SEC Form 4

FORM 4		UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940	OMB APPROVAL OMB Number: 3235-0287 Estimated average burden hours per response: 0.5
X	Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

1. Name and Address of Reporting Person* Longitude Capital Partners, LLC (Last) (First) (Middle) 800 EL CAMINO REAL, SUITE 220 (Street) MENLO PARK CA 94025 (City) (State) (Zip)	2. Issuer Name and Ticker or Trading Symbol Esperion Therapeutics, Inc. [ ESPR ]	5. Relationship of Reporting Person(s) to Issuer (Check all applicable) Director X 10% Owner Officer (give title below) Other (specify below)
	3. Date of Earliest Transaction (Month/Day/Year) 11/17/2014
	4. If Amendment, Date of Original Filed (Month/Day/Year)	6. Individual or Joint/Group Filing (Check Applicable Line) Form filed by One Reporting Person X Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	11/17/2014		S		200,591	D	$32.0115(1)	1,683,178	I	By LVP(11)
Common Stock	11/17/2014		S		136,148	D	$32.9339(2)	1,547,030	I	By LVP(11)
Common Stock	11/17/2014		S		135,816	D	$33.7897(3)	1,411,214	I	By LVP(11)
Common Stock	11/17/2014		S		4,021	D	$32.0115(4)	33,736	I	By LCA(11)
Common Stock	11/17/2014		S		2,728	D	$32.9339(5)	31,008	I	By LCA(11)
Common Stock	11/17/2014		S		2,722	D	$33.7896(6)	28,286	I	By LCA(1)
Common Stock	11/18/2014		S		4,592	D	$31.5644(7)	1,406,622	I	By LVP(11)
Common Stock	11/18/2014		S		412	D	$32.1377(8)	1,406,210	I	By LVP(11)
Common Stock	11/18/2014		S		92	D	$31.5666(9)	28,194	I	By LCA(11)
Common Stock	11/18/2014		S		8	D	$32.1313(10)	28,186	I	By LCA(11)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

1. Name and Address of Reporting Person* Longitude Capital Partners, LLC (Last) (First) (Middle) 800 EL CAMINO REAL, SUITE 220 (Street) MENLO PARK CA 94025 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* Longitude Capital Associates, L.P. (Last) (First) (Middle) C/O LONGITUDE CAPITAL PARTNERS, LLC 800 EL CAMINO REAL, SUITE 220 (Street) MENLO PARK CA 94025 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* Longitude Venture Partners L.P. (Last) (First) (Middle) C/O LONGITUDE CAPITAL PARTNERS, LLC 800 EL CAMINO REAL, SUITE 220 (Street) MENLO PARK CA 94025 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* Tammenoms Bakker Juliet (Last) (First) (Middle) C/O LONGITUDE CAPITAL PARTNERS, LLC 800 EL CAMINO REAL, SUITE 220 (Street) MENLO PARK CA 94025 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

Explanation of Responses:

1. Reflects sales of Common Stock of the Issuer executed in multiple transactions at prices ranging from $31.52 to $32.51. The price reported reflects the weighted average sale price. Each Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected.

2. Reflects sales of Common Stock of the Issuer executed in multiple transactions at prices ranging from $32.52 to $33.5150. The price reported reflects the weighted average sale price. Each Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected.

3. Reflects sales of Common Stock of the Issuer executed in multiple transactions at prices ranging from $33.52 to $34.42. The price reported reflects the weighted average sale price. Each Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected.

4. Reflects sales of Common Stock of the Issuer executed in multiple transactions at prices ranging from $31.52 to $32.51. The price reported reflects the weighted average sale price. Each Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected.

5. Reflects sales of Common Stock of the Issuer executed in multiple transactions at prices ranging from $32.52 to $33.5150. The price reported reflects the weighted average sale price. Each Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected.

6. Reflects sales of Common Stock of the Issuer executed in multiple transactions at prices ranging from $33.52 to $34.42. The price reported reflects the weighted average sale price. Each Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected.

7. Reflects sales of Common Stock of the Issuer executed in multiple transactions at prices ranging from $31.08 to $32.01. The price reported reflects the weighted average sale price. Each Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected.

8. Reflects sales of Common Stock of the Issuer executed in multiple transactions at prices ranging from $32.09 to $32.26. The price reported reflects the weighted average sale price. Each Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected.

9. Reflects sales of Common Stock of the Issuer executed in multiple transactions at prices ranging from $31.08 to $32.01. The price reported reflects the weighted average sale price. Each Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected.

10. Reflects sales of Common Stock of the Issuer executed in multiple transactions at prices ranging from $32.09 to $32.26. The price reported reflects the weighted average sale price. Each Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected.

11. This report is filed jointly by Longitude Capital Partners, LLC ("LCP"), Longitude Venture Partners, L.P. ("LVP"), Longitude Capital Associates, L.P. ("LCA") and Juliet Tammenoms Bakker ("Bakker"), all of whom share beneficial ownership of more than 10% of the capital stock of the Issuer. LCP, as the general partner of each of LVP and LCA, has the power to vote and dispose of securities held by each of them. Patrick G. Enright, who serves on the Board of Directors of the Issuer and files separate Section 16 reports relating to the Issuer, and Bakker are each managing members of LCP and, as such, may be deemed to beneficially own the shares held by LVP and LCA. Each of LCP and Bakker disclaims beneficial ownership of the securities of the Issuer held by LVP and LCA except to the extent of their respective pecuniary interest therein.

Remarks:

All of the sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan.

	/s/ Juliet Tammenoms Bakker	11/19/2014
	/s/ Patrick G. Enright, as managing member of Longitude Capital Partners, LLC	11/19/2014
	/s/ Patrick G. Enright, as managing member of Longitude Capital Partners, LLC, as general partner of Longitude Venture Partners, L.P.	11/19/2014
	/s/ Patrick G. Enright, as managing member of Longitude Capital Partners, LLC, as general partner of Longitude Capital Associates, L.P.	11/19/2014
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
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