0001306923-19-000015.txt : 20190814 0001306923-19-000015.hdr.sgml : 20190814 20190814161755 ACCESSION NUMBER: 0001306923-19-000015 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20190630 FILED AS OF DATE: 20190814 DATE AS OF CHANGE: 20190814 EFFECTIVENESS DATE: 20190814 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Palo Alto Investors LP CENTRAL INDEX KEY: 0001306923 IRS NUMBER: 770558164 STATE OF INCORPORATION: CA FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-11013 FILM NUMBER: 191026643 BUSINESS ADDRESS: STREET 1: 470 UNIVERSITY AVE CITY: PALO ALTO STATE: CA ZIP: 94301 BUSINESS PHONE: 650-325-0772 MAIL ADDRESS: STREET 1: 470 UNIVERSITY AVE CITY: PALO ALTO STATE: CA ZIP: 94301 FORMER COMPANY: FORMER CONFORMED NAME: Palo Alto Investors, LLC DATE OF NAME CHANGE: 20041025 13F-HR 1 primary_doc.xml 13F-HR LIVE false false false 0001306923 XXXXXXXX 06-30-2019 06-30-2019 false Palo Alto Investors LP

470 University Ave Palo Alto CA 94301

13F HOLDINGS REPORT 028-11013 N Angela Nguyen-Dinh 650-325-0772 /s/ Angela Nguyen-Dinh Palo Alto CA 08-14-2019 0 39 2056939 INFORMATION TABLE 2 infotable.xml ABIOMED INC COM 003654100 183998 706354 SH SOLE 706354 0 0 ACADIA PHARMACEUTICALS INC COM 004225108 61714 2308803 SH SOLE 2308803 0 0 AIMMUNE THERAPEUTICS INC COM 00900T107 79711 3828564 SH SOLE 3828564 0 0 ALDER BIOPHARMACEUTICALS INC COM 014339105 21911 1861630 SH SOLE 1861630 0 0 ALDEYRA THERAPEUTICS INC COM 01438T106 441 73500 SH SOLE 73500 0 0 ALEXION PHARMACEUTICALS INC COM 015351109 134095 1023780 SH SOLE 1023780 0 0 ALIGN TECHNOLOGY INC COM 016255101 40372 147505 SH SOLE 147505 0 0 ALIMERA SCIENCES INC COM 016259103 2682 3013793 SH SOLE 3013793 0 0 AMAG PHARMACEUTICALS INC COM 00163U106 33721 3375506 SH SOLE 3375506 0 0 AMICUS THERAPEUTICS INC COM 03152W109 97298 7796299 SH SOLE 7796299 0 0 BIOMARIN PHARMACEUTICAL INC COM 09061G101 223245 2606485 SH SOLE 2606485 0 0 CELGENE CORP COM 151020104 9880 106883 SH SOLE 106883 0 0 CLOVIS ONCOLOGY INC COM 189464100 76451 5141304 SH SOLE 5141304 0 0 CYTOKINETICS INC COM NEW 23282W605 1391 123686 SH SOLE 123686 0 0 DICERNA PHARMACEUTICALS INC COM 253031108 5226 331813 SH SOLE 331813 0 0 EPIZYME INC COM 29428V104 87035 6935074 SH SOLE 6935074 0 0 EXACT SCIENCES CORP COM 30063P105 37169 314889 SH SOLE 314889 0 0 GILEAD SCIENCES INC COM 375558103 11884 175900 SH SOLE 175900 0 0 HISTOGENICS CORP COM 43358V109 58 302922 SH SOLE 302922 0 0 IDERA PHARMACEUTICALS INC COM PAR 45168K405 206 77044 SH SOLE 77044 0 0 IMMUNOMEDICS INC COM 452907108 92607 6676755 SH SOLE 6676755 0 0 INSMED INC COM PAR $.01 457669307 202007 7890917 SH SOLE 7890917 0 0 KALEIDO BIOSCIENCES INC COM 483347100 10053 866666 SH SOLE 866666 0 0 KARYOPHARM THERAPEUTICS INC COM 48576U106 31521 5262263 SH SOLE 5262263 0 0 MARINUS PHARMACEUTICALS INC COM 56854Q101 520 125321 SH SOLE 125321 0 0 MELINTA THERAPEUTICS INC COM NEW 58549G209 67 10137 SH SOLE 10137 0 0 MINERVA NEUROSCIENCES INC COM 603380106 204 36319 SH SOLE 36319 0 0 MOMENTA PHARMACEUTICALS INC COM 60877T100 23895 1919313 SH SOLE 1919313 0 0 PROTHENA CORP PLC SHS G72800108 11717 1108510 SH SOLE 1108510 0 0 PUMA BIOTECHNOLOGY INC COM 74587V107 17866 1405680 SH SOLE 1405680 0 0 RIGEL PHARMACEUTICALS INC COM NEW 766559603 10403 3985945 SH SOLE 3985945 0 0 SAGE THERAPEUTICS INC COM 78667J108 145562 795031 SH SOLE 795031 0 0 SOPHIRIS BIO INC COM NEW 83578Q209 209 247000 SH SOLE 247000 0 0 STAAR SURGICAL CO COM PAR $0.01 852312305 124485 4237051 SH SOLE 4237051 0 0 SUNESIS PHARMACEUTICALS INC COM PAR 867328700 845 1162473 SH SOLE 1162473 0 0 UNITED THERAPEUTICS CORP DEL COM 91307C102 121211 1552792 SH SOLE 1552792 0 0 VANDA PHARMACEUTICALS INC COM 921659108 71226 5055050 SH SOLE 5055050 0 0 WRIGHT MED GROUP N V ORD SHS N96617118 82643 2771394 SH SOLE 2771394 0 0 ZOGENIX INC COM NEW 98978L204 1410 29500 SH SOLE 29500 0 0