Chief Compliance Officer

0001104659-17-008451.txt : 20170213 0001104659-17-008451.hdr.sgml : 20170213 20170213115355 ACCESSION NUMBER: 0001104659-17-008451 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20161231 FILED AS OF DATE: 20170213 DATE AS OF CHANGE: 20170213 EFFECTIVENESS DATE: 20170213 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Tekla Capital Management LLC CENTRAL INDEX KEY: 0001300336 IRS NUMBER: 010628853 STATE OF INCORPORATION: DE FISCAL YEAR END: 0930 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-10950 FILM NUMBER: 17597168 BUSINESS ADDRESS: STREET 1: 100 FEDERAL STREET STREET 2: 19TH FLOOR CITY: BOSTON STATE: MA ZIP: 02110 BUSINESS PHONE: 617 772-8500 MAIL ADDRESS: STREET 1: 100 FEDERAL STREET STREET 2: 19TH FLOOR CITY: BOSTON STATE: MA ZIP: 02110 FORMER COMPANY: FORMER CONFORMED NAME: Hambrecht & Quist Capital Management LLC DATE OF NAME CHANGE: 20040811 13F-HR 1 primary_doc.xml 13F-HR LIVE 0001300336 XXXXXXXX 12-31-2016 12-31-2016 false Tekla Capital Management LLC

100 FEDERAL STREET 19TH FLOOR BOSTON MA 02110

13F HOLDINGS REPORT 028-10950 N Laura Woodward Chief Compliance Officer 617-772-8500 /s/ Laura Woodward Boston MA 02-13-2017 0 143 2347509 false INFORMATION TABLE 2 a17-1633_1informationtable.xml INFORMATION TABLE Abbott Laboratories Common 002824100 60830 1583700 SH SOLE 1583700 0 0 AbbVie Inc. Common 00287Y109 10 156 SH SOLE 156 0 0 Acadia Healthcare Company, Inc. Common 00404A109 2148 64900 SH SOLE 64900 0 0 ACADIA Pharmaceuticals Inc. Common 004225108 3224 111800 SH SOLE 111800 0 0 Accelerate Diagnostics, Inc. Common 00430H102 2490 120000 SH SOLE 120000 0 0 Acceleron Pharma, Inc. Common 00434H108 1390 54450 SH SOLE 54450 0 0 Achillion Pharmaceuticals, Inc. Common 00448Q201 1833 443851 SH SOLE 443851 0 0 Adamas Pharmaceuticals, Inc. Common 00548A106 2121 125504 SH SOLE 125504 0 0 Adaptimmune Therapeutics plc Sponsored ADR 00653A107 2294 566368 SH SOLE 566368 0 0 Aegerion Pharmaceuticals, Inc. Note 2.00% 5/15/19 00767EAB8 9263 13000000 PRN SOLE 13000000 0 0 Affimed NV Common N01045108 530 294213 SH SOLE 294213 0 0 Akorn, Inc. Common 009728106 7154 327735 SH SOLE 327735 0 0 Alexion Pharmaceuticals, Inc. Common 015351109 97379 795905 SH SOLE 795905 0 0 Allergan plc Common G0177J108 91162 434086 SH SOLE 434086 0 0 Allergan plc Preferred Convertible G0177J116 3812 5000 SH SOLE 5000 0 0 Alliqua BioMedical, Inc. Common 019621200 974 1650000 SH SOLE 1650000 0 0 Allscripts Healthcare Solutions, Inc. Common 01988P108 1772 173600 SH SOLE 173600 0 0 Alnylam Pharmaceuticals, Inc. Common 02043Q107 9135 243995 SH SOLE 243995 0 0 AmerisourceBergen Corporation Common 03073E105 25856 330687 SH SOLE 330687 0 0 Amgen Inc. Common 031162100 47027 321640 SH SOLE 321640 0 0 Amicus Therapeutics, Inc. Common 03152W109 2081 418730 SH SOLE 418730 0 0 ARCA biopharma, Inc. Common 00211Y407 2312 811227 SH SOLE 811227 0 0 Ardelyx, Inc. Common 039697107 9079 639370 SH SOLE 639370 0 0 AstraZeneca PLC Sponsored ADR 046353108 12671 463800 SH SOLE 463800 0 0 Auris Medical Holding AG Common H03579101 829 774504 SH SOLE 774504 0 0 Becton, Dickinson and Co. Common 075887109 10443 63078 SH SOLE 63078 0 0 BeiGene, Ltd. Sponsored ADR 07725L102 3543 116707 SH SOLE 116707 0 0 Bellicum Pharmaceuticals, Inc. Common 079481107 817 60000 SH SOLE 60000 0 0 Biogen Inc. Common 09062X103 152382 537350 SH SOLE 537350 0 0 BioMarin Pharmaceutical Inc. Common 09061G101 47438 572645 SH SOLE 572645 0 0 bluebird bio, Inc. Common 09609G100 3045 49345 SH SOLE 49345 0 0 Cardinal Health, Inc. Common 14149Y108 10975 152500 SH SOLE 152500 0 0 Care Capital Properties, Inc. Common 141624106 8626 345022 SH SOLE 345022 0 0 Celgene Corporation Common 151020104 163195 1409889 SH SOLE 1409889 0 0 Celldex Therapeutics, Inc. Common 15117B103 375 105800 SH SOLE 105800 0 0 Cellectis S.A. Sponsored ADR 15117K103 5259 310250 SH SOLE 310250 0 0 Centene Corporation Common 15135B101 22604 400000 SH SOLE 400000 0 0 Charles River Laboratories International, Inc. Common 159864107 9722 127600 SH SOLE 127600 0 0 Chimerix, Inc. Common 16934W106 1421 308892 SH SOLE 308892 0 0 Cidara Therapeutics, Inc. Common 171757107 1378 132472 SH SOLE 132472 0 0 Cigna Corporation Common 125509109 11525 86400 SH SOLE 86400 0 0 Coherus Biosciences, Inc. Common 19249H103 2534 90000 SH SOLE 90000 0 0 Community Health Systems, Inc. Common 203668108 1140 203935 SH SOLE 203935 0 0 CVS Health Corporation Common 126650100 32502 411891 SH SOLE 411891 0 0 CytomX Therapeutics, Inc. Common 23284F105 8309 756090 SH SOLE 756090 0 0 DBV Technologies S.A. Sponsored ADR 23306J101 2305 65600 SH SOLE 65600 0 0 Dermira, Inc. Common 24983L104 5011 165200 SH SOLE 165200 0 0 Diplomat Pharmacy, Inc. Common 25456K101 1641 130223 SH SOLE 130223 0 0 Dynavax Technologies Corporation Common 268158201 1363 345050 SH SOLE 345050 0 0 Egalet Corporation Note 5.50% 4/1/20 28226BAB0 6059 7000000 PRN SOLE 7000000 0 0 Eli Lilly & Company Common 532457108 36268 493100 SH SOLE 493100 0 0 Endo International plc Shares G30401106 15063 914548 SH SOLE 914548 0 0 Endologix, Inc. Common 29266S106 2212 386750 SH SOLE 386750 0 0 Epizyme, Inc. Common 29428V104 4840 400000 SH SOLE 400000 0 0 Esperion Therapeutics, Inc. Common 29664W105 1287 102800 SH SOLE 102800 0 0 Exelixis, Inc. Common 30161Q104 8225 551647 SH SOLE 551647 0 0 Flamel Technologies SA Sponsored ADR 338488109 6486 624288 SH SOLE 624288 0 0 Flex Pharma, Inc. Common 33938A105 856 162124 SH SOLE 162124 0 0 Foamix Pharmaceuticals Ltd Shares M46135105 10327 930398 SH SOLE 930398 0 0 Forward Pharma A/S Sponsored ADR 34986J105 2050 136547 SH SOLE 136547 0 0 Galapagos NV Sponsored ADR 36315X101 7429 115738 SH SOLE 115738 0 0 GenMark Diagnostics, Inc. Common 372309104 1143 93349 SH SOLE 93349 0 0 Gilead Sciences, Inc. Common 375558103 181183 2530131 SH SOLE 2530131 0 0 GlaxoSmithKline plc Sponsored ADR 37733W105 13825 359000 SH SOLE 359000 0 0 Global Blood Therapeutics, Inc. Common 37890U108 5510 381300 SH SOLE 381300 0 0 Global Medical REIT Inc. Common 37954A204 655 73400 SH SOLE 73400 0 0 Grifols, S.A. Sponsored ADR 398438408 2668 166000 SH SOLE 166000 0 0 Halozyme Therapeutics, Inc. Common 40637H109 1976 200000 SH SOLE 200000 0 0 HCA Holdings, Inc. Common 40412C101 14081 190232 SH SOLE 190232 0 0 HCP, Inc. Common 40414L109 1352 45500 SH SOLE 45500 0 0 Healthcare Realty Trust, Inc. Common 421946104 2062 68000 SH SOLE 68000 0 0 Healthcare Trust of America, Inc. Class A 42225P501 1339 46000 SH SOLE 46000 0 0 Horizon Pharma plc Shares G4617B105 2636 162900 SH SOLE 162900 0 0 Humana Inc. Common 444859102 33624 164800 SH SOLE 164800 0 0 ICON plc Shares G4705A100 5414 72000 SH SOLE 72000 0 0 IDEXX Laboratories, Inc. Common 45168D104 15521 132352 SH SOLE 132352 0 0 Illumina, Inc. Common 452327109 31570 246560 SH SOLE 246560 0 0 Immunomedics, Inc. Note 4.75% 2/15/20 452907AK4 3960 4000000 PRN SOLE 4000000 0 0 Impax Laboratories, Inc. Common 45256B101 1647 124335 SH SOLE 124335 0 0 Incyte Corporation Common 45337C102 88284 880461 SH SOLE 880461 0 0 Intellia Therapeutics, Inc. Common 45826J105 942 71842 SH SOLE 71842 0 0 iShares Nasdaq Biotechnology ETF ETF 464287556 15304 57670 SH SOLE 57670 0 0 Jazz Pharmaceuticals plc Shares G50871105 36134 331411 SH SOLE 331411 0 0 Johnson & Johnson Common 478160104 51062 443212 SH SOLE 443212 0 0 Juno Therapeutics, Inc. Common 48205A109 1073 56900 SH SOLE 56900 0 0 Karyopharm Therapeutics Inc. Common 48576U106 4703 500324 SH SOLE 500324 0 0 LTC Properties, Inc. Common 502175102 6399 136212 SH SOLE 136212 0 0 Mallinckrodt plc Shares G5785G107 3084 61900 SH SOLE 61900 0 0 McKesson Corporation Common 58155Q103 2107 15000 SH SOLE 15000 0 0 Medical Properties Trust, Inc. Common 58463J304 12395 1007717 SH SOLE 1007717 0 0 The Medicines Company Common 584688105 26189 771638 SH SOLE 771638 0 0 Medtronic plc Shares G5960L103 44378 623030 SH SOLE 623030 0 0 Merck & Co., Inc. Common 58933Y105 70547 1198349 SH SOLE 1198349 0 0 Merus B.V. Common N5749R100 10115 479150 SH SOLE 479150 0 0 Molina Healthcare, Inc. Common 60855R100 21842 402541 SH SOLE 402541 0 0 Momenta Pharmaceuticals, Inc. Common 60877T100 4614 306600 SH SOLE 306600 0 0 Mylan N.V. Shares N59465109 43321 1135552 SH SOLE 1135552 0 0 Myovant Sciences Ltd. Common G637AM102 4976 400000 SH SOLE 400000 0 0 Nabriva Therapeutics AG Sponsored ADR 62957M104 2083 350000 SH SOLE 350000 0 0 Natera, Inc. Common 632307104 10332 882358 SH SOLE 882358 0 0 Neurocrine Biosciences, Inc. Common 64125C109 15165 391869 SH SOLE 391869 0 0 New Senior Investment Group Inc. Common 648691103 5561 567997 SH SOLE 567997 0 0 Novartis AG Sponsored ADR 66987V109 18123 248800 SH SOLE 248800 0 0 Novavax, Inc. Common 670002104 719 571000 SH SOLE 571000 0 0 Omega Healthcare Investors, Inc. Common 681936100 14336 458616 SH SOLE 458616 0 0 Paratek Pharmaceuticals, Inc. Common 699374302 11744 762581 SH SOLE 762581 0 0 Perrigo Company plc Shares G97822103 3104 37300 SH SOLE 37300 0 0 Pfizer Inc. Common 717081103 37244 1146689 SH SOLE 1146689 0 0 Physicians Realty Trust Common 71943U104 10062 530672 SH SOLE 530672 0 0 Pieris Pharmaceuticals, Inc. Common 720795103 5804 4145958 SH SOLE 4145958 0 0 PRA Health Sciences, Inc. Common 69354M108 5622 102000 SH SOLE 102000 0 0 Puma Biotechnology, Inc. Common 74587V107 7988 260200 SH SOLE 260200 0 0 Quorum Health Corporation Common 74909E106 172 23725 SH SOLE 23725 0 0 Regeneron Pharmaceuticals, Inc. Common 75886F107 68890 187666 SH SOLE 187666 0 0 Retrophin, Inc. Common 761299106 3179 167949 SH SOLE 167949 0 0 The RMR Group Inc. Class A 74967R106 294 7441 SH SOLE 7441 0 0 Sabra Health Care REIT, Inc. Common 78573L106 13455 550990 SH SOLE 550990 0 0 Sage Therapeutics, Inc. Common 78667J108 2757 54000 SH SOLE 54000 0 0 Sanofi Sponsored ADR 80105N105 12334 305000 SH SOLE 305000 0 0 Sarepta Therapeutics, Inc. Common 803607100 12791 466300 SH SOLE 466300 0 0 Senior Housing Properties Trust Shares 81721M109 12239 646554 SH SOLE 646554 0 0 Shire plc Sponsored ADR 82481R106 39428 231413 SH SOLE 231413 0 0 Spark Therapeutics, Inc. Common 84652J103 1213 24300 SH SOLE 24300 0 0 SPDR S&P Biotech ETF ETF 78464A870 10595 179000 SH SOLE 179000 0 0 Tenet Healthcare Corporation Common 88033G407 2441 164500 SH SOLE 164500 0 0 Tetraphase Pharmaceuticals, Inc. Common 88165N105 775 192322 SH SOLE 192322 0 0 Teva Pharmaceutical Industries Ltd. Sponsored ADR 881624209 28600 788958 SH SOLE 788958 0 0 TherapeuticsMD, Inc. Common 88338N107 1080 187100 SH SOLE 187100 0 0 Thermo Fisher Scientific Inc. Common 883556102 19912 141120 SH SOLE 141120 0 0 Ultragenyx Pharmaceutical Inc. Common 90400D108 6215 88400 SH SOLE 88400 0 0 uniQure N.V. Shares N90064101 1350 241021 SH SOLE 241021 0 0 United Therapeutics Corporation Common 91307C102 13353 93100 SH SOLE 93100 0 0 UnitedHealth Group Inc. Common 91324P102 39357 245920 SH SOLE 245920 0 0 Universal Health Services, Inc. Class B 913903100 15614 146780 SH SOLE 146780 0 0 Valeant Pharmaceuticals International, Inc. Common 91911K102 2788 192000 SH SOLE 192000 0 0 Ventas, Inc. Common 92276F100 11003 175991 SH SOLE 175991 0 0 Vertex Pharmaceuticals Incorporated Common 92532F100 76138 1033503 SH SOLE 1033503 0 0 Welltower Inc. 6.50% Preferred Perpetual 95040Q203 12036 200000 SH SOLE 200000 0 0 Welltower Inc. Common 95040Q104 1432 21400 SH SOLE 21400 0 0 Xencor, Inc. Common 98401F105 526 20000 SH SOLE 20000 0 0 Xenon Pharmaceuticals Inc. Common 98420N105 5390 700000 SH SOLE 700000 0 0 Zafgen, Inc. Common 98885E103 42 13307 SH SOLE 13307 0 0 Zimmer Biomet Holdings, Inc. Common 98956P102 10557 102300 SH SOLE 102300 0 0