0001012975-19-000197.txt : 20190226 0001012975-19-000197.hdr.sgml : 20190226 20190226210334 ACCESSION NUMBER: 0001012975-19-000197 CONFORMED SUBMISSION TYPE: 4 PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20190222 FILED AS OF DATE: 20190226 DATE AS OF CHANGE: 20190226 REPORTING-OWNER: OWNER DATA: COMPANY CONFORMED NAME: Burow Kristina CENTRAL INDEX KEY: 0001569248 FILING VALUES: FORM TYPE: 4 SEC ACT: 1934 Act SEC FILE NUMBER: 001-38155 FILM NUMBER: 19635536 MAIL ADDRESS: STREET 1: 8755 W. HIGGINS ROAD STREET 2: SUITE 1025 CITY: CHICAGO STATE: IL ZIP: 60631 ISSUER: COMPANY DATA: COMPANY CONFORMED NAME: Sienna Biopharmaceuticals, Inc. CENTRAL INDEX KEY: 0001656328 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 273364627 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 BUSINESS ADDRESS: STREET 1: 30699 RUSSELL RANCH ROAD, SUITE 140 CITY: WESTLAKE VILLAGE STATE: CA ZIP: 91362 BUSINESS PHONE: (818) 629-2256 MAIL ADDRESS: STREET 1: 30699 RUSSELL RANCH ROAD, SUITE 140 CITY: WESTLAKE VILLAGE STATE: CA ZIP: 91362 FORMER COMPANY: FORMER CONFORMED NAME: Sienna Labs, Inc. DATE OF NAME CHANGE: 20151020 4 1 edgar.xml PRIMARY DOCUMENT X0306 4 2019-02-22 0001656328 Sienna Biopharmaceuticals, Inc. SNNA 0001569248 Burow Kristina 8755 WEST HIGGINS ROAD SUITE 1025 CHICAGO IL 60631 1 0 0 0 Common Stock 2019-02-22 4 P 0 150000 2.50 A 2900575 I See footnote Common Stock 2019-02-22 4 P 0 150000 2.50 A 1032493 I See footnote Common Stock 2019-02-22 4 P 0 1865800 2.50 A 1865800 I See footnote The shares are directly held of record by ARCH Venture Fund VIII, L.P. ("ARCH Fund VIII"). The sole general partner of ARCH Fund VIII is ARCH Venture Partners VIII, L.P. ("ARCH Partners VIII"). The sole general partner of ARCH Partners VIII is ARCH Venture Partners VIII, LLC ("ARCH VIII LLC"). ARCH Partners VIII and ARCH VIII LLC may therefore be deemed to beneficially own the securities held by ARCH Fund VIII. The Reporting Person has an interest in ARCH Partners VIII and ARCH VIII LLC, but does not have voting or investment control over the shares held by ARCH Fund VIII. The Reporting Person disclaims beneficial ownership of such shares except to the extent of any pecuniary interest therein. The shares are directly held of record by ARCH Venture Fund VIII Overage, L.P. ("ARCH Fund Overage"). The sole general partner of ARCH Fund Overage is ARCH VIII LLC. ARCH VIII LLC may therefore be deemed to beneficially own the securities held by ARCH Fund Overage. The Reporting Person has an interest in ARCH VIII LLC, but does not have voting or investment control over the shares held by ARCH Fund Overage. The Reporting Person disclaims beneficial ownership of such shares except to the extent of any pecuniary interest therein. The shares are directly held of record by ARCH Venture Fund X Overage, L.P. ("ARCH X Overage"). The sole general Partner of ARCH X Overage is ARCH Venture Partners X Overage, L.P. ("AVP X Over GP"). The sole general partner of AVP X Over GP is ARCH Venture Partners X, LLC ("AVP X LLC"). AVP X Over LP and AVP X LLC may therefore be deemed to beneficially own the securities held by ARCH X Overage. AVP X Over GP and AVP X LLC disclaim beneficial ownership of such securities, except to the extent of any pecuniary interest therein. The Reporting Person is a managing director of AVP X LLC and may be deemed to beneficially own the shares held by ARCH X Overage. The Reporting Person disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein. /s/ Mark McDonnell, Attorney-in-Fact for Kristina Burow 2019-02-26 EX-24 2 attach_1.htm

POWERS OF ATTORNEY



KNOW ALL MEN BY THESE PRESENTS, that each person whose signature appears

below hereby constitutes and appoints Mark McDonnell his or its true and

lawful attorney-in-fact, with full power of substitution, to sign any and

all instruments, certificates and documents that may be necessary, desirable

or appropriate to be executed on behalf of himself as an individual or in

his capacity as a direct or indirect general partner, member, director,

officer or manager of any partnership, corporation or limited liability

company, pursuant to section 13 or 16 of the Securities Exchange Act of 1934,

as amended (the "Exchange Act"), and any and all regulations promulgated

thereunder, and to file the same, with all exhibits thereto, and any other

documents in connection therewith, with the Securities and Exchange Commission,

and with any other entity when and if such is mandated by the Exchange Act or

by the Financial Industry Regulatory Authority, granting unto said

attorney-in-fact full power and authority to do and perform each and every

act and thing necessary, desirable or appropriate, fully to all intents and

purposes as he might or could do in person, thereby ratifying and confirming

all that said attorney-in-fact, or his substitutes, may lawfully do or cause

to be done by virtue hereof.  This Power of Attorney shall remain in full force

and effect with respect to each undersigned person unless and until six months

after such person is both no longer a Managing Director of ARCH Venture Partners

and no longer serving on the board of directors of any portfolio company of any

ARCH Venture Partners fund.



IN WITNESS WHEREOF, this Power of Attorney has been signed as of the 21th day

of February, 2019.



ARCH VENTURE FUND X, L.P.



By: ARCH Venture Partners X, L.P.

its General Partner

By: ARCH Venture Partners X, LLC

its General Partner

By: /s/ Keith Crandell

Managing Director



ARCH VENTURE PARTNERS X, L.P.



By: ARCH Venture Partners X, LLC

its General Partner

By: /s/ Keith Crandell

Managing Director



ARCH VENTURE FUND X OVERAGE, L.P.



By: ARCH Venture Partners X Overage, L.P.

its General Partner

By: ARCH Venture Partners X, LLC

its General Partner

By: /s/ Keith Crandell

Managing Director



ARCH VENTURE PARTNERS X OVERAGE, L.P.



By: ARCH Venture Partners X, LLC

its General Partner

By: /s/ Keith Crandell

Managing Director



ARCH VENTURE PARTNERS X, LLC



By: /s/Keith Crandell

Managing Director



/s/ Keith Crandell

Keith Crandell



/s/ Kristina Burow

Kristina Burow



/s/ Robert Nelsen

Robert Nelsen



/s/ Steven Gillis

Steven Gillis