-----BEGIN PRIVACY-ENHANCED MESSAGE----- Proc-Type: 2001,MIC-CLEAR Originator-Name: webmaster@www.sec.gov Originator-Key-Asymmetric: MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB MIC-Info: RSA-MD5,RSA, Ogzi+/XxJ6BpivBAjA2iMDhM9NPATHnIa+tBHA4wF0MEeChPsubj7RlR2/UZRJC3 Y1I+f8cVcf6fJEZFxmISyQ== 0001140361-08-012394.txt : 20080514 0001140361-08-012394.hdr.sgml : 20080514 20080514154722 ACCESSION NUMBER: 0001140361-08-012394 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 1 CONFORMED PERIOD OF REPORT: 20080331 FILED AS OF DATE: 20080514 DATE AS OF CHANGE: 20080514 EFFECTIVENESS DATE: 20080514 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Palo Alto Investors, LLC CENTRAL INDEX KEY: 0001306923 IRS NUMBER: 770558164 STATE OF INCORPORATION: CA FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-11013 FILM NUMBER: 08831689 BUSINESS ADDRESS: STREET 1: 470 UNIVERSITY AVE CITY: PALO ALTO STATE: CA ZIP: 94301 BUSINESS PHONE: 650-325-0772 MAIL ADDRESS: STREET 1: 470 UNIVERSITY AVE CITY: PALO ALTO STATE: CA ZIP: 94301 13F-HR 1 form13f.txt PALO ALTO INVESTORS 13F 3-31-2008 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 13F Form 13F COVER PAGE Report for the Calendar Year or Quarter Ended: March 31, 2008 Check here if Amendment [ ]; Amendment Number: ------- This Amendment (Check only one.): [ ] is a restatement. [ ] adds new holdings entries. Institutional Investment Manager Filing this Report: Name: Palo Alto Investors, LLC ----------------------------------------------------- Address: 470 University Avenue Palo Alto, CA 94301 ----------------------------------------------------- Form 13F File Number: 28-10266 -------- The institutional investment manager filing this report and the person by whom it is signed hereby represent that the person signing the report is authorized to submit it, that all information contained herein is true, correct and complete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered integral parts of this form. Person Signing this Report on Behalf of Reporting Manager: Name: /s/ William L. Edwards ------------------------- Title: President of Palo Investors, Manager ------------------------- Phone: (650) 325-0772 ------------------------- Signature, Place, and Date of Signing: /s/ William L. Edwards Palo Alto, CA 5/14/2008 - ---------------------- ------------- ---------- [Signature] [City, State] [Date] Report Type (Check only one): [X] 13F HOLDINGS REPORT. (Check here if all holdings of this reporting manager are reported in this report.) [ ] 13F NOTICE. (Check here if no holdings reported are in this report, and all holdings are reported by other reporting manager(s).) [ ] 13F COMBINATION REPORT. (Check here if a portion of the holdings for this reporting manager are reported in this report and a portion are reported by other reporting manager(s).) List of Other Managers Reporting for this Manager: [If there are no entries in this list, omit this section.] 13F File Number Name 28-____________ ________________________________________ [Repeat as necessary.] Form 13F SUMMARY PAGE Report Summary: Number of Other Included Managers: 0 ----------- Form 13F Information Table Entry Total: 80 ----------- Form 13F Information Table Value Total: $1,335,053 ----------- (thousands) List of Other Included Managers: Provide a numbered list of the name(s) and 13F file number(s) of all institutional investment managers with respect to which this report is filed, other than the manager filing this report. [If there are no entries in this list, state "NONE" and omit the column headings and list entries.] NONE
FORM 13F INFORMATION TABLE VALUE SHARES/ SH/ PUT/ INVSTMT OTHER VOTING AUTHORITY NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DSCRETN MANAGERS SOLE SHARED NONE - ------------------------------ ---------------- --------- -------- -------- --- ---- ------- -------- -------- ------ ---- Aeterna Zentaris COM 007975204 407 395000 SH SOLE 395000 0 0 Akamai Technologies, Inc. COM 00971T101 8987 319124 SH SOLE 319124 0 0 Align Technology, Inc. COM 016255101 13934 1254190 SH SOLE 1254190 0 0 Allis-Chalmers Energy Inc. COM 019645506 57580 4175517 SH SOLE 4175517 0 0 Altus Pharmaceuticals Inc COM 02216N105 384 84290 SH SOLE 84290 0 0 AMAG Pharmaceuticals, Inc. COM 00163u106 54102 1338177 SH SOLE 1338177 0 0 Amazon.com, Inc. COM 023135106 599 8400 SH SOLE 8400 0 0 Amicus Therapeutics, Inc. COM 03152W109 19516 1823942 SH SOLE 1823942 0 0 Anika Therapeutics, Inc. COM 035255108 236 27815 SH SOLE 27815 0 0 Apple Inc. COM 037833100 674 4700 SH SOLE 4700 0 0 Arbios Systems Inc. COM 03875v107 138 461539 SH SOLE 461539 0 0 Auxilium Pharmaceuticals, Inc. COM 05334D107 79416 2969931 SH SOLE 2969931 0 0 Biomarin Pharmaceuticals, Inc COM 09061G101 519 14685 SH SOLE 14685 0 0 Biomimetic Therapeutics, Inc. COM 09064X101 8323 1040316 SH SOLE 1040316 0 0 Bioscrip Inc. COM 09069N108 768 113570 SH SOLE 113570 0 0 BroadVision, Inc. COM 111412607 17539 15384659 SH SOLE 15384659 0 0 Cache, Inc COM 127150308 16287 1442600 SH SOLE 1442600 0 0 Cadence Pharmaceuticals, Inc. COM 12738T100 555 93355 SH SOLE 93355 0 0 CalFrac Well Services Ltd. COM 129584108 9372 430000 SH SOLE 430000 0 0 Canadian Superior Energy Inc. COM 136644101 33375 10801000 SH SOLE 10801000 0 0 Centennial Bank Holdings, Inc. COM 151345303 9890 1574900 SH SOLE 1574900 0 0 Ceragon Networks Ltd. COM M22013102 12498 1322500 SH SOLE 1322500 0 0 Cisco Systems, Inc. COM 17275R102 16282 675900 SH SOLE 675900 0 0 CollaGenex Pharmaceutical, COM 19419B100 1306 78810 SH SOLE 78810 0 0 Inc. Cyberonics, Inc. COM 23251P102 39107 2697032 SH SOLE 2697032 0 0 Cypress Bioscience Inc. COM 232674507 3882 542164 SH SOLE 542164 0 0 Digital River, Inc. COM 25388B104 14887 480700 SH SOLE 480700 0 0 Ember Resources Inc. COM 29081X108 3214 2337500 SH SOLE 2337500 0 0 ev3 Inc COM 26928A200 20741 2548040 SH SOLE 2548040 0 0 Evergreen Solar, Inc. COM 30033R108 11124 1200000 SH SOLE 1200000 0 0 F5 Networks, Inc. COM 315616102 2115 116400 SH SOLE 116400 0 0 Frontier Oil Corporation COM 35914P105 16356 600000 SH SOLE 600000 0 0 Gastar Exploration Limited COM 367299104 33109 25468100 SH SOLE 25468100 0 0 Genomic Health, Inc. COM 37244C101 2033 107620 SH SOLE 107620 0 0 Genzyme Corporation COM 372917104 24784 332498 SH SOLE 332498 0 0 Gigamedia Limited COM Y2711Y104 16057 1029941 SH SOLE 1029941 0 0 Helmerich Payne, Inc. COM 423452101 17337 369900 SH SOLE 369900 0 0 IDM Pharma Inc. COM 449394105 16957 7372409 SH SOLE 7372409 0 0 ImClone Systems Incorporated COM 45245W109 36538 861345 SH SOLE 861345 0 0 Limelight Networks, Inc. COM 53261M104 18415 5683673 SH SOLE 5683673 0 0 Martek Biosciences Corp COM 572901106 550 18000 SH SOLE 18000 0 0 Medicis Pharmaceutical Corp. COM 584690309 12924 656350 SH SOLE 656350 0 0 Medivation, Inc. COM 58501n101 28742 2019829 SH SOLE 2019829 0 0 Merck & Co., Inc COM 589331107 388 10225 SH SOLE 10225 0 0 Momenta Pharmaceuticals, Inc. COM 60877T100 14511 1327658 SH SOLE 1327658 0 0 NuVasive Inc. COM 670704105 4321 125215 SH SOLE 125215 0 0 NVIDIA Corporation COM 67066g104 1930 97500 SH SOLE 97500 0 0 NxStage Medical, Inc. COM 67072V103 6010 1391310 SH SOLE 1391310 0 0 Oceaneering International COM 675232102 17829 283000 SH SOLE 283000 0 0 Oilexco Incorporated COM 667909103 2619 200000 SH SOLE 200000 0 0 Onyx Pharmaceuticals, Inc. COM 683399109 68879 2372670 SH SOLE 2372670 0 0 Oplink Communications COM 68375Q403 2133 240500 SH SOLE 240500 0 0 Peets Coffee & Tea, Inc COM 705560100 39527 1681275 SH SOLE 1681275 0 0 Petroquest Energy Inc. COM 716748108 14704 848000 SH SOLE 848000 0 0 Photomedex Inc COM 719358103 1832 1991330 SH SOLE 1991330 0 0 Plains Exploration & COM 726505100 33478 630000 SH SOLE 630000 0 0 Production Company Portfolio Recovery Associates, COM 73640Q105 25384 591845 SH SOLE 591845 0 0 Inc. Questcor Pharmaceuticals COM 74835Y101 6687 1622987 SH SOLE 1622987 0 0 Restoration Hardware, Inc. COM 760981100 19465 4474800 SH SOLE 4474800 0 0 Savient Pharmaceuticals, Inc. COM 80517Q100 132166 6608298 SH SOLE 6608298 0 0 Spreadtrum Communications COM 849415203 1977 227200 SH SOLE 227200 0 0 St. Jude Medical, Inc. COM 790849103 15331 354960 SH SOLE 354960 0 0 Sun Microsystems, Inc. COM 866810203 15698 1010825 SH SOLE 1010825 0 0 Superior Energy Services Inc COM 868157108 12678 320000 SH SOLE 320000 0 0 T-3 Energy Services, Inc. COM 87306e107 14049 330100 SH SOLE 330100 0 0 Tesco Corporation COM 88157K101 5748 240000 SH SOLE 240000 0 0 The9 Limited COM 88337K104 26249 1280450 SH SOLE 1280450 0 0 Toreador Resources Corporation COM 891050106 14199 1825000 SH SOLE 1825000 0 0 Transocean Inc. COM G90073100 16705 123554 SH SOLE 123554 0 0 Triangle Petroleum Corporation COM 89600B102 6740 7247000 SH SOLE 7247000 0 0 Unica Corporation COM 904583101 12657 1861394 SH SOLE 1861394 0 0 United Therapeutics Corp COM 91307C102 9674 111575 SH SOLE 111575 0 0 UTS Energy Corporation (UEYCF) COM 903396109 18589 3644600 SH SOLE 3644600 0 0 Vanda Pharma COM 921659108 2091 540190 SH SOLE 540190 0 0 Verasun Energy Corporation COM 92336G106 13455 1830600 SH SOLE 1830600 0 0 ViroPharma Incorporated COM 928241108 8764 980311 SH SOLE 980311 0 0 WebSense Inc. COM 947684106 29396 1567787 SH SOLE 1567787 0 0 Western Alliance Bancorp COM 957638109 6245 485600 SH SOLE 485600 0 0 Whole Foods Market, Inc. COM 966837106 14378 436100 SH SOLE 436100 0 0 Xtreme Coil Drilling Corp. COM 98417d102 17008 2325300 SH SOLE 2325300 0 0 (XDC.CN)
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