-----BEGIN PRIVACY-ENHANCED MESSAGE----- Proc-Type: 2001,MIC-CLEAR Originator-Name: webmaster@www.sec.gov Originator-Key-Asymmetric: MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB MIC-Info: RSA-MD5,RSA, GWEohBf0+Tlo8T3sDaLbXtLdgulz+2+suhjKi1g1AdNqjU/6tguQUWUuJJjl9QAG ZCBKjGBTuGkiHExGMrCYuQ== 0001144204-05-004203.txt : 20050211 0001144204-05-004203.hdr.sgml : 20050211 20050211171427 ACCESSION NUMBER: 0001144204-05-004203 CONFORMED SUBMISSION TYPE: SC 13G/A PUBLIC DOCUMENT COUNT: 1 FILED AS OF DATE: 20050211 DATE AS OF CHANGE: 20050211 GROUP MEMBERS: ABINGTON BIOMEDICAL MASTER FUND, LTD. GROUP MEMBERS: ARIES DOMESTIC FUND II, LP GROUP MEMBERS: ARIES DOMESTIC FUND, LP GROUP MEMBERS: ARIES MASTER FUND II GROUP MEMBERS: ARIES ORION BIOMEDICAL GP, LLC GROUP MEMBERS: LINDSAY A. ROSENWALD, M.D. GROUP MEMBERS: ORION BIOMEDICAL FUND, L.P. GROUP MEMBERS: ORION BIOMEDICAL OFFSHORE FUND, L.P. SUBJECT COMPANY: COMPANY DATA: COMPANY CONFORMED NAME: CYPRESS BIOSCIENCE INC CENTRAL INDEX KEY: 0000716054 STANDARD INDUSTRIAL CLASSIFICATION: BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836] IRS NUMBER: 222389839 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: SC 13G/A SEC ACT: 1934 Act SEC FILE NUMBER: 005-35589 FILM NUMBER: 05600075 BUSINESS ADDRESS: STREET 1: 4350 EXECUTIVE DRIVE,SUITE 325 CITY: SAN DIEGO STATE: CA ZIP: 92121 BUSINESS PHONE: 8584522323 MAIL ADDRESS: STREET 1: 4350 EXECUTIVE DRIVE,SUITE 325 CITY: SAN DIEGO STATE: CA ZIP: 92121 FORMER COMPANY: FORMER CONFORMED NAME: IMRE CORP DATE OF NAME CHANGE: 19920703 FILED BY: COMPANY DATA: COMPANY CONFORMED NAME: ARIES FINANCIAL SERVICES INC CENTRAL INDEX KEY: 0001007000 IRS NUMBER: 000000000 FILING VALUES: FORM TYPE: SC 13G/A BUSINESS ADDRESS: STREET 1: 375 PARK AVENUE STREET 2: SUITE 1501 CITY: NEW YORK STATE: NY ZIP: 10152 BUSINESS PHONE: 2128324379 SC 13G/A 1 v012702.txt UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 Cypress BioScience, Inc ----------------------- (Amendment No.1) Common Stock, no par value per share (Title of Class of Securities) ------------------------------ 232674507 --------- CUSIP Number December 31, 2004 ----------------- (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is filed: [ ] Rule 13d-1(b) [X] Rule 13d-1(c) [ ] Rule 13d-1(d) *The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page. The information required on the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes). Continued on following pages Page 1 of 17 Pages Exhibit Index: Page 16 SCHEDULE 13G CUSIP No. 232674507 Page 2 of 16 - -------------------------------------------------------------------------------- 1 Names of Reporting Persons I.R.S. Identification Nos. of above persons (entities only) PARAMOUNT BIOCAPITAL ASSET MANAGEMENT, INC. - -------------------------------------------------------------------------------- 2 Check the Appropriate Box If a Member of a Group * a. |_| b. |X| - -------------------------------------------------------------------------------- 3 SEC Use Only - -------------------------------------------------------------------------------- 4 Citizenship or Place of Organization DELAWARE - -------------------------------------------------------------------------------- 5 Sole Voting Power Number of 0 Shares ---------------------------------------------------- Beneficially 6 Shared Voting Power Owned By 780,115 Each ---------------------------------------------------- Reporting 7 Sole Dispositive Power Person 0 With ---------------------------------------------------- 8 Shared Dispositive Power 780,115 - -------------------------------------------------------------------------------- 9 Aggregate Amount Beneficially Owned by Each Reporting Person 780,115 - -------------------------------------------------------------------------------- 10 Check Box If the Aggregate Amount in Row (9) Excludes Certain Shares * [ ] - -------------------------------------------------------------------------------- 11 Percent of Class Represented By Amount in Row (9) 2.6% - -------------------------------------------------------------------------------- 12 Type of Reporting Person * CO - -------------------------------------------------------------------------------- * see instructions before filling out SCHEDULE 13G CUSIP No. 232674507 Page 3 of 16 - -------------------------------------------------------------------------------- 1 Names of Reporting Persons I.R.S. Identification Nos. of above persons (entities only) ARIES MASTER FUND II - -------------------------------------------------------------------------------- 2 Check the Appropriate Box If a Member of a Group * a. |_| b. |X| - -------------------------------------------------------------------------------- 3 SEC Use Only - -------------------------------------------------------------------------------- 4 Citizenship or Place of Organization CAYMAN ISLANDS - -------------------------------------------------------------------------------- 5 Sole Voting Power Number of 0 Shares ---------------------------------------------------- Beneficially 6 Shared Voting Power Owned By 327,216 Each ---------------------------------------------------- Reporting 7 Sole Dispositive Power Person 0 With ---------------------------------------------------- 8 Shared Dispositive Power 327,216 - -------------------------------------------------------------------------------- 9 Aggregate Amount Beneficially Owned by Each Reporting Person 327,216 - -------------------------------------------------------------------------------- 10 Check Box If the Aggregate Amount in Row (9) Excludes Certain Shares * [ ] - -------------------------------------------------------------------------------- 11 Percent of Class Represented By Amount in Row (9) 1.1 % - -------------------------------------------------------------------------------- 12 Type of Reporting Person * CO - -------------------------------------------------------------------------------- * see instructions before filling out SCHEDULE 13G CUSIP No. 232674507 Page 4 of 16 - -------------------------------------------------------------------------------- 1 Names of Reporting Persons I.R.S. Identification Nos. of above persons (entities only) LINDSAY A. ROSENWALD, M.D. - -------------------------------------------------------------------------------- 2 Check the Appropriate Box If a Member of a Group * a. |_| b. |X| - -------------------------------------------------------------------------------- 3 SEC Use Only - -------------------------------------------------------------------------------- 4 Citizenship or Place of Organization UNITED STATES - -------------------------------------------------------------------------------- 5 Sole Voting Power Number of 236,039 Shares ---------------------------------------------------- Beneficially 6 Shared Voting Power Owned By 952,401 Each ---------------------------------------------------- Reporting 7 Sole Dispositive Power Person 236,039 With ---------------------------------------------------- 8 Shared Dispositive Power 952,401 - -------------------------------------------------------------------------------- 9 Aggregate Amount Beneficially Owned by Each Reporting Person 1,188,440 - -------------------------------------------------------------------------------- 10 Check Box If the Aggregate Amount in Row (9) Excludes Certain Shares * [ ] - -------------------------------------------------------------------------------- 11 Percent of Class Represented By Amount in Row (9) 3.9% - -------------------------------------------------------------------------------- 12 Type of Reporting Person * IN - -------------------------------------------------------------------------------- * see instructions before filling out SCHEDULE 13G CUSIP No. 232674507 Page 5 of 16 - -------------------------------------------------------------------------------- 1 Names of Reporting Persons I.R.S. Identification Nos. of above persons (entities only) ARIES DOMESTIC FUND, LP - -------------------------------------------------------------------------------- 2 Check the Appropriate Box If a Member of a Group * a. [ ] b. [x] - -------------------------------------------------------------------------------- 3 SEC Use Only - -------------------------------------------------------------------------------- 4 Citizenship or Place of Organization DELAWARE - -------------------------------------------------------------------------------- 5 Sole Voting Power Number of 0 Shares ---------------------------------------------------- Beneficially 6 Shared Voting Power Owned By 378,898 Each ---------------------------------------------------- Reporting 7 Sole Dispositive Power Person 0 With ---------------------------------------------------- 8 Shared Dispositive Power 378,898 - -------------------------------------------------------------------------------- 9 Aggregate Amount Beneficially Owned by Each Reporting Person 378,898 - -------------------------------------------------------------------------------- 10 Check Box If the Aggregate Amount in Row (9) Excludes Certain Shares * [ ] - -------------------------------------------------------------------------------- 11 Percent of Class Represented By Amount in Row (9) 1.3% - -------------------------------------------------------------------------------- 12 Type of Reporting Person * PN - -------------------------------------------------------------------------------- * see instructions before filling out SCHEDULE 13G CUSIP No. 232674507 Page 6 of 16 - -------------------------------------------------------------------------------- 1 Names of Reporting Persons I.R.S. Identification Nos. of above persons (entities only) ARIES DOMESTIC FUND II, LP - -------------------------------------------------------------------------------- 2 Check the Appropriate Box If a Member of a Group * b. [ ] c. [X] - -------------------------------------------------------------------------------- 3 SEC Use Only - -------------------------------------------------------------------------------- 4 Citizenship or Place of Organization DELAWARE - -------------------------------------------------------------------------------- 5 Sole Voting Power Number of 0 Shares ---------------------------------------------------- Beneficially 6 Shared Voting Power Owned By 67,101 Each ---------------------------------------------------- Reporting 7 Sole Dispositive Power Person 0 With ---------------------------------------------------- 8 Shared Dispositive Power 67,101 - -------------------------------------------------------------------------------- 9 Aggregate Amount Beneficially Owned by Each Reporting Person 67,101 - -------------------------------------------------------------------------------- 10 Check Box If the Aggregate Amount in Row (9) Excludes Certain Shares * [ ] - -------------------------------------------------------------------------------- 11 Percent of Class Represented By Amount in Row (9) 0.2% - -------------------------------------------------------------------------------- 12 Type of Reporting Person * PN - -------------------------------------------------------------------------------- * see instructions before filling out SCHEDULE 13G CUSIP No. 232674507 Page 7 of 16 - -------------------------------------------------------------------------------- 1 Names of Reporting Persons I.R.S. Identification Nos. of above persons (entities only) ORION BIOMEDICAL GP, LLC - -------------------------------------------------------------------------------- 2 Check the Appropriate Box If a Member of a Group * d. [ ] e. [X] - -------------------------------------------------------------------------------- 3 SEC Use Only - -------------------------------------------------------------------------------- 4 Citizenship or Place of Organization DELAWARE - -------------------------------------------------------------------------------- 5 Sole Voting Power Number of 0 Shares ---------------------------------------------------- Beneficially 6 Shared Voting Power Owned By 172,286 Each ---------------------------------------------------- Reporting 7 Sole Dispositive Power Person 0 With ---------------------------------------------------- 8 Shared Dispositive Power 172,286 - -------------------------------------------------------------------------------- 9 Aggregate Amount Beneficially Owned by Each Reporting Person 172,286 - -------------------------------------------------------------------------------- 10 Check Box If the Aggregate Amount in Row (9) Excludes Certain Shares * [ ] - -------------------------------------------------------------------------------- 11 Percent of Class Represented By Amount in Row (9) 0.6% - -------------------------------------------------------------------------------- 12 Type of Reporting Person * CO - -------------------------------------------------------------------------------- * see instructions before filling out SCHEDULE 13G CUSIP No. 232674507 Page 8 of 16 - -------------------------------------------------------------------------------- 1 Names of Reporting Persons I.R.S. Identification Nos. of above persons (entities only) ORION BIOMEDICAL FUND, L.P. - -------------------------------------------------------------------------------- 2 Check the Appropriate Box If a Member of a Group * f. [ ] g. [X] - -------------------------------------------------------------------------------- 3 SEC Use Only - -------------------------------------------------------------------------------- 4 Citizenship or Place of Organization DELAWARE - -------------------------------------------------------------------------------- 5 Sole Voting Power Number of 0 Shares ---------------------------------------------------- Beneficially 6 Shared Voting Power Owned By 141,533 Each ---------------------------------------------------- Reporting 7 Sole Dispositive Power Person 0 With ---------------------------------------------------- 8 Shared Dispositive Power 141,533 - -------------------------------------------------------------------------------- 9 Aggregate Amount Beneficially Owned by Each Reporting Person 141,533 - -------------------------------------------------------------------------------- 10 Check Box If the Aggregate Amount in Row (9) Excludes Certain Shares * [ ] - -------------------------------------------------------------------------------- 11 Percent of Class Represented By Amount in Row (9) 0.5% - -------------------------------------------------------------------------------- 12 Type of Reporting Person * PN - -------------------------------------------------------------------------------- * see instructions before filling out SCHEDULE 13G CUSIP No. 232674507 Page 9 of 16 - -------------------------------------------------------------------------------- 1 Names of Reporting Persons I.R.S. Identification Nos. of above persons (entities only) ABINGTON BIOMEDICAL MASTER FUND, LTD. - -------------------------------------------------------------------------------- 2 Check the Appropriate Box If a Member of a Group * h. [ ] i. [X] - -------------------------------------------------------------------------------- 3 SEC Use Only - -------------------------------------------------------------------------------- 4 Citizenship or Place of Organization DELAWARE - -------------------------------------------------------------------------------- 5 Sole Voting Power Number of 0 Shares ---------------------------------------------------- Beneficially 6 Shared Voting Power Owned By 4,900 Each ---------------------------------------------------- Reporting 7 Sole Dispositive Power Person 0 With ---------------------------------------------------- 8 Shared Dispositive Power 4,900 - -------------------------------------------------------------------------------- 9 Aggregate Amount Beneficially Owned by Each Reporting Person 4,900 - -------------------------------------------------------------------------------- 10 Check Box If the Aggregate Amount in Row (9) Excludes Certain Shares * [ ] - -------------------------------------------------------------------------------- 11 Percent of Class Represented By Amount in Row (9) 0.02% - -------------------------------------------------------------------------------- 12 Type of Reporting Person * CO - -------------------------------------------------------------------------------- * see instructions before filling out SCHEDULE 13G CUSIP No. 232674507 Page 10 of 16 - -------------------------------------------------------------------------------- 1 Names of Reporting Persons I.R.S. Identification Nos. of above persons (entities only) ORION BIOMEDICAL OFFSHORE FUND, L.P. - -------------------------------------------------------------------------------- 2 Check the Appropriate Box If a Member of a Group * j. [ ] k. [X] - -------------------------------------------------------------------------------- 3 SEC Use Only - -------------------------------------------------------------------------------- 4 Citizenship or Place of Organization DELAWARE - -------------------------------------------------------------------------------- 5 Sole Voting Power Number of 0 Shares ---------------------------------------------------- Beneficially 6 Shared Voting Power Owned By 30,733 Each ---------------------------------------------------- Reporting 7 Sole Dispositive Power Person 0 With ---------------------------------------------------- 8 Shared Dispositive Power 30,733 - -------------------------------------------------------------------------------- 9 Aggregate Amount Beneficially Owned by Each Reporting Person 30,733 - -------------------------------------------------------------------------------- 10 Check Box If the Aggregate Amount in Row (9) Excludes Certain Shares * [ ] - -------------------------------------------------------------------------------- 11 Percent of Class Represented By Amount in Row (9) 0.02% - -------------------------------------------------------------------------------- 12 Type of Reporting Person * PN - -------------------------------------------------------------------------------- * see instructions before filling out Page 11 of 16 Item 1(a) Name of Issuer: Cypress BioScience, Inc. (the "Issuer"). Item 1(b) Address of the Issuer's Principal Executive Offices: 4350 Executive Drive Suite 325 San Diego, CA 92121 Item 2(a) Name of Person Filing: This statement is filed on behalf of Paramount BioCapital Asset Management, Inc. ("Paramount BioCapital"), Aries Master Fund II ("Aries Master"), Aries Domestic Fund, LP ("Aries I"), Aries Domestic Fund II, LP ("Aries II"), Orion Biomedial GP, LLC ("Orion GP"), Orion Biomedical Fund, LP ("Orion"), Orion Biomedical Offshore Fund, LP ("Orion Offshore"), Abington Biomedical Master Fund, Ltd. ("Abington") and Lindsay A. Rosenwald, M.D. ("Dr. Rosenwald" and collectively, the "Reporting Persons"). Shares previously held by Aries Master, Ltd., Aries Master I LLC and Aries Master II LLC have been transferred to Aries Master, Aries I and Aries II respectively. Dr. Rosenwald is an investment banker, venture capitalist, fund manager and sole stockholder and chairman of Paramount BioCapital. Paramount BioCapital is the managing member to each of Aries I and Aries II and the investment manager to Aries Master. Dr. Rosenwald is also the managing member of Orion GP, which is the general partner to each of Orion and Orion Offshore. Item 2(b) Address of Principal Business Office or, if None, Residence: The address of the principal business office of Paramount BioCapital, Aries I, Aries II, Orion, Orion Offshore and Dr. Rosenwald is 787 Seventh Avenue, 48th Floor, New York, New York, 10019. The address of the principal business office of Aries Master and Abington is c/o Fortis Fund Services Cayman Limited, Grand Pavilion Commercial Center, 802 West Bay Road, Grand Cayman, Cayman Islands. Item 2(c) Citizenship: 1) Paramount BioCapital is a Subchapter S corporation incorporated in Delaware; 2) Aries Master and Abington are Cayman Islands exempted companies; 3) Aries I, Aries II, and Orion GP are Delaware limited liability companies; 4) Orion is a Delaware limited partnership; 5) Orion Offshore is a Cayman Islands limited partnership; and 6) Dr. Rosenwald is a citizen of the United States. Item 2(d) Title of Class of Securities: Common Stock (the "Shares"). Page 12 of 16 Item 2(e) CUSIP Number: 232674507 Item 3. If this statement is filed pursuant to Rule 13d-1(b), or 13d-2(b) or (c), check whether the person filing is a: This Item 3 is not applicable. Item 4. Ownership: Item 4(a) Amount Beneficially Owned: Each of the Reporting Persons may be deemed the beneficial owner of the following number of Shares: (i) Paramount BioCapital may be deemed to own 780,115 Shares, which includes the Shares owned by Aries Master, Aries I, Aries II, and Abington. (ii) Aries Master may be deemed the beneficial owner of 327,216 Shares (iii) Aries I may be deemed the beneficial owner of 378,898 Shares (iv) Aries II may be deemed the beneficial owner of 67,101 Shares (v) Orion GP may be deemed the beneficial owner of 172,286 Shares, which includes the Shares owned by Orion and Orion Offshore. (vi) Orion may be deemed the beneficial owner of 141,533 Shares (vii) Orion Offshore may be deemed the beneficial owner of 30,733 Shares (viii) Abington may be deemed the beneficial owner of 4,900 Shares (ix) Dr. Rosenwald may be deemed the beneficial owner of 1,186,440 Shares as follows: (a) all shares described in (i) - (vii) above; and (c) 128,471 Shares and warrants to purchase 107,568 Shares owned directly by Dr. Rosenwald. Item 4(b) Percent of Class: Please see Item 11 of each cover page. Page 13 of 16 Item 4(c) Number of shares as to which such person has:
(i) Sole power to vote or direct the vote: Please see Item 5 of each cover page (ii) Shared power to vote or to direct the vote Please see Item 6 of each cover page (iii) Sole power to dispose or to direct the disposition of Please see Item 7 of each cover page (iv) Shared power to dispose or to direct the disposition of Please see Item 8 of each cover page
Item 5. Ownership of Five Percent or Less of a Class: If this statement is being filed to report the fact that the Reporting Person has ceased to be the beneficial owner of more than five percent of a class of securities of the Issuer, check the following box. |X| During 2004, the Reporting Persons, individually and collectively, ceased to be a beneficial owner of more than 5% of any class of securities of the Issuer. Item 6. Ownership of More than Five Percent on Behalf of Another Person: This Item 6 is not applicable. Item 7. Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company: This Item 7 is not applicable. Item 8. Identification and Classification of Members of the Group: This Item 8 is not applicable. Item 9. Notice of Dissolution of Group: This Item 9 is not applicable. Item 10. Certification: By signing below each of the Reporting Persons certifies that, to the best of such person's knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the Issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having such purpose or effect. Page 14 of 16 SIGNATURES After reasonable inquiry and to the best of my knowledge and belief, the undersigned certifies that the information set forth in this statement is true, complete and correct, as of this February 10, 2005. LINDSAY A. ROSENWALD, M.D. PARAMOUNT BIOCAPITAL ASSET MANAGEMENT, INC. By /s/LINDSAY A. ROSENWALD By: /s/ LINDSAY A. ROSENWALD ------------------------------ --------------------------- Name: Lindsay A. Rosenwald, M.D. Title: Chairman ORION BIOMEDICAL GP, LLC ARIES MASTER FUND II By: Paramount BioCapital Asset Management, Inc. By: /s/LINDSAY A. ROSENWALD Its: Investment Manager Name: Lindsay A. Rosenwald, M.D. Title: Managing Member By: /s/ LINDSAY A. ROSENWALD --------------------------- Name: Lindsay A. Rosenwald, M.D. ORION BIOMEDICAL FUND, LP Title: Chairman By: Orion Biomedical GP, LLC. ARIES DOMESTIC FUND, L.P. Its General Partner By: Paramount BioCapital Asset Management, Inc. By: /s/ LINDSAY A. ROSENWALD Name: Lindsay A. Rosenwald, M.D. Its Managing Manager Title: Managing Member By: /s/ LINDSAY A. ROSENWALD --------------------------- Name: Lindsay A. Rosenwald, M.D. ORION BIOMEDICAL Title: Chairman OFFSHORE FUND, LP By: Orion Biomedical GP, LLC. ARIES DOMESTIC FUND II, L.P. Its General Partner By: /s/ LINDSAY A. ROSENWALD By: Paramount BioCapital Asset --------------------------- Management, Inc. Name: Lindsay A. Rosenwald, M.D. Its Managing Manager Title: Managing Member By: /s/ LINDSAY A. ROSENWALD ABINGTON BIOMEDICAL MASTER FUND, LTD Name: Lindsay A. Rosenwald, M.D. Title: Chairman By: Paramount BioCapital Asset Management, Inc. Its: Investment Manager By: /s/ LINDSAY A. ROSENWALD Name: Lindsay A. Rosenwald, M.D. Title: Chairman Page 15 of 16 EXHIBIT INDEX
Page No. A. Joint Filing Agreement, dated as of February 10, 2005, by and among Paramount BioCapital Asset Management, Inc., Aries Master Fund II, Aries Domestic Fund, LP, Aries Domestic Fund II, LP, Abington Biomedical Master Fund, Ltd., Orion BioMedical Fund, LP, Orion BioMedical 16 Offshore Fund, LP, Orion BioMedical GP, LLC and Lindsay A. Rosenwald, M.D...................
Page 16 of 16 EXHIBIT A JOINT FILING AGREEMENT The undersigned hereby agree that the statement on Schedule 13G with respect to the Common Stock of Cypress BioSciences, Inc. dated as of February 10, 2005, is, and any amendments thereto signed by each of the undersigned shall be, filed on behalf of each of us pursuant to and in accordance with the provisions of Rule 13d-1(k) under the Securities Exchange Act of 1934. LINDSAY A. ROSENWALD, M.D. PARAMOUNT BIOCAPITAL ASSET MANAGEMENT, INC. By /s/LINDSAY A. ROSENWALD By: /s/ LINDSAY A. ROSENWALD ------------------------------ --------------------------- Name: Lindsay A. Rosenwald, M.D. Title: Chairman ORION BIOMEDICAL GP, LLC ARIES MASTER FUND II By: Paramount BioCapital Asset Management, Inc. By: /s/LINDSAY A. ROSENWALD Its: Investment Manager Name: Lindsay A. Rosenwald, M.D. Title: Managing Member By: /s/ LINDSAY A. ROSENWALD --------------------------- Name: Lindsay A. Rosenwald, M.D. ORION BIOMEDICAL FUND, LP Title: Chairman By: Orion Biomedical GP, LLC. ARIES DOMESTIC FUND, L.P. Its General Partner By: Paramount BioCapital Asset Management, Inc. By: /s/ LINDSAY A. ROSENWALD Name: Lindsay A. Rosenwald, M.D. Its Managing Manager Title: Managing Member By: /s/ LINDSAY A. ROSENWALD --------------------------- Name: Lindsay A. Rosenwald, M.D. ORION BIOMEDICAL Title: Chairman OFFSHORE FUND, LP By: Orion Biomedical GP, LLC. ARIES DOMESTIC FUND II, L.P. Its General Partner By: /s/ LINDSAY A. ROSENWALD By: Paramount BioCapital Asset --------------------------- Management, Inc. Name: Lindsay A. Rosenwald, M.D. Its Managing Manager Title: Managing Member By: /s/ LINDSAY A. ROSENWALD ABINGTON BIOMEDICAL MASTER FUND, LTD Name: Lindsay A. Rosenwald, M.D. Title: Chairman By: Paramount BioCapital Asset Management, Inc. Its: Investment Manager By: /s/ LINDSAY A. ROSENWALD Name: Lindsay A. Rosenwald, M.D. Title: Chairman -----END PRIVACY-ENHANCED MESSAGE-----