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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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<SEC-DOCUMENT>0001019687-10-004272.txt : 20101201
<SEC-HEADER>0001019687-10-004272.hdr.sgml : 20101201
<ACCEPTANCE-DATETIME>20101201140346
ACCESSION NUMBER:		0001019687-10-004272
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20101129
FILED AS OF DATE:		20101201
DATE AS OF CHANGE:		20101201

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Janus Jeffrey
		CENTRAL INDEX KEY:			0001382694

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-51891
		FILM NUMBER:		101224368

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		310 454-3055

	MAIL ADDRESS:	
		STREET 1:		2595 JASON COURT
		CITY:			OCEANSIDE
		STATE:			CA
		ZIP:			92056

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			International Stem Cell CORP
		CENTRAL INDEX KEY:			0001355790
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				204494098
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		2595 JASON COURT
		CITY:			OCEANSIDE
		STATE:			CA
		ZIP:			92056
		BUSINESS PHONE:		760-940-6383

	MAIL ADDRESS:	
		STREET 1:		2595 JASON COURT
		CITY:			OCEANSIDE
		STATE:			CA
		ZIP:			92056

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	BTHC III INC.
		DATE OF NAME CHANGE:	20060310
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>edgar.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2010-11-29</periodOfReport>

    <issuer>
        <issuerCik>0001355790</issuerCik>
        <issuerName>International Stem Cell CORP</issuerName>
        <issuerTradingSymbol>ISCO.OB</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001382694</rptOwnerCik>
            <rptOwnerName>Janus Jeffrey</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O INTERNATIONAL STEM CELL CORP.</rptOwnerStreet1>
            <rptOwnerStreet2>2595 JASON COURT</rptOwnerStreet2>
            <rptOwnerCity>OCEANSIDE,</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>92056</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Senior Vice President</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2010-11-29</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>25000</value>
                    <footnoteId id="F1"/>
                </transactionShares>
                <transactionPricePerShare>
                    <value>1.566</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>2010837</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>Through Family Trust dated 9/17/2008</value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2010-11-30</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>35820</value>
                    <footnoteId id="F1"/>
                </transactionShares>
                <transactionPricePerShare>
                    <value>1.5691</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>1975017</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>Through Family Trust dated 9/17/2008</value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">Sold pursuant to a 10b5-1 sales plan adopted on October 19, 2010.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ Ray Wood as Attorney-in-fact for Jeffrey Janus</signatureName>
        <signatureDate>2010-12-01</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----