Chief Compliance Officer

0001104659-20-094384.txt : 20200813 0001104659-20-094384.hdr.sgml : 20200813 20200813083933 ACCESSION NUMBER: 0001104659-20-094384 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20200630 FILED AS OF DATE: 20200813 DATE AS OF CHANGE: 20200813 EFFECTIVENESS DATE: 20200813 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Tekla Capital Management LLC CENTRAL INDEX KEY: 0001300336 IRS NUMBER: 010628853 STATE OF INCORPORATION: DE FISCAL YEAR END: 0930 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-10950 FILM NUMBER: 201097378 BUSINESS ADDRESS: STREET 1: 100 FEDERAL STREET STREET 2: 19TH FLOOR CITY: BOSTON STATE: MA ZIP: 02110 BUSINESS PHONE: 617 772-8500 MAIL ADDRESS: STREET 1: 100 FEDERAL STREET STREET 2: 19TH FLOOR CITY: BOSTON STATE: MA ZIP: 02110 FORMER COMPANY: FORMER CONFORMED NAME: Hambrecht & Quist Capital Management LLC DATE OF NAME CHANGE: 20040811 13F-HR 1 primary_doc.xml 13F-HR LIVE 0001300336 XXXXXXXX 06-30-2020 06-30-2020 false Tekla Capital Management LLC

100 FEDERAL STREET 19TH FLOOR BOSTON MA 02110

13F HOLDINGS REPORT 028-10950 N Laura Woodward Chief Compliance Officer 617-772-8500 /s/ Laura Woodward Boston MA 08-13-2020 0 222 2627390 false INFORMATION TABLE 2 a20-22392_1informationtable.xml INFORMATION TABLE Abbott Laboratories Common 002824100 44458 486250 SH SOLE 486250 0 0 AbbVie Inc. Common 00287Y109 52401 533725 SH SOLE 533725 0 0 ABIOMED, Inc. Common 003654100 3815 15794 SH SOLE 15794 0 0 AC Immune SA Shares H00263105 1156 171813 SH SOLE 171813 0 0 Acadia Healthcare Company, Inc. Common 00404A109 3296 131200 SH SOLE 131200 0 0 ACADIA Pharmaceuticals Inc. Common 004225108 12154 250743 SH SOLE 250743 0 0 Acceleron Pharma Inc. Common 00434H108 3869 40606 SH SOLE 40606 0 0 Addus HomeCare Corp. Common 006739106 1478 15969 SH SOLE 15969 0 0 Aerie Pharmaceuticals, Inc. Common 00771V108 984 66688 SH SOLE 66688 0 0 Aerpio Pharmaceuticals, Inc. Common 00810B105 322 257554 SH SOLE 257554 0 0 Agilent Technologies, Inc. Common 00846U101 4642 52525 SH SOLE 52525 0 0 Agios Pharmaceuticals, Inc. Common 00847X104 9999 186964 SH SOLE 186964 0 0 Alcon Inc. Ordinary Shares H01301128 2103 36686 SH SOLE 36686 0 0 Alexion Pharmaceuticals, Inc. Common 015351109 43180 384709 SH SOLE 384709 0 0 Align Technology, Inc. Common 016255101 2756 10041 SH SOLE 10041 0 0 Alkermes plc Shares G01767105 3297 169930 SH SOLE 169930 0 0 Allakos Inc. Common 01671P100 4628 64397 SH SOLE 64397 0 0 Allogene Therapeutics, Inc. Common 019770106 9252 216069 SH SOLE 216069 0 0 Alnylam Pharmaceuticals, Inc. Common 02043Q107 18642 125867 SH SOLE 125867 0 0 Amarin Corporation plc Sponsored ADR 023111206 5879 849588 SH SOLE 849588 0 0 Amedisys, Inc. Common 023436108 3851 19395 SH SOLE 19395 0 0 AmerisourceBergen Corp. Common 03073E105 8127 80645 SH SOLE 80645 0 0 Amgen Inc. Common 031162100 144337 611962 SH SOLE 611962 0 0 Amicus Therapeutics, Inc. Common 03152W109 5082 336984 SH SOLE 336984 0 0 AnaptysBio, Inc. Common 032724106 2642 118261 SH SOLE 118261 0 0 Anthem, Inc. Common 036752103 10583 40242 SH SOLE 40242 0 0 Apellis Pharmaceuticals, Inc. Common 03753U106 5666 173494 SH SOLE 173494 0 0 ARCA biopharma, Inc. Common 00211Y506 215 32461 SH SOLE 32461 0 0 Ardelyx, Inc. Common 039697107 4205 607698 SH SOLE 607698 0 0 Arena Pharmaceuticals, Inc. Common 040047607 5540 88002 SH SOLE 88002 0 0 argenx SE Sponsored ADR 04016X101 10130 44977 SH SOLE 44977 0 0 Arrowhead Pharmaceuticals, Inc. Common 04280A100 3204 74186 SH SOLE 74186 0 0 Ascendis Pharma A/S Sponsored ADR 04351P101 8502 57482 SH SOLE 57482 0 0 Assertio Holdings, Inc. Common 04546C106 1407 1642302 SH SOLE 1642302 0 0 AstraZeneca PLC Sponsored ADR 046353108 12418 234798 SH SOLE 234798 0 0 Atreca, Inc. Class A Common 04965G109 7500 352424 SH SOLE 352424 0 0 Aurinia Pharmaceuticals Inc. Common 05156V102 1475 90788 SH SOLE 90788 0 0 Avadel Pharmaceuticals plc Sponsored ADR 05337M104 1888 233612 SH SOLE 233612 0 0 AVROBIO, Inc. Common 05455M100 2453 140581 SH SOLE 140581 0 0 Axonics Modulation Technologies, Inc. Common 05465P101 987 28100 SH SOLE 28100 0 0 Axsome Therapeutics, Inc. Common 05464T104 2599 31591 SH SOLE 31591 0 0 Bausch Health Companies Inc. Common 071734107 2166 118412 SH SOLE 118412 0 0 Baxter International Inc. Common 071813109 10506 122023 SH SOLE 122023 0 0 Becton, Dickinson and Co. Common 075887109 18604 77754 SH SOLE 77754 0 0 BeiGene, Ltd. Sponsored ADR 07725L102 14127 74984 SH SOLE 74984 0 0 Bellicum Pharmaceuticals, Inc. Common 079481404 45 6000 SH SOLE 6000 0 0 Bio-Techne Corp. Common 09073M104 13655 51710 SH SOLE 51710 0 0 Biogen Inc. Common 09062X103 62499 233599 SH SOLE 233599 0 0 Biohaven Pharmaceutical Holding Company Ltd. Common G11196105 2506 34277 SH SOLE 34277 0 0 BioMarin Pharmaceutical Inc. Common 09061G101 30263 245362 SH SOLE 245362 0 0 bluebird bio, Inc. Common 09609G100 5139 84194 SH SOLE 84194 0 0 Blueprint Medicines Corp. Common 09627Y109 9224 118256 SH SOLE 118256 0 0 Boston Scientific Corp. Common 101137107 22644 644935 SH SOLE 644935 0 0 BridgeBio Pharma, Inc. Common 10806X102 1279 39228 SH SOLE 39228 0 0 Bristol-Myers Squibb Co. Common 110122108 57477 977505 SH SOLE 977505 0 0 Bristol-Myers Squibb Co. Right 110122157 5276 1473710 SH SOLE 1473710 0 0 Celldex Therapeutics, Inc. Common 15117B202 92 7053 SH SOLE 7053 0 0 Cellectis Sponsored ADR 15117K103 1961 110147 SH SOLE 110147 0 0 Centene Corp. Common 15135B101 18315 288194 SH SOLE 288194 0 0 Cerner Corp. Common 156782104 5587 81500 SH SOLE 81500 0 0 Charles River Laboratories International, Inc. Common 159864107 3220 18467 SH SOLE 18467 0 0 Cidara Therapeutics, Inc. Common 171757107 720 195256 SH SOLE 195256 0 0 Cigna Corp. Common 125523100 15010 79988 SH SOLE 79988 0 0 Clearside Biomedical, Inc. Common 185063104 311 165330 SH SOLE 165330 0 0 Coherus Biosciences, Inc. Common 19249H103 3627 203103 SH SOLE 203103 0 0 Community Health Systems, Inc. Common 203668108 354 117735 SH SOLE 117735 0 0 Community Healthcare Trust Inc. Common 20369C106 609 14900 SH SOLE 14900 0 0 Corbus Pharmaceuticals Holdings, Inc. Common 21833P103 3177 378706 SH SOLE 378706 0 0 CRISPR Therapeutics AG Namen AKT H17182108 5602 76222 SH SOLE 76222 0 0 CVS Health Corp. Common 126650100 46754 719620 SH SOLE 719620 0 0 CymaBay Therapeutics, Inc. Common 23257D103 307 88102 SH SOLE 88102 0 0 Danaher Corp. Common 235851102 28178 159352 SH SOLE 159352 0 0 Deciphera Pharmaceuticals, Inc. Common 24344T101 3665 61370 SH SOLE 61370 0 0 DENTSPLY SIRONA Inc. Common 24906P109 7106 161287 SH SOLE 161287 0 0 DexCom, Inc. Common 252131107 2940 7251 SH SOLE 7251 0 0 Diversified Healthcare Trust Common 25525P107 1583 357720 SH SOLE 357720 0 0 Editas Medicine, Inc. Common 28106W103 3851 130201 SH SOLE 130201 0 0 Edwards Lifesciences Corp. Common 28176E108 13970 202146 SH SOLE 202146 0 0 Eidos Therapeutics, Inc. Common 28249H104 953 20000 SH SOLE 20000 0 0 Eli Lilly and Co. Common 532457108 33958 206837 SH SOLE 206837 0 0 Endo International plc Shares G30401106 1823 531570 SH SOLE 531570 0 0 Epizyme, Inc. Common 29428V104 3336 207752 SH SOLE 207752 0 0 Esperion Therapeutics, Inc. Common 29664W105 2133 41577 SH SOLE 41577 0 0 Evolent Health, Inc. Common 30050B101 1645 231027 SH SOLE 231027 0 0 Exact Sciences Corp. Common 30063P105 3827 44015 SH SOLE 44015 0 0 Exelixis, Inc. Common 30161Q104 22172 933949 SH SOLE 933949 0 0 Fate Therapeutics, Inc. Common 31189P102 6370 185672 SH SOLE 185672 0 0 FibroGen, Inc. Common 31572Q808 7874 194270 SH SOLE 194270 0 0 Five Star Senior Living Inc. Common 33832D205 95 24237 SH SOLE 24237 0 0 Galapagos NV Sponsored ADR 36315X101 1291 6543 SH SOLE 6543 0 0 Galera Therapeutics, Inc. Common 36338D108 7439 1041845 SH SOLE 1041845 0 0 Genmab A/S Sponsored ADS 372303206 560 16520 SH SOLE 16520 0 0 Gilead Sciences, Inc. Common 375558103 121644 1581026 SH SOLE 1581026 0 0 GlaxoSmithKline PLC Shares 37733W105 8985 220263 SH SOLE 220263 0 0 Global Blood Therapeutics, Inc. Common 37890U108 4530 71759 SH SOLE 71759 0 0 Global Medical REIT Inc. Common 37954A204 1982 174897 SH SOLE 174897 0 0 Grifols, S.A. Sponsored ADR 398438408 864 47373 SH SOLE 47373 0 0 Guardant Health, Inc. Common 40131M109 6606 81422 SH SOLE 81422 0 0 GW Pharmaceuticals plc ADS 36197T103 3074 25051 SH SOLE 25051 0 0 Halozyme Therapeutics, Inc. Common 40637H109 1874 69917 SH SOLE 69917 0 0 HCA Healthcare, Inc. Common 40412C101 8137 83833 SH SOLE 83833 0 0 Health Care Select Sector SPDR Fund SBI Healthcare 81369Y209 1006 10055 SH SOLE 10055 0 0 Healthcare Realty Trust Inc. Common 421946104 3047 104024 SH SOLE 104024 0 0 Healthcare Trust of America, Inc. Common 42225P501 1874 70662 SH SOLE 70662 0 0 Healthpeak Properties, Inc. Common 42250P103 4145 150392 SH SOLE 150392 0 0 Heron Therapeutics, Inc. Common 427746102 1930 131183 SH SOLE 131183 0 0 Hologic, Inc. Common 436440101 1856 32564 SH SOLE 32564 0 0 Horizon Therapeutics plc Shares G46188101 22796 410153 SH SOLE 410153 0 0 Humana Inc. Common 444859102 18808 48506 SH SOLE 48506 0 0 IDEXX Laboratories, Inc. Common 45168D104 12221 37014 SH SOLE 37014 0 0 Illumina, Inc. Common 452327109 79496 214651 SH SOLE 214651 0 0 ImmunoGen, Inc. Common 45253H101 774 168190 SH SOLE 168190 0 0 Immunomedics, Inc. Common 452907108 17617 497103 SH SOLE 497103 0 0 Incyte Corp. Common 45337C102 33796 325053 SH SOLE 325053 0 0 Innate Pharma SA Sponsored ADS B1G5FB909 858 137734 SH SOLE 137734 0 0 Inogen, Inc. Common 45780L104 1826 51406 SH SOLE 51406 0 0 Inovio Pharmaceuticals, Inc. Common 45773H201 5445 202038 SH SOLE 202038 0 0 Insmed Inc. Common 457669307 2710 98387 SH SOLE 98387 0 0 Intellia Therapeutics, Inc. Common 45826J105 1157 55050 SH SOLE 55050 0 0 Intercept Pharmaceuticals, Inc. Common 45845P108 3692 77067 SH SOLE 77067 0 0 Intra-Cellular Therapies, Inc. Common 46116X101 2419 94238 SH SOLE 94238 0 0 Intuitive Surgical, Inc. Common 46120E602 18998 33339 SH SOLE 33339 0 0 Ionis Pharmaceuticals, Inc. Common 462222100 11391 193201 SH SOLE 193201 0 0 Iovance Biotherapeutics, Inc. Common 462260100 7441 271073 SH SOLE 271073 0 0 IQVIA Holdings Inc. Common 46266C105 11672 82266 SH SOLE 82266 0 0 Jazz Pharmaceuticals plc Shares G50871105 7443 67456 SH SOLE 67456 0 0 Johnson & Johnson Common 478160104 116727 830031 SH SOLE 830031 0 0 Karuna Therapeutics, Inc. Common 48576A100 3330 29873 SH SOLE 29873 0 0 Kodiak Sciences Inc. Common 50015M109 1253 23153 SH SOLE 23153 0 0 Koninklijke Philips N.V. NY Reg Sh 500472303 2613 55796 SH SOLE 55796 0 0 Laboratory Corporation of America Holdings Sponsored ADR 50540R409 7849 47251 SH SOLE 47251 0 0 Ligand Pharmaceuticals Inc. Common 53220K504 3421 30590 SH SOLE 30590 0 0 LTC Properties, Inc. Common 502175102 6867 182293 SH SOLE 182293 0 0 Madrigal Pharmaceuticals, Inc. Common 558868105 1511 13340 SH SOLE 13340 0 0 Magenta Therapeutics, Inc. Common 55910K108 1445 192431 SH SOLE 192431 0 0 Mallinckrodt plc Sponsored ADR G5785G107 88 32980 SH SOLE 32980 0 0 McKesson Corp. Common 58155Q103 16498 107537 SH SOLE 107537 0 0 Medical Properties Trust, Inc. Common 58463J304 7741 411743 SH SOLE 411743 0 0 Medpace Holdings, Inc. Common 58506Q109 1755 18871 SH SOLE 18871 0 0 Medtronic plc Shares G5960L103 43602 475489 SH SOLE 475489 0 0 Menlo Therapeutics Inc. Common 586858102 937 541584 SH SOLE 541584 0 0 Merck & Co., Inc. Common 58933Y105 75126 971496 SH SOLE 971496 0 0 Mettler-Toledo International Inc. Common 592688105 4932 6123 SH SOLE 6123 0 0 Milestone Pharmaceuticals Inc. Common 59935V107 806 213310 SH SOLE 213310 0 0 Mirati Therapeutics, Inc. Common 60468T105 8995 78784 SH SOLE 78784 0 0 Moderna, Inc. Common 60770K107 31624 492506 SH SOLE 492506 0 0 Molecular Templates, Inc. Common 608550109 583 42313 SH SOLE 42313 0 0 Molina Healthcare, Inc. Common 60855R100 4901 27536 SH SOLE 27536 0 0 Momenta Pharmaceuticals, Inc. Common 60877T100 3719 111768 SH SOLE 111768 0 0 MorphoSys AG Sponsored ADS 617760202 614 19390 SH SOLE 19390 0 0 Mylan N.V. Shares N59465109 16253 1010754 SH SOLE 1010754 0 0 MyoKardia, Inc. Common 62857M105 1865 19300 SH SOLE 19300 0 0 National Health Investors, Inc. Common 63633D104 610 10038 SH SOLE 10038 0 0 Nektar Therapeutics Common 640268108 6093 263079 SH SOLE 263079 0 0 Neurocrine Biosciences, Inc. Common 64125C109 25150 206150 SH SOLE 206150 0 0 New Senior Investment Group Inc. Common 648691103 928 256398 SH SOLE 256398 0 0 Novartis AG Sponsored ADR 66987V109 14936 171008 SH SOLE 171008 0 0 Novavax, Inc. Common 670002401 2380 28550 SH SOLE 28550 0 0 Novo Nordisk A/S Sponsored ADR 670100205 8775 134005 SH SOLE 134005 0 0 NovoCure Ltd. Ordinary Shares G6674U108 7806 131637 SH SOLE 131637 0 0 Omega Healthcare Investors, Inc. Common 681936100 9110 306433 SH SOLE 306433 0 0 Ovid Therapeutics Inc. Sponsored ADR 690469101 2747 372733 SH SOLE 372733 0 0 Pacific Biosciences of California, Inc. Common 69404D108 1709 495495 SH SOLE 495495 0 0 PerkinElmer, Inc. Common 714046109 3776 38494 SH SOLE 38494 0 0 Perrigo Company plc Shares G97822103 2831 51224 SH SOLE 51224 0 0 Pfizer Inc. Common 717081103 54169 1656548 SH SOLE 1656548 0 0 Physicians Realty Trust Common 71943U104 8685 495733 SH SOLE 495733 0 0 Pieris Pharmaceuticals, Inc. Common 720795103 4493 1449269 SH SOLE 1449269 0 0 Portola Pharmaceuticals, Inc. Sponsored ADR 737010108 1965 109246 SH SOLE 109246 0 0 PRA Health Sciences, Inc. Common 69354M108 13962 143508 SH SOLE 143508 0 0 Principia Biopharma Inc. Common 74257L108 3611 60390 SH SOLE 60390 0 0 PTC Therapeutics, Inc. Common 69366J200 6131 120827 SH SOLE 120827 0 0 Puma Biotechnology, Inc. Common 74587V107 744 71340 SH SOLE 71340 0 0 Quest Diagnostics Inc. Common 74834L100 2396 21025 SH SOLE 21025 0 0 Quotient Ltd. Common G73268107 3048 411937 SH SOLE 411937 0 0 Reata Pharmaceuticals, Inc. Class A 75615P103 7943 50907 SH SOLE 50907 0 0 Regeneron Pharmaceuticals, Inc. Common 75886F107 117206 187935 SH SOLE 187935 0 0 REGENXBIO Inc. Common 75901B107 799 21700 SH SOLE 21700 0 0 ResMed Inc. Common 761152107 3424 17831 SH SOLE 17831 0 0 Revance Therapeutics, Inc. Common 761330109 2096 85840 SH SOLE 85840 0 0 Rocket Pharmaceuticals, Inc. Common 77313F106 6049 289029 SH SOLE 289029 0 0 Rubius Therapeutics, Inc. Common 78116T103 933 155982 SH SOLE 155982 0 0 Sabra Health Care REIT, Inc. Common 78573L106 7369 510660 SH SOLE 510660 0 0 Sage Therapeutics Inc Common 78667J108 4000 96211 SH SOLE 96211 0 0 Sangamo Therapeutics, Inc. Common 800677106 1343 149835 SH SOLE 149835 0 0 Sanofi Sponsored ADR 80105N105 16712 327367 SH SOLE 327367 0 0 Sarepta Therapeutics, Inc. Common 803607100 22468 140129 SH SOLE 140129 0 0 Seattle Genetics, Inc. Common 812578102 40876 240559 SH SOLE 240559 0 0 Smith & Nephew plc Shares 83175M205 3795 99560 SH SOLE 99560 0 0 Spectrum Pharmaceuticals, Inc. Common 84763A108 388 114670 SH SOLE 114670 0 0 STERIS plc Shares G8473T100 1721 11218 SH SOLE 11218 0 0 Stryker Corp. Common 863667101 29593 164230 SH SOLE 164230 0 0 Sutro Biopharma, Inc. Common 869367102 4976 641268 SH SOLE 641268 0 0 Syneos Health, Inc. Class A 87166B102 6291 108001 SH SOLE 108001 0 0 Takeda Pharmaceutical Company Ltd. Sponsored ADS 874060205 3768 210146 SH SOLE 210146 0 0 Teleflex Inc. Common 879369106 6279 17252 SH SOLE 17252 0 0 Tenet Healthcare Corp. Common 88033G407 1752 96736 SH SOLE 96736 0 0 Tetraphase Pharmaceuticals, Inc. Common 88165N204 108 42965 SH SOLE 42965 0 0 Teva Pharmaceutical Industries Ltd. Sponsored ADR 881624209 9690 785851 SH SOLE 785851 0 0 Theravance Biopharma, Inc. Common G8807B106 4803 228836 SH SOLE 228836 0 0 Thermo Fisher Scientific Inc. Common 883556102 38417 106025 SH SOLE 106025 0 0 Tricida, Inc. Common 89610F101 1384 50370 SH SOLE 50370 0 0 Trillium Therapeutics Inc. Common 89620X506 3625 448049 SH SOLE 448049 0 0 Turning Point Therapeutics, Inc. Common 90041T108 367 5677 SH SOLE 5677 0 0 Ultragenyx Pharmaceutical Inc. Common 90400D108 7625 97480 SH SOLE 97480 0 0 uniQure N.V. Shares N90064101 2841 63039 SH SOLE 63039 0 0 United Therapeutics Corp. Class B 91307C102 7685 63513 SH SOLE 63513 0 0 Unitedhealth Group Inc. Common 91324P102 82631 280151 SH SOLE 280151 0 0 Universal Health Realty Income Trust Shares 91359E105 895 11258 SH SOLE 11258 0 0 Ventas, Inc. Common 92276F100 7621 208108 SH SOLE 208108 0 0 Verona Pharma plc Sponsored ADR 925050106 1182 253179 SH SOLE 253179 0 0 Vertex Pharmaceuticals Inc. Common 92532F100 138574 477330 SH SOLE 477330 0 0 Waters Corporation Common 941848103 6708 37184 SH SOLE 37184 0 0 WaVe Life Sciences Ltd. Shares Y95308105 1334 128146 SH SOLE 128146 0 0 Welltower Inc. Common 95040Q104 10510 203083 SH SOLE 203083 0 0 Xencor, Inc. Common 98401F105 4801 148231 SH SOLE 148231 0 0 Y-mAbs Therapeutics, Inc. Common 984241109 3307 76548 SH SOLE 76548 0 0 Zai Lab Ltd. ADR 98887Q104 3082 37523 SH SOLE 37523 0 0 Zimmer Biomet Holdings, Inc. Common 98956P102 11298 94653 SH SOLE 94653 0 0 Zoetis Inc. Class A 98978V103 11117 81121 SH SOLE 81121 0 0 Zogenix, Inc. Common 98978L204 5818 215406 SH SOLE 215406 0 0 Zymeworks Inc. Common 98985W102 2018 55938 SH SOLE 55938 0 0