0001493152-21-011440.txt : 20210514 0001493152-21-011440.hdr.sgml : 20210514 20210514130150 ACCESSION NUMBER: 0001493152-21-011440 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20210331 FILED AS OF DATE: 20210514 DATE AS OF CHANGE: 20210514 EFFECTIVENESS DATE: 20210514 FILER: COMPANY DATA: COMPANY CONFORMED NAME: RTW INVESTMENTS, LP CENTRAL INDEX KEY: 0001493215 IRS NUMBER: 000000000 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-16670 FILM NUMBER: 21923301 BUSINESS ADDRESS: STREET 1: 40 10TH AVENUE STREET 2: 7TH FLOOR CITY: NEW YORK STATE: NY ZIP: 10014 BUSINESS PHONE: 646-597-6980 MAIL ADDRESS: STREET 1: 40 10TH AVENUE STREET 2: 7TH FLOOR CITY: NEW YORK STATE: NY ZIP: 10014 FORMER COMPANY: FORMER CONFORMED NAME: RTW INVESTMENTS, LLC DATE OF NAME CHANGE: 20100602 13F-HR 1 primary_doc.xml 13F-HR LIVE false true false 0001493215 XXXXXXXX 03-31-2021 03-31-2021 false RTW INVESTMENTS, LP

40 10TH AVENUE 7TH FLOOR NEW YORK NY 10014

13F HOLDINGS REPORT 028-16670 N Roderick Wong 646-597-6980 /s/ Roderick Wong New York NY 05-14-2021 3 111 6405753 1 0001493219 028-16671 RTW MASTER FUND, LTD. 2 0001776733 028-19525 RTW Innovation Master Fund Ltd. 3 0001785169 028-19571 RTW Venture Fund Ltd INFORMATION TABLE 2 infotable.xml 10x Genomics Inc CL A COM 88025U109 128784 711515 SH SOLE 1,2,3 711515 0 0 5 01 Acquisition Corp COM CL A 33836P105 3900 392000 SH SOLE 1,2,3 392000 0 0 908 Devices Inc COM 65443P102 1940 40000 SH SOLE 1,2,3 40000 0 0 Acutus Med Inc COM 005111109 6041 451834 SH SOLE 1,2,3 451834 0 0 Adverum Biotechnologies Inc COM 00773U108 72461 7348976 SH SOLE 1,2,3 7348976 0 0 Agenus Inc COM NEW 00847G705 37474 13777244 SH SOLE 1,2,3 13777244 0 0 Alnylam Pharmaceuticals Inc COM 02043Q107 237674 1683362 SH SOLE 1,2,3 1683362 0 0 Aptevo Therapeutics Inc COM NEW 03835L207 8588 281402 SH SOLE 1,2,3 281402 0 0 Apyx Medical Corporation COM 03837C106 32760 3391279 SH SOLE 1,2,3 3391279 0 0 Arbutus Biopharma Corp COM 03879J100 19908 5978355 SH SOLE 1,2,3 5978355 0 0 argenx SE SPONSORED ADR 04016X101 8744 31752 SH SOLE 1,2 31752 0 0 Arvinas Inc COM 04335A105 107267 1622799 SH SOLE 1,2,3 1622799 0 0 Arya Sciences Acquisition Co COM CL A G3166W106 6890 500000 SH SOLE 1,2,3 500000 0 0 Arya Sciences Acqu Corp IV CL A G31659108 5236 500000 SH SOLE 1,2,3 500000 0 0 Aslan Pharmaceuticals Ltd ADS 04522R101 10888 3250000 SH SOLE 1,2,3 3250000 0 0 Athira Pharma Inc COM 04746L104 48807 2652553 SH SOLE 1,2,3 2652553 0 0 Avadel Pharmaceuticals plc SPONSORED ADR 05337M104 51907 5741939 SH SOLE 1,2,3 5741939 0 0 Avidity Biosciences Inc COM 05370A108 87131 3995000 SH SOLE 1,2,3 3995000 0 0 Avita Medical Inc COM 05380C102 5550 280000 SH SOLE 1,2,3 280000 0 0 Axonics Modulation Technolog COM 05465P101 112825 1883864 SH SOLE 1,2,3 1883864 0 0 Axsome Therapeutics Inc COM 05464T104 91526 1616497 SH SOLE 1,2,3 1616497 0 0 Aziyo Biologics Inc COM CL A 05479K106 1728 125000 SH SOLE 1,2,3 125000 0 0 Bcls Acquisition Corp COM CL A G0904B105 6474 612500 SH SOLE 1,2,3 612500 0 0 BCTG Acquisition Corp COM 05492W103 6672 600000 SH SOLE 1,2,3 600000 0 0 Bellus Health Inc New COM NEW 07987C204 19040 4968017 SH SOLE 1,2,3 4968017 0 0 Berkeley Lts Inc COM 084310101 12937 257546 SH SOLE 1,2,3 257546 0 0 Bioatla Inc COM 09077B104 508 10000 SH SOLE 1,2,3 10000 0 0 Biodesix Inc COM 09075X108 2539 125000 SH SOLE 1,2,3 125000 0 0 Bolt Biotherapeutics Inc COM 097702104 4937 150000 SH SOLE 1,2,3 150000 0 0 Brainsway Ltd SPONSORED ADS 10501L106 14468 1602181 SH SOLE 1,2,3 1602181 0 0 Burning Rock Biotech Ltd SPONSORED ADS 12233L107 808 30000 SH SOLE 1,2,3 30000 0 0 C4 Therapeutics Inc COM STK 12529R107 79437 2149228 SH SOLE 1,2,3 2149228 0 0 Castle Biosciences Inc COM 14843C105 54700 799009 SH SOLE 1,2,3 799009 0 0 Celldex Therapeutics Inc New COM NEW 15117B202 80524 3908947 SH SOLE 1,2,3 3908947 0 0 Cerevel Therapeutics Hldng I COM 15678U128 6865 500000 SH SOLE 1,2,3 500000 0 0 Cerevel Therapeutics Hldng I *W EXP 06/09/202 15678U102 718 166666 SH SOLE 1,2,3 166666 0 0 Cerner Corp COM 156782104 127550 1774485 SH SOLE 1,2,3 1774485 0 0 Chardan Healthcr Acqstn 2 Co UNIT 99/99/9999 15957T206 3682 350000 SH SOLE 1,2,3 350000 0 0 Chardan Healthcr Acqstn 2 Co COM 15957T107 8417 837540 SH SOLE 1,2,3 837540 0 0 Clearside Biomedical Inc COM 185063104 10391 4206765 SH SOLE 1,2,3 4206765 0 0 Connect Biopharma Holdings Ltd ADS 207523101 8325 450000 SH SOLE 1,2,3 450000 0 0 Curis Inc COM NEW 231269200 40973 3619544 SH SOLE 1,2,3 3619544 0 0 Cytokinetics Inc COM NEW 23282W605 46520 2000000 SH SOLE 1,2,3 2000000 0 0 Cytomx Therapeutics Inc COM 23284F105 11856 1533758 SH SOLE 1,2,3 1533758 0 0 DermTech Inc COM 24984K105 158397 3118665 SH SOLE 1,2,3 3118665 0 0 Dicerna Pharmaceuticals Inc COM 253031108 190836 7463291 SH SOLE 1,2,3 7463291 0 0 Essa Pharma Inc COM NEW 29668H708 8241 283692 SH SOLE 1,2,3 283692 0 0 Establishment Labs Hldgs Inc COM G31249108 145016 2319138 SH SOLE 1,2,3 2319138 0 0 Exagen Inc COM 30068X103 28461 1626365 SH SOLE 1,2,3 1626365 0 0 Fulcrum Therapeutics Inc COM 359616109 37758 3205291 SH SOLE 1,2,3 3205291 0 0 Genetron Hldgs Ltd ADS 37186H100 39018 1818162 SH SOLE 1,2,3 1818162 0 0 Globus Med Inc CL A 379577208 103039 1670811 SH SOLE 1,2,3 1670811 0 0 Guardant Health Inc COM 40131M109 93082 609774 SH SOLE 1,2,3 609774 0 0 Helix Acquisition Corp COM CL A G4444C102 7658 750000 SH SOLE 1,2,3 750000 0 0 Ideaya Biosciences Inc COM 45166A102 57957 2466255 SH SOLE 1,2,3 2466255 0 0 Illumina Inc COM 452327109 185100 481956 SH SOLE 1,2,3 481956 0 0 Immatics N.V SHS N44445109 3924 350000 SH SOLE 1,2,3 350000 0 0 Immunic Inc COM 4525EP101 14678 920814 SH SOLE 1,2,3 920814 0 0 Immunocore Hldgs PLC ADS 45258D105 50142 1245532 SH SOLE 1,2,3 1245532 0 0 Immunovant Inc COM 45258J102 101962 6356743 SH SOLE 1,2,3 6356743 0 0 Inmode Ltd SHS M5425M103 9046 124999 SH SOLE 1,2 124999 0 0 Itamar Med Ltd SPONSORED ADS 465437101 6433 268609 SH SOLE 1,2,3 268609 0 0 Iteos Therapeutics Inc COM 46565G104 94432 2762791 SH SOLE 1,2,3 2762791 0 0 IVERIC bio Inc COM 46583P102 41546 6722624 SH SOLE 1,2,3 6722624 0 0 Johnson & Johnson COM 478160104 28029 170542 SH SOLE 1,2,3 170542 0 0 Kura Oncology Inc COM 50127T109 30586 1081912 SH SOLE 1,2,3 1081912 0 0 La Jolla Pharmaceutical Co COM PAR $.0001 2 503459604 9870 2327903 SH SOLE 1,2,3 2327903 0 0 Landos Biopharma Inc COM 515069102 38328 4275722 SH SOLE 1,2,3 4275722 0 0 Lifesci Acquisition Ii Corp COM 53229E103 6591 650000 SH SOLE 1,2,3 650000 0 0 MacroGenics Inc COM 556099109 64159 2014400 SH SOLE 1,2,3 2014400 0 0 Maravai Lifesciences Hldgs I COM CL A 56600D107 2495 70000 SH SOLE 1,2,3 70000 0 0 Masimo Corp COM 574795100 136638 594956 SH SOLE 1,2,3 594956 0 0 Medicus Sciences Acquisition UNIT 99/99/9999 G5960S116 2955 300000 SH SOLE 1,2,3 300000 0 0 Milestone Pharmaceuticals In COM 59935V107 24984 4315102 SH SOLE 1,2,3 4315102 0 0 MiMedx Group Inc COM 602496101 27813 2700320 SH SOLE 1,2,3 2700320 0 0 Mirati Therapeutics Inc COM 60468T105 228383 1333232 SH SOLE 1,2,3 1333232 0 0 NanoString Technologies Inc COM 63009R109 52833 804029 SH SOLE 1,2,3 804029 0 0 Natera Inc COM 632307104 173860 1712234 SH SOLE 1,2,3 1712234 0 0 Nuvation Bio Inc COM CL A 67080N101 3135 300000 SH SOLE 1,2,3 300000 0 0 Nuvation Bio Inc *W EXP 07/07/202 67080N119 267 100000 SH SOLE 1,2,3 100000 0 0 Olink Hldg AB SPONSORED ADS 680710100 6690 185838 SH SOLE 1,2,3 185838 0 0 Outset Med Inc COM 690145107 37374 687152 SH SOLE 1,2,3 687152 0 0 Oyster Pt Pharma Inc COM 69242L106 34023 1861209 SH SOLE 1,2,3 1861209 0 0 Personalis Inc COM 71535D106 3138 127501 SH SOLE 1,2 127501 0 0 Pmv Pharmaceuticals Inc COM 69353Y103 15923 484133 SH SOLE 1,2,3 484133 0 0 Profound Med Corp COM NEW 74319B502 2459 122098 SH SOLE 1,2,3 122098 0 0 Progenity Inc COM 74319F107 476 100000 SH SOLE 1,2,3 100000 0 0 Prometheus Biosciences Inc COM 74349U108 51727 3264031 SH SOLE 1,2,3 3264031 0 0 ProQR Thrapeutics N V SHS EURO N71542109 42463 6424078 SH SOLE 1,2,3 6424078 0 0 Protagonist Therapeutics Inc COM 74366E102 90841 3507390 SH SOLE 1,2,3 3507390 0 0 PTC Therapeutics Inc COM 69366J200 250669 5293966 SH SOLE 1,2,3 5293966 0 0 Pulmonx Corp COM 745848101 51668 1129600 SH SOLE 1,2,3 1129600 0 0 Quidel Corp COM 74838J101 112391 878533 SH SOLE 1,2,3 878533 0 0 Regenxbio Inc COM 75901B107 14209 416577 SH SOLE 1,2,3 416577 0 0 Relmada Therapeutics Inc COM 75955J402 53897 1530717 SH SOLE 1,2,3 1530717 0 0 Research Alliance Corp II COM CL A 760873109 6529 637000 SH SOLE 1,2,3 637000 0 0 Rocket Pharmaceuticals Inc COM 77313F106 697287 15715286 SH SOLE 1,2,3 15715286 0 0 Scholar Rock Holding Corp COM 80706P103 8187 161612 SH SOLE 1,2,3 161612 0 0 Seer Inc COM CL A 81578P106 200 4000 SH SOLE 1,2,3 4000 0 0 SPDR S&P 500 ETF TR TR UNIT 78462F103 375029 946255 SH SOLE 1,2,3 946255 0 0 Stoke Therapeutics Inc COM 86150R107 141543 3644248 SH SOLE 1,2,3 3644248 0 0 Tandem Diabetes Care Inc COM NEW 875372203 100537 1139230 SH SOLE 1,2,3 1139230 0 0 Tarsus Pharmaceuticals Inc. COM 87650L103 79091 2463601 SH SOLE 1,2,3 2463601 0 0 Tela Bio Inc COM 872381108 20597 1382343 SH SOLE 1,2,3 1382343 0 0 Therapeutics Acquisition Corp COM CL A 88339T103 5150 490000 SH SOLE 1,2,3 490000 0 0 Translate Bio Inc COM 89374L104 72262 4382199 SH SOLE 1,2,3 4382199 0 0 Trillium Therapeutics Inc COM NEW 89620X506 22462 2091389 SH SOLE 1,2,3 2091389 0 0 Twist Bioscience Corp COM 90184D100 2288 18473 SH SOLE 1,2,3 18473 0 0 Vericel Corp COM 92346J108 250951 4517570 SH SOLE 1,2,3 4517570 0 0 Vincerx Pharma Inc COM NEW 92731L106 9650 500000 SH SOLE 1,2,3 500000 0 0 Vincerx Pharma Inc wts $11.5 Exp. 12/24/2025 *W EXP 12/24/202 92731L114 2020 500000 SH SOLE 1,2,3 500000 0 0