Exhibit 10.18

SUBLEASE AGREEMENT

THIS SUBLEASE (the “Sublease”) is made effective this 9th day of June, 2017 by and between Paidion Research, Inc. a North Carolina corporation (“Sublessor”) and  Dova Pharmaceuticals, Inc., a Delaware corporation (“Sublessee”);

WHEREAS, Pursuant to that certain Office Lease Agreement dated April 10, 2014 by and between Sublessor, as tenant, and Palladian Center, LLC, a Delaware limited liability company (“Landlord”), (as amended by First Amendment to Lease dated September 18, 2015, the “Master Lease”), Sublessor leases from Landlord all of Suites 245 and 250 on the second floor of the Palladian II building at 240 Leigh Farm Road, Durham, North Carolina  (a copy of the Master Lease being attached hereto as Exhibit A); and

WHEREAS, Sublessor and Sublessee have agreed that Sublessor will sublease to Sublessee and Sublessee will sublease from Sublessor all of Suite 245 (together with a small portion of Suite 250) consisting of approximately 7,351 rentable square feet of space, as more particularly shown on Exhibit B, attached hereto and made a part hereof (the “Subleased Premises”), pursuant to the terms of this Sublease:

NOW THEREFORE, for good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the parties hereto agree as follows:

1.             Recitals; Definitions.  The recitals set out above are true and accurate and are incorporated herein by this reference.  All capitalized terms used, but not defined, in this Sublease shall have the meanings given to such terms in the Master Lease.

2.             Sublease of Premises.  Sublessor hereby subleases to Sublessee, and Sublessee hereby accepts and subleases from Sublessor, the Subleased Premises, together with (i) the nonexclusive right to use the Common Areas; and (ii) the non-exclusive right to use 4 unreserved parking spaces per 1,000 rentable square feet of the Subleased Premises (or portion thereof) in the surface parking areas adjacent to the Building which constitute a portion of the Common Areas.

3.             Term of Sublease; Minimum Rental.  The term of this Sublease will commence on June 1, 2017 and shall end with the expiration of the Master Lease on April 30, 2020 (the “Sublease Term”).   The monthly rental under this Sublease (the “Minimum Rental”) is as follows:

June 1, 2017 to May 31, 2018	$177,232.61 per year	$14,769.38 per month
June 1, 2018 to May 31, 2019	$182,549.58 per year	$15,212.46 per month
June 1, 2019 to April 30, 2020	$172,357.21 for eleven months until expiration	$15,668.84 per month

4.             Sublessee’s Business. Sublessee shall use the Subleased Premises for general office use and for no other purpose.

5.             Payment of Minimum Rental. The monthly Minimum Rental for the Subleased Premises throughout the Term of this Agreement is set forth in paragraph 3, above.  Sublessee will arrange for monthly Minimum Rental to be paid to Sublessor on or prior to the first day of every month during the Term of this Sublease by wire or ACH transfer rather than by check.  Sublessor will provide appropriate account information to Sublessee.  Sublessee will not be required to participate in Tenant’s Contribution for Operating Expenses under Article 4 of the Master Lease.

6.             Sublessee’s Care/Hold Harmless. Sublessee will commit no act of waste, will maintain the Subleased Premises in a neat and orderly condition (including being responsible for maintaining all kitchen equipment during the Sublease term) and will comply with all laws, regulations, rules and orders of any federal, state or local government agencies or departments; provided, however, that Sublessee shall not be required to comply with or cause the Subleased Premises to comply with any laws, rules, regulations or requirements requiring the construction of alterations unless such compliance is necessitated solely due to Sublessee’s particular use of the Subleased Premises or any alterations constructed by Sublessee in the Subleased Premises. Sublessee will not damage the Subleased Premises and will do nothing that could increase the cost of Sublessor’s fire or public liability insurance. Sublessee agrees to hold Sublessor and Landlord harmless against any damages, claims, demands or causes of action caused by Sublessee, or its agents or employees, at or around the Subleased Premises, except to the extent caused by the negligence, breach of contract, willful misconduct or unlawful act of Sublessor, Landlord or their respective agents or employees.

7.             Underlying Master Lease. Except for Section 4 of the Master Lease and as otherwise set forth herein, Sublessee shall comply with the terms under the Master Lease that relate and are allocable to the Subleased Premises, provided, however, that to the extent of a conflict between the terms of the Master Lease and the terms of this Sublease, this Sublease shall control.  Except for those provisions that are inconsistent with the terms of this Sublease or otherwise not applicable pursuant to the terms of this Sublease, the terms of the Master Lease, to the extent relating and allocable to the Subleased Premises, are incorporated herein by this reference as if Sublessor were the “Landlord” and Sublessee were the “Tenant” thereunder;  provided, however, Sublessor does not make any of the representations of the Landlord under the Master Lease and does not undertake to perform and observe any of the terms, covenants and conditions on the part of the Landlord to be performed or observed by the Landlord, but Sublessor shall use its commercially reasonable efforts to cause the Landlord to perform or observe such terms, covenants and conditions as they may apply to the Subleased Premises.  Sublessor shall have no obligation to make repairs or replacements to the Subleased Premises,

Sublessee agreeing that during the Term of this Sublease it shall be responsible for all of Sublessor’s repair and maintenance obligations with respect to the Subleased Premises under the Master Lease as if it were the “Tenant” thereunder.

8.             Warranty by Sublessor. Sublessor warrants and represents to Sublessee that the Master Lease has not been amended or modified except as provided herein and that neither Sublessor nor, to Sublessor’s knowledge, Landlord is in default of any of the provisions of the Master Lease.

9.             Improvements; Demising Wall/Entrance; Signage. Sublessee acknowledges it is accepting the Subleased Premises “as is” and may make no alterations thereto; provided, however, that Sublessee may install its telephone and Internet connections and services (but shall not cause any interruptions in such services to Sublessor thereby).  In addition, Sublessor shall construct the  demising wall shown on Exhibit C separating the Subleased Premises from the Suite 250 Space that Sublessor will continue to use and lease from Landlord under the Master Lease (the “Demising Wall”).  Sublessor will obtain all approvals necessary with respect to the Demising Wall.  Sublessor shall install the Demising Wall in accordance with all applicable laws and in a good and workmanlike manner.  Upon completion of the Demising Wall, Sublessee shall pay to Sublessor the lesser of (i) 50% of the Sublessor’s actual out-of-pocket costs associated with the construction of the Demising Wall and (ii) $15,000, as full reimbursement for Sublessee’s share of the cost thereof.  Sublessee acknowledges that construction of the Demising Wall may extend somewhat beyond the commencement date of the Sublease Term and consents to the same.  Sublessor and Sublessee will work together practically and in good faith so that such construction can be completed as quickly as possible.

In addition, Sublessor shall install standard building signage for Sublessee for the Subleased Premises in the Building lobby and shall also assist in providing key-card access for Sublessee, both at Sublessee’s expense.  If permitted by Landlord, Sublessee may install, at Sublessee’s sole cost and expense, identification signage on a monument sign for the Building in a location determined by Landlord in accordance with building standards and subject to any applicable governmental laws or regulations (the “Monument Sign”).  Sublessee shall maintain the Monument sign at Sublessee’s sole cost and expense.  At the end of the Sublease Term or earlier removal of the Monument Sign, Sublessee shall pay all costs to remove the Monument Sign and repair any damage caused thereby.  Sublessor shall use commercially reasonable efforts to seek Landlord’s approval of the Monument Sign.  Additionally, after the Demising Wall has been completed, Sublessee shall have the right, at its expense, to create and install signage in the Subleased Premises or on the glass door at the entrance of the Subleased Premises in accordance with plans approved in advance in writing by Landlord.

10.          Surrender; Abandoned Property. Sublessee will return the Subleased Premises to Sublessor at the end of the Term of this Sublease in substantially the same condition as received from Sublessor at the beginning of the Term, ordinary wear and tear, casualty, condemnation and repairs that are not Sublessee’s obligations hereunder excepted. All of Sublessee’s personal property remaining in the Subleased Premises for longer than fifteen (15) days after this Sublease terminates shall be deemed abandoned and may be removed or stored by Sublessor at Sublessee’s risk and expense.

11.          Assignment or Subletting. Sublessee shall not assign or encumber this Sublease or sublet the Subleased Premises without Sublessor’s and Landlord’s prior written consent to the extent and as provided in the Master Lease.  Sublessor shall not unreasonably withhold its consent.

12.          Sublessor’s and Sublessee’s Remedies. If Sublessee defaults in the payment of Minimum Rental or in the payment of any other amounts due to Sublessor hereunder or Sublessee defaults in the performance of any of the covenants or conditions of this Sublease, Sublessor may give Sublessee notice of the default. If Sublessee does not cure any default within ten (10) days for monetary default and thirty (30) days for non-monetary default after the giving of notice (or, in the case of any non-monetary default that cannot be cured within thirty (30) days, proceed with reasonable diligence and in good faith to cure such non-monetary default within such 30-day period), Sublessor may terminate this Sublease or, without such termination, terminate Sublessee’s right to possession and relet the Subleased Premises, in each case by written notice to Sublessee (a “Termination Notice”), holding Sublessee responsible for, and Sublessee shall pay, all costs and expenses of such reletting in addition to Minimum Rental as the same shall continue to accrue.  On the date specified in the Termination Notice, this Sublease or Sublessee’s right to possession, as applicable, shall terminate as a result of Sublessee’s uncured default, and Sublessee shall at once quit and surrender the Subleased Premises to Sublessor, and Sublessor may thereafter re-enter and re-take possession of the Subleased Premises as permitted by applicable law and remove Sublessee or other occupants and their property. In addition to such remedies, in the event of a default by Sublessee, Sublessor shall have all rights and remedies available at law or in equity, all remedies being cumulative. In the event of a default by Sublessor hereunder that is not cured within the same time frame provided for a Sublessee default, above, (or, with respect to the Master Lease, within the cure period provided therein) Sublessee shall have all rights and remedies as may be available at law and in equity.

13.          Waiver of Performance; Entire Agreement; Amendments. The performance of or compliance with a party’s obligation hereunder may be waived, but only in writing signed by an authorized representative of the applicable counterparty or counterparties.  A waiver of compliance with any provision of this Sublease shall not constitute a waiver of any subsequent lack of compliance with such provision or of any other provision of this Sublease.  Except as provided in this Sublease, no delay or failure on the part of either party in exercising any right, power or privilege hereunder shall operate as a waiver thereof, nor shall any waiver on the part of either party of any such right, power or privilege, nor any single or partial exercise thereof, preclude any other or further exercise thereof or the exercise of any other right, power or privilege hereunder.

This Sublease together with the Exhibits hereto and Bill of Sale executed in connection herewith, is intended by the parties as a final expression of their agreement and as a complete and exclusive statement of the terms of their agreement with respect to its subject matter.  This Sublease may not be contradicted by evidence of any prior or contemporaneous agreement, oral or written, and this Sublease may not be explained or supplemented by evidence of consistent additional terms.  No previous course of dealing will be admissible to explain, modify or contradict the terms of this Sublease.  This Sublease supersedes, merges, and voids all prior

representations, statements, negotiations, understandings, proposed agreements, and other agreements, written or oral, relating to its subject matter.

This Sublease may not be amended, modified or supplemented except by a writing executed by all parties.

14.          Subordination. This Sublease is subject and subordinate to Master Lease, and to any mortgages that may at any time affect the real property of which the Subleased Premises forms a part, and also to all renewals, modifications, consolidations and replacements of the underlying mortgages. Although no instrument or act on the part of Sublessee is needed to effectuate such subordination, Sublessee will, nevertheless, execute and deliver any instruments confirming the subordination of this Sublease that the holders of the mortgages or that Sublessor or Landlord may reasonably request.

15.          Sublessor May Cure Defaults. If Sublessee defaults in the performance of any covenant or condition of this Sublease, Sublessor may, on reasonable notice to Sublessee (except that no notice need be given in case of emergency), cure the default at Sublessee’s expense and the reasonable amount of all expenses, including reasonable attorneys’ fees, incurred by Sublessor shall be deemed an additional amount owed by Sublessee to Sublessor payable within fifteen (15) days of demand therefor.

16.          Notices. Any notice by either party to the other shall be in writing and shall be deemed to be properly given only if delivered personally or by recognized overnight delivery service or mailed by registered or certified mail, return receipt requested, addressed (a) if to Sublessor: Paidion Research, Inc., 240 Leigh Farm Road, Suite 250, Durham, NC 27707, (b) if to Sublessee: Dova Pharmaceuticals, Inc., 240 Leigh Farm Road, Suite 245, Durham, NC 27707, or (c) at such addresses as Sublessee or Sublessor from time to time may designate in writing. Notice shall be deemed to have been given upon delivery if delivered personally, and if mailed, upon the third day after the date of mailing, or if sent by overnight delivery, the day after the date deposited with the overnight delivery service.

17.          Sublessor’s Right to Inspect Subleased Premises. Subject to providing no less than twenty-four (24) hours’ prior written notice and agreeing at all times to be accompanied by an employee or representative of Sublessee, Sublessor may enter the Subleased Premises at any reasonable time (except that no notice is needed in case of emergency) to inspect the Subleased Premises and/or, if necessary, to make repairs to the Subleased Premises.

18.          Interruption of Services or of Occupancy. Interruption or curtailment of any service maintained in the building containing the Subleased Premises if caused by strikes, mechanical difficulties, or any other causes beyond Landlord’s or Sublessor’s control shall not entitle Sublessee to any claim against Sublessor or to any abatement in amounts due, nor shall they constitute constructive or partial eviction, and Sublessor shall have no responsibility to restore the Subleased Premises.

19.          Sublessee to Execute Estoppel Certificate. Sublessee shall upon not less than ten (10) days’ prior written request by Sublessor or Landlord execute, acknowledge and deliver to the requesting party a written statement certifying that this Sublease is unmodified and in full

force and effect (or that the Sublease is in full force and effect as modified, listing the instruments of modification), the dates to which the rent and other charges have been paid, and whether or not to the best of Sublessee’s knowledge the requesting party is in default (and if so, specifying the nature of the default), it being intended that any statement delivered pursuant to this paragraph of the Sublease may be relied upon by a prospective purchaser or mortgagee of the requesting party’s interest in the building or prospective assignee of any mortgage upon the requesting party’s interest in the building.

20.          Agreement Binding on Successors, Representatives and Assigns. The provisions of this Sublease shall apply to, bind and inure to the benefit of Sublessor and Sublessee, their successors, legal representatives and assigns.

21.          Inapplicable Exhibits. The parties agree that the following Exhibits to the Master Lease shall not apply to this Sublease: Exhibit A, Exhibit A-1, Exhibit C (Work Letter) and Exhibit D.

22.          Insurance. Prior to the commencement of the Term of this Sublease, Sublessee shall provide certificates of insurance as required by “Tenant” as set forth in Article 9 of the Master Lease, which certificates shall name both Landlord and Sublessor as additional insured parties consistent with the provisions of the Master Lease.  Notwithstanding anything to the contrary herein, Sublessor and Sublessee hereby release each other, and their respective agents, employees, subtenants, and contractors, from all liability for damage to any property that is caused by or results from a risk which is actually insured against or which would normally be covered by “all risk” property insurance, without regard to the negligence or willful misconduct of the entity so released.

23.          Security Deposit. Sublessee shall pay to Sublessor within seven (7) business days of execution of this Sublease a security deposit of $14,481.47, which Sublessor will return to Sublessee within a reasonable time (not to exceed thirty (30) days) after the expiration or earlier termination of this Sublease after deducting any amounts therefrom that are permitted to be used by Sublessor under this Section.  In the event of any damage to the Premises or in the event of non-payment by Sublessee of its monetary obligations under this Sublease, Sublessor may deduct the cost amount thereof from the security deposit. The rights and obligations contained in this Section 22 shall survive termination of this Sublease.

24.          Landlord Consent; Condition to Sublease.  It shall be a condition precedent to the effectiveness of this Sublease that Landlord shall have consented to this Sublease (including consenting to the construction of the Demising Wall), which consent may be given by Landlord’s signature below or in a separate consent form from Landlord, at Landlord’s election.

[SIGNATURE PAGE FOLLOWS]

IN WITNESS WHEREOF, the parties have caused this Sublease to be executed by their duly authorized representatives, effective as of the date set out above.

SUBLESSOR:
PAIDION RESEARCH, INC.
By:		/s/ Barry Mangum
Printed Name:				Barry Mangum
Title:			CEO
SUBLESSEE:
DOVA PHARMACEUTICALS, INC.
By:	_/s/ Douglas Blankenship
Printed Name:				Douglas Blankenship
Title:			CFO

EXHIBIT A

[Master Lease]

OFFICE LEASE AGREEMENT BY AND BETWEEN PALLADIAN CENTER LLC, a Delaware limited liability co {AS LANDLORD) AND PAIDION RESEARCH, INC., a North Carolina corporati {AS TENANT)

TABLE OF CONTENTS BASIC LEASE TERMS .................................................................... 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 25. 26. 27. 28. 29. 30. 31. 32. 33. 34. 35. 36. DESCRlPTION OF PREMISES ....................................................... TERM; COMMENCEMENT DATE; DELIVERY OF PREMISES RENTAL ........................................................................................... ALTERATIONS AND IMPROVEMENTS BY TENANT .............. USE OF PREMISES......................................................................... SERVICESBYLANDLORD .......................................................... TAXES ONLEASEANDTENANT'SPROPERTY...................... INSURANCE AND INDEMNITY .................................................. LANDLORD'S COVENANTTOREPAIRANDREPLACE ........ PROPERTY OF TENANT ............................................................... TRADE FIXTURES AND EQUIPMENT ........................................ DAMAGE OR DESTRUCTION OF PREMISES ............................ GOVERNMENTAL ORDERS ......................................................... MUTUAL WAIVER OF SUBROGATION...................................... SIGNS AND ADVERTISING ......................................................... LANDLORD'S RIGHT OF ENTRY ................................................ INTENTIONALLY OMITTED ........................................................ EMINENT DOMAIN ....................................................................... EVENTS OF DEFAULT AND REMEDIES .................................... SUBORDINATION.......................................................................... ASSIGNMENT AND SUBLETTING .............................................. LANDLORD DEFAULT .................................................................. TRANSFER OF LANDLORD'S INTEREST................................... COVENANT OF QUIET ENJOYMENT ......................................... ESTOPPEL CERTIFICATES ........................................................... PROTECTION AGAINST LIENS.................................................... MEMORANDUM OF LEASE.......................................................... FORCE MAJEURE .......................................................................... REMEDIES CUMULATIVE--NONWAIVER............................... HOLDING OVER ............................................................................ NOTICES........................................................................................... LEASING COMMISSION ................................................................ MISCELLANEOUS .......................................................................... SEVERABILITY.............................................................................. RIGHT OF FIRST OFFER................................................................

STATE OF NORTH CAROLINA COUNTY OF DURHAM TIDS LEASE AGREEMENT (the "Lease") made and entered into :----,-----::'' 2014, by and between PALLADIAN CENTER LLC, a Delaware li hereinafter called "Landlord"; and PAIDION RESEARCH, INC., a Nmt hereinafter called "Tenant": In consideration of the mutual covenants and agreements contained h agree for themselves, their successors and assigns, as follows: BASIC LEASE TERMS. 1. The following terms shall have the following meanings in this Lease: (a) Premises: Suite 250 ("Suite 250") containing approximately 7,4 office space on the second floor of the Building, as more pa1t floor plan attached hereto as Exhibit "A". As further described in Section 3(b) below, on Aplil I, 201 expanded by adding to the Premises Suite 245 ("Suite 245") c 6,941 rentable square feet of office space on the second floor particularly described on the floor plan attached hereto as Exhi such date the Premises shall contain 14,378 rentable square feet. (b) Building: Palladian II, located at 240 Leigh Farm Road, Durham (c) Business Park: Palladian Corporate Center. (d) Common Areas: All areas of the Building or the Business Park a use or benefit of all tenants primarily or to the public gene limitation, parking areas, driveways, sidewalks, loading docks elevators, stailwells, entrances, public restrooms, mechanical r telephone rooms, mail rooms, electrical rooms, and other simila providing for building systems, and any other common facilitie from time to time. (e) Commencement Date: May I, 2014 (subject to adjustment purs Lease).

month then the Expiration Date shall be extended to the last day would otherwise fall. (g) Minimum Rental: PERIOD RATE (per rentable square foot) MONTHLY MINIMUM RENTAL 05/01/14-04/30/15 05/01/!5-09/30/15* 10/01/15-04/30/16 05/01/16-03/31/17 04/01/!7 -04/30/!7** 05101/17-06/30/17** 07/01/!7-04/30/18 05/01/18-04/30/19 05/01/19-04/30/20 - o long as Tenant is not in *S default under this Lease, during the five 05/01/2015 until 09/30/2015 Minimum Rental shall abate by 100% for S Minimum Rental table above (the "Suite 250 Abatement Period"). --------- - (h) Operating Expense Stop: Actual Operating Expenses for the cale (i) Tenant's Proportionate Share: A fraction, the numerator of whic rentable square feet within the Premises and the denominator munber of rentable square feet within the Building, currently esti + 100,546) until 04/01/2017 at which time it shall increase to 14. (j) [Intentionally Deleted]. (k) Notice Addresses: .

With a copy to: Lincoln Harris LLC 5430 Wade Park Boulev Raleigh, North Carolina Attention: David P. Odd Tenant: Paidion Research, Inc. 240 Leigh Farm Road, S Durham, NC 27707 (I) Security Deposit: $26,958.75. (m) Brolcer{s):CERE-Raleigh, LLC Tenant. representing Landlord and Tri (n) Guarantor: N/A. (o) Parking. Tenant shall have the non-exclusive right to use 4 u per 1,000 rentable square feet of the Premises (or portion thereo areas adjacent to the Building which constitutes a p011ion of the C 2. DESCRIPTION OF PREMISES. Landlord hereby leases to Tenant, and Tenant hereby accepts and re Premises within the Building located in the Business Park; together with the none Common Areas. The useable area of the Premises shall be detennined in accor set forth in ANSI 265.1-1996, as promulgated by the Building Owners and ("BOMA Standard"). The rentable area of the Premises shall be determined by area of the Premises by a "core factor" as reasonably determined by Landlord. time, have its architect or engineer measure the actual total square footage of Premises. In the event the Building shall contain an amount of square footage d referenced in Section I (i) above, the Building shall be redefined to reflect the ac Tenant's Propm1ionate Share shall be redefmed to reflect the actual square footag event the Ptemises shall contain an amount of square footage different than th referenced in Section l(a) above, the Ptemises (and all other provisions related t Proportionate Share) shall be redefined to reflect the actual square footage an hereinafter defined) shall be propmtionately adjusted based on the actual square f applicable square foot rental rate. The cost of such measurement shall Notwithstanding anything herein to the contrary, if Landlord has not exercised hereunder within one hundred and eighty (180) days of the date of this Lease, Lan lts rights to such measurement. TERM; COMMENCEMENT DATE; DELIVERY OF PREM 3. (a) Term. Unless otherwise adjusted as hereinbelow provided, the T

event the Commencement Date is a day other than the ftrst day of a calendar m shall be that period commencing on tl1e Commencement Date and continuing un the Adjustment Date and each succeeding Lease Year shall be a twelve-month pe subsequent anniversary of the Adjustment Date. (b) Commencement Date. Notwithstandh1g anything contained he Commencement Date shall be deemed to be the earlier of: (a) the date Tenant, any pmiion of the Premises with Tenant's permission, commences business oper or (b) May!, 2014. (c) Deliverv of Premises. Tenant has made a complete inspection accept ilie Premises and the Building in their "AS IS", "WHERE IS", and condition without recourse to Landlord, subject to Landlord's representations a contained in this Lease. After delivery, except as expressly provided in tl1is Le no obligation to furnish, equip or improve the Premises or the Building. Tena the Premises in accordance with the Workletter attached hereto as Exhibit "C". Notwithstanding the foregoing, Landlord shall use reasonable efforts Tenant's licensed contractors with access to the Premises iliree (3) weeks prio Date for among other thh1gs, Tenant's installation of its furniture, fixtures, cabli the Premises, provided (i) Tenant has obtained all insurance required hereun Tenant, (ii) such early access by Tenant and its contractors does not in any way Landlord or any cuJTent tenant, (iii) Tenant's access to the Premises is coord Landlord, and (iv) Tenant's occupancy of the Premises prior to the Comme complies with all other applicable terms and conditions of this Lease.Such e operate to trigger the "Commencement Date" as provided above. (d) Expansion of the Premises. The parties aclmowledge iliat begi Tenant will sublease Suite 245 fimi:t the cmTent tenant of Suite 245 ("RED" sublease agreement with RED (the "Suite 245 Sublease"). On April 1, 2017, w date the Suite 245 Sublease expires, Suite 245 shall be added to the Premises Suite 245 in its as-is, where-is condition. Until April!, 2017, the term Premis mean Suite 250. Beginning on April 1, 2017, ilie term Premises shall mean both The Minimum Rental table under Section I (g) above reflects the addition of Suit April 1, 2017, subject to a Minhnum Rental abatement period as noted in such tab (e) Contingency. The effectiveness of this Lease is contingent upon Suite 245 St1blease by Tenant and RED, (ii) the execution of Landlord's c Sublease, and (iii) the execution of a lease amendment between RED and Land 250 to Landlord (the "Contingencies"). If any of the Contingencies are not sa days of execution of this Lease, then either party may terminate this Lease with w other party within ftve (5) days of the end of such thirty (30) day period. 4. RENTAL.

(a) Minimum Rental. Beginning with the Commencement Date and continuing through the E termination of this Lease, Tenant shall pay Minimum Rental in accordance with Section l(g) in equal monthly installments each in advance on or before the fir the Commencement Date is a date other than the first day of a calendar month, th be prorated daily from such date to the first day of the next calendar month an Commencement Date. (b) Abated Rent Period. So long as Tenant is not in default under t Tenant aclmowledge that Tenant will receive cettain Minimum Rent abatemen Rental Abatement Periods as noted in the Minimum Rental table in Section l(g). term or covenant required to be performed by Tenant under the Lease beyond a cure period dming the Tenn and as a result the Lease is terminated prior to sch Term, Landlord shall have the right to rescind all such reductions or abat hereunder, and to recover fi·om Tenant as of the termination date of this Lease ( sums recoverable from or payable by Tenant in cotmection therewith) an amoun Minimum Rent which would have been payable during the Minimum Rental Tenant been required to pay for each month thereof the amount of Minimum Re balance of said calendar year, but in no event shall Landlord be entitled to a amounts if included in other damages Landlord receives. (c) Operating and Maintenance Expenses. Tenant shall pay Tenant's Proportionate Share (as set fmth in Section l(i and expenses paid or incurred by Landlord each calendar year in the operation, re the Building, the Common Areas and the Business Park (the "Operating Expen costs exceed the Operating Expense Stop set forth in Section !(h). For pur Expenses shall include without limitation, all: (i) ad valorem taxes (or any tax h thereof) levied on the Premises, the Building, the Common Areas or any im insmance premiums and policy deductibles paid with respect to the Building, inc coverage insurance and liability insurance, (iii) personal propetty taxes applica owned by Landlord and used exclusively for the benefit of the Building or the Pre share of such taxes if such personal prope1ty is also used to benefit other buildi fees or costs incurred in connection with protesting any tax assessment, (v) Sta (as hereinafter defined) including utilities, heat and air conditioning, standar window cleaning, (vi) building management (including management fees not to in the Raleigh/Durham rental market where the Building is located), (vii) tlw cost care m1d general landscaping, irrigation systems, maintenance and repair to pa (including storage of materials), driveways, sidewalks, exterior lighting, garbage snow removal, water and sewer, plumbing, signs and other facilities serving or b the Building, (viii) the cost of all services rendered by third parties with respect Common Areas and all costs paid or incurred by Landlord in providing any of th by Landlord pursuant to the terms of this Lease; (ix) costs of all capital im

Park, including without limitation, the reasonable costs and expenses assoc maintenance and operation of Business Park amenities made available for the com of the tenants of the Business Park fi·om time to time. Landlord shall use good Operating Expenses in line with costs for other similarly situated first Raleigh/Durham market, taking into account rent and other relevant factors. Notwithstanding the foregoing, Common Area Operating Expenses and not include the following: (i) (ii) Leasing commissions. The cost of tenant fir1ish improvements provided solely for the be proposed tenants in the Building. (iii) Costs of correcting building code violations which violations wer Commencement Date. Depreciation on the Building. (iv) (v) (vi) (vii) (viii) The cost of services separately charged to and paid by another ten Interest payments and financing costs associated with Building fi Legal fees associated with the preparation, interpretation and/or e Repairs and replacements for which and to the extent that Landlo by insurance and/or paid pursuant to warranties. Advertising and promotional expenses. Costs representing an1ounts paid to an affiliate of Landlord f which are in excess of the amounts which would have been pai relationship. (ix) (x) Notwithstanding the foregoing, if in any year the Building is less than n occupied, the variable portion of Operating Expenses shall be adjusted to r Operating Expenses which would reasonably be expected to be incurred by Land ninety-five percent (95%) occupied. Notwithstanding the foregoing, in no event Operating Expenses as hereinabove described result in a profit to Landlord. "Additional Rental" shall mean such costs, expenses, charges and oth Tenant Contribution (as defined below), to be made by (or on behalf of) Tenant t party if required under this Lease), whether or not the same be designated as such. (d) Payment of Operating Expenses. Tenant shall pay to Landlord in advance each month commencing on Jan Tenant's installments of Minimum Rental (and Additional Rental, if applicable) Contribution") equal to one-twelfth (1/12) of Tenant's Propmtionate Share of th hereinabove described for any calendar year· (including any applicable pmtial cal such costs exceed the Operating Expense Stop, as estimated by Landlord (in it Landlord will make reasonable efforts to provide Tenant with Landlord' Contribution for the upcoming calendar year on or before December 15 of each Term hereof. Not more than twice during any calendar year, Landlord may in g

calendar year. Tenant shall pay the total amount of any balance due shown o thitty (30) days after its delive1y. In the event such annual costs decrease for shall reimburse Tenant for any overage paid and the monthly rental installments be reduced accordingly, but not below the Minimum RentaLFor the calendar commences, Tenant's Contributionshallbe proratedfrom the Comme December 31 of such year. Fmther, Tenant shall be responsible for the payment for the calendar year in which this Lease expires, prorated fi·om Januruy I thereo Date. Upon the Expiration Date, Landlord may elect either (i) to require Te estit:nated runount within thirty (30) days after the Expiration Date, which est Landlord based upon actual ru1d estimated costs for such year, or (ii) to withh until the exact amount payable by Tenant is determinable, at which time Tena Lai1dlord any deficiencies or Landlord shall return any excess Security Deposit to Notwithstanding the foregoing, the Controllable Operating Expenses which may be passed through to Tenant under this Section 4 shall not increase amount which exceeds seven percent (7%) of such Controllable Operating Expe preceding Lease Year (as measured on a cmnulative and compounded basis) "Controllable Operating Expenses" shall be deemed to include all Operating Exp (e.g., electricity, gas, water ru1d sewer), insurance, taxes, snow removal ru1d ru1y o set or determined by a governmental entity or other third party or are other reasonable control. (e) Docrnnentruy Tax. In the event that any documentary stamp tax, sales tax or any othe (exclusive of aiJY income tax payable by Landlord as a result hereof) becomes leasing or letting of the Premises, whether local, state or federal, and is require execution hereof or otherwise with respect to this Lease or the payments due he shall be borne by Tenant and shall be paid promptly and prior to same becomin provide Landlord with copies of all paid receipts respecting such tax or charge pr same. (f) Late Payment. If any monthly installment of Minimum Rental, Additional Rental (if an ru1d payable pm·sua.J1t to this Lease remains due and unpaid seven (7) days after sa Tenant shall pay as additional rent hereunder a late payment charge equal to fi past due amount. All unpaid rent and other smns of whatever nature owed by T this Lease shall bear interest from the tenth (lOth) day after the due date thereof two percent (2%) per annum above the "prime rate" as published in The Wall Str time (the "Prit:ne Rate") or the maximum interest rate per annum allowed b Landlord of ruw payment from Tenant heretmder in an aJilount less than that wh in no way affect Landlord's rights under this Lease and shall in no way c satisfaction.

structural alterations which do not require a building permit, which do not a electrical systems, and which are not visible from the exterior of the Premises, co Thousand and No/100 Dollars ($5,000.00) ("Cosmetic Changes") in the aggreg year to the Premises without obtaining Landlord's consent, but in such eve Landlord with thirty (30) days prior written notice of such alteration and mu materials and paint. Any other nonstructural changes or other alterations, additi the Premises other than the Cosmetic Changes shall be made by or on behalf of T written consent of Landlord, which consent shall not be umeasonably wit alterations, additions or improvements, including without limitation all pa carpeting, floor and wall coverings and other fixtures (excluding, however, T described in the Section entitled "Trade Fixtures and Equipment" below) made b of Tenant shall, when made, become the prope1ty of Landlord; provided, howeve right, in Landlord's sole discretion, to obligate Tenant to remove said a improvements from the Premises (and restore the Premises to the condition in wh undettaking of said alterations or improvements) at the expiration or earlier tenni Notwithstanding mwthing contained herein to the contrary, all alterat undertaken by Tenant shall be consistent with the then-existing quality, color sche general aesthetic appearance and tenor of the balance of the Building. Fur improvements to the Premises, except the Tenant Improvements which are a whether undertaken by Tenant or Landlord shall be subject to a fee (the "Co Fee"). Tenant agrees to pay Landlord the Construction Mmmgement Fee as follo (a) Five percent (5%) of the total cost of planning and con and improvements if such construction costs exceed Ten Thousand and Noll 00 D (b) and improvements ($10,000.00). Ten percent (I0%) of the total cost of planning and con if such constuction costs are less than Ten Thousan Except as otherwise providedherein, Tenant agrees to pay Lan Management Fee within ten (10) days after receipt of Landlord's invoice therefor. 6. USEOFPREMISES. (a) Tenant shall use the Premises only for general office purposes an Tenant shall comply with all laws, ordinances, orders, regulations and zoning clas governmental authority, agency or other public or private regulatmy authori underwriters or rating bureaus) having jurisdiction over the Premises.Tenant follow any practice relating to the Premises, the Building or the Common Areas nuisance or detract in any way from the reputation of the Building as a first-class comparable to other comparable buildings h1 the Raleigh/Durham market takin other relevant factors. Tenant's duties in this regard shall include allowing no nox fmnes, gases, smoke, dust, steam or vapors, or any loud or disturbing noise or vib

Premises shall not be used for the treatment, storage, transportation to or from, u hazardous wastes, materials, or substances, or any other substance that is prohib by any governmental or quasi-govemmental authOiity or that, even if not so regu a hazard to health and safety of the occupants of the Building or sunoundi "Hazardous Substances"). In addition, Tenant shall be liable for, and shall inde hann[ess from, all costs, damages and expenses (including reasonable attm connection with the use, storage, discharge or disposal of any Hazardous Subst Building by Tenant or Tenant's Invitees. (c) Tenant shall exercise due care in its use and occupancy of th commit or allow waste to be committed on any portion of the Premises. Tena Premises, and the Tenant Improvements and other Alterations (hereinafter define repair and condition during the Term at Tenant's sole cost and expense, and Ten or other termination of the Term, su!1'ender and deliver the same and all keys, corn1ected therewith (excepting only Tenant's personal property) in good order, the same shall be at the Commencement Date, except as repaired, rebuilt, resto pursuant to this Lease, and except fot·ordinary wear and tear. Landlord shall hav to make any repairs in or to the Premises, the Tenant Improvements or any Altera provided in this Lease. Any and all dan1age or injury to the Premises (includin Tenant Improvements), or the Building caused by Tenant, or by any empl assignee, subtenant, invitee or customer of Tenant shall be promptly reported to the mutual waiver of claims and subrogation contained in this Lease, repaired b cost; provided, however, that Landlord shall have the option of repairing any suc Tenant shall reimburse Landlord for all costs incurred by Landlord in respect th within fifteen (15) days after Tenant receives Landlord's notice of such costs. (d) Tenant's use and occupancy oftl1e Premises shall include the us entitled thereto of the Common Areas and all other improvements provided by L use of the Building tenants, and any other common facility as may be designated Landlord, subject, however, to the terms and conditions of this Lease and to t regulations for use therefor as prescribed from time to time by the Landlord. Su Tenant, its employees, agents, customers and invitees shall have the nonexclusi other benefiting tenants) to use the Common Areas for purposes intended and the adjacent sutface parking areas in accordance with Section l(o) herein.Tena materially interfere with the use of the Common Areas by Landlord, another te entitled to use the same. Landlord reserves the right, from time to time, to al Areas, to exercise control and management of the same, and to establish, mod such reasonable rules and regulations as Landlord in its discretion may management of the Building or the Common Areas, provided, however, Landl efforts to minimize any adverse affect on Tenant's use and enjoyment of Landlord's work. (e) Tenant shall not block or cover any of the heating, ventilation or the Premises. Tenant shall keep all ice and coffee machines that Tenant places

Landlord in writing of: (i) any visible signs of mildew or mold growth in the P becomes aware; and (ii) any Mold and Mildew Conditions discovered by Tenant (f) Tenant shall save Landlord and its partners or members har liabilities, penalties, fines, costs, expenses or damages resulting from the failure o the provisions of this Section 6, provided, however, Tenant shall not be respons conditions. This indemnification shall survive the termination or expiration of th 7. SERVICES BY LANDLORD. Provided that Tenant has fully complied with all tenns and conditions then in default hereunder, Landlord shall cause to be fumished to the Premises (s as part of the Operating Expenses) in coll1ll1on with other tenants during "Stand (as defined below), Monday through Friday and Saturday (excluding holidays) janitorial services (once per working day after normal weekday working hours) city mains for drinking, lavatoty and toilet purposes and, to the extent Tenant pro · interior kitchenette area; operatorless elevator service; electricity for general of fluorescent lighting replacements to building standard fixtures only); trash rem city schedules; and heating and air conditioning for reasonably comfortable u Premises (but in any event within tl1e temperature ranges required by Section heating and cooling conforming to any governmental regulation prescribing lim deemed to comply with this service. All additional costs resulting from Tenant heating, air conditioning or electricity shall be paid by Tenant, but Tenant shall n unusual demands for any of the foregoing without Landlord's prior written cons withhold if it reasonably detennines that such equipment may not be safely use electrical service is not adequate therefor. Notwithstru1ding anything containe Lru1dlord reserves the right to contract with ruty third party provider of such services to the Premises, the Building and the Business Park in the most econom shall not contract with any other third party provider to supply such utilities Landlord's prior written consent. So long as Landlord acts reasonably and in goo abatement or reduction of reut by reason of any of the foregoing services not bein to Tenant. Landlord agrees to provide heating ru1d air conditioning after-hours (i.e,, Standard Hours of Operation) at Tenant's request after reasonable notice and if zoned for this purpose. The cost of after-hours service of heating or air conditi rent payable monthly by Tenant at $35.00 per m1it per hom. As used herein, "Standru·d Hours of Operation" shall mean and refer to th the Building which are 8:00 a.m. to 6:00p.m. Monday through Friday and 9:00a. Saturday, except holidays. Holidays shall mean and refer to each of the follow aside for observance): New Year's Day, Memorial Day, Independence Day, L Day, Christmas Day and any other holiday(s) generally recognized as such by lan the Raleigh/Dmham Area office mru·ket, as reasonably detennined by Landlord a

8. TAXES ON LEASE AND TENANT'S PROPERTY. (a) Tenant shall pay any taxes, documentary stamps or assessments be imposed or assessed upon this Lease, Tenant's occupancy of the Premises or equipment, machinery, inventory, merchandise or other personal property locat owned by or in the custody of Tenant as promptly as all such taxes or assessme payable without any delinquency. (b) Landlord shall pay, subject to reimbursement from Tenant as entitled "Rental" of tlus Lease, all ad valorem property taxes which are now or the Building, the Premises and the Common Areas, except as otherwise expressly 9. INSURANCE AND INDEMNITY. (a) reimbursement Fire and Extended Coverage Insurance. Landlord shall maint by Tenant as provided in Section 4 hereof, for fire and casualt insurance, with extended coverage (including boiler and machine1y coverage) equal to the full replacement cost thereof. Tenant shall not do or cause to b Premises or in the Building anything deemed extrahazardous on account of fire the Premises, the Common Areas or the Building in any matmer which will premium rate for any insurance in effect on the Building or a part thereof. If, be done, caused to be done, permitted or omitted by Tenant or Tenant's Invitees, t kind of insurance in effect on the Building or any patt thereof shall be raised, Te on demand the amount of any such increase in premium which Lat1dlord shall pa if Landlord shall demand that Tenant remedy the condition which caused a insmance premium rate, Tenant shall remedy such condition within five (5) d demand. Tenant shall maintain and pay for all fn·e and extended coverage insura Premises, including trade fixtures, equipment, machine1y, merchandise or belonging to or in the custody of Tenant.Tenant shall first furnish to Landl policies or certificates of insurance evidencing the required coverage prior to th and thereafter prior to each policy renewal date. Notwithstanding anything herein to the contraty, Landlord reserves the ri and assigns to self-insure against any risk required here1mder to be insured o Landlord so long as any such program of self-insurance affords the same cover which would be afforded in tl1e event Landlord procured insurance fi·om a third-p (b) Liability Insmance. At all times during the term of this Lease, cost and expense, keep in force adequate public liability insurance under the general liability policy (occurrence coverage) insuring Tenant against at1y liabil occupat1cy or maintenance of the Premises or the business operations of Tenant in the amount of not less than Three Million and No/100 Dollars ($3,000,000.0 company(ies) licensed to do business in Nmth Carolina and as shall fi·om tim acceptable to Landlord (and to atly lender having a mortgage interest in the Landlord and its members or partners at1d Landlord's agent as an additional insu

rated A-X or better in the most current issue of Best's Insurance Repmts and s $25,000.00 or less.Such insurance shall include, without limitation, persona liability coverage for the perfonnance by Tenant of the indemnity agreements Tenant shall first furnish to Landlord copies of policies or ce1tificates of i required coverage prior to the Commencement Date and thereafter prior to ea Tenant shall use commercially reasonable efforts to cause all policies required contain a provision whereby the insurer is not allowed to cancel or change without first giving thirty (30) days' written notice to Landlord, but failure of suc provisions shall not be a default hereunder. (c) Indemnity. Subject to the mutual waiver of subrogation set f indemnify and save Landlord and its members or partners harmless against any claims, suits, demands, actions, fines, damages, and liabilities, and all cost (including without limitation reasonable attorneys' fees) attributable to (i) any performance of any obligation of Tenant hereunder, (ii) Tenant's use or occup (iii) otherwise arising out of injmy to persons (including death) or prope11y occ arising out of the Premises or other areas in the Building if caused or occasioned act or omission of Tenant or Tenm1t's Invitees, except to the extent caused by willful misconduct of Landlord. The non-prevailing party shall also pay reasonable attorneys' fees that may be incurred by the prevailing pa1ty in enforci Lease, whether incuned as a result of litigation or otherwise.Tenant shall g notice of any such happening causing injury to persons or propei1y. Except if caused by any act(s) or omission(s) of Tenant or Tenant's In mutual waiver of subrogation set fmth herein, Landlord shall indemnify, defend m against any and all actual and direct claims, suits, demands, actions, fines, damag costs and expenses thereof (including without limitation reasonable attorneys' fe to persons (including death) or prope11y occurring in, on or about, the Cmrunon A Business Park if directly caused or occasioned wholly or in part by any negligen of Landlord or Landlord's agents, employees or contractors. Provided, howeve liable for any damage caused or occasioned by or fi·om water, snow or ice being the roof, trapdoor, walls, windows, doors, or otl1erwise in, upon or about the Pre from any damage arising from acts or omissions of co-tenants or other occupan Business Parle (d) Landlord Insurance. Landlord shall keep in force during the term in such amounts and coverages as Lm1dlord deems appropriate or is otherwise third pmties, such as its lender. 10. LANDLORD'S COVENANT TO REPAIR AND REPLACE. (a) the Common During tl1e Term, Landlord shall be responsible for necessmy re Areas as well as the roof and the base building structmal comp including without limitation, the central plumbing and electrical systems serving

not materially or adversely impair Tenant's use and enjoyment of the Premises danger to the health or safety of Tenant or· Tenant's Invitees. Landlord's r (excluding any restoration obligations following a casualty pursuant to the ter shall be made as soon as reasonably possible using due diligence and reaso account in each instance all circumstances smrounding the repair or replac limitation, the materiality of the repair or replacement to Tenant's use and operat the Premises and the relation thereof to the enjoyment of same, such period no receiving written notice from Tenant of the need for repairs or such longer perio necessary under the circumstances so long as Landlord is diligently pursuing provided, however, in no event shall such period of time exceed I 20 days after from Tenant. If Landlord carmot, using due diligence, complete its repairs with specified and such failure to repair has a material adverse impact on Tenant's Premises, then (unless the need for such repairs or replacements is the r misconduct or acts or omissions of Tenant or Tenant's Invitees, in which ev entitled to any remedy) Tenar1t may tenninate this Lease effective upon tl1irty notice to Landlord, without prejudice to Landlord's rights to receive payment fr dan1ages to the extent caused by Tenant or Tenant's Invitees. lfthe need for suc is the result of the negligence, misconduct or acts or omissions of Tenant or T expense of such repairs or replacements are not fully covered and paid by La Tenant shall pay Landlord the full amount of expenses not covered. (b) Landlord shall not be liable for any failure to make any re maintenance required of Landlord hereunder unless such failme shall persist fo of time after written notice from Tenant setting forth the need for such repai reasonable detail has been received by Lar1dlord. Except as set forth in the Secti "Damage or Des1TUction of Premises," there shall be no abatement of rent. The Landlord by reason of any injury to or interference witl1 Tenant's business arising repairs, replacements, alterations or improvements to any portion of the Buildin fixtures, appurtenar1ces and equipment therein except to the extent caused dire negligence or willful misconduct. To the extent permitted under applicable law to make repairs at Landlord's expense under any law, statute or ordinance now or 11. PROPERTY OF TENANT, All property placed on the Premises by, at the direction of, or with th Tenant's Invitees, shall be at the risk of Tenant or the owner thereof ar1d Landlo any loss of or damage to said property resulting fi·om any cause whatsoever ex loss or damage caused by the gross negligence or willful misconduct of Landlor same is not covered by the insurance Tenant is required to maintain under t!1e ter 12. TRADE FIXTURES AND EQUIPMENT. Any trade fixtures and equipment installed in the Premises at Tenant's e Tenant in notice to Landlord shall remain Tenar1t's personal property and Tena

thereto, or (ii) be subject to Landlord's removing such property from the Premise Tenant's expense and without any recourse against Landlord with respect there generality of the foregoing, the following property shall in no event be deemed t Tenant shall not remove any such property from the Premises under any circ whether installed by Landlord or Tenant: (a) any air conditioning, air ventilati equipment; (b) any lighting fixtures or equipment; (c) any carpeting or other pe (d) any paneling or other wall coverings; (e) plumbing fixtures and equipment; or 13. DAMAGE OR DESTRUCTION OF PREMISES. If the Premises are damaged by fire or other casualty, but are not re Tenant's business, either in whole or in pali, in Tenant's reasonable determinati such damage to be repaired without unreasonable delay and the Annual Renta reason, in Tenant's reasonable determination, of such casualty the Premises are r Tenant's business, either in whole or in pali, Landlord shall cause the damage to the Building (including any Tenant Improvements or Alterations therein to Landlord) to be repaired or replaced without unreasonable delay, and, in the int shall be proportionately reduced as to such portion of the Premises as is rendered abatement of rent shall not, however, create an extension of the Term. Provided, such casualty, the Premises are rendered untenantable in some material porti reasonable estimation, determines that the amount of time required to repair diligence is in excess of two btmdred ten (210) days (as measured fi·om the is building permits necessary for the reconstruction of the Building), then either pa terminate this Lease by giving written notice of termination within tbilty (3 0 casualty, and the Annual Rental shall (i) abate as of the date of such casualty in the Premises rendered untenantable and (ii) abate entirely as oftl1e effective date Lease. Notwithstanding the foregoing, in the event the casualty giving rise to a caused by the negligence, misconduct or acts or omissions of Tenant or Tenan have no right to terminate this Lease. Notwithstanding the other provisions of t there should be a material casualty loss to the Premises during the last Lease Ye may, at its option, terminate this Lease by giving written notice to Tenant within date of the casualty and the Annual Rental shall abate as of the date of such no herein, Landlord slmll have no obligation to rebuild or repair in case of fire o termination under this Section shall affect any rights of Landlord or Tenant he prior defaults of the other pru·ty. Tenant shall give Lru1dlord immediate not casualty in the Premises. Notwithstanding anything contained in this Section t shall only be obligated to restore the Premises to the condition as existed on t unless Tenant makes available to Landlord proceeds fi·om Tenant's insurance restore the Premises to the condition in which it existed immediately prior to those items in excess of building standru·d. h1 ru1y event, Landlord shall not be fi.mds than the amount received by Landlord from the proceeds of any insu received from Tenru1t, provided, however, if Landlord's insurance proceeds are in or complete the restoration work required of Landlord hereunder and Lan additional funds to complete the work, then Tenant may tenninate the Lease.

requirements of any legally constituted public authority that may be in effect f necessary by reason of Tenant's specific use or occupancy of the Premises. La promptly with any such requirements if not made necessary by reason of Ten With regard to the physical structure of the Building, Landlord agrees to use goo to unde1take those actions that are "readily achievable" (as such term is defined attempt to bring the physical structure of the Building in compliance with the ap the ADA in effect as of the Commencement Date. If it is determined that for an have failed to cause the physical structure of the Building to be brought into com ofthe Commencement Date (to at least the minimum extent required under appli effect), then Landlord, as its sole obligation and at its sole expense (which may b ·Expenses to the extent pennitted by Section 4(c)), will take tl1e action(s) necess structure of the Building (excluding any tenant improvements or alterations) to acknowledges and agrees that Landlord has and shall have no other obligation o Tenant, or to anyone claiming by or through Tenant, regarding any failure activities therein to comply with the applicable requirements of the ADA. N contained herein to the contrary, it is agreed that: (a) Tenant is exclusively respo with all requirements of any legally constituted public authority in the event non-design of the interior of the Premises pursuant to the Plans or Tenant's specific us the event of any non-compliance for wl1ich Landlord is responsible, Landlord breach of this Lease if such non-compliance does not materially impair Tenan from, the Premises or threaten or endanger the health or safety of Tenant or Tena 15. MUTUAL WAIVER OF SUBROGATION. For the pmpose of waiver of subrogation, the parties mutually release and rights to claim damages, costs or expenses for any injury to propetty caused by matter whatsoever in, on or about the Premises if the amount of such damage, c paid to such damaged party tmder the terms of any policy of insurance or woul injured party had catTied the insurance required of it hereunder. All insuran respect to this Lease, if permitted under applicable law and if agreed by the i contain a provision whereby the insurer waives, prior to loss, all rights of su Landlord or Tenant. 16. SIGNS AND ADVERTISING. Landlord shall install, at Landlord's sole cost and expense, the initial tena in accordance with building standards at or near the suite entrance to the Premi located in the lobby of the Building. Any additional signage or replacement or signage shall be at Tenant's sole cost and expense. In order to provide architectural control for the Building and the Busines install any exterior signs, marquees, billboards, outside lighting fixtures and/or Building, the Premises or the Common Areas. Landlord shall have the right to r other decoration restore fully the Building, the Premises or the Common Areas at of Tenant if any such exterior work is done without Landlord's prior written a

Tenant may install, at Tenant's sole cost and expense, tenant ide monument sign for the Building in a location detennined by Landlord in a standards and subject to any applicable governmental laws or regulations (the "M shall maintain the Monument Sign at Tenant's sole cost and expense. At the e removal of the Monument Sign Tenant shall pay all costs to remove the Monume damage caused. Additionally, Tenant shall have the right, at its expense, to crea the glass door at the entrance to the Premises in accordance with plans approved Landlord. 17. LANDLORD'S RIGHT OF ENTRY. Landlord, and those persons authorized by it, shall have tl1e right to e reasonable times and upon twenty-four hours advance notice (except in the ev which case notice is not required) for the purposes of making repairs, makin utilities, providing services to the Premises or for any otl1er tenant, making ins same to prospective purchasers, lenders or prospective tenants (during the la Term), as well as at any time without notice in the event of emergency invo propetty or persons in or around the Premises or the Building, provided, how Landlord will use its commercially reasonable efforts to minimize any interferen mjjoyment ofthe Premises, by reason of such entry. 18. INTENTIONALLY OMITTED. 19. EMINENT DOMAIN. If any substantial portion of the Premises or of the parking lot is ta eminent domain (including any conveyance made in lieu thereof) or if such takin the normal operation of Tenant's business, then either party shall have the right t giving written notice of such termination within thirty (30) days after such takin to terminate this Lease, Landlord shall repair and restore the Premises to the condition (but only to the extent of any condemnation proceeds made availab Annual Rental shall be proportionately and equitably reduced as of the date oftl not able to or does not fully restore the Premises in the same manner and timefr 13 hereof witl1 respect to casualty events, Tenant may terminate this Lease. Al for any taking (or the proceeds of a private sale in lieu thereof) shall be the prope such award is for compensation for damages to the Landlord's or Tenant's inte Tenant hereby assigns all of its interest in any such award to Landlord; provided, not have any interest in any separate award made to Tenant for loss of business taking of Tenant's trade fixtnres or equipment if a separate award for such item such separate award does not reduce the award to Landlord. Notwithstanding tl shall Tenant be entitled to any compensation for the loss of its leasehold estate. 20. EVENTS OF DEFAULT AND REMEDffiS. (a) Upon the occurrence of any one or more of the following events

failure is deemed an "Event of Default" only one (1) time in any tw period); (ii) Tenant's failure to perform any other of the terms, contained in this Lease if not remedied within thirty (30) days after thereof, or if such default cannot be remedied within such period, Tena (30) days after written notice thereof commence such act or acts as shal the default and shall not thereafter diligently prosecute such cure and c within ninety (90) days after written notice thereof: (iii) Tenant shall become bankrupt or insolvent, or file any d pursuant to any statute a petition in bankruptcy or insolvency or for petition for the appointment of a receiver or trustee for all or substantia and such petition or appointment shall not have been set aside within n date of such petition or appointment, or if Tenant makes an assign creditors, or petitions for or enters into a similar atTangement; or (iv) A default by Tenant under any other lease heretofor Tenant for any other space in the Business Parle. (b) In addition to its other remedies, Landlord, upon an Event of have the immediate right, after any applicable grace period expressed herein, to t Lease and/or terminate Tenant's right of possession and reenter pursuant to su and remove all persons and properties fi·om the Premises and dispose of such pm without being guilty of trespass or being liable for any damages caused thereby. Premises, it may either te1minate this Lease or, fi:om time to time without tenninate Tenant's right of possession and make such repairs as may be necessa the Premises and relet the Premises upon such tetms and conditions as Landlord any responsibility on Landlord whatsoever to account to Tenant for any surp retaking of possession of the Premises by Landlord shall be deemed as an electio unless a written notice of such intention is given by Landlord to Tenant at t notwithstanding any such reentty or reletting without termination, Landlord ma elect to tenninate for such previous default. In the event of an elected terminati before or after reenny, Landlord may recover from Tenant damages, including th Premises and any reasonable and customary costs incurred in reletting the Pre remain liable to Landlord for the total Annual Rental (which may at Landlord's e be due and payable in full as of the Event of Default and recoverable as d discounted to present value at 5% per atmum) as would have been payable by remainder of the term less the rentals actually received fi·om any reletting or, at the reasonable rental value of the Premises for the remainder of the term. In Rental which would be payable by Tenant subsequent to default, except with res (which shall be calculated in accordance with Section !(g) hereof), the Annua Year of the unexpired term shall be equal to the Annual Rental payable by Tena prior to the default. If any rent owing under this Lease is collected by or thro

21. SUBORDINATION. This Lease is subject and subordinate to any and all mortgages or deeds on the property of which the Premises is a pmt, and tl1is clause shall be self-oper instrument necessary to effect such subordination; however, if requested by promptly execute and deliver to Landlord IDlY such certificate(s) in a commerc Landlord may reasonably request evidencing the subordination of this Lease to, Lease as additional security for, such mortgages or deeds of trust. Subject to tl1e Landlord provide Tenant with a non-disturbance agreement in a commercially re Tenant from any mortgagee, trustee or beneficiary, this Lease shall be subject mmtgage or deed of tmst which may hereafter encumber the propeJty of whic Tenant's obligations under this Lease shall continue in full force and effect n default proceedings under a mortgage or deed of trust and shall attom to th beneficiary of such mmtgage or deed oftmst, and their successors or assigns, an any foreclosure or default proceedings. Tenm1t will, upon request by Landlor Landlord or to any other person designated by Landlord, any instmment or instru reasonable form required to give effect to the provisions of this Section. ASSIGNMENT AND SUBLETTING. 22-Tenant shall not assign, sublet, mmtgage, pledge or encumber this Lea interest in the whole or in any poJtion thereof, directly or indirectly, without tl1e Landlord, which consent shall not be unreasonably withheld, conditioned, or dela assignment, sublease, mmtgage, pledge or encUlllbrance, Tenant shall: (i) remain petformance of all terms of this Lease, (ii) pay all reasonable costs incmred by with such assignment, sublease or mmtgage, including without limitation, attom exceed $1,500.00 so long as Tenant utilizes Landlord's standard fmm withou changes, and (iii) pay to Landlord one-half of any rental or any fees or charge excess of the Annual Rental payable to Landlord hereunder as futther renta deducting Tenant's actual and reasonable costs incurred in connection with such Landlord's consent to one assignment or sublease will not waive the requirem subsequent assignment or sublease as required herein. Any attempted assignme in violation of the terms and conditions of this numbered Section 22 shall be nul to Landlord of a proposed sublease or assignment of all or any portion of the Space"), Landlord shall have the option, within fifteen (15) days after its re terminate this Lease with respect to the Proposed Space, whereupon the pmti fmther rights or liabilities with respect to the Proposed Space except as othe herein and ui1less Tenant within ten (I0) days of receipt of Landlord's notice Proposed Space rescinds its request for such consent. In the event of a proposed assignment of this Lease or subletting of all o Tenm1t shall submit to Lm1dlord, in writing, (i) the uame of the proposed as current financial statements available to Tenant disclosing the financial co assignee or subtenant, (iii) the nature of the business of tl1e proposed assign

assignment or sublease in writing. Tenant shall promptly deliver a copy of the f or sublease to Landlord upon its receipt of same. Notwithstanding anytl1ing in this Lease to the contrary, Tenant further ag or sublease shall be subject to the following additional limitations: (i) in no even Lease or sublet all or any portion of the Premises to an existing Tenant of subtenant or assignee (unless Landlord consents to such assignment or sublease) proposed subtenant or assignee be a person or entity with whom Landlord or its to or from whom Landlord, or its agent, has given or received any written propo months regal'ding a lease of space in the Business Pal'k; and (iii) Tenant shall n mte for which Tenant is willing to sublet the Premises; and all public adve1tisem the Lease Ol' sublet of the Premises, or any portion thereof, shall be subject to Landlord, such approval not to be umeasotJably withheld or delayed. Said p include, but not be limited to, the placement or display of any signs or letteri Premises or on the glass or any window or door of the Premises or in the interi visible from the exterior. Notwithstanding the conditions set forth in Section 22 of the Lease, Tena (30) days advance written notice to Landlord (but without Landlord's consent), an entity into or with which Tenant is merged or consolidated or to which sub assets or stock are transferred, provided such merger or transfer of assets or stock purpose of transfen·ing the leasehold estate created by this Lease, and provided shall have a net wortl1 of not less than Tenant's net worth on the Commenceme tl1at controls Tenant or is controlled by Tenant or is under common control remains primarily liable after such assignment (either of (i) or (ii) being referre Assignee"). Tenant shall notify Landlord at least tlilrty (30) days before consu111tnated and furnish to Landlord docmnentation that such assignee qualifi hereunder. The term "control" as used in this paragraph shall mean ownership outstanding capital stock of that corporation and control over the management of 23. LANDLORD DEFAULT. In the event of any default by Landlord under this Lease, Tenant will giv specifying such default with patticularity, a11d Landlord shall thereupon have t longer peliod as may be required in the exercise of due diligence) in which to c the event Landlord's cure of any default will take longer than ninety (90) day Tenant with a timeline for the completion of such cure. Unless and until Land default after such notice, Tenant shall not have any remedy or cause of action obligations of Landlord hereunder will be construed as covenants, not condition other provisions of this Lease to the contrmy, Tenm1t shall look solely to Building, and not to any other or separate business or non-business assets of L member, shareholder, officers or representative of Landlord, for the satisfaction Tenant against Landlord, and if Landlord shall fail to pe1form any covenant, t Lease upon Landlord's part to be performed, and as a consequence of such defau

24. TRANSFER OF LANDLORD'S INTEREST. If Landlord shall sell, assign or transfer all or any pmi of its interest i Lease to a successor in interest which expressly assumes all the obligations of L accrue prior to or after such transfer, then Landlord shall thereupon be release covenants and obligations hereunder, and Tenant shall look solely to such s performance of all of Landlord's obligations and such successor shall be obl Landlord's obligations under this Lease.Tenant's obligations under this Leas affected by Landlmd's sale, assignment, or transfer of all or any part of such int Tenant shall thereafter attorn and look solely to such successor in interest as the L 25. COVENANT OF QUIET ENJOYMENT. Landlord represents that it has full right and authority to lease the Pr peacefully and quietly hold and enjoy the Premises for the full Term hereof Default occurs and is continuing hereunder. 26. ESTOPPEL CERTIFICATES. Within ten (10) business days after a request by Landlord, Tenant shall d ce1tificate, in form supplied by or acceptable to Landlord, certifYing any facts respect to this Lease, including without limitation that this Lease is in full force of Default exists on the pmi of Landlord or Tenm1t, that Tenant is in poss commenced the payment of rent, and that Tenant claims no defenses or offsets wi rentals under this Lease. In the event Tenant fails to provide such an estoppel above then all items noted in the estoppel shall be deemed confirmed by Tenant on such estoppel as being corr-ectWithin thirty (30) days after a request by deliver to Tenant a similar estoppel celiificate as noted above covering such m required by Tenant. 27. PROTECTION AGAINST LIENS. Tenant shall do all things necessm-y to prevent the filing of any mech other types of liens whatsoever, against all or any part of the Premises by reason against, through or under Tenant. If any such lien is filed against the Premises, the same to be dischm·ged of record within twenty (20) days after Tenant has Tenant in its discretion and in good faith determines that such lien should be c such security as may be necessm-y to prevent any foreclosure proceedings against pendency of such contest. If Tenant shall fail to discharge such lien within sa furnish such security, then Landlord may at its election, in addition to any other r to it, discharge the lien by paying the amount claimed to be due or by procming security or in such other mmmer as may be allowed by law. If Landlord acts to lien then Tenant shall immediately reimburse Landlord for all sums paid and (including reasonable attorneys' fees) incurred by Landlord involving such lien t the total expenses and costs at an interest rate equal to the Prime Rate plus five pe 28. MEMORANDUM OF LEASE.

the Tenn expires, an instrument in such form acknowledging the fact and date of shall not be recorded. 29. FORCE MAJEURE. In the event Landlord or Tenant shall be delayed, hindered or prevented any act required hereunder, by reason of govenunental restrictions, scarcity of la fire, or any other reasons beyond its reasonable control, the perfmmance of such the period of delay, and the period for performance of any such act shall be e complete performance after the delay period. However, the provisions ofthis S applicable to a party's obligations to pay Annual Rental or any other sums, m expenses required by this Lease. 30. REMEDIES CUMULATIVE--NONWAIVER. Unless otherwise specified in this Lease, no remedy of Landlord or Te exclusive of any other remedy, but each shall be distinct, separate and cumula remedies. Each remedy available under this Lease or at law or in equity may be Tenant fi·om time to time as often as the need may arise. No course of dealin Tenant or any delay or omission of Landlord or Tenant in exercising any rig party's default shall impair such right or be construed to be a waiver of a default. 31. HOLDING OVER. If Tenant remains in possession of the Premises or any part thereof af Term, without Landlord's acquiescence, Tenant shall be deemed only a tenant a no renewal of this Lease without a written agreement signed by both pruties speci "monthly" rental payable by Tenant during any such tenancy at will period sh percent (150%) of the monthly installments of Annual Rental payable durin immediately preceding such expiration. Tenant shall also remain liable for any and consequential, suffered by Landlord as a result of any holdover without Lru1d NOTICES. 32. Any notice allowed or required by this Lease shall be deemed to have b the same shall be in writing and placed in the United States mail, via certified retum receipt requested, with proper postage prepaid or delivered by a national comier and addressed to the appt:opriate party at the address set forth in Section I The addresses of Landlord and Tenant and the party, if any, to whose atte same shall be directed may be changed or added from time to time by either p other in the prescribed manner. LEASING COMMISSION. 33. Landlord and Tenant represent and warrant eacl1 to the otl1er that they broker(s) or any other person claiming any entitlement to any commission transaction except the Broker(s) set forth in Section I (m) hereof. Tenant agree

agrees to indemnifY and save Tenant harmless fi·om and against any and all claim judgments and expenses, .including reasonable attorneys' fees, for any leasin commissions, fees, charges or payments resulting from or arising out of its action Lease. Landlord agrees to be responsible for the leasing commission due Brok written agreement between Landlord and Broker, and to hold Tenant harmless res 34. MISCELLANEOUS. (a) Rules and Regulations. Landlord shall have the right from time to time to prescribe reasonable r "Rules and Regulations") for Tenant's use of the Premises and the Building. current Rules and Regulations respecting the Premises and the Building is attach Tenant shall abide by and actively enforce on all Tenant's Invitees such regul limitation rules governing parking of vehicles in designated areas and during desi (b) Evidence of Authoritv. If requested by Landlord, Tenant shall fumish appropriate legal docum valid existence and good standing of Tenant and the authority of any parties sig Tenant. (c) Nature and Extent of Agreement. Tllis Lease, together witi1 all exhibits hereto, contains ti1e complete a concerning the subject matter, and ti1ere are no oral or written understandi agreements pe1taining thereto which have not been incorporated herein.Thi relationship of landlord and tenant between the parties, and nothing herein shall i any powers, obligations or restdctions not expressed herein. This Lease shall be by the laws of the state in which the Premises are located. (d) Binding Effect. This Lease shall be binding upon and shall inm-e to ti1e benefit of the respective heirs, successors and assigns. This Lease shall not be binding on La an authorized signatory of Landlord and delivered to Tenant. No amendment Lease shall be binding upon Landlord unless same is in writing and executed by ofLandlord. (e) Captions and Headings. The captiollS and headings in this Lease are for convenience and referen no way be held to explain, modifY, or construe tile meaning of tile terms of this Le (f) Lease Review. The submission of ti1is Lease to Tenant for review does not constitute a for the Premises, and this Lease shall become effective as a contract only upon e

(g) Prevailing Pattv. If either Landlord or Tenant places in the hm1ds of an attomey the enfo any portion thereof, for the collection of any rent due or to become due hereu possession of the Premises, Ol' file suit upon same, the non-prevailing (or defau other party reasonable attomey's fees and court costs. (h) Security Deposit. Tenant has paid to Landlord upon sigt1ing this Lease the Security Depos I (I) as security for Tenant's perfmmance of all obligations herennder. The Secu by Landlord in such manner as it shall elect and Landlord shall be entitled to an on the Deposit. In the event of a default by Tenant not cured within the notice a herein, Landlord may, at its option, apply all or any patt of the Security Deposi thereupon Tenatlt shall promptly redeposit with Landlord the ammmt so applie will always have the full Security Deposit on hand during the term of this Lease following the expiration or earlier termination of this Lease, provided that hereunder, Lat!dlord shall refund to Tenant any offue remaining balance of the to final adjustments for payment of any rental required by this Lease. If the B shall have the right to transfer the Security Deposit to the new owner, and upon assumption of the obligations for the Security Deposit required by this Lease, Lan released fi·om all liability for such Security Deposit, and Tenant thereafter sh owner for such Security Deposit. The terms hereof shall apply to evety transfer o (i) Intentioually deleted. Q) Representations and Warranties. The person or persons executing this Lease on behalf of Tenant represe to Landlord as of the date Teuantexecutes and delivers tl1is Lease that: (a) Tena good standing and qualified to do business in the State of Nmth Cm·olina, corporate taxes (if applicable), (c) Tenant will file when due all fonns, reports, f necessaty to comply with applicable laws, and (d) the signatories signing on b requisite authority to bind Tenant pursuant to Tenant's organizati.onal doc agreement, operating agreement or bylaws) or a ce1tified copy of a resolution same. (k) Building Access. There shall be open access to the Building during Standard Hours defined). At all other times, access to the Building shall be restricted by use o system at all entrances to the Building. Landlord shall, furnish Tenant on or bef Date, at no cost to Tenant, up to four (4) access cards or keys per 1,000 rentable Tenant (as of the Commencement Date) as requested by Tenant for entering tl1e hereof, any such access cards, keys or other comparable access devices are co "access cards." Thereafter, additional access cards and replacement access card shall be made available to Tenant at a charge equal to $15.00 per card (subject by Landlord from time to time) upon Landlord's receipt of an order signed

Landlord's written permission and locks on any interior door shall be peimitted locks are permissible under applicable laws and relevant insurance requirement this Lease, Tenant shall surrender to Landlord all access cards and keys related t to Landlord the combination of all locks for safes, safe cabinets and vault doors Premises and in the event Tenant fails to return all such access cards to Landlord Tenant shall pay Landlord $15.00 for each such access card not returned to Landl (1) Financial Disclosures. Tenant shall at any time upon receipt o Landlord (such request to be made no more than twice in any Lease Year), pro accurate fmancial information and documentation about itself and any Guaranto (10) business days after such request. The individuals executing this Lease on represent and warrant to Landlord that the financial statements and other in Landlord by Tenant prior to the execution hereof are true, complete and acc accordance with generally accepted accounting principles applied on a consiste reflect Tenant's net worth as of the date hereof. Landlord covenants and agre confidential; provided, however, Landlord may share the infmmation contained its legal counsel, accountants and employees, prospective pmchasers and lenders requires such parties to be bound by the confidentiality provisions herein, an required by applicable law. . (m) Intentionally omitted. (n) OFAC Compliance. Tenant represents and warrants that (a) Tenant and each person or enti Tenant is (i) not currently identified on the Specially Designated Nationals an maintained by the Office of Foreign Assets Control, Department of the Treasury ( other similar list maintained by OFAC pursuant to any authorizing statute, exec (collectively, the "List"), and (ii) not a person or entity with whom a citizen prohibited to engage in transactions by any trade embargo, economic sanction, United States law, regulation, or Executive Order of the President of the United funds o1· other assets of Tenant constitute prope1ty of, or are beneficially owned, d any Embargoed Person (as hereinafter defined), (c) no Embargoed Person has an whatsoever in Tenant (whether directly or indirectly), (d) none of the funds of T from any unlawful activity witl1the i·esult that the investment in Tenant is prohi Lease is in violation oflaw, and (e) Tenant has implemented procedures, and will procedures, to ensure the foregoing representations and· wal1'anties remain true The term "Embargoed Person" means any person, entity or government subj under U.S. law, including but not limited to, the International Emergency Eco U.S.C. §1701 et seq., The Trading witl1 the Enemy Act, 50 U.S.C. App. 1 et s Orders or regulations promulgated tl1ereunder witl1 tl1e result that the investment by law or Tenant is in violation oflaw. Tenant covenants and agrees (a) to comply with all requirements of laundering, anti-terrorism, trade embargos and economic sanctions, now or he immediately notifY Landlord in writing if any of the representations, warranties this paragraph or tl1e preceding paragraph are no longer true or have been brea

Landlord, to provide such information as may be requested by Landlord compliance with the terms hereof. Tenant hereby acknowledges and agrees that Tenant's inclusion on th the Lease Tenn shall be a material default of the Lease. Notwithstanding anythi Tenant shall not permit the Premises or any portion thereof to be used or occupie on the List or by any Embargoed Person (on a permanent, temporary or transient or occupancy of the Premises by any such person or entity shall be a material def In connection with this Lease or any proposed Assignment of this Lease provide to Landlord the names of the persons holding an ownership interest in assignee or sublessee, as applicable, for purposes of compliance with Presidentia (issued September 24, 2001), as amended. 35. SEVERABILITY. If any term or provision of this Lease or the application thereof to any shall, to any extent, be invalid or unenforceable, the remainder of this Lease, o term or provision to persons or circumstances other than those as to whic unenforceable, shall not be affected thereby, and each term and provision of this enforced to the fullest extent permitted by law notwithstanding the invalidit provision hereof. 36. RIGHT OF FIRST OFFER. Provided (i) no Tenant default has occmTed and is then continuing hereu not assigned this Lease nor sublet all or any p01tion of the Premises, following t Tenant shall have a continuing right of first offer (the "Right of First Offer") to the second floor of the Building (the "Expansion Space") at such time as said E available for lease during the initial Lease Term (or following it becoming availa if such space is currently vacant); provided, however, Tenant shall have no righ the Expansion Space which is re-leased to existing tenants occupying such space Offer is subordinate to any party that has previously been granted a right of fi refusal for the same space or portion thereof, and the Right of First Offer s Expansion Space being offered and not any smaller portion. At such time as the becomes available for lease and prior to marketing the Expansion Space for lea Landlord shall notify Tenant in WTiting of Landlord's intention to market the E rental rate and terms and conditions of lease which Landlord intends to propose (collectively, the "Offer Terms"). Tenant shall have ten (10) days after its receipt of such written notice fr of Intent Negotiation Period") to provide written notice to Landlord evidencing Right of First Offer and to lease the Expansion Space in accordance with such shall not, during the Letter of Intent Negotiation Period, lease, offer to leas Expansion Space to any other party unless Tenant advises Landlord that Tenant is the Expansion Space in accordance with the Offer Tenns. In the event that Tena Offer Terms during the Letter of Intent Negotiation Period, then, after such perio

In the event Tenant agrees to the Offer Terms within the Letter of Inte hereinabove described, then Tenant and Landlord will negotiate in good faith a agreement for the lease of the Expansion Space.Landlord shall not, during period immediately following Tenant's agreement to the Offer Terms (the "Lea lease, offer to lease or agree to lease the Expansion Space to any other party. I and Tenant are unable in good faith to agree to the terms of such lease withi Period, then thereafter Landlord may market the Expansion Space upon such ter reasonably acceptable to Landlord whereupon Tenant shall have no finther ri Expansion Space until such time as the Expansion Space again becomes availa Tenant shall again have the option to exercise this Right of First Offer.

IN WITNESS WHEREOF, the parties have caused this Lease to be d pursuant to authority duly given as of the day and year f11·st above written. "LANDLORD" PALLADIAN CENTER LLC, a Delaware limi By:---- =--------------Name: James L. Dean II Title: Vice President ''TENANT" PAIDION RESEARCH, INC., a North Carolin

IN WITNESS WHEREOF, the parties have caused this Lease to be pursuant to authority duly given as of the day and year first above written. "LANDLORD" PALLADIAN CENTER LLC, a Delaware lim By' Name: James L. DeahI Title: Vice President "TENANT" PAIDION RESEARCH, INC., a North Caroli By: Name: Title: --------------------------

EXffiBIT "A" FLOOR PLAN Suite 250 Palladian II 240 Leigh Farm Road, Durham, North Carolina

EXIITBIT "A-1" FLOOR PLAN 0 liD SU Suite 245 Palladian IT 240 Leigh Fann Road, Durham, North Carolina

EXHIBIT "B" RULES AND REGULATIONS The following rules and regulations have been adopted by the Landlord and benefit of the Building and for the general comfort and welfare of the tenants I. The sidewalks, entrances, halls, passages, elevators and stauway by the Tenant or used by him for any other purpose than for ingress and egress. 2. Toilet rooms and other water apparatus shall not be used for any for which they are constructed. 3. The Tenant shall not do anything in the Premises, or bring o which shall in any way conflict with any law, ordinance, rule or regulation affe use of the Premises, which are or may hereafter be enacted or promulgated by a the Board of Fire Underwriters. 4. In order to insure proper use and care of the Premises, neither t employee of the Tenant shall: (a) Allow any furniture, packages or articles of any kind to remai shoJi periods incidental to moving same in or out of Building or to cleaning or r leased space. (b) Maintain or utilize bicycles or other vehicles in the Building. {c) Mark or defile elevators, toilet rooms, walls, windows, doors or a (d) Keep animals or birds on the Premises. (e) Deposit waste paper, diti or other substances in conidors, stair restrooms, or any other pmi of the Building not leased to Tenant. (f) Fasten any atticle, drill holes, drive nails or screws into walls, fl or othetwise mar or deface any of them by paint, papers or otherwise, unless obtained from the Landlord. (g) Operate any machinery within the Building except customary o dictaphones, calculators, electric typewritet·s, and the like.Special equipment o trade or profession of the Tenant may be operated only with the prior written cons (h) Tamper or interfere in any way with windows, doors, locks, ai heating, lighting, electric or plumbing fixtures. (i) Leave Premises unoccupied without locking all doors, extingui off all water outlets.

5. The Landlord shall have the right to prohibit any adveriising by opinion, tends to damage the reputation of the Building or its desirability, and Landlord, the Tenant shall discontinue any such adve1iising. 6. The Landlord reserves the right to designate the time when and furniture, safes, goods, merchandise and other articles may be brought into, m Building and the Premises leased by the Tenant; and wor!Gnen employed, desig Landlord must be employed by Tenant for repairs, painting, material moving an may be done on the Premises. 7. The Tenant will reimburse the Landlord for the cost of repai Premises or other pmis of the Building caused by the Tenant or the agents or e including replacing any glass broken. 8. The Landlord shall furnish a reasonable number of door keys for which shall be suJTendered on expiration of the Lease, and reserves the right to r their return at expiration of Lease. The Tenant shall obtain keys only fi·om the L duplicate keys from any outside source, and shall not alter the locks or effect any 9. · of excessive Landlord. The Tenant shall not install in the Premises any metal safes or weight in any pmiion thereof without first having obtained th 10. The Landlord reserves the right at all times to exclude news solicitors and peddlers, from the Building m1d to require registration, satisfa credentials from all persons seeking access to any pmi of the Building outside o Operation. The Landlord will exercise its best judgment in the execntion of such held liable for the granting or refusal of such access. The Landlord reserves general public from the Building after ordinary business hours and on weekends a 11. The attaching of wires to the outside of the Building is absol wires shall be run or installed in m1y pmt of the Building without the Lm1dlord's p 12. Requests for services of janitors or other Building employee Landlord. Agents or employees of Landlord shall not perform any work or do regular duties unless under special instructions fi·om Landlord. 13. Signs or any other tenant identification shall be in accordance sig11age. No signs of any nature shall be placed in the windows so as to be visibl Building. All sigus not approved in writing by the Landlord shall be subject to re 14. Any improvements or alterations to the Premises by Tenant shall by the Landlord and all such work, if approved, shall be done at the Tenant's supervision of the Landlord. 15. Tenant shall have a non-exclusive right to use all driveways and for Tenant and Tenant's employees, if deemed necessmy by Landlord. Landlord not the obligation) to tow, at the owner's expense, any vehicles parked overnigh

Business Park, or (iii) is otherwise inconsistent with the image and reputation o first class development. 16. If additional drapes or window decorations are desired by Tenan by Landlord and installed at the Tenant's expense under the direction of the Lan visible from the exterior shall be of a color approved by Landlord. 17. Premises. TI1e possession of weapons, including concealed handguns, is 18. No smoking shall be pennitted within any portion of the Building 19. The Landlord shall have the right to make such other and furt regulations as, in the judgment of the Landlord, may fi'om time to time be neces and cleanliness of the Premises, the Building or adjacent areas, and for the pre therein effective five (5) days after all tenants have been given written notice ther

EXHIBIT "C" WORKLETTER This Workletter (the "Workletter") sets fmth the rights and obligations with respect to space planning and preparing fmal construction drawings, a installation of any improvements to the Premises to be completed before th ("Tenant Improvements"). Landlord and Tenant mutually agree to the following: L Allowance. In consideration of Tenant's initial construction of the Premis and upon completion of the Tenant Improvements in accordance with Ten Landlord, Landlord agrees to contribute, towards the costs of the Tenant Imp to Ten and 00/100 Dollars ($10.00) per square foot of Suite 250 and Sui "Allowance"). Up to Seven and 00/100 Dollars ($7.00) per square foot of utilized to cover costs associated with Tenant's personal prope11y, furn fixtures, moving expenses, signage and for payment of Minimum Rent for p where Minimum Rent is otherwise abated under the Lease, upon Wl·itten req work costing in excess of the Allowance, Tenant shall pay a construction percent (3%) of the total cost of planning and construction if such constr Hundred Thousand and No/100 Dollars ($100,000.00); and five percent ( planning and construction if such construction costs are One Hundred Thous ($1 00,000.00) or less. 2. Plans. a. Tenant, at Tenant's expense, which expense may Allowance, shall provide and designate designers and engineers (c reasonably acceptable to Landlord, which Designer will complete cons drawings and specifications as required to construct the Premises, a comply with the following: i. Tenant shall provide one complete space plan order to obtain Landlord's approval of snch space plan (the "Spa Complete constmction drawings for Tenant's p jj, ceiling grid, telephone and electrical outlets, keying, and finish Drawings") based on the Space Plan. iii. Complete building standard mechanical plans installation of air conditioning system and duct work, and heating for the work to be done in the Premises ("Mechanical Draw Construction Drawings and Mechanical Drawings are collect "Plans»). b. The Plans shall be subject to Landlord's prior written ap modifications Tenant desires to make to the Plans shall also be subj

3. Work and Materials at Tenant's Expense. c. Tenant shall select Contractors licensed in State in located, to provide the work and materials to construct the Tenant Imp Landlord shall first approve such Contractors, such approval not to b conditioned or delayed. If required to ensure compliance with any appli shall have the right to reasonably designate a particular trade contract Tenant Improvements which could affect such warranty. d. All Tenant Improvements shall be constructed by Tena approved Plans and all applicable building codes and all other ap regulations. Tenant shall obtain a certificate of occupancy, if applicabl completion of the Tenant Improvements. e. Upon completion of the Tenant Improvements and prior Allowance or ush1g it as a rent credit, Tenant shall deliver to Landlord: in reasonable detail the work that has been performed; (ii) final r contractors, subcontractors and materialmen performing any work or pr the Tenant Improvements, and from any persons who have filed any n connection with the Tenant Improvements, in form and content reasona or its lender; and (iii) any suppmting doc11111entation evidencing fmal co for the Tenant Improvements reasonably requested by Landlord or its anything else contained in the Lease, only fifty percent (50%) of the All for Tenant's use prim·to December 31, 2014. Beginning January l, 201 other fifty percent (50%) of the Allowance along with any unused p percent (50%), provided, however, in no event shall the Allowance b December 31, 2015 and any unused pmtion on such date shall be deemed After completion of the items above Landlord shall pay to Tenant Contractors or Designer from the Tenant Improvement Allowance.

EXHIBIT "D" OPTION TO EXTEND Notice and Exercise. Provided no Tenant default has occurred and i I. this Lease and Tenant has not assigned this Lease nor sublet all or any portion o hereby granted the option to extend the Term twice for additional periods of t "Extension Term(s)") commencing upon the expiration of the initial Tenn or applicable, on the same terms and conditions as contained in the other provision any upfitting allowance (Tenant accepting the Premises in its "as, is" condit options and as otherwise provided in this Exhibit. The options shall be exerci written notice (the "Renewal Notice") to Landlord prior to that date which is nin scheduled Expiration Date referred to in Section l (f) of this Lease (the "Option T Minimum Rental for the Premises shall be 100% of the then fair market rental (" to the Premises. Except as otherwise set fmth herein, Tenant's occupancy of Extension Term(s) shall be subject to all other terms and conditions of this Le without limitation, the obligation to pay the Tenant Contribution. 2. Determination of Market Rate. For purposes of this Exhibit "D", the te mean the annual amount per rentable square foot that comparable landlords of the Raleigh/Durham market have accepted in then-cun-ent transactions betwe from new, non-expansion, non-renewal (unless the lease involved a procedure i tenant for a 100% determination of "fair market rental") and non-equity tenan wmthiness, for comparable space, for a compar·able use, for a comparable perio Transactions"). In any detennination of Comparable Transactions appropriat given to the annual rental rates per rentable square foot, the standard of mea rentable square footage is measured, the ratio of rentable square feet to usable escalation clause implemented, the extent of tenant's liability w1der the lease, length of the lease term, size and location of premises being leased, at1d ot conditions of tenancy for such Comparable Transactions. The intent is that Ten rent and other economic benefits that Landlord would otheJwise give in Comp that Landlord will make, and receive the same economic payments that Landlord and receive in Comparable Transactions. Landlord shall detennine the Mar·ket Rate by using its good faith judg Tenant, Landlord shall provide Tenant written notice of such amount thirty (30) Te1mination Date. In the event Tenant exercises its option to extend the Term pursuant to th and Tenant shall execute an amendment to the Lease stating the new expiration d new Minimum Rent in effect.

THIS FIRST AMENDMENT TO LEASE (this "First Amendment") is entered into ember 18, 2015 (the "Effective Date") by and between PALLADIAN CENTER LLC, a D ed liability company ("Landlord") and PAIDION RESEARCH, INC., a North Carolina corp nant"). WIT N E S S E T H: A. Landlord and Tenant entered into a Lease dated as of April 10, 2014 (the " e"), whereby Landlord leased to Tenant and Tenant leased from Landlord approximately ble square feet ("Suite 250") located on the second (2nd) floor of the Building (as defined e) at 240 Leigh Farm Road, Durham, NC and 6,941 rentable square feet ("Suite 245") located nd (2nd) floor of the Building which will be added to Suite 250 on April 1, 2017 (the iguration of the leased space being defined as the "Premises"); and B. Tenant and Landlord desire to amend the Original Lease (i) to allow Tenant to ap ed portion of the Allowance, as defined in the Lease, toward the payment of Minimum Rental ce the size of the right of first offer space, and (iii) to modify other terms and conditions inal Lease, all in accordance with the terms and conditions provided herein; and C. All capitalized terms not otherwise defined herein shall have the respective mean in the Original Lease. For purposes hereof, the Original Lease as amended by this First Ame ferred to as the "Lease." NOW, THEREFORE, in consideration of the agreements herein contained and other go able consideration, the receipt and sufficiency of which are hereby acknowledged, the parties e as follows: 1. Recitals. The recitals shall form a part of this First Amendment. 2. Allowance Applied Toward Minimum Rental.Currently Forty-Three Thousa dred Thirty-Four and 00/100 Dollars ($43,134.00) remains of the Allowance under the Lea maining Allowance"). Landlord has agreed that so long as Tenant is not in default under th nd applicable notice and cure periods, Tenant may apply the Remaining Allowance tow ent of Minimum Rental under the Lease for the months of October, November, and Decemb for a partial month of January 2016. For January 2016 Tenant shall owe the remaining am mum Rental due for such month on or before January 1, 2016. Tenant shall have no other r ct any portion of the Allowance. 3. Right of First Offer. The parties agree that the Expansion Space, as defined in Sec e Lease, is hereby revised so that "Expansion Space" shall mean only Suite 200 of the B h contains approximately 1,961 rentable square feet as shown on Exhibit A-1 attached her not apply to any other space in the Building. 4. Broker. Landlord and Tenant represent and warrant each to the other that they h with any broker(s) except CB Richard Ellis-Raleigh, LLC, which represents the Landlord a erties, Inc., which represents the Tenant (collectively, the "Broker") and neither Broker is cl entitlement to a commission in connection with this transaction. Tenant agrees to indemnify a

action. 5. Execution of Counterparts. This First Amendment may be executed in m terparts, each counterpart being executed by less than all of the parties hereto, and shall be tive as if a single original had been signed by all parties; but all such counterparts shall be dee titute a single agreement, and this First Amendment shall not be or become effective unless an of the signatory parties below has signed at least one such counterpart and caused the counte uted to be delivered to both of the other parties. 9. Authority. Each individual signing this First Amendment on behalf of any party sents that he or she has full right, power and authority to enter into this First Amendment and party for which he or she purports to sign this First Amendment. 10. Binding Agreement. This First Amendment is binding upon and shall inure to the l parties hereto, and to their respective heirs, executors, administrators, predecessors, succ ns, parents and subsidiary corporations, divisions, officers, directors, partners, agents, attorne oyees, as applicable. 11. Ratification. Except as expressly or by necessary implication amended or m by, the terms of the Lease are hereby ratified, confirmed and continued in full force and nt acknowledges that, to its knowledge (i) Landlord is not in default under the Lease, and (i s no breach, default, or event or condition which, with the giving of notice or the passage of would constitute a breach or default by Landlord under the Lease. To Tenant's knowledge, as hereof, there is no defense, offset, claim or counterclaim by or in favor of Tenant against La r the Lease. Tenant acknowledges all work to be performed by Landlord under the Lease h pleted in accordance with the Lease and has been accepted by Tenant and all reimburseme ances due to Tenant under the Lease have been paid in full. [Remainder of Page Left Blank Intentionally]

LANDLORD: PALLADIAN CENTER LLC, a Delaware limited liabili company By: Name: James L. DemliJ Title: Vice President TENANT: PAIDION RESEARCH, INC., a North Carolina corpora l By: Name: Betsy Reid\ Its: Chief Operating Officer 9/A/;5 Date:

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EXHIBIT B

[Subleased Premises]

EXHIBIT C

[Demising Wall]