Chief Compliance Officer

0001104659-20-061314.txt : 20200514 0001104659-20-061314.hdr.sgml : 20200514 20200514111159 ACCESSION NUMBER: 0001104659-20-061314 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20200331 FILED AS OF DATE: 20200514 DATE AS OF CHANGE: 20200514 EFFECTIVENESS DATE: 20200514 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Tekla Capital Management LLC CENTRAL INDEX KEY: 0001300336 IRS NUMBER: 010628853 STATE OF INCORPORATION: DE FISCAL YEAR END: 0930 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-10950 FILM NUMBER: 20876197 BUSINESS ADDRESS: STREET 1: 100 FEDERAL STREET STREET 2: 19TH FLOOR CITY: BOSTON STATE: MA ZIP: 02110 BUSINESS PHONE: 617 772-8500 MAIL ADDRESS: STREET 1: 100 FEDERAL STREET STREET 2: 19TH FLOOR CITY: BOSTON STATE: MA ZIP: 02110 FORMER COMPANY: FORMER CONFORMED NAME: Hambrecht & Quist Capital Management LLC DATE OF NAME CHANGE: 20040811 13F-HR 1 primary_doc.xml 13F-HR LIVE 0001300336 XXXXXXXX 03-31-2020 03-31-2020 false Tekla Capital Management LLC

100 FEDERAL STREET 19TH FLOOR BOSTON MA 02110

13F HOLDINGS REPORT 028-10950 N Laura Woodward Chief Compliance Officer 617-772-8500 /s/ Laura Woodward Boston MA 05-14-2020 0 217 2212059 false INFORMATION TABLE 2 a20-18243_1informationtable.xml INFORMATION TABLE Abbott Laboratories Common 002824100 36815 466550 SH SOLE 466550 0 0 AbbVie Inc. Common 00287Y109 25974 340916 SH SOLE 340916 0 0 ABIOMED, Inc. Common 003654100 4285 29516 SH SOLE 29516 0 0 AC Immune SA Shares H00263105 1187 171813 SH SOLE 171813 0 0 Acadia Healthcare Company, Inc. Common 00404A109 2408 131200 SH SOLE 131200 0 0 ACADIA Pharmaceuticals Inc. Common 004225108 9363 221599 SH SOLE 221599 0 0 Acceleron Pharma Inc. Common 00434H108 3649 40606 SH SOLE 40606 0 0 Aerie Pharmaceuticals, Inc. Common 00771V108 900 66688 SH SOLE 66688 0 0 Aerpio Pharmaceuticals, Inc. Common 00810B105 142 257554 SH SOLE 257554 0 0 Agilent Technologies, Inc. Common 00846U101 3762 52525 SH SOLE 52525 0 0 Agios Pharmaceuticals, Inc. Common 00847X104 6633 186964 SH SOLE 186964 0 0 Alcon Inc. Ordinary Shares H01301128 1864 36686 SH SOLE 36686 0 0 Alexion Pharmaceuticals, Inc. Common 015351109 37113 413326 SH SOLE 413326 0 0 Align Technology, Inc. Common 016255101 1747 10041 SH SOLE 10041 0 0 Alkermes plc Shares G01767105 2450 169930 SH SOLE 169930 0 0 Allakos Inc. Common 01671P100 2865 64397 SH SOLE 64397 0 0 Allergan plc Shares G0177J108 27978 157981 SH SOLE 157981 0 0 Allogene Therapeutics, Inc. Common 019770106 4748 244261 SH SOLE 244261 0 0 Alnylam Pharmaceuticals, Inc. Common 02043Q107 14980 137617 SH SOLE 137617 0 0 Amarin Corporation plc Sponsored ADR 023111206 2415 603791 SH SOLE 603791 0 0 AmerisourceBergen Corporation Common 03073E105 4788 54107 SH SOLE 54107 0 0 Amgen Inc. Common 031162100 121612 599871 SH SOLE 599871 0 0 Amicus Therapeutics, Inc. Common 03152W109 3409 368960 SH SOLE 368960 0 0 AnaptysBio, Inc. Common 032724106 1671 118261 SH SOLE 118261 0 0 Anthem, Inc. Common 036752103 14887 65568 SH SOLE 65568 0 0 Apellis Pharmaceuticals, Inc. Common 03753U106 4648 173494 SH SOLE 173494 0 0 ARCA biopharma, Inc. Common 00211Y506 100 36068 SH SOLE 36068 0 0 Ardelyx, Inc. Common 039697107 3455 607698 SH SOLE 607698 0 0 Arena Pharmaceuticals, Inc. Common 040047607 1176 28002 SH SOLE 28002 0 0 argenx SE Sponsored ADR 04016X101 5925 44977 SH SOLE 44977 0 0 Arrowhead Pharmaceuticals, Inc. Common 04280A100 2134 74186 SH SOLE 74186 0 0 Ascendis Pharma A/S Sponsored ADR 04351P101 7807 69332 SH SOLE 69332 0 0 AstraZeneca PLC Sponsored ADR 046353108 12331 276098 SH SOLE 276098 0 0 Atreca, Inc. Class A Common 04965G109 5833 352424 SH SOLE 352424 0 0 Aurinia Pharmaceuticals Inc. Common 05156V102 1317 90788 SH SOLE 90788 0 0 Avadel Pharmaceuticals plc Sponsored ADR 05337M104 4495 566066 SH SOLE 566066 0 0 AVROBIO, Inc. Common 05455M100 1165 74874 SH SOLE 74874 0 0 Axonics Modulation Technologies, Inc. Common 05465P101 714 28100 SH SOLE 28100 0 0 Axsome Therapeutics, Inc. Common 05464T104 1858 31591 SH SOLE 31591 0 0 Bausch Health Companies Inc. Common 071734107 1835 118412 SH SOLE 118412 0 0 Baxter International Inc. Common 071813109 7890 97183 SH SOLE 97183 0 0 Becton, Dickinson and Company Common 075887109 17866 77754 SH SOLE 77754 0 0 BeiGene, Ltd. Sponsored ADR 07725L102 9231 74984 SH SOLE 74984 0 0 Bellicum Pharmaceuticals, Inc. Common 079481404 28 6000 SH SOLE 6000 0 0 Bio-Techne Corporation Common 09073M104 10939 57691 SH SOLE 57691 0 0 Biogen Inc. Common 09062X103 105271 332735 SH SOLE 332735 0 0 Biohaven Pharmaceutical Holding Company Ltd. Common G11196105 1537 45164 SH SOLE 45164 0 0 BioMarin Pharmaceutical Inc. Common 09061G101 22867 270613 SH SOLE 270613 0 0 bluebird bio, Inc. Common 09609G100 3870 84194 SH SOLE 84194 0 0 Blueprint Medicines Corporation Common 09627Y109 8148 139336 SH SOLE 139336 0 0 Boston Scientific Corporation Common 101137107 19175 587662 SH SOLE 587662 0 0 BridgeBio Pharma, Inc. Common 10806X102 1138 39228 SH SOLE 39228 0 0 Bristol-Myers Squibb Company Common 110122108 47097 844932 SH SOLE 844932 0 0 Bristol-Myers Squibb Company Right 110122157 5600 1473710 SH SOLE 1473710 0 0 Celldex Therapeutics, Inc. Common 15117B202 12 7053 SH SOLE 7053 0 0 Cellectis Sponsored ADR 15117K103 1013 110147 SH SOLE 110147 0 0 Centene Corporation Common 15135B101 17122 288194 SH SOLE 288194 0 0 Cerner Corporation Common 156782104 5134 81500 SH SOLE 81500 0 0 Charles River Laboratories International, Inc. Common 159864107 2331 18467 SH SOLE 18467 0 0 Cidara Therapeutics, Inc. Common 171757107 484 195256 SH SOLE 195256 0 0 Cigna Corporation Common 125523100 25276 142655 SH SOLE 142655 0 0 Clearside Biomedical, Inc. Common 185063104 281 165330 SH SOLE 165330 0 0 Coherus Biosciences, Inc. Common 19249H103 1811 111663 SH SOLE 111663 0 0 Community Health Systems, Inc. Common 203668108 393 117735 SH SOLE 117735 0 0 Community Healthcare Trust Incorporated Common 20369C106 570 14900 SH SOLE 14900 0 0 CRISPR Therapeutics AG Namen AKT H17182108 3233 76222 SH SOLE 76222 0 0 CVS Health Corporation Common 126650100 29546 497986 SH SOLE 497986 0 0 CymaBay Therapeutics, Inc. Common 23257D103 130 88102 SH SOLE 88102 0 0 Danaher Corporation Common 235851102 22056 159352 SH SOLE 159352 0 0 Deciphera Pharmaceuticals, Inc. Common 24344T101 2527 61370 SH SOLE 61370 0 0 DENTSPLY SIRONA Inc. Common 24906P109 4455 114736 SH SOLE 114736 0 0 Diversified Healthcare Trust Common 25525P107 1299 357720 SH SOLE 357720 0 0 Editas Medicine, Inc. Common 28106W103 2582 130201 SH SOLE 130201 0 0 Edwards Lifesciences Corporation Common 28176E108 12710 67382 SH SOLE 67382 0 0 Eidos Therapeutics, Inc. Common 28249H104 980 20000 SH SOLE 20000 0 0 Eli Lilly and Company Common 532457108 35883 258669 SH SOLE 258669 0 0 Endo International plc Shares G30401106 1967 531570 SH SOLE 531570 0 0 Epizyme, Inc. Common 29428V104 3222 207752 SH SOLE 207752 0 0 Esperion Therapeutics, Inc. Common 29664W105 1311 41577 SH SOLE 41577 0 0 Evolent Health, Inc. Common 30050B101 1254 231027 SH SOLE 231027 0 0 Exact Sciences Corporation Common 30063P105 1342 23133 SH SOLE 23133 0 0 Exelixis, Inc. Common 30161Q104 8870 515125 SH SOLE 515125 0 0 Fate Therapeutics, Inc. Common 31189P102 3680 165672 SH SOLE 165672 0 0 FibroGen, Inc. Common 31572Q808 6751 194270 SH SOLE 194270 0 0 Five Star Senior Living Inc. Common 33832D205 67 24237 SH SOLE 24237 0 0 Galapagos NV Sponsored ADR 36315X101 1282 6543 SH SOLE 6543 0 0 Galera Therapeutics, Inc. Common 36338D108 3958 416666 SH SOLE 416666 0 0 Genmab A/S Sponsored ADS 372303206 3139 148148 SH SOLE 148148 0 0 Gilead Sciences, Inc. Common 375558103 141170 1888305 SH SOLE 1888305 0 0 GlaxoSmithKline PLC Shares 37733W105 7838 206868 SH SOLE 206868 0 0 Global Blood Therapeutics, Inc. Common 37890U108 6033 118083 SH SOLE 118083 0 0 Global Medical REIT Inc. Common 37954A204 1770 174897 SH SOLE 174897 0 0 Grifols, S.A. Sponsored ADR 398438408 954 47373 SH SOLE 47373 0 0 Guardant Health, Inc. Common 40131M109 1646 23656 SH SOLE 23656 0 0 GW Pharmaceuticals plc ADS 36197T103 4387 50101 SH SOLE 50101 0 0 Halozyme Therapeutics, Inc. Common 40637H109 1258 69917 SH SOLE 69917 0 0 HCA Healthcare, Inc. Common 40412C101 7532 83833 SH SOLE 83833 0 0 Health Care Select Sector SPDR Fund SBI Healthcare 81369Y209 891 10055 SH SOLE 10055 0 0 Healthcare Realty Trust Incorporated Common 421946104 2905 104024 SH SOLE 104024 0 0 Healthcare Trust of America, Inc. Common 42225P501 1716 70662 SH SOLE 70662 0 0 HealthEquity, Inc. Common 42226A107 1382 27310 SH SOLE 27310 0 0 Healthpeak Properties, Inc. Common 42250P103 3587 150392 SH SOLE 150392 0 0 Heron Therapeutics, Inc. Common 427746102 1540 131183 SH SOLE 131183 0 0 Hologic, Inc. Common 436440101 1143 32564 SH SOLE 32564 0 0 Horizon Therapeutics plc Shares G46188101 11826 399257 SH SOLE 399257 0 0 Humana Inc. Common 444859102 14486 46130 SH SOLE 46130 0 0 IDEXX Laboratories, Inc. Common 45168D104 9766 40314 SH SOLE 40314 0 0 Illumina, Inc. Common 452327109 72464 265319 SH SOLE 265319 0 0 ImmunoGen, Inc. Common 45253H101 574 168190 SH SOLE 168190 0 0 Immunomedics, Inc. Common 452907108 6566 487103 SH SOLE 487103 0 0 Incyte Corporation Common 45337C102 31653 432246 SH SOLE 432246 0 0 Inogen, Inc. Common 45780L104 2656 51406 SH SOLE 51406 0 0 Insmed Incorporated Common 457669307 1577 98387 SH SOLE 98387 0 0 Intellia Therapeutics, Inc. Common 45826J105 673 55050 SH SOLE 55050 0 0 Intercept Pharmaceuticals, Inc. Common 45845P108 2167 34414 SH SOLE 34414 0 0 Intra-Cellular Therapies, Inc. Common 46116X101 1448 94238 SH SOLE 94238 0 0 Intuitive Surgical, Inc. Common 46120E602 16856 34039 SH SOLE 34039 0 0 Ionis Pharmaceuticals, Inc. Common 462222100 9135 193201 SH SOLE 193201 0 0 Iovance Biotherapeutics, Inc. Common 462260100 6618 221073 SH SOLE 221073 0 0 IQVIA Holdings Inc. Common 46266C105 8873 82266 SH SOLE 82266 0 0 Jazz Pharmaceuticals plc Shares G50871105 6728 67456 SH SOLE 67456 0 0 Johnson & Johnson Common 478160104 109988 838769 SH SOLE 838769 0 0 Kodiak Sciences Inc. Common 50015M109 1104 23153 SH SOLE 23153 0 0 Koninklijke Philips N.V. NY Reg Sh 500472303 2241 55796 SH SOLE 55796 0 0 Laboratory Corporation of America Holdings Sponsored ADR 50540R409 3972 31424 SH SOLE 31424 0 0 Ligand Pharmaceuticals Incorporated Common 53220K504 2225 30590 SH SOLE 30590 0 0 LTC Properties, Inc. Common 502175102 5633 182293 SH SOLE 182293 0 0 Madrigal Pharmaceuticals, Inc. Common 558868105 891 13340 SH SOLE 13340 0 0 Magenta Therapeutics, Inc. Common 55910K108 105 16757 SH SOLE 16757 0 0 Mallinckrodt plc Sponsored ADR G5785G107 65 32980 SH SOLE 32980 0 0 McKesson Corporation Common 58155Q103 8051 59525 SH SOLE 59525 0 0 Medical Properties Trust, Inc. Common 58463J304 7119 411743 SH SOLE 411743 0 0 Medpace Holdings, Inc. Common 58506Q109 1385 18871 SH SOLE 18871 0 0 Medtronic plc Shares G5960L103 40311 447011 SH SOLE 447011 0 0 Menlo Therapeutics Inc. Common 586858102 478 178181 SH SOLE 178181 0 0 Merck & Co., Inc. Common 58933Y105 78679 1022596 SH SOLE 1022596 0 0 Merus N.V. Common N5749R100 257 21215 SH SOLE 21215 0 0 Mettler-Toledo International Inc. Common 592688105 4228 6123 SH SOLE 6123 0 0 Milestone Pharmaceuticals Inc. Common 59935V107 392 213310 SH SOLE 213310 0 0 Mirati Therapeutics, Inc. Common 60468T105 6056 78784 SH SOLE 78784 0 0 Moderna, Inc. Common 60770K107 7612 254146 SH SOLE 254146 0 0 Molecular Templates, Inc. Common 608550109 562 42313 SH SOLE 42313 0 0 Momenta Pharmaceuticals, Inc. Common 60877T100 2484 91316 SH SOLE 91316 0 0 MorphoSys AG Sponsored ADS 617760202 476 19390 SH SOLE 19390 0 0 Mylan N.V. Shares N59465109 15070 1010754 SH SOLE 1010754 0 0 MyoKardia, Inc. Common 62857M105 905 19300 SH SOLE 19300 0 0 National Health Investors, Inc. Common 63633D104 497 10038 SH SOLE 10038 0 0 Nektar Therapeutics Common 640268108 4696 263079 SH SOLE 263079 0 0 Neurocrine Biosciences, Inc. Common 64125C109 17842 206150 SH SOLE 206150 0 0 New Senior Investment Group Inc. Common 648691103 656 256398 SH SOLE 256398 0 0 Novartis AG Sponsored ADR 66987V109 14828 179847 SH SOLE 179847 0 0 Novavax, Inc. Common 670002401 388 28550 SH SOLE 28550 0 0 Novo Nordisk A/S Sponsored ADR 670100205 8067 134005 SH SOLE 134005 0 0 NovoCure Ltd. Ordinary Shares G6674U108 7235 107438 SH SOLE 107438 0 0 Omega Healthcare Investors, Inc. Common 681936100 8133 306433 SH SOLE 306433 0 0 Ovid Therapeutics Inc. Sponsored ADR 690469101 1111 372733 SH SOLE 372733 0 0 Pacific Biosciences of California, Inc. Common 69404D108 1516 495495 SH SOLE 495495 0 0 PerkinElmer, Inc. Common 714046109 2898 38494 SH SOLE 38494 0 0 Perrigo Company plc Shares G97822103 520 10818 SH SOLE 10818 0 0 Pfizer Inc. Common 717081103 59413 1820248 SH SOLE 1820248 0 0 Physicians Realty Trust Common 71943U104 6911 495733 SH SOLE 495733 0 0 Pieris Pharmaceuticals, Inc. Common 720795103 3304 1449269 SH SOLE 1449269 0 0 Portola Pharmaceuticals, Inc. Sponsored ADR 737010108 779 109246 SH SOLE 109246 0 0 PRA Health Sciences, Inc. Common 69354M108 11917 143508 SH SOLE 143508 0 0 PTC Therapeutics, Inc. Common 69366J200 5390 120827 SH SOLE 120827 0 0 Puma Biotechnology, Inc. Common 74587V107 602 71340 SH SOLE 71340 0 0 Quest Diagnostics Incorporated Common 74834L100 1688 21025 SH SOLE 21025 0 0 Quorum Health Corporation Common 74909E106 11 23725 SH SOLE 23725 0 0 Quotient Ltd. Common G73268107 1027 260030 SH SOLE 260030 0 0 Ra Pharmaceuticals, Inc. Common 74933V108 1716 35743 SH SOLE 35743 0 0 Reata Pharmaceuticals, Inc. Class A 75615P103 5071 35129 SH SOLE 35129 0 0 Regeneron Pharmaceuticals, Inc. Common 75886F107 83438 170878 SH SOLE 170878 0 0 REGENXBIO Inc. Common 75901B107 703 21700 SH SOLE 21700 0 0 ResMed Inc. Common 761152107 2626 17831 SH SOLE 17831 0 0 Revance Therapeutics, Inc. Common 761330109 1270 85840 SH SOLE 85840 0 0 Rocket Pharmaceuticals, Inc. Common 77313F106 2895 207555 SH SOLE 207555 0 0 Rubius Therapeutics, Inc. Common 78116T103 694 155982 SH SOLE 155982 0 0 Sabra Health Care REIT, Inc. Common 78573L106 5576 510660 SH SOLE 510660 0 0 Sage Therapeutics Inc Common 78667J108 2763 96211 SH SOLE 96211 0 0 Sangamo Therapeutics, Inc. Common 800677106 954 149835 SH SOLE 149835 0 0 Sanofi Sponsored ADR 80105N105 14312 327367 SH SOLE 327367 0 0 Sarepta Therapeutics, Inc. Common 803607100 13707 140129 SH SOLE 140129 0 0 Seattle Genetics, Inc. Common 812578102 24752 214530 SH SOLE 214530 0 0 Smith & Nephew plc Shares 83175M205 3571 99560 SH SOLE 99560 0 0 Spectrum Pharmaceuticals, Inc. Common 84763A108 267 114670 SH SOLE 114670 0 0 STERIS plc Shares G8473T100 1570 11218 SH SOLE 11218 0 0 Stryker Corporation Common 863667101 22609 135795 SH SOLE 135795 0 0 Sutro Biopharma, Inc. Common 869367102 6541 641268 SH SOLE 641268 0 0 Syneos Health, Inc. Class A 87166B102 4257 108001 SH SOLE 108001 0 0 Takeda Pharmaceutical Company Ltd. Sponsored ADS 874060205 3190 210146 SH SOLE 210146 0 0 Teleflex Incorporated Common 879369106 5052 17252 SH SOLE 17252 0 0 Tenet Healthcare Corporation Common 88033G407 1393 96736 SH SOLE 96736 0 0 Tetraphase Pharmaceuticals, Inc. Common 88165N204 55 42965 SH SOLE 42965 0 0 Teva Pharmaceutical Industries Ltd. Sponsored ADR 881624209 7057 785851 SH SOLE 785851 0 0 Theravance Biopharma, Inc. Common G8807B106 5288 228836 SH SOLE 228836 0 0 Thermo Fisher Scientific Inc. Common 883556102 31770 112025 SH SOLE 112025 0 0 Trillium Therapeutics Inc. Common 89620X506 1810 448049 SH SOLE 448049 0 0 Turning Point Therapeutics, Inc. Common 90041T108 254 5677 SH SOLE 5677 0 0 Ultragenyx Pharmaceutical Inc. Common 90400D108 4331 97480 SH SOLE 97480 0 0 uniQure N.V. Shares N90064101 2081 43849 SH SOLE 43849 0 0 United Therapeutics Corporation Class B 91307C102 6023 63513 SH SOLE 63513 0 0 Unitedhealth Group Incorporated Common 91324P102 56566 226827 SH SOLE 226827 0 0 Universal Health Realty Income Trust Shares 91359E105 1135 11258 SH SOLE 11258 0 0 Ventas, Inc. Common 92276F100 5577 208108 SH SOLE 208108 0 0 Verona Pharma plc Sponsored ADR 925050106 1043 253179 SH SOLE 253179 0 0 Vertex Pharmaceuticals Incorporated Common 92532F100 115579 485730 SH SOLE 485730 0 0 Viela Bio, Inc. Common 926613100 19 500 SH SOLE 500 0 0 Waters Corporation Common 941848103 4733 26000 SH SOLE 26000 0 0 WaVe Life Sciences Ltd. Shares Y95308105 1201 128146 SH SOLE 128146 0 0 Welltower Inc. Common 95040Q104 9297 203083 SH SOLE 203083 0 0 Xencor, Inc. Common 98401F105 4429 148231 SH SOLE 148231 0 0 Y-mAbs Therapeutics, Inc. Common 984241109 1998 76548 SH SOLE 76548 0 0 Zai Lab Ltd. ADR 98887Q104 1932 37523 SH SOLE 37523 0 0 Zimmer Biomet Holdings, Inc. Common 98956P102 7901 78168 SH SOLE 78168 0 0 Zoetis Inc. Class A 98978V103 17883 151952 SH SOLE 151952 0 0 Zogenix, Inc. Common 98978L204 5327 215406 SH SOLE 215406 0 0 Zymeworks Inc. Common 98985W102 539 15192 SH SOLE 15192 0 0