SEC Form 3

FORM 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person* Wolf Jeffrey Alan (Last) (First) (Middle) C/O 100 EUROPA DRIVE (Street) CHAPEL HILL NC 27517 (City) (State) (Zip)	2. Date of Event Requiring Statement (Month/Day/Year) 07/23/2013	3. Issuer Name and Ticker or Trading Symbol HEAT BIOLOGICS, INC. [ HTBX ]
		4. Relationship of Reporting Person(s) to Issuer (Check all applicable) X Director X 10% Owner X Officer (give title below) Other (specify below) Chief Executive Officer	5. If Amendment, Date of Original Filed (Month/Day/Year)
			6. Individual or Joint/Group Filing (Check Applicable Line) Form filed by One Reporting Person X Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1. Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)
Common Stock	695,653(1)(2)	I	By Orion Holdings V, LLC(3)
Common Stock	536,862(1)(2)	I	By Seed-One Holdings VI, LLC(3)

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 4)	2. Date Exercisable and Expiration Date (Month/Day/Year)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Options	12/18/2009	12/17/2019	Common Stock	10,965(4)	$2.3	D
Options	12/18/2009	12/17/2019	Common Stock	108,696(4)	$0.71	D
Series B Preferred Stock	(5)	(5)	Common Stock	1,160(5)	(5)	D

1. Name and Address of Reporting Person* Wolf Jeffrey Alan (Last) (First) (Middle) C/O 100 EUROPA DRIVE (Street) CHAPEL HILL NC 27517 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer X Director X 10% Owner X Officer (give title below) Other (specify below) Chief Executive Officer

1. Name and Address of Reporting Person* Orion Holdings V, LLC (Last) (First) (Middle) C/O 100 EUROPA DRIVE (Street) CHAPEL HILL NC 27517 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* Seed-One Holdings VI, LLC (Last) (First) (Middle) C/O 100 EUROPA DRIVE (Street) CHAPEL HILL NC 27517 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

Explanation of Responses:

1. Does not include 86,957 shares of common stock beneficially owned by Mr. Wolf's children's trust which Mr. Wolf is not the trustee of. Mr. Wolf disclaims beneficial ownership of these shares except to the extent of any pecuniary interest (as defined in Rule 16a - 1(a)(2) promulgated under the Exchange Act) that he may have in such entities.

2. Does not include shares of common stock that will be issued upon consummation of the Company's initial public offering resulting in net proceeds of at least $15 million in lieu of Series B-2 Preferred Stock that was committed to be purchased upon receipt of certain grant funding and the shares underlying warrants to be issued at such time.

3. Mr. Wolf serves as the managing member. Mr. Wolf is deemed to beneficially own the shares held by such entities as in his role as the managing member he has the control over the voting and disposition of any shares held by these entities.

4. Fully Vested.

5. The Series B Preferred Stock automatically converts into shares of common stock to be issued upon consummation of the Company's initial public offering resulting in net proceeds of at least $15 million.

	/s/ Jeffrey Wolf	07/23/2013
	/s/ Jeffrey Wolf, Managing Member Orion Holdings V, LLC	07/23/2013
	/s/ Jeffrey Wolf, Managing Member of Seed-One Holdings V, LLC	07/23/2013
	** Signature of Reporting Person	Date
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