Exhibit 107

Calculation of Filing Fee Tables

Post-Effective Amendment No 1 to Form S-3

(Form Type)

Generation Bio Co.

(Exact Name of Registrant as Specified in its Charter)

Table 1—Newly Registered and Carry Forward Securities

	Security Type	Security Class Title	Fee   Calculation   or Carry   Forward   Rule	Amount   Registered	Proposed   Maximum   Offering   Price Per   Unit	Maximum   Aggregate   Offering Price	Fee Rate	Amount of   Registration   Fee	Carry   Forward   Form   Type	Carry   Forward   File   Number	Carry   Forward   Initial   effective   date	Filing Fee   Previously   Paid In   Connection   with   Unsold   Securities   to be   Carried   Forward
Newly Registered Securities
Fees to Be Paid	Debt	Debt Securities	(1)	(1)	(1)	(1)	(1)	(1)	—	—	—	—
Fees to Be Paid	Equity	Common Stock, par value $0.0001 per share	(1)	(1)	(1)	(1)	(1)	(1)	—	—	—	—
Fees to Be Paid	Equity	Preferred Stock, par value $0.0001 per share	(1)	(1)	(1)	(1)	(1)	(1)	—	—	—	—
Fees to Be Paid	Other	Units(3)	(1)	(1)	(1)	(1)	(1)	(1)	—	—	—	—
Fees to Be Paid	Other	Warrants	(1)	(1)	(1)	(1)	(1)	(1)	—	—	—	—
Fees to be Paid	Unallocated (Universal) Shelf	Unallocated (Universal) Shelf	457(o)	(1)	(1)	$600,000,000(1)	$92.70 per $1,000,000	$55,620	—	—	—	—
Fees Previously Paid	Equity	Common Stock, par value $0.0001 per share	457(o)	(2)	(2)	$250,000,000(2)	$109.10 per $1,000,000	$27,275	—	—	—	—
Carry Forward Securities
Carry Forward Securities	—	—	—	—	—	—	—	—	—	—	—	—
	Total Offering Amounts					$600,000,000(1)	—	$55,620
	Total Fees Previously Paid							$27,275(2)
	Total Fee Offsets							$0.00
	Net Fee Due							$32,445(2)

(1) Pursuant to Instruction 2.A(iii)(b) of Item 16(b) of Form S-3, this information is not required to be included. An indeterminate amount of the securities of each identified class is being registered as may from time to time be offered under this registration statement at indeterminate prices, along with an indeterminate number of securities that may be issued upon exercise, settlement, exchange or conversion of securities offered or sold under this registrations statement, as shall have an aggregate initial offering price up to $600,000,000, including shares of common stock with an aggregate offering price of up to $250,000,000 previously registered under this registration statement on August 11, 2021. Pursuant to Rule 416 under the Securities Act of 1933, as amended, or the Securities Act, this registration statement also covers any additional securities that may be offered or issued in connection with any stock split, stock dividend or pursuant to anti-dilution provisions of any of the securities. Separate consideration may or may not be received for securities that are issuable upon conversion, exercise or exchange of other securities.

(2) The Net Fee relates to the additional $350,000,000 of securities to be sold by the registrant registered hereunder. As a result, a registration fee of $32,445 is being paid herewith.

(3) Units may be issued under a unit agreement and will represent an interest in one or more securities registered under this registration statement including shares of common stock or preferred stock, debt securities or warrants, in any combination, which may or may not be separable from one another.