SEC Form 4

FORM 4		UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940	OMB APPROVAL OMB Number: 3235-0287 Estimated average burden hours per response: 0.5
	Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

1. Name and Address of Reporting Person* 7-MED Health Ventures LP (Last) (First) (Middle) 16B SHENKAR STREET, P.O.B. 12327 (Street) HERZLIYA PITUACH L3 46733 (City) (State) (Zip)	2. Issuer Name and Ticker or Trading Symbol CHIASMA, INC [ CHMA ]	5. Relationship of Reporting Person(s) to Issuer (Check all applicable) Director X 10% Owner Officer (give title below) Other (specify below)
	3. Date of Earliest Transaction (Month/Day/Year) 07/21/2015
	4. If Amendment, Date of Original Filed (Month/Day/Year)	6. Individual or Joint/Group Filing (Check Applicable Line) Form filed by One Reporting Person X Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	07/21/2015		C		12,337	A	(1)	12,337	D
Common Stock	07/21/2015		C		760,656	A	(1)	772,993	D
Common Stock	07/21/2015		C		514,674	A	(1)	1,287,667	D
Common Stock	07/21/2015		C		328,515	A	(1)	1,616,182	D
Common Stock	07/21/2015		C		273,762	A	(1)	273,762	I	Directly owned by Ruth Wertheimer(2)(3)
Common Stock	07/21/2015		P(4)		93,750	A	$16	93,750	I	Directly owned by Ruth Wertheimer(2)(3)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Series B1' Convertible Preferred Stock	(1)	07/21/2015		C		112,665		(5)	(5)	Common Stock	12,337	(1)	0	D
Series C' Convertible Preferred Stock	(1)	07/21/2015		C		6,946,314		(5)	(5)	Common Stock	760,656	(1)	0	D
Series D' Convertible Preferred Stock	(1)	07/21/2015		C		4,700,000		(5)	(5)	Common Stock	514,674	(1)	0	D
Series E Convertible Preferred Stock	(1)	07/21/2015		C		3,000,000		(5)	(5)	Common Stock	328,515	(1)	0	D
Series E Convertible Preferred Stock	(1)	07/21/2015		C		2,500,000		(5)	(5)	Common Stock	273,762	(1)	0	I	Directly owned by Ruth Wertheimer(2)(3)

1. Name and Address of Reporting Person* 7-MED Health Ventures LP (Last) (First) (Middle) 16B SHENKAR STREET, P.O.B. 12327 (Street) HERZLIYA PITUACH L3 46733 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* Wertheimer Ruth (Last) (First) (Middle) 16B SHENKAR STREET, P.O.B. 12327 (Street) HERZLIYA PITUACH L3 46733 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

Explanation of Responses:

1. Each outstanding share of the Issuer's Series B-1' Preferred Stock, Series C' Preferred Stock, Series D' Preferred Stock and Series E Preferred Stock converted into 0.109505 of a share of the Issuer's Common Stock immediately prior to the closing of the Issuer's initial public offering without payment of consideration. The converted shares had no expiration date.

2. Besides the shares of Common Stock and warrants to purchase shares of Common Stock held directly by Ruth Wertheimer, she also owns (i) an indirect, 80.5% limited partnership interest in 7 Med Health Ventures LP, as well as (ii) 100% of the outstanding equity interests of the general partner of 7 Med Health Ventures LP. She may therefore be deemed to have an indirect pecuniary interest in the shares of Common Stock and Warrants to purchase Common Stock of the Issuer held by 7 Med Health Ventures LP.

3. Ruth Wertheimer disclaims beneficial ownership of securities held by 7 Med Health Ventures LP except to the extent of her pecuniary interest therein.

4. The Reporting Person purchased the shares of Common Stock reported in this row in the Issuer's registered initial public offering in the United States.

5. Each share of the Issuer's Series B1' preferred stock, Series C preferred stock, Series D' preferred stock and Series E preferred stock was automatically converted on a 9.132-for-1 basis into common stock immediately prior to the closing of the Issuer's initial public offering. The shares of Series B1', Series C' and Series D' and Series E preferred stock had no expiration date.

Remarks:

	/s/ Ruth Wertheimer	07/23/2015
	By: 7 Med Health Ventures LP, by 7 Med Ltd., its general partner, by: /s/ Dror Brandwein	07/23/2015
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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