SEC FORM 3

SEC Form 3

FORM 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person^*

Martin Hugh C

(Last)

(First)

(Middle)

PACIFIC BIOSCIENCES OF CALIFORNIA, INC.

1380 WILLOW ROAD

(Street)

MENLO PARK

94025

(City)

(State)

(Zip)

2. Date of Event Requiring Statement (Month/Day/Year)
10/26/2010

3. Issuer Name and Ticker or Trading Symbol
PACIFIC BIOSCIENCES OF CALIFORNIA INC [ PACB ]

4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director	10% Owner
X	Officer (give title below)	Other (specify below)
	Chairman, CEO & President

5. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1. Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)
Common Stock	342,458	D
Common Stock	417,901	I	By Trust⁽¹⁾

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 4)	2. Date Exercisable and Expiration Date (Month/Day/Year)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
1. Title of Derivative Security (Instr. 4)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares	4. Conversion or Exercise Price of Derivative Security	5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
Stock Option (right to buy)	⁽²⁾	09/08/2015	Common Stock	52,412	$0.7	D
Stock Option (right to buy)	⁽³⁾	06/21/2017	Common Stock	38,835	$1.96	D
Stock Option (right to buy)	⁽⁴⁾	06/21/2017	Common Stock	100,133	$1.96	D
Stock Option (right to buy)	⁽⁵⁾	03/19/2019	Common Stock	505,891	$3.86	D
Stock Option (right to buy)	⁽⁶⁾	02/17/2020	Common Stock	142,395	$8.5	D
Stock Option (right to buy)	⁽⁷⁾	08/12/2020	Common Stock	250,000	$13.42	D

Explanation of Responses:

1. Shares are held by Hugh Martin Trust UAD 07/14/09, of which the Reporting Person is the sole trustee.

2. 100% of the shares subject to the option are fully vested and exercisable.

3. 1/5 of the shares subject to the original option of 231,991 shares vested on June 1, 2008, and the remaining shares have vested and will vest monthly thereafter, such that 100% of the shares subject to the original option will be fully vested on June 1, 2012. All shares subject to the option are early exercisable.

4. 1/5 of the shares subject to the original option of 100,133 shares vested on June 1, 2008, and the remaining shares have vested and will vest monthly thereafter, such that 100% of the shares subject to the original option will be fully vested on June 1, 2012. All shares subject to the option are early exercisable.

5. 1/5 of the shares subject to the original option of 550,000 shares vested on January 1, 2010, and the remaining shares have vested and will vest monthly thereafter, such that 100% of the shares subject to the original option will be fully vested on January 1, 2014. All shares subject to the option are early exercisable.

6. 1/5 of the shares subject to the original option of 150,000 shares vested on June 1, 2010, and the remaining shares have vested and will vest monthly thereafter, such that 100% of the shares subject to the original option will be fully vested on June 1, 2014. All shares subject to the option are early exercisable.

7. 1/4 of the shares subject to the option will vest on August 12, 2011, and the remaining shares will vest monthly thereafter, such that 100% of the shares subject to the option will be fully vested on August 12, 2014. All shares subject to the option are early exercisable.

	Brian Dow, Attorney-in-fact for Hugh C. Martin	10/26/2010
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
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