NUVEEN INVESTMENT TRUST V

AMENDED AND RESTATED DESIGNATION OF SERIES OF

SHARES OF BENEFICIAL INTEREST

WHEREAS, pursuant to Section 2 of Article IV of the Declaration of Trust dated September 27, 2006 (the “Declaration”), of Nuveen Investment Trust V, a Massachusetts business trust (the “Trust”), the Trustees of the Trust, on September 27, 2006 established and designated one series of Shares (as defined in the Declaration) of the Trust by the execution of instruments establishing and designating such series and setting forth the special and relative rights of such series (the “Designation”). Such series was entitled: Nuveen Preferred Securities Fund;

WHEREAS, the Trustees of the Trust, effective August 24, 2009, amended and restated the Designation to establish and designate one additional series of Shares, Nuveen NWQ Preferred Securities Fund;

WHEREAS, the Trustees of the Trust, effective March 12, 2012, changed the name of the Nuveen NWQ Preferred Securities Fund to Nuveen NWQ Flexible Income Fund;

WHEREAS, the Trustees of the Trust, effective April 18, 2012, amended and restated the Designation to establish and designate two additional series of Shares, Nuveen Gresham Diversified Commodity Strategy Fund and Nuveen Gresham Long/Short Commodity Strategy Fund;

WHEREAS, the Trustees of the Trust, effective May 26, 2016, established and designated two additional series of Shares, Nuveen Multi-Asset Income Fund and Nuveen Multi-Asset Income Tax-Aware Fund;

WHEREAS, on April 24, 2017 Nuveen Gresham Long/Short Commodity Strategy Fund was liquidated and terminated as a series of the Trust pursuant to approval by the Trustees at meetings held February 21-23, 2017;

WHEREAS, the Trustees of the Trust, effective September 29, 2017, amended and restated the Designation, to change the name of the series designated Nuveen Preferred Securities Fund to Nuveen Preferred Securities and Income Fund;

-2-

WHEREAS, the Trustees of the Trust, effective December 14, 2017, amended and restated the Designation, to establish and designate an additional series of Shares, Nuveen Global Real Estate Securities Fund;

WHEREAS, the Trustees of the Trust, effective March 15, 2018, amended and restated the Designation, to establish and designate an additional series of Shares, Nuveen Gresham Managed Futures Strategy Fund;

WHEREAS, on September 15, 2018 Nuveen Multi-Asset Income Tax Aware Fund was liquidated and terminated as a series of the Trust pursuant to approval by the Trustees at meetings held August 7-9, 2018;

WHEREAS, on May 17, 2019 Nuveen Multi-Asset Income Fund was liquidated and terminated as a series of the Trust pursuant to approval by the Trustees at meetings held April 17-18, 2019;

WHEREAS, on July 24, 2020 Nuveen Gresham Diversified Commodity Strategy Fund was liquidated and terminated as a series of the Trust pursuant to approval by the Trustees at meetings held May 18-21, 2020; and

WHEREAS, on November 20, 2020 Nuveen Gresham Managed Futures Strategy Fund was liquidated and terminated as a series of the Trust pursuant to approval by the Trustees at a meeting held September 22, 2020;

WHEREAS, the Trustees of the Trust, effective December 31, 2021, desire to amend and restate the Designation solely to change the name of the series designated Nuveen NWQ Flexible Income Fund to Nuveen Flexible Income Fund;

NOW THEREFORE, the Trustees of the Trust, effective December 31, 2021, hereby amend and restate the Designation as follows:

1. The following Funds are established and designated:

Nuveen Global Real Estate Securities Fund

Nuveen Flexible Income Fund

Nuveen Preferred Securities and Income Fund

-3-

2.        Each Fund shall be authorized to hold cash, invest in securities, instruments and other property and use investment techniques as from time to time described in the Trust’s then currently effective registration statement under the Securities Act of 1933 to the extent pertaining to the offering of Shares of such Fund. Each Share of each Fund shall be redeemable, shall be entitled to one vote (or fraction thereof in respect of a fractional share) on matters on which Shareholders of that Fund may vote in accordance with the Declaration, shall represent a pro rata beneficial interest in the assets allocated or belonging to such Fund, and shall be entitled to receive its pro rata share of the net assets of such Fund upon liquidation of such Fund, all as provided in Article IV, Sections 2 and 5 of the Declaration. The proceeds of the sale of Shares of such Fund, together with any income and gain thereon, less any diminution or expenses thereof, shall irrevocably belong to such Fund, unless otherwise required by law.

3.        Shareholders of each Fund shall vote separately as a class on any matter to the extent required by, and any matter shall be deemed to have been effectively acted upon with respect to such Fund as provided in Rule 18f-2, as from time to time in effect, under the Investment Company Act of 1940, as amended, or any successor rules, and by the Declaration.

4.        The assets and liabilities of the Trust shall be allocated among each Fund as set forth in Article IV, Section 5 of the Declaration.

5.        The designation of the Fund hereby shall not impair the power of the Trustees from time to time to designate additional series of Shares of the Trust.

6.        Subject to the applicable provisions of the 1940 Act and the provisions of Article IV, Sections 2 and 5 of the Declaration, the Trustees shall have the right at any time and from time to time to reallocate assets and expenses or to change the designation of each Fund now or hereafter created, or to otherwise change the special relative rights of the Funds designated hereby without any action or consent of the Shareholders.

-4-

        IN WITNESS WHEREOF, the undersigned, being a majority of the Trustees of the Trust, have executed this instrument as of this 7^th day of December, 2021.

/s/ Jack B. Evans	/s/ William C. Hunter
Jack B. Evans,	William C. Hunter,
as Trustee	as Trustee
333 West Wacker Drive	333 West Wacker Drive
Chicago, Illinois 60606	Chicago, Illinois 60606
/s/ Amy B.R. Lancellotta	/s/ Joanne T. Medero
Amy B.R. Lancellotta,	Joanne T. Medero,
as Trustee	as Trustee
333 West Wacker Drive	333 West Wacker Drive
Chicago, Illinois 60606	Chicago, Illinois 60606
/s/ Albin F. Moschner	/s/ John K. Nelson
Albin F. Moschner,	John K. Nelson,
as Trustee	as Trustee
333 West Wacker Drive	333 West Wacker Drive
Chicago, Illinois 60606	Chicago, Illinois 60606
/s/ Judith M. Stockdale
Judith M. Stockdale,	Carole E. Stone,
as Trustee	as Trustee
333 West Wacker Drive	333 West Wacker Drive
Chicago, Illinois 60606	Chicago, Illinois 60606
/s/ Matthew Thornton III	/s/ Terence J. Toth
Matthew Thornton III,	Terence J. Toth,
as Trustee	as Trustee
333 West Wacker Drive	333 West Wacker Drive
Chicago, Illinois 60606	Chicago, Illinois 60606
/s/ Margaret L. Wolff	/s/ Robert L. Young
Margaret L. Wolff,	Robert L. Young,
as Trustee	as Trustee
333 West Wacker Drive	333 West Wacker Drive
Chicago, Illinois 60606	Chicago, Illinois 60606

-5-

        IN WITNESS WHEREOF, the undersigned, being a majority of the Trustees of the Trust, have executed this instrument as of this 8^th day of December, 2021.

Jack B. Evans,	William C. Hunter,
as Trustee	as Trustee
333 West Wacker Drive	333 West Wacker Drive
Chicago, Illinois 60606	Chicago, Illinois 60606
Amy B.R. Lancellotta,	Joanne T. Medero,
as Trustee	as Trustee
333 West Wacker Drive	333 West Wacker Drive
Chicago, Illinois 60606	Chicago, Illinois 60606
Albin F. Moschner,	John K. Nelson,
as Trustee	as Trustee
333 West Wacker Drive	333 West Wacker Drive
Chicago, Illinois 60606	Chicago, Illinois 60606
	/s/ Carole E. Stone
Judith M. Stockdale,	Carole E. Stone,
as Trustee	as Trustee
333 West Wacker Drive	333 West Wacker Drive
Chicago, Illinois 60606	Chicago, Illinois 60606
Matthew Thornton III,	Terence J. Toth,
as Trustee	as Trustee
333 West Wacker Drive	333 West Wacker Drive
Chicago, Illinois 60606	Chicago, Illinois 60606
Margaret L. Wolff,	Robert L. Young,
as Trustee	as Trustee
333 West Wacker Drive	333 West Wacker Drive
Chicago, Illinois 60606	Chicago, Illinois 60606