0001213900-16-013630.txt : 20160519 0001213900-16-013630.hdr.sgml : 20160519 20160519205424 ACCESSION NUMBER: 0001213900-16-013630 CONFORMED SUBMISSION TYPE: 4 PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20160517 FILED AS OF DATE: 20160519 DATE AS OF CHANGE: 20160519 ISSUER: COMPANY DATA: COMPANY CONFORMED NAME: Karyopharm Therapeutics Inc. CENTRAL INDEX KEY: 0001503802 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 263931704 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 BUSINESS ADDRESS: STREET 1: 85 WELLS AVENUE STREET 2: SECOND FLOOR CITY: NEWTON STATE: MA ZIP: 02459 BUSINESS PHONE: 617-658-0600 MAIL ADDRESS: STREET 1: 85 WELLS AVENUE STREET 2: SECOND FLOOR CITY: NEWTON STATE: MA ZIP: 02459 REPORTING-OWNER: OWNER DATA: COMPANY CONFORMED NAME: Hadjimichael Andreas CENTRAL INDEX KEY: 0001591256 FILING VALUES: FORM TYPE: 4 SEC ACT: 1934 Act SEC FILE NUMBER: 001-36167 FILM NUMBER: 161664562 MAIL ADDRESS: STREET 1: SIMOU MENARDOU 8, RIA COURT 8 STREET 2: OFFICE 101, 6015 CITY: LARNACA STATE: G4 ZIP: 00000 REPORTING-OWNER: OWNER DATA: COMPANY CONFORMED NAME: Smolokowski Wiaczeslaw CENTRAL INDEX KEY: 0001591274 FILING VALUES: FORM TYPE: 4 SEC ACT: 1934 Act SEC FILE NUMBER: 001-36167 FILM NUMBER: 161664563 MAIL ADDRESS: STREET 1: SIMOU MENARDOU 8, RIA COURT 8 STREET 2: OFFICE 101, 6015 CITY: LARNACA STATE: G4 ZIP: 00000 REPORTING-OWNER: OWNER DATA: COMPANY CONFORMED NAME: Hadjimichael George CENTRAL INDEX KEY: 0001674499 FILING VALUES: FORM TYPE: 4 SEC ACT: 1934 Act SEC FILE NUMBER: 001-36167 FILM NUMBER: 161664564 MAIL ADDRESS: STREET 1: SIMOU MENARDOU 8, RIA COURT 8 STREET 2: OFFICE 101, 6015 CITY: LARNACA STATE: G4 ZIP: 00000 REPORTING-OWNER: OWNER DATA: COMPANY CONFORMED NAME: Czernik Marcin CENTRAL INDEX KEY: 0001591275 FILING VALUES: FORM TYPE: 4 SEC ACT: 1934 Act SEC FILE NUMBER: 001-36167 FILM NUMBER: 161664565 MAIL ADDRESS: STREET 1: SIMOU MENARDOU 8, RIA COURT 8 STREET 2: OFFICE 101, 6015 CITY: LARNACA STATE: G4 ZIP: 00000 REPORTING-OWNER: OWNER DATA: COMPANY CONFORMED NAME: Chione Ltd CENTRAL INDEX KEY: 0001590232 FILING VALUES: FORM TYPE: 4 SEC ACT: 1934 Act SEC FILE NUMBER: 001-36167 FILM NUMBER: 161664566 BUSINESS ADDRESS: STREET 1: SIMOU MENARDOU 8, RIA COURT 8 STREET 2: OFFICE 101, 6015 CITY: LARNACA STATE: G4 ZIP: CY BUSINESS PHONE: 48 (22) 840 8342 MAIL ADDRESS: STREET 1: SIMOU MENARDOU 8, RIA COURT 8 STREET 2: OFFICE 101, 6015 CITY: LARNACA STATE: G4 ZIP: CY 4 1 f4051716chione_karyopharm.xml OWNERSHIP DOCUMENT X0306 4 2016-05-17 0 0001503802 Karyopharm Therapeutics Inc. KPTI 0001590232 Chione Ltd SIMOU MENARDOU 8 RIA COURT 8, OFFICE 101 6015 LARNACA G4 CYPRUS 0 0 1 0 0001591275 Czernik Marcin SIMOU MENARDOU 8, RIA COURT 8, OFFICE 101 6015 LARNACA G4 CYPRUS 0 0 1 0 0001591256 Hadjimichael Andreas SIMOU MENARDOU 8, RIA COURT 8, OFFICE 101 6015 LARNACA G4 CYPRUS 0 0 1 0 0001674499 Hadjimichael George SIMOU MENARDOU 8, RIA COURT 8, OFFICE 101 6015 LARNACA G4 CYPRUS 0 0 1 0 0001591274 Smolokowski Wiaczeslaw CHALET LENOTCHKA CH.DE BARNOUD 1885 CHESIERES SWITZERLAND G4 00000 CYPRUS 0 0 1 0 COMMON STOCK 2016-05-17 4 S 0 33800 8.1503 D 8923932 D COMMON STOCK 2016-05-18 4 S 0 30000 8.1496 D 8893932 D The prices reported in Column 4 are weighted average prices. The 33,800 shares referred to in the first row of Column 4 were sold at prices ranging from $8.05 to $8.44, inclusive. The 30,000 shares referred to in the second row of Column 4 were sold at prices ranging from $8.10 to $8.26, inclusive. The reporting persons undertake to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within each of the ranges set forth in footnote 1 above. Shares of Common Stock are owned directly by Chione Limited ("Chione"). Chione's directors, Marcin Czernik, Andreas Hadjimichael and George Hadjimichael, may be deemed to share voting and investment power and beneficial ownership of the shares of Common Stock directly owned by Chione. Wiaczeslaw Smolokowski, the sole shareholder of Chione, may also be deemed to share voting and investment power and beneficial ownership of the shares of Common Stock directly owned by Chione. Each reporting person states that neither the filing of this Form 4 nor anything herein shall be deemed an admission that such person or any other person is, for purposes of Section 16 of the Securities Exchange Act of 1934, as amended (the "Act"), or otherwise, the beneficial owner of any securities covered by this Form 4. Beneficial ownership of the securities covered by this statement is disclaimed, except, with respect to any person, to the extent of the pecuniary interest of such person in such securities. Each reporting person may be deemed to be a member of a group with respect to the issuer or securities of the issuer for purposes of Section 13(d) or 13(g) of the Act. Each reporting person declares that neither the filing of this Form 4 nor anything herein shall be construed as an admission that such person or any other person is, for the purposes of Section 13(d) or 13(g) of the Act or any other purpose, a member of a group with respect to the issuer or securities of the issuer. Exhibit Index Exhibit 24.1 - Power of Attorney, dated May 12, 2016, made by Marcin Czernik and Chione Limited in favor of Simon Prisk (previously filed) Exhibit 24.2 - Power of Attorney, dated May 12, 2016, made by Andreas Hadjimichael and Chione Limited in favor of Simon Prisk (previously filed) Exhibit 24.3 - Power of Attorney, dated February 15, 2016, made by George Hadjimichael and Chione Limited in favor of Simon Prisk (previously filed) Exhibit 24.4 - Power of Attorney, dated May 12, 2016, made by Wiaczeslaw Smolokowski in favor of Simon Prisk Exhibit (previously filed) 99.1 - Joint Filer Information (filed herewith) Exhibit 99.2 - Joint Filing Agreement (previously filed). All previously filed Exhibits were filed with the Form 4 of the reporting persons, filed on May 12, 2016, except that Exhibit 24.3 was filed with the Schedule 13G/A of the reporting persons, filed on March 9, 2016. /s/ Chione Limited, by /s/ Simon Prisk, as attorney-in fact by power of attorney 2016-05-19 /s/ Marcin Czernik, by /s/ Simon Prisk, as attorney-in fact by power of attorney 2016-05-19 /s/ Andreas Hadjimichael, by /s/ Simon Prisk, as attorney-in fact by power of attorney 2016-05-19 /s/ George Hadjimichael, by /s/ Simon Prisk, as attorney-in fact by power of attorney 2016-05-19 /s/ Wiaczeslaw Smolokowski, by /s/ Simon Prisk, as attorney-in fact by power of attorney 2016-05-19 EX-99.1 2 f4051716ex99ichione_karyo.htm JOINT FILER INFORMATION

Exhibit 99.1

Joint Filer Information

(Other Reporting Persons)

Name:

Marcin Czernik

Address:

Simou Menardou 8

Ria Court 8, Office 101

6015 Larnaca, Cyprus

Designated Filer:

Chione Limited

Issuer & Ticker Symbol:

Karyopharm Therapeutics Inc. [KPTI]

Date of Earliest Transaction Required to Be Reported:

05/17/2016

Relationship of Reporting Persons to Issuer:

If Amendment, Date Original Filed (Month/Day/Year):

Individual or Joint/Group Filing:

Signature and Date:

10% Owner

Not Applicable

Form filed by More than One Reporting Person

Marcin Czernik, by /s/ Simon Prisk, as attorney-in fact by power of attorney 05/19/2016