The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABBVIE INC COM 00287Y109   14,074,530 90,821 SH   SOLE NONE 90,821 0 0
APOGEE THERAPEUTICS INC COM 03770N101   290,045 10,381 SH   SOLE NONE 10,381 0 0
ARGENX SE SPONSORED ADR 04016X101   13,025,162 34,238 SH   SOLE NONE 34,238 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108   12,847,147 190,752 SH   SOLE NONE 190,752 0 0
AXSOME THERAPEUTICS INC COM 05464T104   6,991,822 87,848 SH   SOLE NONE 87,848 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101   2,785,092 28,885 SH   SOLE NONE 28,885 0 0
BIOMEA FUSION INC COM 09077A106   369,563 25,452 SH   SOLE NONE 25,452 0 0
CHARLES RIV LABS INTL INC COM 159864107   1,632,342 6,905 SH   SOLE NONE 6,905 0 0
CYTOKINETICS INC COM NEW 23282W605   2,681,114 32,113 SH   SOLE NONE 32,113 0 0
CYTOKINETICS INC CALL 23282W905   33,805,101 404,900 SH Call SOLE NONE 404,900 0 0
CYTOKINETICS INC PUT 23282W955   33,437,745 400,500 SH Put SOLE NONE 400,500 0 0
ELI LILLY & CO COM 532457108   53,974,312 92,593 SH   SOLE NONE 92,593 0 0
ELI LILLY & CO PUT 532457958   23,316,800 40,000 SH Put SOLE NONE 40,000 0 0
EYEPOINT PHARMACEUTICALS INC COM NEW 30233G209   1,155,500 50,000 SH   SOLE NONE 50,000 0 0
GRITSTONE BIO INC COM 39868T105   194,147 95,170 SH   SOLE NONE 95,170 0 0
IMMUNOVANT INC COM 45258J102   901,456 21,397 SH   SOLE NONE 21,397 0 0
INSMED INC COM PAR $.01 457669307   2,322,267 74,936 SH   SOLE NONE 74,936 0 0
INTRA-CELLULAR THERAPIES INC COM 46116X101   2,979,392 41,600 SH   SOLE NONE 41,600 0 0
MERCK & CO INC COM 58933Y105   35,889,384 329,200 SH   SOLE NONE 329,200 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109   5,929,200 45,000 SH   SOLE NONE 45,000 0 0
NOVO-NORDISK A S ADR 670100205   74,639,899 721,507 SH   SOLE NONE 721,507 0 0
OCULAR THERAPEUTIX INC COM 67576A100   1,962,400 440,000 SH   SOLE NONE 440,000 0 0
PLIANT THERAPEUTICS INC COM 729139105   1,811,000 100,000 SH   SOLE NONE 100,000 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102   2,575,956 112,340 SH   SOLE NONE 112,340 0 0
RAPT THERAPEUTICS INC COM 75382E109   488,004 19,638 SH   SOLE NONE 19,638 0 0
STRUCTURE THERAPEUTICS INC PUT 86366E956   407,600 10,000 SH Put SOLE NONE 10,000 0 0
TYRA BIOSCIENCES INC COM 90240B106   142,004 10,253 SH   SOLE NONE 10,253 0 0
VAXCYTE INC COM 92243G108   2,421,254 38,555 SH   SOLE NONE 38,555 0 0
VERONA PHARMA PLC SPONSORED ADS 925050106   2,600,105 130,790 SH   SOLE NONE 130,790 0 0
VIKING THERAPEUTICS INC COM 92686J106   7,138,424 383,580 SH   SOLE NONE 383,580 0 0
WATERS CORP COM 941848103   936,659 2,845 SH   SOLE NONE 2,845 0 0