0001214659-18-007149.txt : 20181114 0001214659-18-007149.hdr.sgml : 20181114 20181114160040 ACCESSION NUMBER: 0001214659-18-007149 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20180930 FILED AS OF DATE: 20181114 DATE AS OF CHANGE: 20181114 EFFECTIVENESS DATE: 20181114 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Sio Capital Management, LLC CENTRAL INDEX KEY: 0001482416 IRS NUMBER: 204586565 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-13691 FILM NUMBER: 181183445 BUSINESS ADDRESS: STREET 1: 535 FIFTH AVENUE STREET 2: SUITE 910 CITY: NEW YORK STATE: NY ZIP: 10017 BUSINESS PHONE: 212-601-9786 MAIL ADDRESS: STREET 1: 535 FIFTH AVENUE STREET 2: SUITE 910 CITY: NEW YORK STATE: NY ZIP: 10017 13F-HR 1 primary_doc.xml 13F-HR LIVE false false false 0001482416 XXXXXXXX 09-30-2018 09-30-2018 false Sio Capital Management, LLC

535 FIFTH AVENUE SUITE 910 NEW YORK NY 10017

13F HOLDINGS REPORT 028-13691 N Albert Vigneau 212-601-9795 /s/Albert Vigneau New York NY 10-18-2018 0 64 291456 INFORMATION TABLE 2 infotable.xml ABBOTT LABORATORIES COM 002824100 1043 14220 SH DFND 0 14220 0 ACHIEVE LIFE SCIENCES INC COM NEW 004468203 523 165982 SH DFND 0 165982 0 AETNA INC COM 00817Y108 12261 60444 SH DFND 0 60444 0 AFFIMED NV COM N01045108 2426 557615 SH DFND 0 557615 0 AKCEA THERAPEUTICS INC PUT 00972L107 1516 43300 SH Put DFND 0 43300 0 ALEXION PHARMACEUTICALS INC COM 015351109 3584 25785 SH DFND 0 25785 0 ALLERGAN PLC PUT G0177J108 3333 17500 SH Put DFND 0 17500 0 ALNYLAM PHARMACEUTICALS INC COM 02043Q107 9117 104176 SH DFND 0 104176 0 AMAG PHARMACEUTICALS INC PUT 00163U106 4524 226200 SH Put DFND 0 226200 0 AMGEN INC CALL 031162100 4146 20000 SH Call DFND 0 20000 0 AMGEN INC PUT 031162100 10365 50000 SH Put DFND 0 50000 0 ANTHEM INC COM 036752103 6797 24803 SH DFND 0 24803 0 ARBUTUS BIOPHARMA CORP COM 03879J100 1559 164943 SH DFND 0 164943 0 ARROWHEAD PHARMACEUTICALS INC COM 04280A100 2190 114259 SH DFND 0 114259 0 ASTRAZENECA PLC PUT 046353108 3458 87400 SH Put DFND 0 87400 0 AXSOME THERAPEUTICS INC COM 05464T104 1437 416458 SH DFND 0 416458 0 BIOGEN INC COM 09062X103 6819 19300 SH DFND 0 19300 0 BIONANO GENOMICS INC COM 09075F107 5736 720377 SH DFND 0 720377 0 BIONANO GENOMICS INC *W EXP 08/21/2023 09075F107 1617 720480 SH DFND 0 720480 0 CARDINAL HEALTH INC COM 14149Y108 3348 62004 SH DFND 0 62004 0 CATALYST BIOSCIENCES INC COM NEW 14888D208 5940 550977 SH DFND 0 550977 0 CIGNA CORP COM 125509109 14046 67449 SH DFND 0 67449 0 CONFORMIS INC COM 20717E101 1973 1861789 SH DFND 0 1861789 0 DENTSPLY SIRONA INC PUT 24906P109 6416 170000 SH Put DFND 0 170000 0 ELECTROCORE, INC. COM 28531P103 1206 86120 SH DFND 0 86120 0 EMERGENT BIOSOLUTIONS INC COM 29089Q105 2752 41799 SH DFND 0 41799 0 ESTABLISHMENT LABS HOLDINGS INC COM G31249108 1077 44678 SH DFND 0 44678 0 FOAMIX PHARMACEUTICALS LTD SHS M46135105 4412 770000 SH DFND 0 770000 0 GLAXOSMITHKLINE PLC SPONSORED ADR 37733W105 14620 363960 SH DFND 0 363960 0 GTX INC PUT 40052B207 81 51500 SH Put DFND 0 51500 0 HCA HEALTHCARE INC COM 40412C101 11661 83822 SH DFND 0 83822 0 HILL-ROM HOLDINGS INC COM 431475102 2269 24036 SH DFND 0 24036 0 HUMANA INC COM 444859102 6789 20054 SH DFND 0 20054 0 ICON PLC SHS G4705A100 3567 23198 SH DFND 0 23198 0 KONINKLIJKE PHILIPS NV NY REG SH NEW 500472303 4359 95776 SH DFND 0 95776 0 KURA ONCOLOGY INC COM 50127T109 12727 727258 SH DFND 0 727258 0 LEXICON PHARMACEUTICALS INC PUT 528872302 230 21600 SH Put DFND 0 21600 0 MEDTRONIC PLC SHS G5960L103 3462 35196 SH DFND 0 35196 0 MEI PHARMA INC COM NEW 55279B202 9929 2303645 SH DFND 0 2303645 0 MERCK & CO INC CALL 58933Y105 5959 84000 SH Call DFND 0 84000 0 NEVRO CORP COM 64157F103 2570 45091 SH DFND 0 45091 0 NOVARTIS AG SPONSORED ADR 66987V109 4971 57691 SH DFND 0 57691 0 OPTINOSE INC COM 68404V100 336 27068 SH DFND 0 27068 0 PACIRA PHARMACEUTICALS INC PUT 695127100 13816 281100 SH Put DFND 0 281100 0 PFENEX INC COM 717071104 1092 213608 SH DFND 0 213608 0 PFIZER INC PUT 717081103 3151 71500 SH Put DFND 0 71500 0 PREMIER INC CL A 74051N102 6611 144412 SH DFND 0 144412 0 PUMA BIOTECHNOLOGY INC COM 74587V107 1505 32832 SH DFND 0 32832 0 RA MEDICAL SYSTEMS INC COM 74933X104 2467 135553 SH DFND 0 135553 0 REVANCE THERAPEUTICS INC COM 761330109 4084 164353 SH DFND 0 164353 0 RIGEL PHARMACEUTICALS INC COM NEW 766559603 5918 1843501 SH DFND 0 1843501 0 SANOFI SA SPONSORED ADR 80105N105 11900 266388 SH DFND 0 266388 0 SENSEONICS HOLDINGS INC COM 81727U105 1919 402408 SH DFND 0 402408 0 SMITH & NEPHEW PLC SPDN ADR NEW 83175M205 4984 134388 SH DFND 0 134388 0 SPECTRUM PHARMACEUTICALS INC COM 84763A108 1188 70712 SH DFND 0 70712 0 SUTRO BIOPHARMA INC COM 869367102 3488 232539 SH DFND 0 232539 0 TITAN MEDICAL INC COM NEW 88830X819 949 445680 SH DFND 0 445680 0 UNITEDHEALTH GROUP INC COM 91324P102 3347 12579 SH DFND 0 12579 0 UNIVERSAL HEALTH SERVICES INC CL B 913903100 5292 41393 SH DFND 0 41393 0 UROVANT SCIENCES LTD SHS G9381B108 7097 591454 SH DFND 0 591454 0 VICAL INC COM NEW 925602203 1699 1239813 SH DFND 0 1239813 0 VIKING THERAPEUTICS INC COM 92686J106 3715 213252 SH DFND 0 213252 0 VITAL THERAPIES INC COM 92847R104 29 103707 SH DFND 0 103707 0 VITAL THERAPIES INC PUT 92847R104 54 194700 SH Put DFND 0 194700 0