-----BEGIN PRIVACY-ENHANCED MESSAGE----- Proc-Type: 2001,MIC-CLEAR Originator-Name: webmaster@www.sec.gov Originator-Key-Asymmetric: MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB MIC-Info: RSA-MD5,RSA, JoUmBRHsmBs42ZvWKwlURhRMVVwgh7sUkv209+ea2/GpsemQFC51hLxCJdHEDkjb 3vmIgFbv72ADQu+Bq2loQw== 0001140361-11-008216.txt : 20110211 0001140361-11-008216.hdr.sgml : 20110211 20110211152602 ACCESSION NUMBER: 0001140361-11-008216 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 1 CONFORMED PERIOD OF REPORT: 20101231 FILED AS OF DATE: 20110211 DATE AS OF CHANGE: 20110211 EFFECTIVENESS DATE: 20110211 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Palo Alto Investors, LLC CENTRAL INDEX KEY: 0001306923 IRS NUMBER: 770558164 STATE OF INCORPORATION: CA FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-11013 FILM NUMBER: 11598573 BUSINESS ADDRESS: STREET 1: 470 UNIVERSITY AVE CITY: PALO ALTO STATE: CA ZIP: 94301 BUSINESS PHONE: 650-325-0772 MAIL ADDRESS: STREET 1: 470 UNIVERSITY AVE CITY: PALO ALTO STATE: CA ZIP: 94301 13F-HR 1 form13fhr.txt UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 13F Form 13F COVER PAGE Report for the Calendar Year or Quarter Ended: 12/31/2010 Check here if Amendment []; Amendment Number: ------- This Amendment (Check only one.): [] is a restatement. [] adds new holdings entries. Institutional Investment Manager Filing this Report: Name: Palo Alto Investors, LLC Address: 470 University Avenue Palo Alto, CA 94301 Form 13F File Number: 28-10266 The institutional investment manager filing this report and the person by whom it is signed hereby represent that the person signing the report is authorized to submit it, that all information contained herein is true, correct and complete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered integral parts of this form. Persons Signing this Report on Behalf of Reporting Manager: Name: Mark Shamia Title: Chief Operating Officer Phone: (650) 325-0772 Signature, Place, and Date of Signing: /s/ Mark Shamia Palo Alto, CA 2/9/2011 - --------------------------------- --------------------------------- ---------- [Signature] [City, State] [Date] Report Type (Check only one): [X] 13F HOLDINGS REPORT. (Check here if all holdings of this reporting manager are reported in this report.) [ ] 13F NOTICE. (Check here if no holdings reported are in this report, and all holdings are reported by other reporting manager(s).) [ ] 13F COMBINATION REPORT. (Check here if a portion of the holdings for this reporting manager are reported in this report and a portion are reported by other reporting manager(s).) List of Other Managers Reporting for this Manager: Form 13F SUMMARY PAGE Report Summary: Number of Other Included Managers: 0 Form 13F Information Table Entry Total: 50 Form 13F Information Table Value Total: $ 974,079 -------------- (In Thousands) List of Other Included Managers: Provide a numbered list of the name(s) and 13F file number(s) of all institutional investment managers with respect to which this report is filed, other than the manager filing this report. NONE
FORM 13F INFORMATION TABLE COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8 - ----------------------------------- -------------- --------- -------- ------------------- ---------- -------- ---------------------- VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGERS SOLE SHARED NONE - ----------------------------------- -------------- --------- -------- ---------- --- ---- ---------- -------- ---------- ------ ---- Abiomed Inc. csus 003654100 9,035 940,210 940,210 0 0 Aegerion Pharmaceuticals Inc. csus 00767E102 2,521 177,900 177,900 0 0 Alimera Sciences, Inc. csus 016259103 10,442 1,006,013 1,006,013 0 0 AMAG Pharmaceuticals, Inc. csus 00163u106 56,958 3,146,877 3,146,877 0 0 Amicus Therapeutics, Inc. csus 03152W109 30,115 6,407,487 6,407,487 0 0 ArthroCare Corp. csus 043136100 31,445 1,012,408 1,012,408 0 0 Auxilium Pharmaceuticals, Inc. csus 05334D107 44,332 2,101,046 2,101,046 0 0 Biomarin Pharmaceuticals, Inc csus 09061G101 31,321 1,163,053 1,163,053 0 0 BroadVision, Inc. csus 111412706 9,237 738,945 738,945 0 0 Celgene Corp. csus 151020104 5,731 96,903 96,903 0 0 Ceragon Networks Ltd. csus M22013102 26,627 2,020,241 2,020,241 0 0 Contango Oil & Gas Company csus 21075n204 15,062 260,000 260,000 0 0 Cubist Pharmaceuticals, Inc. csus 229678107 21,663 1,012,271 1,012,271 0 0 Cyberonics, Inc. csus 23251P102 103,529 3,337,506 3,337,506 0 0 Cytokinetics Inc. csus 23282W100 1,321 632,031 632,031 0 0 Energy Recovery Inc. csus 29270J100 2,896 791,300 791,300 0 0 EnerNoc, Inc. csus 292764107 7,651 320,000 320,000 0 0 Evergreen Solar, Inc. 4% Due cnus 30033RAC2 13,079 32,294,000 32,294,000 0 0 7/15/2013 First Solar Inc. csus 336433107 1,952 15,000 15,000 0 0 Genoptix Inc. csus 37243V100 5,926 311,570 311,570 0 0 Genzyme Corporation csus 372917104 10,174 142,889 142,889 0 0 Gilead Sciences csus 375558103 3,945 108,845 108,845 0 0 Guaranty Bancorp csus 40075t102 1,134 798,900 798,900 0 0 interCLICK, Inc. csus 458483203 8,258 1,537,772 1,537,772 0 0 Intermune Inc. csus 45884X103 22,653 622,345 622,345 0 0 Medicis Pharmaceutical Corp. csus 584690309 31,561 1,178,100 1,178,100 0 0 Medivation, Inc. csus 58501n101 9,433 621,806 621,806 0 0 Momenta Pharmaceuticals, Inc. csus 60877T100 49,337 3,295,692 3,295,692 0 0 Northern Oil and Gas Inc. csus 665531109 27,328 1,004,339 1,004,339 0 0 NuVasive Inc. csus 670704105 3,798 148,065 148,065 0 0 NxStage Medical, Inc. csus 67072V103 4,128 165,909 165,909 0 0 Onyx Pharmaceuticals, Inc. csus 683399109 66,739 1,810,110 1,810,110 0 0 Orexigen Therapeutics, Inc. csus 686164104 5,494 679,975 679,975 0 0 Orthovita Inc. csus 68750U102 1,677 834,213 834,213 0 0 Procera Networks Inc csus 74269U104 2,170 3,500,000 3,500,000 0 0 Protalix Biotherapeutics Inc. csus 74365A101 1,358 136,053 136,053 0 0 pSivida Corporation csus 74440J101 3,934 769,845 769,845 0 0 Questcor Pharmaceuticals, Inc. csus 74835Y101 41,709 2,831,599 2,831,599 0 0 Rigel Pharmaceuticals Inc. csus 766559603 560 74,407 74,407 0 0 Riverbed Technology, Inc. csus 768573107 3,517 100,000 100,000 0 0 Savient Pharmaceuticals, Inc. csus 80517Q100 52,953 4,753,452 4,753,452 0 0 Sequenom Inc. csus 817337405 17,811 2,218,000 2,218,000 0 0 Sonde Resources Corp. csus 835426107 8,078 2,214,920 2,214,920 0 0 Spectrum Pharmaceuticals Inc. csus 84763A108 343 50,000 50,000 0 0 STAAR Surgical Company csus 852312305 15,032 2,464,297 2,464,297 0 0 Toreador Resources Corporation csus 891050106 8,348 537,900 537,900 0 0 Triangle Petroleum Corporation csus 89600B102 8,938 1,375,137 1,375,137 0 0 United Therapeutics Corp csus 91307C102 37,248 589,184 589,184 0 0 Vanda Pharmaceutical Inc. csus 921659108 10,760 1,137,468 1,137,468 0 0 ViroPharma Incorporated csus 928241108 84,818 4,897,106 4,897,106 0 0
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