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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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<SEC-DOCUMENT>0001209191-10-016008.txt : 20100310
<SEC-HEADER>0001209191-10-016008.hdr.sgml : 20100310
<ACCEPTANCE-DATETIME>20100310163350
ACCESSION NUMBER:		0001209191-10-016008
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20100308
FILED AS OF DATE:		20100310
DATE AS OF CHANGE:		20100310

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Ferre Maurice R
		CENTRAL INDEX KEY:			0001424207

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-33966
		FILM NUMBER:		10670934

	MAIL ADDRESS:	
		STREET 1:		C/O MAKO SURGICAL CORP.
		STREET 2:		2555 DAVIE ROAD
		CITY:			FORT LAUDERDALE
		STATE:			FL
		ZIP:			33317

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			MAKO Surgical Corp.
		CENTRAL INDEX KEY:			0001411861
		STANDARD INDUSTRIAL CLASSIFICATION:	ORTHOPEDIC, PROSTHETIC & SURGICAL APPLIANCES & SUPPLIES [3842]
		IRS NUMBER:				201901148
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		2555 DAVIE ROAD
		CITY:			FT. LAUDERDALE
		STATE:			FL
		ZIP:			33317
		BUSINESS PHONE:		954-927-2044

	MAIL ADDRESS:	
		STREET 1:		2555 DAVIE ROAD
		CITY:			FT. LAUDERDALE
		STATE:			FL
		ZIP:			33317
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>doc4.xml
<DESCRIPTION>FORM 4 SUBMISSION
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2010-03-08</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001411861</issuerCik>
        <issuerName>MAKO Surgical Corp.</issuerName>
        <issuerTradingSymbol>MAKO</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001424207</rptOwnerCik>
            <rptOwnerName>Ferre Maurice R</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O MAKO SURGICAL CORP.</rptOwnerStreet1>
            <rptOwnerStreet2>2555 DAVIE ROAD</rptOwnerStreet2>
            <rptOwnerCity>FT. LAUDERDALE</rptOwnerCity>
            <rptOwnerState>FL</rptOwnerState>
            <rptOwnerZipCode>33317</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>President, CEO and Chairman</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2010-03-08</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F1"/>
            </transactionCoding>
            <transactionTimeliness>
                <value></value>
            </transactionTimeliness>
            <transactionAmounts>
                <transactionShares>
                    <value>10000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>14.0023</value>
                    <footnoteId id="F2"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>842178</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 27, 2009 and modified on August 24, 2009 for the sale of up to 100,000 shares of common stock.  The plan was previously disclosed in a Form 8-K filed with the Securities and Exchange Commission on May 28, 2009.</footnote>
        <footnote id="F2">The price in Column 4 is a weighted average price per share. The shares were sold in multiple transasctions at prices ranging from $14.00 per share to $14.03 per share. The reporting person will provide to the issuer, any security holder of the issuer or the staff of the Securities and Exchange Commission, upon request, information regarding the number of shares sold at each price within the range.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ Menashe R. Frank, attorney in fact</signatureName>
        <signatureDate>2010-03-10</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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