0001104659-21-023887.txt : 20210216 0001104659-21-023887.hdr.sgml : 20210216 20210216160451 ACCESSION NUMBER: 0001104659-21-023887 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20201231 FILED AS OF DATE: 20210216 DATE AS OF CHANGE: 20210216 EFFECTIVENESS DATE: 20210216 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Sofinnova Investments, Inc. CENTRAL INDEX KEY: 0001631134 IRS NUMBER: 000000000 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-18774 FILM NUMBER: 21638005 BUSINESS ADDRESS: STREET 1: 3000 Sand Hill Road STREET 2: BUILDING 4-SUITE 250 CITY: Menlo Park STATE: CA ZIP: 94025 BUSINESS PHONE: 650.681.8428 MAIL ADDRESS: STREET 1: 3000 Sand Hill Road STREET 2: BUILDING 4-SUITE 250 CITY: Menlo Park STATE: CA ZIP: 94025 FORMER COMPANY: FORMER CONFORMED NAME: Sofinnova Ventures Inc DATE OF NAME CHANGE: 20150120 13F-HR 1 primary_doc.xml 13F-HR LIVE false false false 0001631134 XXXXXXXX 12-31-2020 12-31-2020 false Sofinnova Investments, Inc.

3000 Sand Hill Road Building 4-Suite 250 Menlo Park CA 94025

13F HOLDINGS REPORT 028-18774 Y Sofinnova Investments, Inc. is filing this Form 13F on behalf of itself and the general partner entities of the investment funds for which it serves as the investment adviser, Sofinnova Management VII, L.L.C., Sofinnova Management VIII, L.L.C., Sofinnova Management IX, L.L.C., Sofinnova Management X, L.L.C., and Sofinnova BioEquities GP LLC. Nathalie Auber 650-681-8428 /s/ Nathalie Auber Menlo Park CA 02-16-2020 0 69 1679836 INFORMATION TABLE 2 infotable.xml Aclaris Therapeutics COMM 00461U105 12368 1911573 SH SOLE 1911573 0 0 Akouos, Inc ADR 00973J101 30044 1515074 SH SOLE 1515074 0 0 Amarin Corp ADR 023111206 5724 1170584 SH SOLE 1170584 0 0 Ascendis Pharma A/S ADR 04351P101 185105 1109874 SH SOLE 1109874 0 0 Athira Pharma, Inc. COMM 04746L104 17439 509168 SH SOLE 509168 0 0 Checkmate Pharmaceuticals Inc COMM 162818108 52622 3606707 SH SOLE 3606707 0 0 Coherus BioSciences COMM 19249H103 7553 434555 SH SOLE 434555 0 0 Galera Therapeutics, Inc COMM 36338D108 31546 3083712 SH SOLE 3083712 0 0 Inozyme Pharma, Inc. COMM 45790W108 41864 2028308 SH SOLE 2028308 0 0 Karuna Therapeutics, Inc. COMM 48576A100 198348 1952441 SH SOLE 1952441 0 0 Merus N.V. COMM N5749R100 22983 1311039 SH SOLE 1311039 0 0 Natera COMM 632307104 308568 3100560 SH SOLE 3100560 0 0 Nextcure, Inc COMM 00653E112 29123 2671856 SH SOLE 2671856 0 0 Nucana Biomed Ltd ADR 67022C106 25144 5599999 SH SOLE 5599999 0 0 Nucana Biomed Ltd Ordinary Shares GBOOBYWYV 10776 2400000 SH SOLE 2400000 0 0 ObsEva SA COMM H5861P103 9879 4749623 SH SOLE 4749623 0 0 PDS Biotechnology Corporation COMM 70465T107 305 142635 SH SOLE 142635 0 0 Synlogic Inc. COMM 87166L100 1242 574972 SH SOLE 574972 0 0 Y-mAbs Therapeutics, Inc COMM 984241109 108639 2194278 SH SOLE 2194278 0 0 ACADIA Pharmaceuticals Inc COMM 004225108 8801 164625 SH SOLE 164625 0 0 Abbvie Inc COMM 00287Y109 31459 293596 SH SOLE 293596 0 0 Acceleron Pharma Inc COMM 00434H108 4694 36688 SH SOLE 36688 0 0 Aligos Therapeutics Inc COMM 01626L105 5283 191061 SH SOLE 191061 0 0 Amgen Inc COMM 031162100 37859 164663 SH SOLE 164663 0 0 Aptose Biosciences Inc COMM 03835T200 4297 981135 SH SOLE 981135 0 0 Arcus Biosciences Inc COMM 03969F109 4836 186278 SH SOLE 186278 0 0 Arena Pharmaceuticals Inc COMM 040047607 9325 121373 SH SOLE 121373 0 0 AstraZeneca PLC ADR 046353108 42122 842600 SH SOLE 842600 0 0 BioCryst Pharmaceuticals Inc COMM 09058V103 8365 1122800 SH SOLE 1122800 0 0 Bioatla Inc COMM 09077B104 102 3000 SH SOLE 3000 0 0 Biomarin Pharmaceutical Inc COMM 09061G101 14429 164545 SH SOLE 164545 0 0 Calithera Biosciences Inc COMM 13089P101 2457 500326 SH SOLE 500326 0 0 Calithera Biosciences Inc COMM 13089P101 123 25000 SH Call SOLE 25000 0 0 Calithera Biosciences Inc COMM 13089P101 737 150000 SH Call SOLE 150000 0 0 Calithera Biosciences Inc COMM 13089P101 1964 400000 SH Put SOLE 400000 0 0 ChemoCentryx Inc COMM 16383L106 7010 113213 SH SOLE 113213 0 0 Cytokinetics Inc COMM 23282W605 10564 508394 SH SOLE 508394 0 0 Eli Lilly and Co COMM 532457108 6232 36909 SH SOLE 36909 0 0 Fate Therapeutics Inc COMM 31189P102 1227 13497 SH SOLE 13497 0 0 GW Pharmaceuticals PLC ADR 36197T103 11629 100762 SH SOLE 100762 0 0 Health Care Select Sector SPDR COMM 81369Y209 34032 300000 SH Put SOLE 300000 0 0 Horizon Therapeutics PLC COMM G46188101 15609 213390 SH SOLE 213390 0 0 IGM Biosciences Inc COMM 449585108 3985 45131 SH SOLE 45131 0 0 Immatics NV COMM N44445109 3016 279532 SH SOLE 279532 0 0 Insmed Inc COMM 457669307 10309 309662 SH SOLE 309662 0 0 Intra-Cellular Therapies Inc COMM 46116X101 26972 848162 SH SOLE 848162 0 0 Iovance Biotherapeutics Inc COMM 462260100 4640 100000 SH Put SOLE 100000 0 0 Jazz Pharmaceuticals PLC COMM G50871105 35141 212911 SH SOLE 212911 0 0 Jounce Therapeutics Inc COMM 481116101 6477 925280 SH SOLE 925280 0 0 Kadmon Holdings Inc COMM 48283N106 950 228893 SH SOLE 228893 0 0 Kura Oncology Inc COMM 50127T109 3941 120677 SH SOLE 120677 0 0 Liquidia Corp COMM 53635D202 436 147744 SH SOLE 147744 0 0 MacroGenics Inc COMM 556099109 10488 458807 SH SOLE 458807 0 0 Marinus Pharmaceuticals Inc COMM 56854Q200 3343 274027 SH SOLE 274027 0 0 Mirum Pharmaceuticals Inc COMM 604749101 7944 454974 SH SOLE 454974 0 0 Otonomy Inc COMM 68906L105 16956 2620668 SH SOLE 2620668 0 0 PTC Therapeutics Inc COMM 69366J200 19315 316478 SH SOLE 316478 0 0 Protagonist Therapeutics Inc COMM 00744E106 14614 724904 SH SOLE 724904 0 0 Puma Biotechnology Inc COMM 74587V107 6460 629650 SH SOLE 629650 0 0 Reata Pharmaceuticals Inc COMM 75615P103 18412 148937 SH SOLE 148937 0 0 Regenxbio Inc COMM 75901B107 12298 271114 SH SOLE 271114 0 0 Replimune Group Inc COMM 76029N106 763 20000 SH SOLE 20000 0 0 Sarepta Therapeutics Inc COMM 803607100 8840 51848 SH SOLE 51848 0 0 Syndax Pharmaceuticals Inc COMM 87164F105 8293 372909 SH SOLE 372909 0 0 TCR2 Therapeutics Inc COMM 87808K106 10322 333707 SH SOLE 333707 0 0 TG Therapeutics Inc COMM 88322Q108 3406 65474 SH SOLE 65474 0 0 United Therapeutics Corp COMM 91307C102 52808 347901 SH SOLE 347901 0 0 Zogenix Inc COMM 98978L204 1791 89579 SH SOLE 89579 0 0 iShares Russell 2000 ETF COMM 464287655 25488 130000 SH Put SOLE 130000 0 0