0001214659-21-005410.txt : 20210514 0001214659-21-005410.hdr.sgml : 20210514 20210514160026 ACCESSION NUMBER: 0001214659-21-005410 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20210331 FILED AS OF DATE: 20210514 DATE AS OF CHANGE: 20210514 EFFECTIVENESS DATE: 20210514 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Sio Capital Management, LLC CENTRAL INDEX KEY: 0001482416 IRS NUMBER: 204586565 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-13691 FILM NUMBER: 21924360 BUSINESS ADDRESS: STREET 1: 600 THIRD AVENUE STREET 2: 2ND FLOOR CITY: NEW YORK STATE: NY ZIP: 10016 BUSINESS PHONE: 212-601-9786 MAIL ADDRESS: STREET 1: 600 THIRD AVENUE STREET 2: 2ND FLOOR CITY: NEW YORK STATE: NY ZIP: 10016 13F-HR 1 primary_doc.xml 13F-HR LIVE false false false 0001482416 XXXXXXXX 03-31-2021 03-31-2021 false Sio Capital Management, LLC

600 THIRD AVENUE 2ND FLOOR NEW YORK NY 10016

13F HOLDINGS REPORT 028-13691 N Jin W. Lee 212-601-9792 /s/ Jin W. Lee New York NY 05-14-2021 0 89 492663 INFORMATION TABLE 2 infotable.xml AFFIMED NV COM N01045108 4335 548044 SH SOLE 548044 0 0 AEGLEA BIO THERAPEUTICS INC COM 00773J103 3189 402653 SH SOLE 402653 0 0 ALPHA HEALTHCARE ACQUISITION CORP UNIT 09/21/2027 020751202 1250 100000 SH SOLE 100000 0 0 ALBIREO PHARMA INC COM 01345P106 9459 268346 SH SOLE 268346 0 0 AMN HEALTHCARE SERVICES INC COM 001744101 9131 123898 SH SOLE 123898 0 0 ANIKA THERAPEUTICS INC COM 035255108 1632 40000 SH SOLE 40000 0 0 APTOSE BIOSCIENCES INC COM NEW 03835T200 246 41100 SH SOLE 41100 0 0 ARDELYX INC COM 039697107 4771 720621 SH SOLE 720621 0 0 ARENA PHARMACEUTICALS INC COM NEW 040047607 1508 21738 SH SOLE 21738 0 0 ASGN INC COM 00191U102 3300 34577 SH SOLE 34577 0 0 ASLAN PHARMACEUTICALS LTD ADS 04522R101 4853 1448508 SH SOLE 1448508 0 0 AYALA PHARMACEUTICALS INC COM 05465V108 5346 489988 SH SOLE 489988 0 0 ATRECA INC CL A COM 04965G109 1739 113455 SH SOLE 113455 0 0 BIOLINE RX LTD SPONSORED ADS 09071M205 7650 2741776 SH SOLE 2741776 0 0 BIONANO GENOMICS INC COM 09075F107 196 24245 SH SOLE 24245 0 0 CARDINAL HEALTH INC COM 14149Y108 16701 274917 SH SOLE 274917 0 0 CASI PHARMACEUTICALS INC COM 14757U109 488 203432 SH SOLE 203432 0 0 CYMABAY THERAPEUTICS INC COM 23257D103 2553 562339 SH SOLE 562339 0 0 CATALYST BIOSCIENCES INC COM NEW 14888D208 3144 623892 SH SOLE 623892 0 0 CROSS COUNTRY HEALTHCARE INC COM 227483104 5411 433244 SH SOLE 433244 0 0 CERECOR INC COM 15671L109 1668 552241 SH SOLE 552241 0 0 CHARDAN HEALTHCARE ACQUISITION 2 CORP COM 15957T107 6410 600000 SH SOLE 600000 0 0 COHERUS BIOSCIENCES INC COM 19249H103 12387 847862 SH SOLE 847862 0 0 CIGNA CORP COM 125523100 25858 106965 SH SOLE 106965 0 0 CELLECTAR BIOSCIENCES INC COM PAR 15117F500 3523 2188058 SH SOLE 2188058 0 0 CENTENE CORP COM 15135B101 13900 217500 SH SOLE 217500 0 0 CONSTELLATION PHARMACEUTICALS INC COM 210373106 3887 166186 SH SOLE 166186 0 0 CURIS INC COM NEW 231269200 49600 4381668 SH SOLE 4381668 0 0 CEL-SCI CORP COM PAR NEW 150837607 10582 695700 SH Put SOLE 695700 0 0 DEERFIELD HEALTHCARE TECHNOLOGY ACQUISITIONS CORP UNIT 07/16/2025 244413209 655 50000 SH SOLE 50000 0 0 PRECISION BIOSCIENCES INC COM 74019P108 3409 329369 SH SOLE 329369 0 0 EMERGENT BIOSOLUTIONS INC COM 29089Q105 4646 50000 SH SOLE 50000 0 0 ESSA PHARMA INC COM NEW 29668H708 9084 312711 SH SOLE 312711 0 0 ETON PHARMACEUTICALS INC COM 29772L108 1191 162659 SH SOLE 162659 0 0 EUCRATES BIOMEDICAL ACQUISITION CORP. UNIT 10/23/2027 G3141W114 3004 300000 SH SOLE 300000 0 0 FREQUENCY THERAPEUTICS INC COM 35803L108 1549 163100 SH Put SOLE 163100 0 0 FULCRUM THERAPEUTICS INC COM 359616109 2253 191272 SH SOLE 191272 0 0 FUSION PHARMACEUTICALS INC COM 36118A100 2674 249419 SH SOLE 249419 0 0 SPDR GOLD SHARES GOLD SHS 78463V107 15518 97009 SH SOLE 97009 0 0 GLYCOMIMETICS INC COM 38000Q102 1070 355517 SH SOLE 355517 0 0 GOSSAMER BIO INC COM 38341P102 2418 261400 SH SOLE 261400 0 0 GLAXOSMITHKLINE PLC SPONSORED ADS 37733W105 9190 257500 SH SOLE 257500 0 0 HCA HEALTHCARE INC COM 40412C101 13781 73173 SH SOLE 73173 0 0 HERBALIFE NUTRITION LTD COM SHS G4412G101 6597 148719 SH SOLE 148719 0 0 HILL-ROM HOLDINGS INC COM 431475102 11893 107647 SH SOLE 107647 0 0 HARROW HEALTH INC COM 415858109 1415 209623 SH SOLE 209623 0 0 HEALTH SCIENCES ACQUISITIONS CORP 2 ORD SHS G4411D109 2798 250000 SH SOLE 250000 0 0 HORIZON THERAPEUTICS PLC SHS G46188101 5964 64801 SH SOLE 64801 0 0 ICON PLC SHS G4705A100 9328 47500 SH SOLE 47500 0 0 IDEAYA BIOSCIENCES INC COM 45166A102 1135 48298 SH SOLE 48298 0 0 I-MAB SPONSORED ADS 44975P103 727 15000 SH SOLE 15000 0 0 IOVANCE BIOTHERAPEUTICS INC COM 462260100 1407 44430 SH SOLE 44430 0 0 KURA ONCOLOGY INC COM 50127T109 6035 213471 SH SOLE 213471 0 0 ELI LILLY AND CO COM 532457108 1793 9600 SH Call SOLE 9600 0 0 LARIMAR THERAPEUTICS INC COM 517125100 2735 187223 SH SOLE 187223 0 0 MOLECULIN BIOTECH INC COM 60855D200 3929 963000 SH SOLE 963000 0 0 MCKESSON CORP COM 58155Q103 7586 38893 SH SOLE 38893 0 0 MEI PHARMA INC COM NEW 55279B202 1461 426047 SH SOLE 426047 0 0 MESOBLAST LTD SPONS ADR 590717104 468 56600 SH Put SOLE 56600 0 0 MACROGENICS INC COM 556099109 4141 130000 SH SOLE 130000 0 0 MIRUM PHARMACEUTICALS INC COM 604749101 8664 437138 SH SOLE 437138 0 0 MERCK & CO INC COM 58933Y105 9636 125000 SH SOLE 125000 0 0 MERSANA THERAPEUTICS INC COM 59045L106 2544 157259 SH SOLE 157259 0 0 NEUBASE THERAPEUTICS INC COM 64132K102 2909 393699 SH SOLE 393699 0 0 NEOLEUKIN THERAPEUTICS INC COM 64049K104 472 38312 SH SOLE 38312 0 0 NATUS MEDICAL INC COM 639050103 4340 169454 SH SOLE 169454 0 0 NOVAVAX INC COM NEW 670002401 4660 25700 SH SOLE 25700 0 0 ONCTERNAL THERAPEUTICS INC COM 68236P107 2690 323333 SH SOLE 323333 0 0 OSMOTICA PHARMACEUTICALS PLC SHS G6S41R101 1692 519039 SH SOLE 519039 0 0 PROQR THERAPEUTICS NV SHS EURO N71542109 2597 392821 SH SOLE 392821 0 0 RAPT THERAPEUTICS INC COM 75382E109 317 14298 SH SOLE 14298 0 0 RADIUS HEALTH INC COM NEW 750469207 4818 230957 SH SOLE 230957 0 0 RUBIUS THERAPEUTICS INC COM 78116T103 1585 59800 SH SOLE 59800 0 0 SIO GENE THERAPIES INC COM 829399104 1201 460248 SH SOLE 460248 0 0 SALARIUS PHARMACEUTICALS INC COM NEW 79400X107 4616 3118696 SH SOLE 3118696 0 0 SYNDAX PHARMACEUTICALS INC COM 87164F105 3268 146142 SH SOLE 146142 0 0 SOLITON INC COM 834251100 14492 824803 SH SOLE 824803 0 0 SPRUCE BIOSCIENCES INC COM 85209E109 13494 812884 SH SOLE 812884 0 0 SIERRA ONCOLOGY INC COM NEW 82640U404 1395 80952 SH SOLE 80952 0 0 SYNEOS HEALTH INC CL A 87166B102 4553 60025 SH SOLE 60025 0 0 TEVA PHARMACEUTICAL INDUSTRIES LTD SPONSORED ADS 881624209 6231 539947 SH SOLE 539947 0 0 TRILLIUM THERAPEUTICS INC COM NEW 89620X506 166 15500 SH SOLE 15500 0 0 UNIVERSAL HEALTH SERVICES INC CL B 913903100 9089 68135 SH SOLE 68135 0 0 UNITED THERAPEUTICS CORP COM 91307C102 9374 56044 SH SOLE 56044 0 0 VAPOTHERM INC COM 922107107 6203 258261 SH SOLE 258261 0 0 VINCERX PHARMA INC COM NEW 92731L106 2027 105000 SH SOLE 105000 0 0 VIKING THERAPEUTICS INC COM 92686J106 3604 569780 SH SOLE 569780 0 0 VERTEX PHARMACEUTICALS INC COM 92532F100 4527 21067 SH SOLE 21067 0 0 X4 PHARMACEUTICALS INC COM 98420X103 6928 804597 SH SOLE 804597 0 0