billion)
Adjusted Other (Income)/Deductions(1)
 
Approximately $1.0 billion
(previously $1.2 to $1.4 billion)
Effective Tax Rate on Adjusted Income(1)
 
Approximately 30%
Reported Diluted EPS(2)
 
$0.84 to $0.94
 (previously $0.95 to $1.10)
Adjusted Diluted EPS(1)
  
$2.17 to $2.22
(previously $2.10 to $2.20)

2012 Financial Targets
The Company is reaffirming all elements of its 2012 financial targets.  As previously stated, given the longer-term nature of these targets, they are subject to greater variability and less certainty as a result of potential material impacts related to foreign exchange fluctuations, macroeconomic activity including inflation, and industry-specific challenges including changes to government healthcare policy, among others.

For 2012, at current exchange rates(15), Pfizer is targeting reported revenues between $65.2 and $67.7 billion, reported diluted EPS(2) between $1.58 and $1.73, adjusted diluted EPS(1) between $2.25 and $2.35, adjusted R&D expenses(1) between $8.0 and $8.5 billion, adjusted operating margin(1) in a range of the high 30%s to low 40%s and adjusted other (income)/deductions(1) between $1.0 and $1.2 billion in deductions. The effective tax rate on adjusted income(1) is targeted at approximately 30%, while operating cash flow is expected to be at least $19.0 billion.
 
 
- 7 -

 
 
Additionally, the Company remains on-track to achieve the cost-reduction target of approximately $4 to $5 billion, by the end of 2012, at 2008 average foreign exchange rates, in comparison with the 2008 pro-forma adjusted total costs(14) of the legacy Pfizer and legacy Wyeth operations.

For additional details, please see the attached financial schedules, product revenue tables, supplemental information and disclosure notice.

(1)
"Adjusted Income" and its components and "Adjusted Diluted Earnings Per Share (EPS)" are defined as reported net income(2) and its components and reported diluted EPS(2) excluding purchase accounting adjustments, acquisition-related costs, discontinued operations and certain significant items.  Adjusted Cost of Sales, Adjusted SI&A expenses, Adjusted R&D expenses and Adjusted Other (Income)/Deductions are income statement line items prepared on the same basis, and therefore, components of the overall adjusted income measure.  As described under Adjusted Income in the Management’s Discussion and Analysis of Financial Condition and Results of Operations section of Pfizer's Form 10-Q for the fiscal quarter ended July 4, 2010, management uses adjusted income, among other factors, to set performance goals and to measure the performance of the overall company.  We believe that investors' understanding of our performance is enhanced by disclosing this measure. Reconciliations of third-quarter 2010 and 2009 and the first nine months of 2010 and 2009 adjusted income and its components and adjusted diluted EPS to reported net income(2) and its components and reported diluted EPS(2), as well as reconciliations of full-year 2010 guidance and 2012 targets for adjusted income and adjusted diluted EPS to full-year 2010 guidance and 2012 targets for reported net income(2) and reported diluted EPS(2), are provided in the materials accompanying this report. The adjusted income and its components and adjusted diluted EPS measures are not, and should not be viewed as, substitutes for U.S. generally accepted accounting principles (GAAP) net income and its components and diluted EPS.

(2)
“Reported Net Income” is defined as net income attributable to Pfizer Inc. in accordance with U.S. generally accepted accounting principles. Reported Diluted EPSis defined as reported diluted EPS attributable to Pfizer Inc. common shareholders in accordance with U.S. GAAP.

(3)
The Primary Care unit includes revenues from human pharmaceutical products primarily prescribed by primary-care physicians, and may include, but are not limited to, products in the following therapeutic and disease areas: Alzheimer’s disease, anxiety, cardiovascular (excluding pulmonary arterial hypertension), diabetes, pain, genitourinary, obesity, osteoporosis and respiratory.  Examples of products in this unit include, but are not limited to, Celebrex, Lipitor, Lyrica, Premarin, Pristiq and Viagra.  All revenues for such products are allocated to the Primary Care unit, except those generated in emerging markets(6) and those that are managed by the Established Products(5) unit.

 
- 8 -

 
 
(4)
The Specialty Care unit includes revenues from human pharmaceutical products primarily prescribed by physicians who are specialists, and may include, but are not limited to, products in the following therapeutic and disease areas: antibacterials, antifungals, antivirals, bone, inflammation, gastrointestinal, growth hormones, multiple sclerosis, ophthalmology, pulmonary arterial hypertension and psychosis.  Examples of products in this unit include, but are not limited to, Enbrel, Genotropin, Geodon, the Prevnar/Prevenar franchise, Xalatan and Zyvox.  All revenues for such products are allocated to the Specialty Care unit, except those generated in emerging markets(6) and those that are managed by the Established Products(5) unit.

(5)
The Established Products unit generally includes revenues from human prescription pharmaceutical products that have lost patent protection or marketing exclusivity in certain countries and/or regions. In certain situations, products may be transferred to this unit before losing patent protection or marketing exclusivity in order to maximize their value. This unit also excludes revenues generated in emerging markets(6). Examples of products in this unit include, but are not limited to, Arthrotec, Effexor, Medrol, Norvasc, Protonix, Relpax and Zosyn/Tazocin.
 
(6)
The Emerging Markets unit includes revenues from all human prescription pharmaceutical products sold in emerging markets, including, but not limited to, Asia (excluding Japan and South Korea), Latin America, Middle East, Africa, Central and Eastern Europe, Russia and Turkey.

(7)
The Oncology unit includes revenues from human oncology and oncology-related products.  Examples of products in this unit include, but are not limited to, Aromasin, Sutent and Torisel.  All revenues for such products are allocated to the Oncology unit, except those generated in emerging markets(6) and those that are managed by the Established Products(5) unit.

(8)
Animal Health includes worldwide revenues from products to prevent and treat disease in livestock and companion animals, including vaccines, paraciticides and anti-infectives.

(9)
Consumer Healthcare generally includes worldwide revenues from non-prescription medicines and vitamins and may include, but are not limited to, products in the following therapeutic categories: pain management, nutritionals, respiratory and GI-topicals.  Examples of products in Consumer Healthcare include, but are not limited to, Advil, Centrum, Caltrate, ChapStick and Robitussin.

(10)
Nutrition generally includes revenues from a full line of infant and toddler nutritional products sold outside of North America.  Examples of products in Nutrition include, but are not limited to, the S-26 and SMA product lines as well as formula for infants with special nutritional needs.

(11)
Capsugel generally includes worldwide revenues from capsule products and services for the pharmaceutical and associated healthcare industries.   On October 6, 2010, the Company announced that it is reviewing strategic alternatives for Capsugel, which may include a divestiture.

(12)
Includes revenues generated primarily from Pfizer Centersource.

(13)
In Biopharmaceutical, revenues from South Korea in 2009 have been reclassified from the Emerging Markets unit to the appropriate developed market units to conform to the current-year presentation, which reflects the fact that the commercial operations of South Korea, effective January 1, 2010, are managed within the appropriate developed market units.

 
- 9 -

 
 
(14)
Represents the total of Adjusted Cost of Sales(1), Adjusted SI&A expenses(1) and Adjusted R&D expenses(1).

(15)
The current exchange rates assumed in connection with the 2010 financial guidance are a blend of the average of the actual exchange rates in effect from December 2009 through September 2010 and the mid-October 2010 exchange rates for the remainder of the year.  The current exchanges rates assumed in connection with the 2012 financial targets are the mid-October 2010 exchange rates.

(16)
This guidance does not assume the completion of any business-development transactions not completed as of October 3, 2010, with the exception of the Biocon transaction.  This guidance also excludes the potential effects of the resolution of litigation-related matters not substantially resolved as of October 3, 2010.

 
Contacts:
           
Media
     
Investors
   
Joan Campion
 
212.733.2798
 
Suzanne Harnett
 
212.733.8009
 
  
 
  
Jennifer Davis
  
212.733.0717
 
 
- 10 -

 
 
PFIZER INC. AND SUBSIDIARY COMPANIES
CONSOLIDATED STATEMENTS OF INCOME
(UNAUDITED)
(millions, except per common share data)

   
Third Quarter
   
% Incr. /
   
Nine Months
   
% Incr. /
 
   
2010
   
2009
   
(Decr.)
   
2010
   
2009
   
(Decr.)
 
Revenues
  $ 16,171     $ 11,621       39     $ 50,248     $ 33,472       50  
Costs and expenses:
                                               
Cost of sales (a)
    3,896       1,789       118       11,997       4,953       142  
Selling, informational and administrative expenses (a)
    4,633       3,282       41       13,876       9,508       46  
Research and development expenses (a)
    2,194       1,632       34       6,607       5,032       31  
Amortization of intangible assets
    1,156       594       95       3,972       1,755       126  
Acquisition-related in-process research and development charges
    -       -       -       74       20       270  
Restructuring charges and certain acquisition-related costs
    499       193       159       2,091       1,206       73  
Other deductions—net
    2,353       160       *       3,038       175       *  
Income from continuing operations before provision for taxes on income
    1,440       3,971       (64 )     8,593       10,823       (21 )
Provision for taxes on income
    564       1,092       (48 )     3,198       2,952       8  
Income from continuing operations
    876       2,879       (70 )     5,395       7,871       (31 )
Discontinued operations—net of tax
    (5 )     2       *       (4 )     6       *  
Net income before allocation to noncontrolling interests
    871       2,881       (70 )     5,391       7,877       (32 )
Less: Net income attributable to noncontrolling interests
    5       3       67       24       9       167  
Net income attributable to Pfizer Inc.
  $ 866     $ 2,878       (70 )   $ 5,367     $ 7,868       (32 )
                                                 
Earnings per share - basic:
                                               
Income from continuing operations attributable to Pfizer Inc. common shareholders
  $ 0.11     $ 0.43       (74 )   $ 0.67     $ 1.17       (43 )
Discontinued operations—net of tax
    -       -             -       -        
Net income attributable to Pfizer Inc. common shareholders
  $ 0.11     $ 0.43       (74 )   $ 0.67     $ 1.17       (43 )
                                                 
Earnings per share - diluted:
                                               
Income from continuing operations attributable to Pfizer Inc. common shareholders
  $ 0.11     $ 0.43       (74 )   $ 0.66     $ 1.16       (43 )
Discontinued operations—net of tax
    -       -             -       -        
Net income attributable to Pfizer Inc. common shareholders
  $ 0.11     $ 0.43       (74 )   $ 0.66     $ 1.16       (43 )
                                                 
Weighted-average shares used to calculate earnings per common share:
                                               
Basic
    8,027       6,730               8,045       6,727          
Diluted
    8,057       6,762               8,079       6,758          
(a)
Exclusive of amortization of intangible assets, except as discussed in footnote 3 below.
*
Calculation not meaningful.
Certain amounts and percentages may reflect rounding adjustments.

1.
The above financial statements present the three-month and nine-month periods ended October 3, 2010 and September 27, 2009.  Subsidiaries operating outside the United States are included for the three-month and nine-month periods ended August 29, 2010 and August 23, 2009. Wyeth's results are included in our consolidated financial statements commencing from the acquisition date of October 15, 2009, in accordance with Pfizer's domestic and international year-ends. Therefore, our results of operations for the three-month and nine-month periods ended September 27, 2009 do not include Wyeth's results of operations. Cost of sales for 2010 includes the significant impacts of purchase accounting adjustments associated with inventory acquired from Wyeth that was sold in 2010 as well as a write-off of certain Wyeth-related inventory. Amortization of intangible assetsfor 2010 includes the amortization of intangible assets acquired from Wyeth. Other deductions-net includes impairment charges related to certain intangible assets acquired as part of our acquisition of Wyeth. See Supplemental Information that accompanies these materials for additional details related to the impairment charges and inventory write-off recorded in the third quarter of 2010 that impacted Other deductions-net and Cost of sales.

2.
The financial results for the three-month and nine-month periods ended October 3, 2010, are not necessarily indicative of the results which could ultimately be achieved for the current year.

3.
Amortization expense related to acquired intangible assets that contribute to our ability to sell, manufacture, research, market and distribute our products is included in Amortization of intangible assetsas these intangible assets benefit multiple business functions. Amortization expense related to acquired intangible assets that are associated with a single function is included in Cost of sales, Selling, informational and administrative expensesor Research and development expenses,as appropriate.
 
 
 

 
 
PFIZER INC. AND SUBSIDIARY COMPANIES
RECONCILIATION OF REPORTED NET INCOME ATTRIBUTABLE TO PFIZER INC. AND ITS COMPONENTS
AND REPORTED DILUTED EPS ATTRIBUTABLE TO PFIZER INC. COMMON SHAREHOLDERS
TO ADJUSTED INCOME AND ITS COMPONENTS AND ADJUSTED DILUTED EPS (a)
(UNAUDITED)
(millions of dollars, except per common share data)

   
Quarter Ended October 3, 2010
 
         
Purchase
   
Acquisition-
         
Certain
       
         
Accounting
   
Related
   
Discontinued
   
Significant
       
   
Reported
   
Adjustments
   
Costs(2)
   
Operations
   
Items(3)
   
Adjusted
 
Revenues
  $ 16,171     $ -     $ -     $ -     $ (5 )   $ 16,166  
Costs and expenses:
                                               
Cost of sales (b)
    3,896       (487 )     (241 )     -       (209 )     2,959  
Selling, informational and administrative expenses (b)
    4,633       8       (28 )     -       2       4,615  
Research and development expenses (b)
    2,194       (8 )     (26 )     -       -       2,160  
Amortization of intangible assets
    1,156       (1,124 )     -       -       -       32  
Acquisition-related in-process research and development charges
    -       -       -       -       -       -  
Restructuring charges and certain acquisition-related costs
    499       -       (499 )     -       -       -  
Other (income)/deductions—net
    2,353       (14 )     -       -       (2,208 )     131  
Income from continuing operations before provision for taxes on income
    1,440       1,625       794       -       2,410       6,269  
Provision for taxes on income
    564       379       232       -       717       1,892  
Income from continuing operations
    876       1,246       562       -       1,693       4,377  
Discontinued operations—net of tax
    (5 )     -       -       5       -       -  
Net income before allocation to noncontrolling interests
    871       1,246       562       5       1,693       4,377  
Less: Net income attributable to noncontrolling interests
    5       -       -       -       -       5  
Net income attributable to Pfizer Inc.
  $ 866     $ 1,246     $ 562     $ 5     $ 1,693     $ 4,372  
Earnings per common share - diluted:
                                               
Income from continuing operations attributable to Pfizer Inc. common shareholders
  $ 0.11     $ 0.15     $ 0.07     $ -     $ 0.21     $ 0.54  
Discontinued operations—net of tax
    -       -       -       -       -       -  
Net income attributable to Pfizer Inc. common shareholders
  $ 0.11     $ 0.15     $ 0.07     $ -     $ 0.21     $ 0.54  

   
Nine Months Ended October 3, 2010
 
         
Purchase
   
Acquisition-
         
Certain
       
         
Accounting
   
Related
   
Discontinued
   
Significant
       
   
Reported
   
Adjustments
   
Costs(2)
   
Operations
   
Items(3)
   
Adjusted
 
Revenues
  $ 50,248     $ -     $ -     $ -     $ (18 )   $ 50,230  
Costs and expenses:
                                               
Cost of sales (b)
    11,997       (2,564 )     (367 )     -       (221 )     8,845  
Selling, informational and administrative expenses (b)
    13,876       17       (190 )     -       14       13,717  
Research and development expenses (b)
    6,607       (23 )     (46 )     -       -       6,538  
Amortization of intangible assets
    3,972       (3,880 )     -       -       -       92  
Acquisition-related in-process research and development charges
    74       (74 )     -       -       -       -  
Restructuring charges and certain acquisition-related costs
    2,091       -       (2,091 )     -       -       -  
Other (income)/deductions—net
    3,038       (40 )     -       -       (2,500 )     498  
Income from continuing operations before provision for taxes on income
    8,593       6,564       2,694       -       2,689       20,540  
Provision for taxes on income
    3,198       1,631       695       -       779       6,303  
Income from continuing operations
    5,395       4,933       1,999       -       1,910       14,237  
Discontinued operations—net of tax
    (4 )     -       -       4       -       -  
Net income before allocation to noncontrolling interests
    5,391       4,933       1,999       4       1,910       14,237  
Less: Net income attributable to noncontrolling interests
    24       -       -       -       -       24  
Net income attributable to Pfizer Inc.
  $ 5,367     $ 4,933     $ 1,999     $ 4     $ 1,910     $ 14,213  
Earnings per common share - diluted:
                                               
Income from continuing operations attributable to Pfizer Inc. common shareholders
  $ 0.66     $ 0.61     $ 0.25     $ -     $ 0.24     $ 1.76  
Discontinued operations—net of tax
    -       -       -       -       -       -  
Net income attributable to Pfizer Inc. common shareholders
  $ 0.66     $ 0.61     $ 0.25     $ -     $ 0.24     $ 1.76  

(a)
Adjusted income and its components and adjusted diluted EPS are not, and should not be viewed as, substitutes for U.S. GAAP net income and its components and diluted EPS.
(b)
Exclusive of amortization of intangible assets, except as discussed in note 1.

See end of tables for notes.
Certain amounts may reflect rounding adjustments.
 
 

 
 
PFIZER INC. AND SUBSIDIARY COMPANIES
RECONCILIATION OF REPORTED NET INCOME ATTRIBUTABLE TO PFIZER INC. AND ITS COMPONENTS
AND REPORTED DILUTED EPS ATTRIBUTABLE TO PFIZER INC. COMMON SHAREHOLDERS
TO ADJUSTED INCOME AND ITS COMPONENTS AND ADJUSTED DILUTED EPS (a)
(UNAUDITED)
(millions of dollars, except per common share data)

   
Quarter Ended September 27, 2009
 
         
Purchase
   
Acquisition-
         
Certain
       
         
Accounting
   
Related
   
Discontinued
   
Significant
       
   
Reported
   
Adjustments
   
Costs(2)
   
Operations
   
Items(3)
   
Adjusted
 
Revenues
  $ 11,621     $ -     $ -     $ -     $ (18 )   $ 11,603  
Costs and expenses:
                                               
Cost of sales (b)
    1,789       -       -       -       (2 )     1,787  
Selling, informational and administrative expenses (b)
    3,282       3       -       -       (60 )     3,225  
Research and development expenses (b)
    1,632       (8 )     -       -       (5 )     1,619  
Amortization of intangible assets
    594       (560 )     -       -       -       34  
Acquisition-related in-process research and development charges
    -       -       -       -       -       -  
Restructuring charges and certain acquisition-related costs
    193       -       (132 )     -       (61 )     -  
Other (income)/deductions—net
    160       1       -       -       (303 )     (142 )
Income from continuing operations before provision for taxes on income
    3,971       564       132       -       413       5,080  
Provision for taxes on income
    1,092       167       45       -       312       1,616  
Income from continuing operations
    2,879       397       87       -       101       3,464  
Discontinued operations—net of tax
    2       -       -       (2 )     -       -  
Net income before allocation to noncontrolling interests
    2,881       397       87       (2 )     101       3,464  
Less: Net income attributable to noncontrolling interests
    3       -       -       -       -       3  
Net income attributable to Pfizer Inc.
  $ 2,878     $ 397     $ 87     $ (2 )   $ 101     $ 3,461  
Earnings per common share - diluted:
                                               
Income from continuing operations attributable to Pfizer Inc. common shareholders
  $ 0.43     $ 0.06     $ 0.01     $ -     $ 0.01     $ 0.51  
Discontinued operations—net of tax
    -       -       -       -       -       -  
Net income attributable to Pfizer Inc. common shareholders
  $ 0.43     $ 0.06     $ 0.01     $ -     $ 0.01     $ 0.51  

   
Nine Months Ended September 27, 2009
 
         
Purchase
   
Acquisition-
         
Certain
       
         
Accounting
   
Related
   
Discontinued
   
Significant
       
   
Reported
   
Adjustments
   
Costs(2)
   
Operations
   
Items(3)
   
Adjusted
 
Revenues
  $ 33,472     $ -     $ -     $ -     $ (58 )   $ 33,414  
Costs and expenses:
                                               
Cost of sales (b)
    4,953       -       -       -       (166 )     4,787  
Selling, informational and administrative expenses (b)
    9,508       9       -       -       (195 )     9,322  
Research and development expenses (b)
    5,032       (22 )     -       -       (70 )     4,940  
Amortization of intangible assets
    1,755       (1,656 )     -       -       -       99  
Acquisition-related in-process research and development charges
    20       (20 )     -       -       -       -  
Restructuring charges and certain acquisition-related costs
    1,206       -       (814 )     -       (392 )     -  
Other (income)/deductions—net
    175       (2 )     -       -       (731 )     (558 )
Income from continuing operations before provision for taxes on income
    10,823       1,691       814       -       1,496       14,824  
Provision for taxes on income
    2,952       524       290       -       672       4,438  
Income from continuing operations
    7,871       1,167       524       -       824       10,386  
Discontinued operations—net of tax
    6       -       -       (6 )     -       -  
Net income before allocation to noncontrolling interests
    7,877       1,167       524       (6 )     824       10,386  
Less: Net income attributable to noncontrolling interests
    9       -       -       -       -       9  
Net income attributable to Pfizer Inc.
  $ 7,868     $ 1,167     $ 524     $ (6 )   $ 824     $ 10,377  
Earnings per common share - diluted:
                                               
Income from continuing operations attributable to Pfizer Inc. common shareholders
  $ 1.16     $ 0.17     $ 0.08     $ -     $ 0.13     $ 1.54  
Discontinued operations—net of tax
    -       -       -       -       -       -  
Net income attributable to Pfizer Inc. common shareholders
  $ 1.16     $ 0.17     $ 0.08     $ -     $ 0.13     $ 1.54  

(a)
Adjusted income and its components and adjusted diluted EPS are not, and should not be viewed as, substitutes for U.S. GAAP net income and its components and diluted EPS.
(b)
Exclusive of amortization of intangible assets, except as discussed in note 1.

See end of tables for notes.
Certain amounts may reflect rounding adjustments.
 
 
 

 
 
PFIZER INC. AND SUBSIDIARY COMPANIES
RECONCILIATION OF REPORTED NET INCOME ATTRIBUTABLE TO PFIZER INC. AND ITS COMPONENTS
AND REPORTED DILUTED EPS ATTRIBUTABLE TO PFIZER INC. COMMON SHAREHOLDERS
TO ADJUSTED INCOME AND ITS COMPONENTS AND ADJUSTED DILUTED EPS*
(UNAUDITED)

1)
Amortization expense related to acquired intangible assets that contribute to our ability to sell, manufacture, research, market and distribute our products is included in Amortization of intangible assets as these intangible assets benefit multiple business functions. Amortization expense related to acquired intangible assets that are associated with a single function is included in Cost of sales, Selling, informational and administrative expensesor Research and development expenses,as appropriate.

2)
Acquisition-related costs includes the following:
 
     
Third Quarter
     
Nine Months
 
(millions of dollars)    
   
2010
     
2009
     
2010
     
2009
 
                                 
Transaction costs(a)
  $   -     $   19     $   13     $   572  
Integration costs(a)
      231         113         650         242  
Restructuring charges(a)
      268         -         1,428         -  
Additional depreciation - asset restructuring(b)
      295         -         603         -  
Total acquisition-related costs — pre-tax
      794         132         2,694         814  
Income taxes(c)
      (232 )       (45 )       (695 )       (290 )
Total acquisition-related costs — net of tax
  $   562     $   87     $   1,999     $   524  

 
(a)
Transaction costs include costs directly related to our acquisition of Wyeth, such as banking, legal, accounting and other similar costs. Integration costs represent external, incremental costs directly related to integrating Wyeth and primarily include expenditures for consulting and systems integration. Restructuring charges relate to our acquisition of Wyeth and include employee termination costs, asset impairments and exit costs.

 
(b)
Represents the impact of changes in the estimated useful lives of assets involved in restructuring actions related to our acquisition of Wyeth. Included in Cost of Sales ($241 million), Selling, informational and administrative expenses ($28 million), and Research and development expenses ($26 million) for the three months ended October 3, 2010. Included in Cost of sales ($367 million), Selling, informational and administrative expenses ($190 million) and Research and development expenses ($46 million) for the nine months ended October 3, 2010.

 
(c)
Included in Provision for taxes on income.

3)
Certain significant items includes the following:

   
Third Quarter
   
Nine Months
 
(millions of dollars)
 
2010
   
2009
   
2010
   
2009
 
                         
Restructuring charges - Cost-reduction initiatives(a)
  $ -     $ 61     $ -     $ 392  
Implementation costs - Cost-reduction initiatives(b)
    -       80       -       410  
Certain legal matters(c)
    701       40       843       170  
Net interest expense(d)
    -       299       -       528  
Certain asset impairment charges(e)
    1,468       -       1,668       66  
Inventory write-off(f)
    212       -       212       -  
Other(g)
    29       (67 )     (34 )     (70 )
Total certain significant items — pre-tax
    2,410       413       2,689       1,496  
Income taxes(h)
    (717 )     (312 )     (779 )     (672 )
Total certain significant items — net of tax
  $ 1,693     $ 101     $ 1,910     $ 824  

 
(a)
Included in Restructuring charges and certain acquisition-related costs.

 
(b)
Included in Cost of sales ($23 million), Selling, informational and administrative expenses ($51 million), Research and development expenses ($5 million), and Other deductions - net ($1 million) for the three months ended September 27, 2009. Included in Cost of sales ($144 million), Selling, informational and administrative expenses ($182 million), Research and development expenses ($78 million), and Other deductions - net ($6 million) for the nine months ended September 27, 2009.

 
(c)
Included in Other deductions - net.  The three-month and nine-month periods ended October 3, 2010 include an additional $701 million charge for asbestos litigation related to our wholly owned subsidiary, Quigley Company, Inc.

 
(d)
Included in Other deductions - net. Includes interest expense on the senior unsecured notes issued in connection with our acquisition of Wyeth less interest income earned on the proceeds of those notes.

 
(e)
Included in Other deductions - net. Amounts in 2010 represent impairment charges related to certain intangible assets acquired as part of our acquisition of Wyeth (see Supplemental Information that accompanies these materials).

 
(f)
Included in Cost of sales (see Supplemental Information that accompanies these materials).

 
(g)
Primarily included in Other deductions - net.  Amounts in the nine-month period of 2010 include the gain on the sale of certain Pfizer Animal Health products. expensesor Research and development expenses, as appropriate.

 
(h)
Included in Provision for taxes on income.  The three-month and nine-month periods ended September 27, 2009 include a tax benefit of approximately $174 million related to the final resolution of a previously disclosed settlement that resulted in the receipt of information that raised our assessment of the likelihood of prevailing on the technical merits of our tax position.

*
Adjusted income and its components and adjusted diluted EPS are not, and should not be viewed as, substitutes for U.S. GAAP net income and its components and diluted EPS.
 
 

 
 
PFIZER INC.
BUSINESS REVENUES(1),(2)
FIRST NINE MONTHS OF 2010 and 2009
(UNAUDITED)
(millions of dollars)

                           
Operational
 
   
2010
   
2009(2)
   
% Change
   
% Foreign
Exchange
   
Total %
   
Legacy Pfizer
%
 
Primary Care
  $ 17,442     $ 16,040       9       2       7       -  
Specialty Care
    11,009       4,465       147       2       145       1  
Established Products
    7,682       4,986       54       3       51       (11 )
Emerging Markets
    6,294       4,270       47       7       40       6  
Oncology
    1,045       1,081       (3 )     1       (4 )     (14 )
Biopharmaceutical
    43,472       30,842       41       3       38       (1 )
                                                 
Animal Health
    2,599       1,863       40       5       35       7  
Consumer Healthcare
    2,014       -       *       *       *       *  
Nutrition
    1,375       -       *       *       *       *  
Capsugel
    545       516       6       1       5       5  
Diversified
    6,533       2,379       175       9       166       7  
                                                 
Other
    243       251       (3 )     6       (9 )     (9 )
                                                 
TOTAL
  $ 50,248     $ 33,472       50       3       47       (1 )

* Calculation not meaningful

(1)
See notes 3-12 in the accompanying earnings release for a description of each business unit and of "Other".

(2)
In Biopharmaceutical, revenues from South Korea in 2009 have been reclassified from the Emerging Markets unit to the appropriate developed market units to conform to the current-year presentation, which reflects the fact that the commercial operations of South Korea, effective January 1, 2010, are managed within the appropriate developed market units.
 

PFIZER INC.
REVENUES
THIRD QUARTER 2010 and 2009
(UNAUDITED)
(millions of dollars)

   
WORLDWIDE
   
UNITED STATES
   
TOTAL INTERNATIONAL(1)
 
               
% Change
               
% Change
               
% Change
 
   
2010
   
2009
   
Total
   
Oper.
   
2010
   
2009
   
Total
   
2010
   
2009
   
Total
   
Oper.
 
TOTAL REVENUES
  $ 16,171     $ 11,621       39 %     40 %   $ 7,112     $ 4,816       48 %   $ 9,059     $ 6,805       33 %     35 %
TOTAL BIOPHARMACEUTICAL:
  $ 13,945     $ 10,677       31 %     33 %   $ 6,298     $ 4,448       42 %   $ 7,647     $ 6,229       23 %     26 %
Lipitor
    2,534       2,853       (11 %)     (10 %)     1,298       1,379       (6 %)     1,236       1,474       (16 %)     (14 %)
Enbrel (Outside the U.S. and Canada)***
    799       -       *       *       -       -       -       799       -       *       *  
Lyrica
    757       708       7 %     10 %     356       352       1 %     401       356       13 %     19 %
Celebrex
    578       602       (4 %)     (5 %)     390       421       (7 %)     188       181       4 %     1 %
Prevnar / Prevenar 13***
    735       -       *       *       540       -       *       195       -       *       *  
Effexor***
    175       -       *       *       58       -       *       117       -       *       *  
Viagra
    459       466       (2 %)     -       242       232       4 %     217       234       (7 %)     (5 %)
Xalatan / Xalacom
    416       436       (5 %)     (3 %)     157       143       10 %     259       293       (12 %)     (9 %)
Norvasc
    330       488       (32 %)     (35 %)     -       14       *       330       474       (30 %)     (32 %)
Prevnar / Prevenar 7***
    179       -       *       *       -       -       -       179       -       *       *  
Zyvox
    285       271       5 %     6 %     148       146       1 %     137       125       10 %     12 %
Premarin Family***
    263       -       *       *       241       -       *       22       -       *       *  
Sutent
    257       246       4 %     9 %     67       69       (3 %)     190       177       7 %     12 %
Geodon / Zeldox
    262       252       4 %     4 %     224       210       7 %     38       42       (10 %)     (9 %)
Detrol / Detrol LA
    237       283       (16 %)     (16 %)     163       197       (17 %)     74       86       (14 %)     (12 %)
Zosyn / Tazocin***
    255       -       *       *       177       -       *       78       -       *       *  
Genotropin
    211       232       (9 %)     (6 %)     51       56       (9 %)     160       176       (9 %)     (6 %)
Vfend
    200       196       2 %     5 %     64       61       5 %     136       135       1 %     4 %
Protonix***
    203       -       *       *       203       -       *       -       -       -       -  
Chantix / Champix
    163       155       5 %     5 %     74       75       (1 %)     89       80       11 %     11 %
Benefix***
    156       -       *       *       67       -       *       89       -       *       *  
Zoloft
    126       128       (2 %)     (3 %)     18       19       (5 %)     108       109       (1 %)     (3 %)
Caduet
    127       130       (2 %)     (3 %)     86       91       (5 %)     41       39       5 %     5 %
Aromasin
    111       123       (10 %)     (6 %)     39       40       (3 %)     72       83       (13 %)     (6 %)
Revatio
    116       111       5 %     7 %     72       71       1 %     44       40       10 %     15 %
Pristiq***
    118       -       *       *       102       -       *       16       -       *       *  
Medrol
    119       106       12 %     13 %     33       29       14 %     86       77       12 %     13 %
Cardura
    95       109       (13 %)     (11 %)     1       1       -       94       108       (13 %)     (11 %)
Aricept**
    100       108       (7 %)     (5 %)     -       -       -       100       108       (7 %)     (5 %)
Zithromax / Zmax
    90       85       6 %     4 %     4       2       100 %     86       83       4 %     2 %
BMP2***
    101       -       *       *       98       -       *       3       -       *       *  
Rapamune***
    104       -       *       *       55       -       *       49       -       *       *  
Refacto AF/Xyntha***
    102       -       *       *       22       -       *       80       -       *       *  
Fragmin
    84       82       2 %     5 %     13       14       (7 %)     71       68       4 %     6 %
Tygacil***
    78       -       *       *       40       -       *       38       -       *       *  
Alliance Revenue****
    1,042       692       51 %     51 %     741       422       76 %     301       270       11 %     12 %
All Other Biopharmaceutical
    1,978       1,815       9 %     11 %     454       404       12 %     1,524       1,411       8 %     9 %
All Other Established Products
    1,680       1,502       12 %     13 %     377       361       4 %     1,303       1,141       14 %     15 %
Legacy Pfizer Other Established Products
    1,452       1,502       (3 %)     (3 %)     368       361       2 %     1,084       1,141       (5 %)     (4 %)
TOTAL DIVERSIFIED:
  $ 2,150     $ 855       151 %     151 %   $ 792     $ 347       128 %   $ 1,358     $ 508       167 %     168 %
ANIMAL HEALTH***
    860       678       27 %     28 %     369       294       26 %     491       384       28 %     29 %
CONSUMER HEALTHCARE***
    673       -       *       *       374       -       *       299       -       *       *  
NUTRITION***
    441       -       *       *       -       -       -       441       -       *       *  
CAPSUGEL
    176       177       (1 %)     2 %     49       53       (8 %)     127       124       2 %     7 %
OTHER*****
  $ 76     $ 89       (15 %)     (31 %)   $ 22     $ 21       5 %   $ 54     $ 68       (21 %)     (18 %)

*
-  Calculation not meaningful.
**
-  Includes direct sales under license agreement with Eisai Co., Ltd.
***
-  Legacy Wyeth products and operations. Animal Health results for the third quarter of 2010 also reflect the addition of legacy Wyeth products. Wyeth's results are included in our financial statements commencing from the acquisition date of October 15, 2009, in accordance with Pfizer's domestic and international year-ends. Therefore, our results for the third quarter of 2009 do not include Wyeth's results of operations.
****
-  Enbrel (in the U.S. and Canada)***, Aricept, Rebif, and Exforge.
*****
-  Includes revenues generated primarily from Pfizer Centresource.
Certain amounts and percentages may reflect rounding adjustments.
 
(1)
Total International represents Developed Europe region + Developed Rest of World region + Emerging Markets region. Details for these regions are located on the following page.

 
 

 

PFIZER INC.
REVENUES
DETAIL OF INTERNATIONAL REVENUES BY GEOGRAPHIC REGION
THIRD QUARTER 2010 and 2009
(UNAUDITED)
(millions of dollars)

   
DEVELOPED EUROPE(1)
   
DEVELOPED REST OF WORLD(2)
   
EMERGING MARKETS(3)
 
               
% Change
               
% Change
               
% Change
 
   
2010
   
2009
   
Total
   
Oper.
   
2010
   
2009
   
Total
   
Oper.
   
2010
   
2009
   
Total
   
Oper.
 
TOTAL INTERNATIONAL REVENUES
  $ 3,840     $ 3,137       22 %     35 %   $ 2,377     $ 1,958       21 %     12 %   $ 2,842     $ 1,710       66 %     64 %
TOTAL INTERNATIONAL BIOPHARMACEUTICAL:
  $ 3,466     $ 2,853       21 %     34 %   $ 2,109     $ 1,847       14 %     6 %   $ 2,072     $ 1,529       36 %     34 %
Lipitor
    628       752       (16 %)     (8 %)     397       512       (22 %)     (28 %)     211       210       -       (2 %)
Enbrel (Outside the U.S. and Canada)***
    531       -       *       *       97       -       *       *       171       -       *       *  
Lyrica
    268       256       5 %     16 %     63       42       50 %     40 %     70       58       21 %     17 %
Celebrex
    42       53       (21 %)     (13 %)     86       64       34 %     22 %     60       64       (6 %)     (6 %)
Prevnar / Prevenar 13***
    129       -       *       *       21       -       *       *       45       -       *       *  
Effexor***
    55       -       *       *       37       -       *       *       25       -       *       *  
Viagra
    95       109       (13 %)     (5 %)     47       42       12 %     5 %     75       83       (10 %)     (11 %)
Xalatan / Xalacom
    134       155       (14 %)     (5 %)     81       92       (12 %)     (18 %)     44       46       (4 %)     (6 %)
Norvasc
    45       58       (22 %)     (12 %)     178       311       (43 %)     (47 %)     107       105       2 %     2 %
Prevnar / Prevenar 7***
    23       -       *       *       56       -       *       *       100       -       *       *  
Zyvox
    69       71       (3 %)     6 %     32       27       19 %     7 %     36       27       33 %     30 %
Premarin Family***
    3       -       *       *       7       -       *       *       12       -       *       *  
Sutent
    104       108       (4 %)     6 %     36       27       33 %     27 %     50       42       19 %     19 %
Geodon / Zeldox
    19       25       (24 %)     (16 %)     5       3       67 %     -       14       14       -       -  
Detrol / Detrol LA
    39       50       (22 %)     (18 %)     22       22       -       -       13       14       (7 %)     (7 %)
Zosyn / Tazocin***
    22       -       *       *       5       -       *       *       51       -       *       *  
Genotropin
    90       100       (10 )%     -       42       45       (7 %)     (15 %)     28       31       (10 %)     (10 %)
Vfend
    70       75       (7 %)     3 %     30       28       7 %     4 %     36       32       13 %     13 %
Protonix***
    -       -       -       -       -       -       -       -       -       -       -       -  
Chantix / Champix
    35       38       (8 %)     3 %     46       32       44 %     31 %     8       10       (20 %)     (27 %)
Benefix***
    62       -       *       *       24       -       *       *       3       -       *       *  
Zoloft
    21       24       (13 %)     (8 %)     57       54       6 %     -       30       31       (3 %)     (3 %)
Caduet
    5       6       (17 %)     (17 %)     22       21       5 %     5 %     14       12       17 %     17 %
Aromasin
    44       55       (20 %)     (9 %)     15       14       7 %     -       13       14       (7 %)     (7 %)
Revatio
    30       31       (3 %)     10 %     8       4       100 %     60 %     6       5       20 %     -  
Pristiq***
    -       -       -       -       10       -       *       *       6       -       *       *  
Medrol
    22       27       (19 %)     (4 %)     12       11       9 %     (9 %)     52       39       33 %     33 %
Cardura
    36       43       (16 %)     (9 %)     36       42       (14 %)     (20 %)     22       23       (4 %)     -  
Aricept**
    53       65       (18 %)     (11 %)     39       34       15 %     9 %     8       9       (11 %)     (10 %)
Zithromax / Zmax
    15       22       (32 %)     (19 %)     34       27       26 %     19 %     37       34       9 %     6 %
BMP2***
    3       -       *       *       -       -       -       -       -       -       -       -  
Rapamune***
    14       -       *       *       4       -       *       *       31       -       *       *  
Refacto AF/Xyntha***
    73       -       *       *       7       -       *       *       -       -       -       -  
Fragmin
    33       35       (6 %)     3 %     18       16       13 %     6 %     20       17       18 %     18 %
Tygacil***
    19       -       *       *       1       -       *       *       18       -       *       *  
Alliance Revenue****
    130       137       (5 %)     5 %     153       116       32 %     21 %     18       17       6 %     13 %
All Other Biopharmaceutical
    505       558       (9 %)     -       381       261       46 %     33 %     638       592       8 %     7 %
All Other Established Products
    390       376       4 %     14 %     329       223       48 %     37 %     584       542       8 %     7 %
Legacy Pfizer Other Established Products
    314       376       (16 %)     (8 %)     237       223       6 %     (1 %)     533       542       (2 %)     (3 %)
TOTAL INTERNATIONAL DIVERSIFIED:
  $ 336     $ 245       37 %     51 %   $ 260     $ 97       168 %     138 %   $ 762     $ 166       *       *  
OTHER INTERNATIONAL*****
  $ 38     $ 39       (3 %)     3 %   $ 8     $ 14       (43 %)     (38 %)   $ 8     $ 15       (47 %)     (50 %)

*
-  Calculation not meaningful.
**
-  Includes direct sales under license agreement with Eisai Co., Ltd.
***
-  Legacy Wyeth products and operations. Animal Health results for the third quarter of 2010 also reflect the addition of legacy Wyeth products. Wyeth's results are included in our financial statements commencing from the acquisition date of October 15, 2009, in accordance with Pfizer's domestic and international year-ends. Therefore, our results for the third quarter of 2009 do not do not include Wyeth's results of operations.
****
-  Enbrel (in the U.S. and Canada)***, Aricept, Rebif, and Exforge.
*****
-  Includes revenues generated primarily from Pfizer Centresource.
Certain amounts and percentages may reflect rounding adjustments.
 
(1)
Developed Europe region includes the following markets: Western Europe and the Scandinavian countries.
(2)
Developed Rest of World region includes the following markets:  Australia, Canada, Japan, New Zealand, and South Korea.
(3)
Emerging Markets region includes, but is not limited to, the following markets:  Asia (excluding Japan and South Korea), Latin America, Middle East, Africa, Central and Eastern Europe, Russia and Turkey. In Biopharmaceutical, revenues from South Korea in 2009 have been reclassified from the Emerging Markets unit to the appropriate developed market units to conform to the current-year presentation, which reflects the fact that the commercial operations of South Korea, effective January 1, 2010, are managed within the appropriate developed market units.

 
 

 

PFIZER INC.
REVENUES
FIRST NINE MONTHS OF 2010 and 2009
(UNAUDITED)
(millions of dollars)

   
WORLDWIDE
   
UNITED STATES
   
TOTAL INTERNATIONAL(1)
 
               
% Change
               
% Change
               
% Change
 
   
2010
   
2009
   
Total
   
Oper.
   
2010
   
2009
   
Total
   
2010
   
2009
   
Total
   
Oper.
 
TOTAL REVENUES
  $ 50,248     $ 33,472       50 %     47 %   $ 21,807     $ 14,309       52 %   $ 28,441     $ 19,163       48 %     42 %
TOTAL BIOPHARMACEUTICAL:
  $ 43,472     $ 30,842       41 %     38 %   $ 19,554     $ 13,347       47 %   $ 23,918     $ 17,495       37 %     31 %
Lipitor
    8,104       8,259       (2 %)     (5 %)     3,921       4,145       (5 %)     4,183       4,114       2 %     (4 %)
Enbrel (Outside the U.S. and Canada)***
    2,409       -       *       *       -       -       *       2,409       -       *       *  
Lyrica
    2,242       2,020       11 %     10 %     1,073       1,094       (2 %)     1,169       926       26 %     24 %
Celebrex
    1,752       1,714       2 %     -       1,176       1,230       (4 %)     576       484       19 %     11 %
Prevnar / Prevenar 13***
    1,590       -       *       *       1,231       -       *       359       -       *       *  
Effexor***
    1,512       -       *       *       1,142       -       *       370       -       *       *  
Viagra
    1,429       1,343       6 %     4 %     729       697       5 %     700       646       8 %     3 %
Xalatan / Xalacom
    1,287       1,238       4 %     2 %     453       414       9 %     834       824       1 %     (2 %)
Norvasc
    1,120       1,487       (25 %)     (28 %)     24       49       (51 %)     1,096       1,438       (24 %)     (27 %)
Prevnar / Prevenar 7***
    1,030       -       *       *       214       -       *       816       -       *       *  
Zyvox
    876       811       8 %     7 %     463       459       1 %     413       352       17 %     14 %
Premarin Family***
    779       -       *       *       713       -       *       66       -       *       *  
Sutent
    771       671       15 %     13 %     198       192       3 %     573       479       20 %     17 %
Geodon / Zeldox
    763       713       7 %     6 %     642       597       8 %     121       116       4 %     -  
Detrol / Detrol LA
    758       845       (10 %)     (12 %)     515       600       (14 %)     243       245       (1 %)     (5 %)
Zosyn / Tazocin***
    749       -       *       *       505       -       *       244       -       *       *  
Genotropin
    650       636       2 %     -       156       160       (3 %)     494       476       4 %     1 %
Vfend
    595       555       7 %     5 %     187       177       6 %     408       378       8 %     5 %
Protonix***
    535       -       *       *       535       -       *       -       -       -       -  
Chantix / Champix
    522       524       -       (4 %)     252       303       (17 %)     270       221       22 %     14 %
Benefix***
    474       -       *       *       211       -       *       263       -       *       *  
Zoloft
    390       368       6 %     2 %     54       62       (13 %)     336       306       10 %     5 %
Caduet
    388       392       (1 %)     (5 %)     256       294       (13 %)     132       98       35 %     20 %
Aromasin
    361       347       4 %     3 %     122       121       1 %     239       226       6 %     4 %
Revatio
    352       319       10 %     9 %     216       212       2 %     136       107       27 %     24 %
Pristiq***
    341       -       *       *       301       -       *       40       -       *       *  
Medrol
    341       334       2 %     1 %     88       105       (16 %)     253       229       10 %     8 %
Cardura
    312       330       (5 %)     (8 %)     11       4       175 %     301       326       (8 %)     (10 %)
Aricept**
    310       311       -       (6 %)     -       -       -       310       311       -       (6 %)
Zithromax / Zmax
    303       299       1 %     (2 %)     10       10       -       293       289       1 %     (2 %)
BMP2***
    298       -       *       *       286       -       *       12       -       *       *  
Rapamune***
    292       -       *       *       150       -       *       142       -       *       *  
Refacto AF/Xyntha***
    290       -       *       *       61       -       *       229       -       *       *  
Fragmin
    258       244       6 %     2 %     40       51       (22 %)     218       193       13 %     8 %
Tygacil***
    250       -       *       *       133       -       *       117       -       *       *  
Alliance Revenue****
    3,107       1,872       66 %     64 %     2,211       1,133       95 %     896       739       21 %     17 %
All Other Biopharmaceutical
    5,932       5,210       14 %     11 %     1,275       1,238       3 %     4,657       3,972       17 %     13 %
    All Other Established Products
    5,071       4,325       17 %     14 %     1,106       1,101       -       3,965       3,224       23 %     18 %
        Legacy Pfizer Other Established Products
    4,351       4,325       1 %     (2 %)     1,084       1,101       (2 %)     3,267       3,224       1 %     (3 %)
TOTAL DIVERSIFIED:
  $ 6,533     $ 2,379       175 %     166 %   $ 2,168     $ 901       141 %   $ 4,365     $ 1,478       195 %     181 %
ANIMAL HEALTH***
    2,599       1,863       40 %     35 %     1,006       749       34 %     1,593       1,114       43 %     35 %
CONSUMER HEALTHCARE***
    2,014       -       *       *       1,016       -       *       998       -       *       *  
NUTRITION***
    1,375       -       *       *       -       -       -       1,375       -       *       *  
CAPSUGEL
    545       516       6 %     5 %     146       152       (4 %)     399       364       10 %     9 %
OTHER*****
  $ 243     $ 251       (3 %)     (9 %)   $ 85     $ 61       39 %   $ 158     $ 190       (17 %)     (16 %)

*
-  Calculation not meaningful.
**
-  Includes direct sales under license agreement with Eisai Co., Ltd.
***
-  Legacy Wyeth products and operations. Animal Health results for the first nine months of 2010 also reflect the addition of legacy Wyeth products. Wyeth's results are included in our financial statements commencing from the acquisition date of October 15, 2009, in accordance with Pfizer's domestic and international year-ends. Therefore, our results for the first nine months of 2009 do not include Wyeth's results of operations.
****
-  Enbrel (in the U.S. and Canada)***, Aricept, Rebif, and Exforge.
*****
-  Includes revenues generated primarily from Pfizer Centresource.
Certain amounts and percentages may reflect rounding adjustments.
 
(1)
Total International represents Developed Europe region + Developed Rest of World region + Emerging Markets region. Details for these regions are located on the following page.

 
 

 

PFIZER INC.
REVENUES
DETAIL OF INTERNATIONAL REVENUES BY GEOGRAPHIC REGION
FIRST NINE MONTHS OF 2010 and 2009
(UNAUDITED)
(millions of dollars)

   
DEVELOPED EUROPE(1)
   
DEVELOPED REST OF WORLD(2)
   
EMERGING MARKETS(3)
 
               
% Change
               
% Change
               
% Change
 
   
2010
   
2009
   
Total
   
Oper.
   
2010
   
2009
   
Total
   
Oper.
   
2010
   
2009
   
Total
   
Oper.
 
TOTAL INTERNATIONAL REVENUES
  $ 12,313     $ 8,726       41 %     41 %   $ 7,401     $ 5,648       31 %     18 %   $ 8,727     $ 4,789       82 %     73 %
TOTAL INTERNATIONAL BIOPHARMACEUTICAL:
  $ 10,974     $ 7,892       39 %     39 %   $ 6,650     $ 5,333       25 %     13 %   $ 6,294     $ 4,270       47 %     40 %
Lipitor
    1,987       2,049       (3 %)     (3 %)     1,505       1,450       4 %     (10 %)     691       615       12 %     5 %
Enbrel (Outside the U.S. and Canada)***
    1,659       -       *       *       288       -       *       *       462       -       *       *  
Lyrica
    802       666       20 %     21 %     162       107       51 %     33 %     205       153       34 %     27 %
Celebrex
    132       142       (7 %)     (7 %)     245       170       44 %     29 %     199       172       16 %     9 %
Prevnar / Prevenar 13***
    274       -       *       *       23       -       *       *       62       -       *       *  
Effexor***
    184       -       *       *       113       -       *       *       73       -       *       *  
Viagra
    299       299       -       -       143       119       20 %     7 %     258       228       13 %     7 %
Xalatan / Xalacom
    430       424       1 %     2 %     265       272       (3 %)     (10 %)     139       128       9 %     2 %
Norvasc
    154       171       (10 %)     (9 %)     601       940       (36 %)     (40 %)     341       327       4 %     2 %
Prevnar / Prevenar 7***
    230       -       *       *       172       -       *       *       414       -       *       *  
Zyvox
    215       194       11 %     12 %     93       83       12 %     5 %     105       75       40 %     31 %
Premarin Family***
    8       -       *       *       21       -       *       *       37       -       *       *  
Sutent
    322       304       6 %     7 %     100       62       61 %     47 %     151       113       34 %     28 %
Geodon / Zeldox
    66       67       (1 %)     (1 %)     13       9       44 %     10 %     42       40       5 %     (5 %)
Detrol / Detrol LA
    129       143       (10 %)     (11 %)     71       62       15 %     3 %     43       40       8 %     3 %
Zosyn / Tazocin***
    83       -       *       *       12       -       *       *       149       -       *       *  
Genotropin
    277       266       4 %     4 %     133       131       2 %     (5 %)     84       79       6 %     -  
Vfend
    219       210       4 %     5 %     92       81       14 %     6 %     97       87       11 %     6 %
Protonix***
    -       -       -       -       -       -       -       -       -       -       -       -  
Chantix / Champix
    123       109       13 %     12 %     124       88       41 %     22 %     23       24       (4 %)     (8 %)
Benefix***
    187       -       *       *       65       -       *       *       11       -       *       *  
Zoloft
    66       69       (4 %)     (4 %)     181       151       20 %     13 %     89       86       3 %     -  
Caduet
    15       14       7 %     14 %     79       52       52 %     27 %     38       32       19 %     16 %
Aromasin
    146       148       (1 %)     (1 %)     45       40       13 %     5 %     48       38       26 %     21 %
Revatio
    94       81       16 %     16 %     24       14       71 %     53 %     18       12       50 %     33 %
Pristiq***
    -       -       *       *       27       -       *       *       13       -       *       *  
Medrol
    74       76       (3 %)     (1 %)     34       36       (6 %)     (14 %)     145       117       24 %     21 %
Cardura
    114       124       (8 %)     (8 %)     116       131       (11 %)     (15 %)     71       71       -       (3 %)
Aricept**
    172       190       (9 %)     (10 %)     111       90       23 %     7 %     27       31       (13 %)     (16 %)
Zithromax / Zmax
    61       86       (29 %)     (30 %)     115       103       12 %     6 %     117       100       17 %     13 %
BMP2***
    12       -       *       *       -       -       -       -       -       -       -       -  
Rapamune***
    41       -       *       *       13       -       *       *       88       -       *       *  
Refacto AF/Xyntha***
    209       -       *       *       20       -       *       *       -       -       -       -  
Fragmin
    110       97       13 %     11 %     48       41       17 %     2 %     60       55       9 %     5 %
Tygacil***.
    60       -       *       *       3       -       *       *       54       -       *       *  
Alliance Revenue****
    399       377       6 %     7 %     442       317       39 %     29 %     55       45       22 %     16 %
All Other Biopharmaceutical
    1,621       1,586       2 %     2 %     1,151       784       47 %     35 %     1,885       1,602       18 %     12 %
    All Other Established Products
    1,273       1,082       18 %     18 %     1,008       670       50 %     38 %     1,684       1,472       14 %     10 %
Legacy Pfizer Other Established Products
    1,030       1,082       (5 %)     (5 %)     706       670       5 %     (4 %)     1,531       1,472       4 %     -  
TOTAL INTERNATIONAL DIVERSIFIED:
  $ 1,238     $ 725       71 %     71 %   $ 728     $ 281       159 %     123 %   $ 2,399     $ 472       *       *  
OTHER INTERNATIONAL*****
  $ 101     $ 109       (7 %)     (7 %)   $ 23     $ 34       (32 %)     (24 %)   $ 34     $ 47       (28 %)     (30 %)

*
-  Calculation not meaningful.
**
-  Includes direct sales under license agreement with Eisai Co., Ltd.
***
-  Legacy Wyeth products and operations. Animal Health results for the first nine months of 2010 also reflect the addition of legacy Wyeth products. Wyeth's results are included in our financial statements commencing from the acquisition date of October 15, 2009, in accordance with Pfizer's domestic and international year-ends. Therefore, our results for the first nine months of 2009 do not include Wyeth's results of operations.
****
-  Enbrel (in the U.S. and Canada)***, Aricept, Rebif, and Exforge.
*****
-  Includes revenues generated primarily from Pfizer Centresource.
Certain amounts and percentages may reflect rounding adjustments.
 
(1)
Developed Europe region includes the following markets: Western Europe and the Scandinavian countries.
(2)
Developed Rest of World region includes the following markets:  Australia, Canada, Japan, New Zealand, and South Korea.
(3)
Emerging Markets region includes, but is not limited to, the following markets:  Asia (excluding Japan and South Korea), Latin America, Middle East, Africa, Central and Eastern Europe, Russia and Turkey. In Biopharmaceutical, revenues from South Korea in 2009 have been reclassified from the Emerging Markets unit to the appropriate developed market units to conform to the current-year presentation, which reflects the fact that the commercial operations of South Korea, effective January 1, 2010, are managed within the appropriate developed market units.

 
 

 
 
PFIZER INC.
SUPPLEMENTAL INFORMATION

1. Change in Reported Cost of Sales

Reported cost of sales increased 118% in the third quarter of 2010, compared to the same period in 2009, and increased 142% in the first nine months of 2010, compared to the same period in 2009. The increases primarily reflect purchase accounting adjustments associated with the Wyeth acquisition, a write-off of Wyeth-related inventory of $212 million (which includes a purchase accounting fair value adjustment of $104 million), the addition of Wyeth manufacturing costs, as well as the change in the mix of products and businesses as a result of the Wyeth acquisition, partially offset by a favorable impact of foreign exchange for both the third quarter and first nine months of 2010. The write-off of inventory primarily relates to unfinished inventory acquired from Wyeth that became unusable after the acquisition date.

Reported cost of sales as a percentage of revenues increased 8.7 percentage points to 24.1% in third-quarter 2010, compared to the same period in 2009, reflecting the aforementioned factors.

2. Change in Reported Selling, Informational & Administrative (SI&A) Expenses and Reported Research & Development (R&D) Expenses

Reported SI&A expenses increased 41% in the third quarter of 2010, compared to the same period in 2009, and increased 46% in the first nine months of 2010, compared to the same period in 2009. The increases primarily reflect the addition of Wyeth operating costs. Foreign exchange had a favorable impact on reported SI&A expenses in the third quarter of 2010 and an unfavorable impact for the first nine months of 2010.

Reported R&D expenses increased 34% in the third quarter of 2010, compared to the same period in 2009, and increased 31% in the first nine months of 2010, compared to the same period in 2009. The increases are primarily due to the addition of legacy Wyeth operations and continued investment in the late-stage development portfolio. Foreign exchange had a favorable impact on reported R&D expenses in the third quarter of 2010 and an unfavorable impact for the first nine months of 2010.

3. Other (Income)/Deductions - Net
  
($ in millions)
 
Third Quarter
   
Nine Months
 
   
2010
   
2009
   
2010
   
2009
 
Interest income(a)
  $ (100 )   $ (171 )   $ (297 )   $ (620 )
Interest expense(a)
    428       369       1,339       769  
Net interest expense
    328       198       1,042       149  
Royalty-related income
    (158 )     (35 )     (395 )     (142 )
Net gain on asset disposals
    (13 )     (40 )     (243 )     (81 )
Legal matters, net(b)
    712       54       886       130  
Certain asset impairment charges(c)
    1,478       6       1,710       96  
Other, net
    6       (23 )     38       23  
Other deductions-net
  $ 2,353     $ 160     $ 3,038     $ 175  
 
(a)
Interest expense increased in 2010 due to our issuance of $13.5 billion of senior unsecured notes on March 24, 2009 and $10.5 billion of senior unsecured notes on June 3, 2009, primarily related to the acquisition of Wyeth. Interest income decreased in 2010 due to lower interest rates coupled with lower average cash balances.
(b)
The three-month and nine-month periods ended October 3, 2010 include an additional $701 million charge for asbestos litigation related to our wholly owned subsidiary, Quigley Company, Inc.
(c)
Amounts in 2010 represent impairment charges related to intangible assets, including certain in-process research and development ("IPR&D") intangible assets, that were acquired in connection with our acquisition of Wyeth. These impairment charges primarily resulted from our current estimate of the fair value of these assets based upon updated forecasts of these Wyeth assets as compared to their assigned fair values at the closing of the Wyeth acquisition last year. Our updated forecasts are based on projected development and regulatory timeframes, and for brand assets and developed technology, the current market environment as well as planned investment support.

 
1

 
 
4. Effective Tax Rate

Reported
The effective tax rate on reported Income from continuing operations before provision for taxes on income for third-quarter 2010 was 39.2% compared to 27.5% in the third quarter of 2009, and in the first nine months of 2010 was 37.2% compared to 27.3% in the first nine months of 2009. The higher tax rates in the third quarter and first nine months of 2010 are primarily the result of:

 
·
higher expenses, incurred as a result of our acquisition of Wyeth, and the mix of jurisdictions in which those expenses were incurred;
 
·
the expiration of the U.S. research and development tax credit; and
 
·
the non-recurrence of a tax benefit of $174 million that was recorded in the third quarter of 2009 related to the final resolution of a previously disclosed settlement that resulted in the receipt of information that raised our assessment of the likelihood of prevailing on the technical merits of our tax position;

partially offset by:

 
·
the tax impact of the charge incurred for asbestos litigation.

The effective tax rate for the first nine months of 2010 was additionally impacted by the write-off of the deferred tax asset of approximately $270 million related to the Medicare Part D subsidy for retiree prescription drug coverage, resulting from changes in the U.S. healthcare legislation enacted in March 2010 concerning the tax treatment of that subsidy effective for tax years beginning after December 31, 2012, offset by $460 million in tax benefits for the resolution of certain tax positions pertaining to prior years with various foreign tax authorities.

Adjusted
The effective tax rate on adjusted income(1) decreased to 30.2% in third-quarter 2010 compared to 31.8% in third-quarter 2009, as a result of the change in the jurisdictional mix of earnings, partially offset by the expiration of the U.S. research and development tax credit.
 
The effective tax rate on adjusted income(1) for the first nine months of 2010 was 30.7% compared to 29.9% in the first nine months of 2009. In addition to the aforementioned factors, the effective tax rate on adjusted income(1) for the first nine months of 2010 was impacted by the write-off of the deferred tax asset of approximately $270 million related to the Medicare Part D subsidy for retiree prescription drug coverage, resulting from changes in the U.S. healthcare legislation enacted in March 2010 concerning the tax treatment of that subsidy effective for tax years beginning after December 31, 2012, offset by $460 million in tax benefits for the resolution of certain tax positions pertaining to prior years with various foreign tax authorities.
 
5. Reconciliation of 2010 Adjusted Income(1) and Adjusted Diluted EPS(1) Guidance to 2010 Reported Net Income Attributable to Pfizer Inc. and Reported Diluted EPS Attributable to Pfizer Inc. Common Shareholders Guidance (a)
 
   
Full-Year 2010 Guidance
 
($ in billions, except per share amounts)
 
Net Income(b)
   
Diluted EPS(b)
 
Income/(Expense)
           
Adjusted Income/Diluted EPS(1) Guidance
 
~$17.6 - $18.0
   
~$2.17 - $2.22
 
Purchase Accounting Impacts of Transactions Completed as of 10/3/10
    (6.1 )     (0.75 )
Acquisition-Related Costs
    (2.4 – 2.8 )     (0.29 – 0.34 )
Certain Significant Items
    (1.9 )     (0.24 )
Reported Net Income Attributable to Pfizer Inc./Diluted EPS Guidance
 
~$6.8 - $7.6
   
~$0.84 - $0.94
 
  
(a)
The current exchange rates assumed in connection with the 2010 financial guidance are a blend of the average of theactual exchange rates in effect from December 2009 through September 2010 and the mid-October 2010 exchange rates for the remainder of the year.
(b)
Does not assume the completion of any business-development transactions not completed as of October 3, 2010 with the exception of the Biocon transaction. Amounts exclude the potential effects of the resolution of litigation-related matters not substantially resolved as of October 3, 2010.

 
2

 
 
6. Reconciliation of 2012 Adjusted Income(1) and Adjusted Diluted EPS(1) Targets to 2012 Reported Net Income Attributable to Pfizer Inc. and Reported Diluted EPS Attributable to Pfizer Inc. Common Shareholders Targets (a)
 
   
Full-Year 2012 Targets
 
($ in billions, except per share amounts)
 
Net Income(b)
   
Diluted EPS(b)
 
Income/(Expense)
           
Adjusted Income/Diluted EPS(1) Targets
 
~$18.3 - $19.1
   
~$2.25 - $2.35
 
Purchase Accounting Impacts of Transactions Completed as of 10/3/10
    (3.8 )     (0.47 )
Acquisition-Related Costs
    (1.2 – 1.6 )     (0.15 – 0.20 )
Reported Net Income Attributable to Pfizer Inc./Diluted EPS Targets
 
~$12.9 - $14.1
   
~$1.58 - $1.73
 
 
(a) 
The current exchange rates assumed in connection with the 2012 financial targets are the mid-October 2010 exchange rates.
(b)
Given the longer-term nature of these targets, they are subject to greater variability and less certainty as aresult of potential material impacts related to foreign exchange fluctuations, macroeconomic activity including inflation, and industry-specific challenges including changes to government healthcare policy, among others. 
  

 
(1) “Adjusted income” and “adjusted diluted earnings per share (EPS)” are defined as reported net income attributable to Pfizer Inc. and reported diluted EPS attributable to Pfizer Inc. common shareholders excluding purchase accounting adjustments, acquisition-related costs, discontinued operations and certain significant items. As described under Adjusted Income in the Management’s Discussion and Analysis of Financial Condition and Results of Operations section of Pfizer’s Form 10-Q for the fiscal quarter ended July 4, 2010, management uses adjusted income, among other factors, to set performance goals and to measure the performance of the overall company. We believe that investors’ understanding of our performance is enhanced by disclosing this measure. The adjusted income and adjusted diluted EPS measures are not, and should not be viewed as, substitutes for U.S. GAAP net income and diluted EPS.

 
3

 
 
DISCLOSURE NOTICE: The information contained in this earnings release and the attachments is as of November 2, 2010. The Company assumes no obligation to update forward-looking statements contained in this earnings release or the attachments as a result of new information or future events or developments.
 
This earnings release and the attachments contain forward-looking information about the Company's financial results and estimates, business plans and prospects, in-line products and product candidates that involves substantial risks and uncertainties. You can identify these statements by the fact that they use words such as "will," "anticipate," "estimate," "expect," "project," "intend," "plan," "believe," "target," "forecast" and other words and terms of similar meaning in connection with any discussion of future operating or financial performance or business plans and prospects. Among the factors that could cause actual results to differ materially are the following: the success of research and development activities, including, without limitation, the ability to meet anticipated clinical trial completion dates and regulatory submission dates for product candidates; decisions by regulatory authorities regarding whether and when to approve our drug applications as well as their decisions regarding labeling, ingredients and other matters that could affect the availability or commercial potential of our products; the speed with which regulatory authorizations, pricing approvals and product launches may be achieved; the success of external business development activities; competitive developments, including the impact on our competitive position of new product entrants, in-line branded products, generic products, private label products and product candidates that treat diseases and conditions similar to those treated by our in-line drugs and drug candidates; the ability to meet generic and branded competition after the loss of patent protection for our products or competitor products; the ability to successfully market both new and existing products domestically and internationally; difficulties or delays in manufacturing; trade buying patterns; the impact of existing and future legislation and regulatory provisions on product exclusivity; trends toward managed care and healthcare cost containment; the impact of U.S. healthcare legislation enacted in 2010 – the Patient Protection and Affordable Care Act, as amended by the Health Care and Education Reconciliation Act; U.S. legislation or regulatory action affecting, among other things, pharmaceutical product pricing, reimbursement or access, including under Medicaid, Medicare and other publicly funded or subsidized health programs, the importation of prescription drugs from outside the U.S. at prices that are regulated by governments of various foreign countries, direct-to-consumer advertising and interactions with healthcare professionals, and the use of comparative effectiveness methodologies that could be implemented in a manner that focuses primarily on the cost differences and minimizes the therapeutic differences among pharmaceutical products and restricts access to innovative medicines; legislation or regulatory action in markets outside the U.S. affecting pharmaceutical product pricing, reimbursement or access; contingencies related to actual or alleged environmental contamination; claims and concerns that may arise regarding the safety or efficacy of in-line products and product candidates; significant breakdown, infiltration, or interruption of our information technology systems and infrastructure; legal defense costs, insurance expenses, settlement costs and the risk of an adverse decision or settlement related to product liability, patent protection, government investigations, consumer, commercial, securities, environmental and tax issues, ongoing efforts to explore various means for resolving asbestos litigation, and other legal proceedings; the Company's ability to protect its patents and other intellectual property both domestically and internationally; interest rate and foreign currency exchange rate fluctuations; governmental laws and regulations affecting domestic and foreign operations, including, without limitation, tax obligations and changes affecting the tax treatment by the U.S. of income earned outside of the U.S. that result from the enactment in August 2010 of the Education Jobs and Medicaid Assistance Act of 2010 and that may result from pending and possible future proposals; changes in U.S. generally accepted accounting principles; uncertainties related to general economic, political, business, industry, regulatory and market conditions including, without limitation, uncertainties related to the impact on us, our lenders, our customers, our suppliers and counterparties to our foreign exchange and interest rate agreements of weak global economic conditions and recent and possible future changes in global financial markets; any changes in business, political and economic conditions due to actual or threatened terrorist activity in the U.S. and other parts of the world, and related U.S. military action overseas; growth in costs and expenses; changes in our product, segment and geographic mix; and the impact of acquisitions, divestitures, restructurings, product withdrawals and other unusual items, including our ability to realize the projected benefits of our acquisition of Wyeth and of our cost-reduction initiatives. A further list and description of risks, uncertainties and other matters can be found in the Company's Annual Report on Form 10-K for the fiscal year ended December 31, 2009, and in its reports on Forms 10-Q and 8-K.
  
This earnings release may include discussion of certain clinical studies relating to various in-line products and/or product candidates.  These studies typically are part of a larger body of clinical data relating to such products or product candidates, and the discussion herein should be considered in the context of the larger body of data.