Chief Compliance Officer

0001104659-18-051430.txt : 20180813 0001104659-18-051430.hdr.sgml : 20180813 20180813135001 ACCESSION NUMBER: 0001104659-18-051430 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20180630 FILED AS OF DATE: 20180813 DATE AS OF CHANGE: 20180813 EFFECTIVENESS DATE: 20180813 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Tekla Capital Management LLC CENTRAL INDEX KEY: 0001300336 IRS NUMBER: 010628853 STATE OF INCORPORATION: DE FISCAL YEAR END: 0930 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-10950 FILM NUMBER: 181011717 BUSINESS ADDRESS: STREET 1: 100 FEDERAL STREET STREET 2: 19TH FLOOR CITY: BOSTON STATE: MA ZIP: 02110 BUSINESS PHONE: 617 772-8500 MAIL ADDRESS: STREET 1: 100 FEDERAL STREET STREET 2: 19TH FLOOR CITY: BOSTON STATE: MA ZIP: 02110 FORMER COMPANY: FORMER CONFORMED NAME: Hambrecht & Quist Capital Management LLC DATE OF NAME CHANGE: 20040811 13F-HR 1 primary_doc.xml 13F-HR LIVE 0001300336 XXXXXXXX 06-30-2018 06-30-2018 false Tekla Capital Management LLC

100 FEDERAL STREET 19TH FLOOR BOSTON MA 02110

13F HOLDINGS REPORT 028-10950 N Laura Woodward Chief Compliance Officer 617-772-8500 /s/ Laura Woodward Boston MA 08-13-2018 0 180 2635196 false INFORMATION TABLE 2 a18-15239_1informationtable.xml INFORMATION TABLE Abbott Laboratories Common 002824100 38242 627019 SH SOLE 627019 0 0 AbbVie Inc. Common 00287Y109 47590 513658 SH SOLE 513658 0 0 AC Immune SA Shares H00263105 1598 171813 SH SOLE 171813 0 0 Acadia Healthcare Company, Inc. Common 00404A109 11144 272400 SH SOLE 272400 0 0 ACADIA Pharmaceuticals Inc. Common 004225108 1431 93689 SH SOLE 93689 0 0 Acceleron Pharma Inc. Common 00434H108 8286 170766 SH SOLE 170766 0 0 Achillion Pharmaceuticals, Inc. Common 00448Q201 1743 616000 SH SOLE 616000 0 0 Adaptimmune Therapeutics plc Sponsored ADR 00653A107 10154 855468 SH SOLE 855468 0 0 Aegerion Pharmaceuticals, Inc. Note 2.00% 8/15/19 00767EAB8 8436 13000000 PRN SOLE 13000000 0 0 Aerpio Pharmaceuticals, Inc. Common 00810B105 3175 765000 SH SOLE 765000 0 0 Aetna Inc. Common 00817Y108 17822 97122 SH SOLE 97122 0 0 Affimed N.V. Common N01045108 2681 1624792 SH SOLE 1624792 0 0 Agios Pharmaceuticals, Inc. Common 00847X104 237 2810 SH SOLE 2810 0 0 Akebia Therapeutics, Inc. Common 00972D105 2661 266612 SH SOLE 266612 0 0 Albireo Pharma, Inc. Common 01345P106 4438 125000 SH SOLE 125000 0 0 Alexion Pharmaceuticals, Inc. Common 015351109 54429 438416 SH SOLE 438416 0 0 Alkermes plc Shares G01767105 7040 171042 SH SOLE 171042 0 0 Allergan plc Shares G0177J108 41486 248836 SH SOLE 248836 0 0 Alliqua BioMedical, Inc. Common 019621309 338 165000 SH SOLE 165000 0 0 Alnylam Pharmaceuticals, Inc. Common 02043Q107 12841 130376 SH SOLE 130376 0 0 Amarin Corporation plc Sponsored ADR 023111206 1477 478149 SH SOLE 478149 0 0 AmerisourceBergen Corporation Common 03073E105 7905 92707 SH SOLE 92707 0 0 Amgen Inc. Common 031162100 129322 700588 SH SOLE 700588 0 0 Amicus Therapeutics, Inc. Common 03152W109 13672 875304 SH SOLE 875304 0 0 Anthem, Inc. Common 036752103 26334 110633 SH SOLE 110633 0 0 ARCA biopharma, Inc. Common 00211Y407 451 811227 SH SOLE 811227 0 0 Ardelyx, Inc. Common 039697107 2366 639370 SH SOLE 639370 0 0 Arena Pharmaceuticals, Inc. Common 040047607 4088 93767 SH SOLE 93767 0 0 argenx SE Sponsored ADR 04016X101 3226 38931 SH SOLE 38931 0 0 Array BioPharma Inc. Common 04269X105 4297 256056 SH SOLE 256056 0 0 Ascendis Pharma A/S Sponsored ADR 04351P101 2921 43914 SH SOLE 43914 0 0 AstraZeneca PLC Sponsored ADR 046353108 27347 778888 SH SOLE 778888 0 0 Avadel Pharmaceuticals plc Sponsored ADR 05337M104 4993 814588 SH SOLE 814588 0 0 Bausch Health Companies Inc. Common 91911K102 4462 192000 SH SOLE 192000 0 0 Baxter International Inc. Sponsored ADR 071813109 9904 134124 SH SOLE 134124 0 0 Becton, Dickinson and Company Common 075887109 12691 52978 SH SOLE 52978 0 0 BeiGene, Ltd. Sponsored ADR 07725L102 8422 54785 SH SOLE 54785 0 0 Bellicum Pharmaceuticals, Inc. Common 079481107 443 60000 SH SOLE 60000 0 0 Biogen Inc. Common 09062X103 117244 403955 SH SOLE 403955 0 0 BioMarin Pharmaceutical Inc. Common 09061G101 13239 140538 SH SOLE 140538 0 0 bluebird bio, Inc. Common 09609G100 11331 72198 SH SOLE 72198 0 0 Blueprint Medicines Corporation Common 09627Y109 9268 146001 SH SOLE 146001 0 0 Boston Scientific Corporation Common 101137107 14963 457585 SH SOLE 457585 0 0 Bristol-Myers Squibb Company Common 110122108 36028 651030 SH SOLE 651030 0 0 Cardinal Health, Inc. Common 14149Y108 308 6300 SH SOLE 6300 0 0 Celgene Corporation Common 151020104 99392 1251470 SH SOLE 1251470 0 0 Celldex Therapeutics, Inc. Common 15117B103 53 105800 SH SOLE 105800 0 0 Cellectis S.A. Sponsored ADR 15117K103 8995 317950 SH SOLE 317950 0 0 Centene Corporation Common 15135B101 22772 184819 SH SOLE 184819 0 0 Charles River Laboratories International, Inc. Common 159864107 2545 22670 SH SOLE 22670 0 0 Cidara Therapeutics, Inc. Common 171757107 826 158784 SH SOLE 158784 0 0 Cigna Corporation Common 125509109 6876 40461 SH SOLE 40461 0 0 Clearside Biomedical, Inc. Common 185063104 884 82665 SH SOLE 82665 0 0 Clovis Oncology, Inc. Common 189464100 3428 75400 SH SOLE 75400 0 0 Coherus Biosciences, Inc. Common 19249H103 3372 240843 SH SOLE 240843 0 0 Community Health Systems, Inc. Common 203668108 677 203935 SH SOLE 203935 0 0 CRISPR Therapeutics AG Common H17182108 10480 178348 SH SOLE 178348 0 0 CVS Health Corporation Common 126650100 23586 366521 SH SOLE 366521 0 0 CymaBay Therapeutics, Inc. Common 23257D103 2281 169962 SH SOLE 169962 0 0 Danaher Corporation Common 235851102 19033 192871 SH SOLE 192871 0 0 Depomed, Inc. Common 249908104 420 62973 SH SOLE 62973 0 0 Dermira, Inc. Common 24983L104 2155 234200 SH SOLE 234200 0 0 Diplomat Pharmacy, Inc. Common 25456K101 11221 439001 SH SOLE 439001 0 0 Editas Medicine, Inc. Common 28106W103 4937 137801 SH SOLE 137801 0 0 Edwards Lifesciences Corporation Common 28176E108 9648 66275 SH SOLE 66275 0 0 Egalet Corporation Note 5.50% 4/1/20 28226BAB0 2445 7000000 PRN SOLE 7000000 0 0 Eli Lilly and Company Common 532457108 33288 390108 SH SOLE 390108 0 0 Endo International plc Shares G30401106 10169 1078414 SH SOLE 1078414 0 0 Epizyme, Inc. Common 29428V104 6576 485325 SH SOLE 485325 0 0 Esperion Therapeutics, Inc. Common 29664W105 7418 189287 SH SOLE 189287 0 0 Evolent Health, Inc. Class A 30050B101 2579 122500 SH SOLE 122500 0 0 Exelixis, Inc. Common 30161Q104 9211 428022 SH SOLE 428022 0 0 Express Scripts Holding Company Common 30219G108 8223 106500 SH SOLE 106500 0 0 FibroGen, Inc. Common 31572Q808 11156 178207 SH SOLE 178207 0 0 Foamix Pharmaceuticals Ltd. Shares M46135105 4661 930398 SH SOLE 930398 0 0 Galapagos NV Sponsored ADR 36315X101 8003 86815 SH SOLE 86815 0 0 Gilead Sciences, Inc. Common 375558103 146192 2063699 SH SOLE 2063699 0 0 GlaxoSmithKline plc Shares 37733W105 14471 359000 SH SOLE 359000 0 0 Global Blood Therapeutics, Inc. Common 37890U108 2684 59390 SH SOLE 59390 0 0 Global Medical REIT Inc. Common 37954A204 650 73400 SH SOLE 73400 0 0 GW Pharmaceuticals plc ADS 36197T103 9977 71497 SH SOLE 71497 0 0 HCA Healthcare, Inc. Common 40412C101 7704 75090 SH SOLE 75090 0 0 HCP, Inc. Common 40414L109 1175 45500 SH SOLE 45500 0 0 Healthcare Realty Trust Incorporated Common 421946104 1977 68000 SH SOLE 68000 0 0 Healthcare Trust of America, Inc. Class A 42225P501 1240 46000 SH SOLE 46000 0 0 Henry Schein, Inc. Common 806407102 2281 31400 SH SOLE 31400 0 0 Hologic, Inc. Common 436440101 777 19546 SH SOLE 19546 0 0 Horizon Pharma plc Shares G4617B105 2698 162900 SH SOLE 162900 0 0 Humana Inc. Common 444859102 31267 105053 SH SOLE 105053 0 0 IDEXX Laboratories, Inc. Common 45168D104 28247 129608 SH SOLE 129608 0 0 Illumina, Inc. Common 452327109 79456 284492 SH SOLE 284492 0 0 Incyte Corporation Common 45337C102 43245 645442 SH SOLE 645442 0 0 Innoviva, Inc. Common 45781M101 2230 161603 SH SOLE 161603 0 0 Intellia Therapeutics, Inc. Common 45826J105 4580 167381 SH SOLE 167381 0 0 Intuitive Surgical, Inc. Common 46120E602 11234 23479 SH SOLE 23479 0 0 Ionis Pharmaceuticals, Inc. Common 462222100 3452 82838 SH SOLE 82838 0 0 Iovance Biotherapeutics, Inc. Common 462260100 427 33395 SH SOLE 33395 0 0 Jazz Pharmaceuticals plc Shares G50871105 19031 110452 SH SOLE 110452 0 0 Johnson & Johnson Common 478160104 108367 893082 SH SOLE 893082 0 0 Jounce Therapeutics, Inc. Common 481116101 78 10127 SH SOLE 10127 0 0 LeMaitre Vascular, Inc. Common 525558201 909 27150 SH SOLE 27150 0 0 LivaNova PLC Common G5509L101 628 6287 SH SOLE 6287 0 0 Loxo Oncology, Inc. Common 548862101 1798 10365 SH SOLE 10365 0 0 LTC Properties, Inc. Common 502175102 8961 209673 SH SOLE 209673 0 0 Mallinckrodt plc Shares G5785G107 1155 61900 SH SOLE 61900 0 0 Masimo Corporation Common 574795100 4689 48020 SH SOLE 48020 0 0 McKesson Corporation Common 58155Q103 13180 98797 SH SOLE 98797 0 0 Medical Properties Trust, Inc. Common 58463J304 12055 858586 SH SOLE 858586 0 0 The Medicines Company Common 584688105 8762 238741 SH SOLE 238741 0 0 Medtronic plc Shares G5960L103 36272 423693 SH SOLE 423693 0 0 Merck & Co., Inc. Common 58933Y105 77940 1284022 SH SOLE 1284022 0 0 Merus N.V. Common N5749R100 9425 414115 SH SOLE 414115 0 0 Molecular Templates, Inc. Common 608550109 754 144110 SH SOLE 144110 0 0 Mylan N.V. Shares N59465109 59885 1657017 SH SOLE 1657017 0 0 NanoString Technologies, Inc. Common 63009R109 1016 74250 SH SOLE 74250 0 0 Nektar Therapeutics Common 640268108 9218 188769 SH SOLE 188769 0 0 Neurocrine Biosciences, Inc. Common 64125C109 26502 269769 SH SOLE 269769 0 0 Nevro Corp. Common 64157F103 4231 52990 SH SOLE 52990 0 0 New Senior Investment Group Inc. Common 648691103 4004 528919 SH SOLE 528919 0 0 NewLink Genetics Corporation Common 651511107 976 205026 SH SOLE 205026 0 0 Novartis AG Sponsored ADR 66987V109 22346 295820 SH SOLE 295820 0 0 Novavax, Inc. Common 670002104 765 571000 SH SOLE 571000 0 0 Novo Nordisk A/S Sponsored ADR 670100205 6268 135900 SH SOLE 135900 0 0 NuCana plc Common 67022C106 187 9823 SH SOLE 9823 0 0 NuVasive, Inc. Common 670704105 1021 19580 SH SOLE 19580 0 0 Omega Healthcare Investors, Inc. Common 681936100 17973 579785 SH SOLE 579785 0 0 Ovid Therapeutics Inc. Common 690469101 4179 535824 SH SOLE 535824 0 0 Perrigo Company plc Shares G97822103 2720 37300 SH SOLE 37300 0 0 Pfizer Inc. Common 717081103 85609 2359687 SH SOLE 2359687 0 0 Physicians Realty Trust Common 71943U104 6233 391016 SH SOLE 391016 0 0 Pieris Pharmaceuticals, Inc. Common 720795103 10583 2087380 SH SOLE 2087380 0 0 Portola Pharmaceuticals, Inc. Common 737010108 3398 89978 SH SOLE 89978 0 0 PRA Health Sciences, Inc. Common 69354M108 3030 32460 SH SOLE 32460 0 0 Protagonist Therapeutics, Inc. Common 74366E102 1472 219042 SH SOLE 219042 0 0 Puma Biotechnology, Inc. Common 74587V107 4930 83340 SH SOLE 83340 0 0 Quorum Health Corporation Common 74909E106 119 23725 SH SOLE 23725 0 0 Ra Pharmaceuticals, Inc. Common 74933V108 2189 219952 SH SOLE 219952 0 0 Regeneron Pharmaceuticals, Inc. Common 75886F107 50450 146237 SH SOLE 146237 0 0 ResMed Inc. Common 761152107 6073 58630 SH SOLE 58630 0 0 Revance Therapeutics, Inc. Common 761330109 2139 77919 SH SOLE 77919 0 0 The RMR Group Inc. Class A 74967R106 584 7441 SH SOLE 7441 0 0 Sabra Health Care REIT, Inc. Common 78573L106 15746 724606 SH SOLE 724606 0 0 Sage Therapeutics, Inc. Common 78667J108 22480 143614 SH SOLE 143614 0 0 Sangamo Therapeutics, Inc. Common 800677106 1711 120512 SH SOLE 120512 0 0 Sanofi Common 80105N105 7198 179900 SH SOLE 179900 0 0 Sarepta Therapeutics, Inc. Common 803607100 30995 234489 SH SOLE 234489 0 0 Seattle Genetics, Inc. Common 812578102 18550 279417 SH SOLE 279417 0 0 Senior Housing Properties Trust Shares 81721M109 11696 646554 SH SOLE 646554 0 0 Shire plc Shares 82481R106 6113 36216 SH SOLE 36216 0 0 Smith & Nephew plc Sponsored ADR 83175M205 1657 44148 SH SOLE 44148 0 0 Spark Therapeutics, Inc. Common 84652J103 1825 22046 SH SOLE 22046 0 0 SPDR S&P Biotech ETF S&P Biotech ETF 78464A870 23841 250460 SH SOLE 250460 0 0 STERIS plc Shares G84720104 2353 22403 SH SOLE 22403 0 0 Stryker Corporation Common 863667101 23072 136631 SH SOLE 136631 0 0 Syndax Pharmaceuticals, Inc. Common 87164F105 1404 200000 SH SOLE 200000 0 0 Teleflex Incorporated Common 879369106 1711 6379 SH SOLE 6379 0 0 Teligent, Inc. Common 87960W104 3136 906362 SH SOLE 906362 0 0 Tenet Healthcare Corporation Common 88033G407 5522 164500 SH SOLE 164500 0 0 TESARO, Inc. Common 881569107 4223 94970 SH SOLE 94970 0 0 Tetraphase Pharmaceuticals, Inc. Common 88165N105 3068 859322 SH SOLE 859322 0 0 Teva Pharmaceutical Industries Limited Sponsored ADR 881624209 26359 1083843 SH SOLE 1083843 0 0 TherapeuticsMD, Inc. Common 88338N107 1463 234384 SH SOLE 234384 0 0 Theravance Biopharma, Inc. Common G8807B106 183 8083 SH SOLE 8083 0 0 Thermo Fisher Scientific Inc. Common 883556102 31629 152695 SH SOLE 152695 0 0 Trillium Therapeutics Inc. Common 89620X506 2810 468399 SH SOLE 468399 0 0 Ultragenyx Pharmaceutical Inc. Common 90400D108 5916 76958 SH SOLE 76958 0 0 uniQure N.V. Shares N90064101 1427 37741 SH SOLE 37741 0 0 United Therapeutics Corporation Class B 91307C102 4669 41261 SH SOLE 41261 0 0 Unitedhealth Group Incorporated Common 91324P102 104347 425317 SH SOLE 425317 0 0 Varian Medical Systems, Inc. Common 92220P105 2983 26227 SH SOLE 26227 0 0 Ventas, Inc. Common 92276F100 5609 98496 SH SOLE 98496 0 0 Verona Pharma plc Sponsored ADR 925050106 3781 275000 SH SOLE 275000 0 0 Vertex Pharmaceuticals Incorporated Common 92532F100 98835 581522 SH SOLE 581522 0 0 Welltower Inc. 6.50% Preferred Perpetual 95040Q203 11890 200000 SH SOLE 200000 0 0 Welltower Inc. Common 95040Q104 2856 45560 SH SOLE 45560 0 0 Wright Medical Group N.V. Ordinary Shares N96617118 6926 266781 SH SOLE 266781 0 0 Xenon Pharmaceuticals Inc. Common 98420N105 1507 163819 SH SOLE 163819 0 0 Zimmer Biomet Holdings, Inc. Common 98956P102 13244 118846 SH SOLE 118846 0 0 Zoetis, Inc. Class A 98978V103 3046 35760 SH SOLE 35760 0 0 Zogenix, Inc. Common 98978L204 1563 35352 SH SOLE 35352 0 0