-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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MIC-Info: RSA-MD5,RSA,
 Fp5TxTzlwHVTOdClRZVp4UQ4uQZU4fs+JdmhDZ/BDdWbfVeNt2dPJHTbH0az5RWk
 la8V/Cg4u1zY8onH45FNrQ==

<SEC-DOCUMENT>0001140361-10-014971.txt : 20100402
<SEC-HEADER>0001140361-10-014971.hdr.sgml : 20100402
<ACCEPTANCE-DATETIME>20100402104725
ACCESSION NUMBER:		0001140361-10-014971
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20100402
FILED AS OF DATE:		20100402
DATE AS OF CHANGE:		20100402

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			PICKERING CHRISTINE L
		CENTRAL INDEX KEY:			0001250150

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-13089
		FILM NUMBER:		10726921

	MAIL ADDRESS:	
		STREET 1:		P O BOX 4019
		CITY:			GULFPORT
		STATE:			MS
		ZIP:			39502

	FORMER NAME:	
		FORMER CONFORMED NAME:	SMILEK CHRISTINE L
		DATE OF NAME CHANGE:	20030628

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			HANCOCK HOLDING CO
		CENTRAL INDEX KEY:			0000750577
		STANDARD INDUSTRIAL CLASSIFICATION:	STATE COMMERCIAL BANKS [6022]
		IRS NUMBER:				640693170
		STATE OF INCORPORATION:			MS
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		ONE HANCOCK PLZ
		STREET 2:		P.O. BOX 4019
		CITY:			GULFPORT
		STATE:			MS
		ZIP:			39501
		BUSINESS PHONE:		6018684605

	MAIL ADDRESS:	
		STREET 1:		ONE HANCOCK PLZ
		STREET 2:		P O BOX 4019
		CITY:			GULFPORT
		STATE:			MS
		ZIP:			39501
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>doc1.xml
<DESCRIPTION>FORM 4
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2010-04-02</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000750577</issuerCik>
        <issuerName>HANCOCK HOLDING CO</issuerName>
        <issuerTradingSymbol>HBHC</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001250150</rptOwnerCik>
            <rptOwnerName>PICKERING CHRISTINE L</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>P.O. BOX 4019</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>GULFPORT</rptOwnerCity>
            <rptOwnerState>MS</rptOwnerState>
            <rptOwnerZipCode>39502</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle></officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common</value>
            </securityTitle>
            <transactionDate>
                <value>2010-03-31</value>
            </transactionDate>
            <deemedExecutionDate>
                <value>2010-04-02</value>
            </deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>414</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>42.14</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>4972.533</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <derivativeTable></derivativeTable>

    <footnotes></footnotes>

    <remarks>Open market sale of common equity shares.</remarks>

    <ownerSignature>
        <signatureName>Christine L. Pickering by:  Paul D. Guichet (POA)</signatureName>
        <signatureDate>2010-04-02</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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