0001104659-21-066745.txt : 20210514 0001104659-21-066745.hdr.sgml : 20210514 20210514143710 ACCESSION NUMBER: 0001104659-21-066745 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20210331 FILED AS OF DATE: 20210514 DATE AS OF CHANGE: 20210514 EFFECTIVENESS DATE: 20210514 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Sofinnova Investments, Inc. CENTRAL INDEX KEY: 0001631134 IRS NUMBER: 000000000 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-18774 FILM NUMBER: 21923825 BUSINESS ADDRESS: STREET 1: 3000 Sand Hill Road STREET 2: BUILDING 4-SUITE 250 CITY: Menlo Park STATE: CA ZIP: 94025 BUSINESS PHONE: 650.681.8428 MAIL ADDRESS: STREET 1: 3000 Sand Hill Road STREET 2: BUILDING 4-SUITE 250 CITY: Menlo Park STATE: CA ZIP: 94025 FORMER COMPANY: FORMER CONFORMED NAME: Sofinnova Ventures Inc DATE OF NAME CHANGE: 20150120 13F-HR 1 primary_doc.xml 13F-HR LIVE false false false 0001631134 XXXXXXXX 03-31-2021 03-31-2021 false Sofinnova Investments, Inc.

3000 Sand Hill Road Building 4-Suite 250 Menlo Park CA 94025

13F HOLDINGS REPORT 028-18774 Y Sofinnova Investments, Inc. is filing this Form 13F on behalf of itself and the general partner entities of the investment funds for which it serves as the investment adviser, Sofinnova Management VII, L.L.C., Sofinnova Management VIII, L.L.C., Sofinnova Management IX, L.L.C., Sofinnova Management X, L.L.C., and Sofinnova BioEquities GP LLC. Nathalie Auber 650-681-8428 /s/ Nathalie Auber Menlo Park CA 05-14-2021 0 64 1663412 INFORMATION TABLE 2 infotable.xml Akouos, Inc COMM 00973J101 21014 1515074 SH SOLE 1515074 0 0 Amarin Corp ADR 023111206 7269 1170584 SH SOLE 1170584 0 0 Ascendis Pharma A/S ADR 04351P101 67265 521923 SH SOLE 521923 0 0 Athira Pharma, Inc. COMM 04746L104 9369 509168 SH SOLE 509168 0 0 Bolt Biotherapeutics, Inc. COMM 097702104 90649 2754437 SH SOLE 2754437 0 0 Checkmate Pharmaceuticals Inc COMM 162818108 43785 3606707 SH SOLE 3606707 0 0 Coherus BioSciences COMM 19249H103 6349 434555 SH SOLE 434555 0 0 Galera Therapeutics, Inc COMM 36338D108 27198 3083712 SH SOLE 3083712 0 0 Inozyme Pharma, Inc. COMM 45790W108 40160 2028308 SH SOLE 2028308 0 0 Karuna Therapeutics, Inc. COMM 48576A100 234742 1952441 SH SOLE 1952441 0 0 Merus N.V. COMM N5749R100 27388 1311039 SH SOLE 1311039 0 0 Natera COMM 632307104 314831 3100560 SH SOLE 3100560 0 0 Nextcure, Inc COMM 65343E108 26745 2671856 SH SOLE 2671856 0 0 Nucana Biomed Ltd ADR 67022C106 27944 5599999 SH SOLE 5599999 0 0 Nucana Biomed Ltd Ordinary Shares GB00BYWYV 11976 2400000 SH SOLE 2400000 0 0 ObsEva SA COMM H5861P103 15436 4749623 SH SOLE 4749623 0 0 PDS Biotechnology Corporation COMM 70465T107 649 142635 SH SOLE 142635 0 0 Synlogic Inc. COMM 87166L100 2058 574972 SH SOLE 574972 0 0 Y-mAbs Therapeutics, Inc COMM 984241109 66355 2194278 SH SOLE 2194278 0 0 Acceleron Pharma Inc COMM 00434H108 24212 178538 SH SOLE 178538 0 0 Agenus Inc COMM 00847G705 9461 3478201 SH SOLE 3478201 0 0 Align Technology Inc COMM 016255101 24640 45500 SH SOLE 45500 0 0 Aligos Therapeutics Inc COMM 01626L105 4219 185532 SH SOLE 185532 0 0 Amgen Inc COMM 031162100 9671 38868 SH SOLE 38868 0 0 Aptose Biosciences Inc COMM 03835T200 4164 696928 SH SOLE 696928 0 0 Arena Pharmaceuticals Inc COMM 040047607 6346 91448 SH SOLE 91448 0 0 AstraZeneca PLC ADR 046353108 51497 1035732 SH SOLE 1035732 0 0 BioCryst Pharmaceuticals Inc COMM 09058V103 3852 378774 SH SOLE 378774 0 0 Calithera Biosciences Inc COMM 13089P101 1833 757533 SH SOLE 757533 0 0 ChemoCentryx Inc COMM 16383L956 7686 150000 SH Put SOLE 150000 0 0 ChemoCentryx Inc COMM 16383L106 9223 179999 SH SOLE 179999 0 0 Cytokinetics Inc COMM 23282W605 9065 389720 SH SOLE 389720 0 0 Dexcom Inc COMM 252131107 9704 27000 SH SOLE 27000 0 0 Eli Lilly and Co COMM 532457108 33721 180501 SH SOLE 180501 0 0 Exelixis Inc COMM 30161Q104 18957 839181 SH SOLE 839181 0 0 Fate Therapeutics Inc COMM 31189P102 4518 54795 SH SOLE 54795 0 0 Gilead Sciences Inc COMM 375558903 19389 300000 SH Call SOLE 300000 0 0 Health Care Select Sector SPDR COMM 81369Y959 46696 400000 SH Put SOLE 400000 0 0 Heron Therapeutics Inc COMM 427746902 4053 250000 SH Call SOLE 250000 0 0 Horizon Therapeutics PLC COMM G46188101 12333 133997 SH SOLE 133997 0 0 Immatics NV COMM N44445109 4317 385099 SH SOLE 385099 0 0 Insmed Inc COMM 457669307 21081 618950 SH SOLE 618950 0 0 Insulet Corp COMM 45784P101 4566 17500 SH SOLE 17500 0 0 Intra-Cellular Therapies Inc COMM 46116X101 22224 655001 SH SOLE 655001 0 0 Jazz Pharmaceuticals PLC COMM G50871105 42067 255928 SH SOLE 255928 0 0 Jounce Therapeutics Inc COMM 481116101 5256 511822 SH SOLE 511822 0 0 Kura Oncology Inc COMM 50127T109 2351 83164 SH SOLE 83164 0 0 MacroGenics Inc COMM 556099109 2331 73201 SH SOLE 73201 0 0 Marinus Pharmaceuticals Inc COMM 56854Q200 5733 370351 SH SOLE 370351 0 0 Mirati Therapeutics Inc COMM 60468T105 23645 138030 SH SOLE 138030 0 0 Mirum Pharmaceuticals Inc COMM 604749101 9442 476401 SH SOLE 476401 0 0 Otonomy Inc COMM 68906L105 3191 1251256 SH SOLE 1251256 0 0 PTC Therapeutics Inc COMM 69366J200 22105 466840 SH SOLE 466840 0 0 Protagonist Therapeutics Inc COMM 74366E102 16962 654900 SH SOLE 654900 0 0 Puma Biotechnology Inc COMM 74587V107 3353 344917 SH SOLE 344917 0 0 Reata Pharmaceuticals Inc COMM 75615P103 23780 238520 SH SOLE 238520 0 0 Regenxbio Inc COMM 75901B107 12339 361735 SH SOLE 361735 0 0 Replimune Group Inc COMM 76029N106 4339 142209 SH SOLE 142209 0 0 Savara Inc COMM 805111101 3614 1737450 SH SOLE 1737450 0 0 Syndax Pharmaceuticals Inc COMM 87164F105 6678 298644 SH SOLE 298644 0 0 TCR2 Therapeutics Inc COMM 87808K106 7434 336682 SH SOLE 336682 0 0 Uniqure NV COMM N90064101 14390 427122 SH SOLE 427122 0 0 United Therapeutics Corp COMM 91307C102 35972 215054 SH SOLE 215054 0 0 Vertex Pharmaceuticals Inc COMM 92532F100 9820 45700 SH SOLE 45700 0 0