-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
 G/rKdNolxw/d9fj0TAqBhroi/0BJ8+QJ4ttifJGmSuMpomoRfb6+VOFQqeOnTij/
 Y6h0OLg/8uR2QwC6+FWn2Q==

<SEC-DOCUMENT>0000909518-10-000267.txt : 20100416
<SEC-HEADER>0000909518-10-000267.hdr.sgml : 20100416
<ACCEPTANCE-DATETIME>20100416175254
ACCESSION NUMBER:		0000909518-10-000267
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20100415
FILED AS OF DATE:		20100416
DATE AS OF CHANGE:		20100416

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Schiano Dominick
		CENTRAL INDEX KEY:			0001405548

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-34529
		FILM NUMBER:		10755747

	MAIL ADDRESS:	
		STREET 1:		30275 OAKLEAF LANE
		CITY:			FRANKLIN
		STATE:			MI
		ZIP:			48025

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			STR Holdings, Inc.
		CENTRAL INDEX KEY:			0001473597
		STANDARD INDUSTRIAL CLASSIFICATION:	UNSUPPORTED PLASTICS FILM & SHEET [3081]
		IRS NUMBER:				271023344
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		10 WATER STREET
		CITY:			ENFIELD
		STATE:			CT
		ZIP:			06082
		BUSINESS PHONE:		860-749-8371

	MAIL ADDRESS:	
		STREET 1:		10 WATER STREET
		CITY:			ENFIELD
		STATE:			CT
		ZIP:			06082

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	STR Holdings (New) LLC
		DATE OF NAME CHANGE:	20091001
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>schiano_form4ex.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2010-04-15</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001473597</issuerCik>
        <issuerName>STR Holdings, Inc.</issuerName>
        <issuerTradingSymbol>STRI</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001405548</rptOwnerCik>
            <rptOwnerName>Schiano Dominick</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>10 WATER STREET</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>ENFIELD</rptOwnerCity>
            <rptOwnerState>CT</rptOwnerState>
            <rptOwnerZipCode>06082</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock, par value $0.01 per share</value>
            </securityTitle>
            <transactionDate>
                <value>2010-04-15</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>47699</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>18.75</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>157917</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <ownerSignature>
        <signatureName>/s/ Joseph C. Radziewicz, Attorney-in-Fact</signatureName>
        <signatureDate>2010-04-16</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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