0001493152-19-012319.txt : 20190814 0001493152-19-012319.hdr.sgml : 20190814 20190814085958 ACCESSION NUMBER: 0001493152-19-012319 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20190630 FILED AS OF DATE: 20190814 DATE AS OF CHANGE: 20190814 EFFECTIVENESS DATE: 20190814 FILER: COMPANY DATA: COMPANY CONFORMED NAME: RTW INVESTMENTS, LP CENTRAL INDEX KEY: 0001493215 IRS NUMBER: 000000000 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-16670 FILM NUMBER: 191023092 BUSINESS ADDRESS: STREET 1: 412 WEST 15TH STREET STREET 2: 9TH FLOOR CITY: NEW YORK STATE: NY ZIP: 10011 BUSINESS PHONE: 646-597-6980 MAIL ADDRESS: STREET 1: 412 WEST 15TH STREET STREET 2: 9TH FLOOR CITY: NEW YORK STATE: NY ZIP: 10011 FORMER COMPANY: FORMER CONFORMED NAME: RTW INVESTMENTS, LLC DATE OF NAME CHANGE: 20100602 13F-HR 1 primary_doc.xml 13F-HR LIVE false true false 0001493215 XXXXXXXX 06-30-2019 06-30-2019 false RTW INVESTMENTS, LP

412 West 15th Street 9th Floor New York NY 10011

13F HOLDINGS REPORT 028-16670 N Roderick Wong 646-597-6980 /s/ Roderick Wong New York NY 08-14-2019 3 52 1872337 1 0001493219 028-16671 RTW MASTER FUND, LTD. 2 0001776733 028-19525 RTW Innovation Master Fund Ltd. 3 0001785169 RTW Special Purpose Fund I, LLC INFORMATION TABLE 2 infotable.xml ACHILLION PHARMACEUTICALS IN COM 00448Q201 37157 13864383 SH SOLE 1,2 13864383 0 0 ADVERUM BIOTECHNOLOGIES INC COM 00773U108 75149 6320350 SH SOLE 1,2 6320350 0 0 AGENUS INC COM NEW 00847G705 30253 10084214 SH SOLE 1,2 10084214 0 0 ALNYLAM PHARMACEUTICALS INC COM 02043Q107 159494 2198094 SH SOLE 1,2 2198094 0 0 ANCHIANO THERAPEUTICS LTD SPONSORED ADS 03280X102 233 51918 SH SOLE 1,2 51918 0 0 APYX MED CORP COM 03837C106 22847 3399899 SH SOLE 1,2 3399899 0 0 ARBUTUS BIOPHARMA CORP COM 03879J100 11509 5533093 SH SOLE 1,2 5533093 0 0 ARGENX SE SPONSORED ADR 04016X101 4452 31448 SH SOLE 1,2 31448 0 0 ARROWHEAD PHARMACEUTICALS IN COM 04280A100 29689 1120346 SH SOLE 1,2 1120346 0 0 ARVINAS INC COM 04335A105 17765 807870 SH SOLE 1,2 807870 0 0 AXONICS MODULATION TECH INC COM 05465P101 62873 1534605 SH SOLE 1,2 1534605 0 0 AXSOME THERAPEUTICS INC COM 05464T104 21740 844289 SH SOLE 1,2 844289 0 0 BRAINSWAY LTD SPONSORED ADS 10501L106 6263 597216 SH SOLE 1,2 597216 0 0 BRISTOL MYERS SQUIBB CO COM 110122108 70833 1561918 SH SOLE 1,2 1561918 0 0 CAREDX INC COM 14167L103 5565 154616 SH SOLE 1,2 154616 0 0 CHARDAN HEALTHCARE ACQUISITI UNIT 12/13/2023 15957A207 6113 600000 SH SOLE 1,2 600000 0 0 CYTOMX THERAPEUTICS INC COM 23284F105 11089 988319 SH SOLE 1,2 988319 0 0 DICERNA PHARMACEUTICALS INC COM 253031108 96896 6152103 SH SOLE 1,2 6152103 0 0 ESTABLISHMENT LABS HLDGS INC COM G31249108 41411 1883180 SH SOLE 1,2 1883180 0 0 FLUIDIGM CORP DEL COM 34385P108 25594 2077471 SH SOLE 1,2 2077471 0 0 HOMOLOGY MEDICINES INC COM 438083107 40215 2054932 SH SOLE 1,2 2054932 0 0 ILLUMINA INC COM 452327109 30188 82000 SH SOLE 1,2 82000 0 0 JOHNSON & JOHNSON COM 478160104 13080 93912 SH SOLE 1,2 93912 0 0 LA JOLLA PHARMACEUTICAL CO COM PAR $.0001 2 503459604 18605 2011340 SH SOLE 1,2 2011340 0 0 MASIMO CORP COM 574795100 55399 372258 SH SOLE 1,2 372258 0 0 MILESTONE PHARMACEUTICALS IN COM 59935V107 90967 3521856 SH SOLE 1,2 3521856 0 0 MIRATI THERAPEUTICS INC COM 60468T105 26293 255270 SH SOLE 1,2 255270 0 0 MOTUS GI HLDGS INC COM 62014P108 3412 1126144 SH SOLE 1,2 1126144 0 0 MYOKARDIA INC COM 62857M105 36274 723455 SH SOLE 1,2 723455 0 0 MYRIAD GENETICS INC COM 62855J104 10462 376586 SH SOLE 1,2 376586 0 0 NEURONETICS INC COM 64131A105 2105 168274 SH SOLE 1,2 168274 0 0 ODONATE THERAPEUTICS INC COM 676079106 12444 339156 SH SOLE 1,2 339156 0 0 OPTINOSE INC COM 68404V100 620 87615 SH SOLE 1,2 87615 0 0 ORTHOPEDIATRICS CORP COM 68752L100 14689 376647 SH SOLE 1,2 376647 0 0 PERSONALIS INC COM 71535D106 6109 225000 SH SOLE 1,2 225000 0 0 PRINCIPIA BIOPHARMA INC COM 74257L108 8993 270948 SH SOLE 1,2 270948 0 0 PROQR THRAPEUTICS N V SHS EURO N71542109 33879 3722950 SH SOLE 1,2 3722950 0 0 PTC THERAPEUTICS INC COM 69366J200 141181 3137361 SH SOLE 1,2 3137361 0 0 QUOTIENT LTD SHS G73268107 14437 1544047 SH SOLE 1,2 1544047 0 0 REGENXBIO INC COM 75901B107 18906 368040 SH SOLE 1,2 368040 0 0 ROCKET PHARMACEUTICALS INC COM 77313F106 248812 16587491 SH SOLE 1,2,3 16587491 0 0 SAREPTA THERAPEUTICS INC COM 803607100 91814 604236 SH SOLE 1,2 604236 0 0 SILK ROAD MEDICAL INC COM 82710M100 10842 223722 SH SOLE 1,2 223722 0 0 SOLID BIOSCIENCES INC COM 83422E105 835 145225 SH SOLE 1,2 145225 0 0 STOKE THERAPEUTICS INC COM 86150R107 92570 3355466 SH SOLE 1,2 3355466 0 0 TRANSLATE BIO INC COM 89374L104 30808 2439250 SH SOLE 1,2 2439250 0 0 TRANSMEDICS GROUP INC COM 89377M109 14698 507007 SH SOLE 1,2 507007 0 0 UNIQURE NV SHS N90064101 11300 144595 SH SOLE 1,2 144595 0 0 VERICEL CORP COM 92346J108 49242 2606771 SH SOLE 1,2 2606771 0 0 VIEWRAY INC COM 92672L107 1403 159247 SH SOLE 1,2 159247 0 0 VIVEVE MED INC COM NEW 92852W204 1703 4480565 SH SOLE 1,2 4480565 0 0 Vivus Inc 4.5 05/01/2020 NOTE 4.500% 5/0 928551AA8 3128 4000000 SH SOLE 1 4000000 0 0