-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 MS8oEb5B7a15c1fhYKUpDSdMd99OscbNkMgf/ftIt45WHTkj+ZjjFAyrXYVvw+cE
 UHo3W9PsLeRIPK6r4jfHOQ==

<SEC-DOCUMENT>0001140361-10-038330.txt : 20100923
<SEC-HEADER>0001140361-10-038330.hdr.sgml : 20100923
<ACCEPTANCE-DATETIME>20100923121709
ACCESSION NUMBER:		0001140361-10-038330
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20100921
FILED AS OF DATE:		20100923
DATE AS OF CHANGE:		20100923

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Spence David R
		CENTRAL INDEX KEY:			0001501946

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-52588
		FILM NUMBER:		101086209

	MAIL ADDRESS:	
		STREET 1:		10401 CLAYTON ROAD
		CITY:			FRONTENAC
		STATE:			MO
		ZIP:			63131

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Reliance Bancshares, Inc.
		CENTRAL INDEX KEY:			0001397771
		STANDARD INDUSTRIAL CLASSIFICATION:	NATIONAL COMMERCIAL BANKS [6021]
		IRS NUMBER:				431823071
		STATE OF INCORPORATION:			MO
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		10401 CLAYTON ROAD
		CITY:			FRONTENAC
		STATE:			MO
		ZIP:			63131
		BUSINESS PHONE:		314-569-7200

	MAIL ADDRESS:	
		STREET 1:		10401 CLAYTON ROAD
		CITY:			FRONTENAC
		STATE:			MO
		ZIP:			63131
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>doc1.xml
<DESCRIPTION>FORM 4
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2010-09-21</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001397771</issuerCik>
        <issuerName>Reliance Bancshares, Inc.</issuerName>
        <issuerTradingSymbol>RLBS</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001501946</rptOwnerCik>
            <rptOwnerName>Spence David R</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>10401 CLAYTON ROAD</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>FRONTENAC</rptOwnerCity>
            <rptOwnerState>MO</rptOwnerState>
            <rptOwnerZipCode>63131</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle></officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Class A Common</value>
            </securityTitle>
            <transactionDate>
                <value>2010-09-21</value>
            </transactionDate>
            <deemedExecutionDate>
                <value>2010-09-21</value>
            </deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>P</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>500000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>3.00</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>588824</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <derivativeTable></derivativeTable>

    <footnotes></footnotes>

    <remarks>Purchase subject to earlier Subscription during open trading.</remarks>

    <ownerSignature>
        <signatureName>/s/ David R. Spence</signatureName>
        <signatureDate>2010-09-23</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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