0001493152-16-010244.txt : 20160524 0001493152-16-010244.hdr.sgml : 20160524 20160524133923 ACCESSION NUMBER: 0001493152-16-010244 CONFORMED SUBMISSION TYPE: 13F-HR/A PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20151231 FILED AS OF DATE: 20160524 DATE AS OF CHANGE: 20160524 EFFECTIVENESS DATE: 20160524 FILER: COMPANY DATA: COMPANY CONFORMED NAME: RTW INVESTMENTS, LLC CENTRAL INDEX KEY: 0001493215 IRS NUMBER: 000000000 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR/A SEC ACT: 1934 Act SEC FILE NUMBER: 028-16670 FILM NUMBER: 161671379 BUSINESS ADDRESS: STREET 1: 250 WEST 55TH STREET STREET 2: 16TH FLOOR, SUITE A CITY: NEW YORK STATE: NY ZIP: 10019 BUSINESS PHONE: 646-597-6980 MAIL ADDRESS: STREET 1: 250 WEST 55TH STREET STREET 2: 16TH FLOOR, SUITE A CITY: NEW YORK STATE: NY ZIP: 10019 13F-HR/A 1 primary_doc.xml 13F-HR/A LIVE false true false 0001493215 XXXXXXXX 12-31-2015 12-31-2015 true 1 RESTATEMENT false RTW INVESTMENTS, LLC

250 WEST 55TH STREET 16TH FLOOR, SUITE A NEW YORK NY 10019

13F HOLDINGS REPORT 028-16670 N Roderick Wong 646-597-6980 /s/ Roderick Wong New York NY 05-24-2016 1 29 302757 1 0001493219 028-16671 RTW MASTER FUND, LTD. INFORMATION TABLE 2 infotable.xml Accelerate Diagnostics Inc COM 00430H102 2309 107467 SH SOLE 0 0 0 Achillion Pharmaceuticals Inc COM 00448Q201 21460 1988914 SH SOLE 0 0 0 Agenus Inc COM NEW 00847G705 10054 2214453 SH SOLE 0 0 0 Atara Biotherapeutics Inc. COM 046513107 11460 433923 SH SOLE 0 0 0 Berkshire Hathaway Inc CL B NEW 084670702 7 50 SH SOLE 0 0 0 Celldex Therapeutics Inc NEW COM 15117B103 9992 637238 SH SOLE 0 0 0 CytRx Corp COM PAR $.001 232828509 1247 470576 SH SOLE 0 0 0 Dicerna Pharmaceuticals Inc COM 253031108 23890 2012662 SH SOLE 0 0 0 Five Prime Therapeutics Inc COM 33830X104 10675 257236 SH SOLE 0 0 0 Kite Pharma Inc COM 49803L109 25815 418935 SH SOLE 0 0 0 Mirati Therapeutics Inc COM 60468T105 12180 385456 SH SOLE 0 0 0 NVRO 05/20/2016 PUT 50 COM 64157F103 37 142 SH Put SOLE 0 0 0 Omeros Corp COM 682143102 28618 1819341 SH SOLE 0 0 0 USO 01/15/2016 CALL 25 UNITS 91232N108 7 13850 SH Call SOLE 0 0 0 VIVO 01/15/2016 CALL 20 COM 589584101 110 1252 SH Call SOLE 0 0 0 Alnylam Pharmaceuticals Inc COM 02043Q107 53976 573361 SH SOLE 0 0 0 BioCryst Pharmaceuticals Inc COM 09058V103 20748 2010501 SH SOLE 0 0 0 Bristol-Myers Squibb Co COM 110122108 7546 109701 SH SOLE 0 0 0 Corium International Inc COM 21887L107 6040 743865 SH SOLE 0 0 0 Dyax Corp COM 26746E103 4356 115795 SH SOLE 0 0 0 Global Blood Therapeutics Inc ORD 37890U108 5663 175156 SH SOLE 0 0 0 Invuity Inc COM NEW 46187J205 1789 202808 SH SOLE 0 0 0 La Jolla Pharmaceutical Co COM PAR $.0001 2 503459604 29279 1084416 SH SOLE 0 0 0 Lipocine Inc NEW COM 53630X104 2851 220515 SH SOLE 0 0 0 Regenxbio Inc COM 75901B107 3674 221326 SH SOLE 0 0 0 Symmetry Surgical Inc COM 87159G100 8093 879623 SH SOLE 0 0 0 Adaptimmune Therapeutics-adr SPONDS ADR 00653A107 85 7055 SH SOLE 0 0 0 Biopharmx Corp COM 09072X101 563 370636 SH SOLE 0 0 0 Nivalis Therapeutics Inc COM 65481J109 232 30000 SH SOLE 0 0 0