Chief Compliance Officer

0001104659-16-156805.txt : 20161114 0001104659-16-156805.hdr.sgml : 20161111 20161114144658 ACCESSION NUMBER: 0001104659-16-156805 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20160930 FILED AS OF DATE: 20161114 DATE AS OF CHANGE: 20161114 EFFECTIVENESS DATE: 20161114 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Tekla Capital Management LLC CENTRAL INDEX KEY: 0001300336 IRS NUMBER: 010628853 STATE OF INCORPORATION: DE FISCAL YEAR END: 0930 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-10950 FILM NUMBER: 161993877 BUSINESS ADDRESS: STREET 1: 100 FEDERAL STREET STREET 2: 19TH FLOOR CITY: BOSTON STATE: MA ZIP: 02110 BUSINESS PHONE: 617 772-8500 MAIL ADDRESS: STREET 1: 100 FEDERAL STREET STREET 2: 19TH FLOOR CITY: BOSTON STATE: MA ZIP: 02110 FORMER COMPANY: FORMER CONFORMED NAME: Hambrecht & Quist Capital Management LLC DATE OF NAME CHANGE: 20040811 13F-HR 1 primary_doc.xml 13F-HR LIVE 0001300336 XXXXXXXX 09-30-2016 09-30-2016 false Tekla Capital Management LLC

100 FEDERAL STREET 19TH FLOOR BOSTON MA 02110

13F HOLDINGS REPORT 028-10950 N Laura Woodward Chief Compliance Officer 617-772-8500 /s/ Laura Woodward Boston MA 11-14-2016 0 142 2600463 false INFORMATION TABLE 2 a16-19682_1informationtable.xml INFORMATION TABLE Abbott Laboratories Common 002824100 58301 1378600 SH SOLE 1378600 0 0 AbbVie Inc. Common 00287Y109 10 156 SH SOLE 156 0 0 Acadia Healthcare Company. Inc. Common 00404A109 1744 35200 SH SOLE 35200 0 0 ACADIA Pharmaceuticals Inc. Common 004225108 3556 111800 SH SOLE 111800 0 0 Accelerate Diagnostics, Inc. Common 00430H102 3271 120000 SH SOLE 120000 0 0 Adaptimmune Theraputics plc Sponsored ADR 00653A107 3993 566368 SH SOLE 566368 0 0 Aegerion Pharmaceuticals, Inc. Note 2.00% 8/15/19 00767EAB8 8572 13000000 PRN SOLE 13000000 0 0 Affimed NV Common N01045108 818 294213 SH SOLE 294213 0 0 Agilent Technologies, Inc. Common 00846U101 21659 459950 SH SOLE 459950 0 0 Akorn, Inc. Common 009728106 3959 145235 SH SOLE 145235 0 0 Alexion Pharmaceuticals, Inc. Common 015351109 93621 764005 SH SOLE 764005 0 0 Alkermes plc Shares G01767105 27369 581944 SH SOLE 581944 0 0 Allergan plc Common G0177J108 99974 434086 SH SOLE 434086 0 0 Allergan plc Preferred Convertible G0177J116 4108 5000 SH SOLE 5000 0 0 Alliqua BioMedical, Inc. Common 019621200 1287 1650000 SH SOLE 1650000 0 0 Allscripts Healthcare Solutions, Inc. Common 01988P108 2286 173600 SH SOLE 173600 0 0 Alnylam Pharmaceuticals, Inc. Common 02043Q107 16538 243995 SH SOLE 243995 0 0 AmerisourceBergen Corporation Common 03073E105 26713 330687 SH SOLE 330687 0 0 Amgen Inc. Common 031162100 53653 321640 SH SOLE 321640 0 0 Amicus Therapeutics, Inc. Common 03152W109 1909 258000 SH SOLE 258000 0 0 ARCA biopharma, Inc. Common 00211Y407 2344 811227 SH SOLE 811227 0 0 Ardelyx, Inc. Common 039697107 9157 707636 SH SOLE 707636 0 0 ARIAD Pharmaceuticals, Inc. Common 04033A100 6872 502000 SH SOLE 502000 0 0 AstraZeneca PLC Sponsored ADR 046353108 15240 463800 SH SOLE 463800 0 0 Auris Medical Holding AG Common H03579101 1340 774504 SH SOLE 774504 0 0 Becton Dickinson and Company Common 075887109 11337 63078 SH SOLE 63078 0 0 BeiGene Ltd. Sponsored ADR 07725L102 3596 116707 SH SOLE 116707 0 0 Bellicum Pharmaceuticals, Inc. Common 079481107 1194 60000 SH SOLE 60000 0 0 Biogen Inc. Common 09062X103 150891 482033 SH SOLE 482033 0 0 BioMarin Pharmaceutical Inc. Common 09061G101 65703 710145 SH SOLE 710145 0 0 bluebird bio, Inc. Common 09609G100 3345 49345 SH SOLE 49345 0 0 Cardinal Health, Inc. Common 14149Y108 11849 152500 SH SOLE 152500 0 0 Celgene Corporation Common 151020104 155132 1484089 SH SOLE 1484089 0 0 Celldex Therapeutics, Inc. Common 15117B103 427 105800 SH SOLE 105800 0 0 Cellectis S.A. Sponsored ADR 15117K103 7471 310250 SH SOLE 310250 0 0 Centene Corporation Common 15135B101 17175 256500 SH SOLE 256500 0 0 Cepheid, Inc. Common 15670R107 17577 333590 SH SOLE 333590 0 0 Charles River Laboratories International, Inc. Common 159864107 9584 115000 SH SOLE 115000 0 0 Chimerix, Inc. Common 16934W106 1711 308892 SH SOLE 308892 0 0 Cidara Therapeutics, Inc. Common 171757107 1517 132472 SH SOLE 132472 0 0 Cigna Corporation Common 125509109 11260 86400 SH SOLE 86400 0 0 Community Health Systems, Inc. Common 203668108 3514 304472 SH SOLE 304472 0 0 CVS Caremark Corporation Common 126650100 36654 411891 SH SOLE 411891 0 0 CytomX Therapeutics, Inc. Common 23284F105 11855 756090 SH SOLE 756090 0 0 DaVita, Inc. Common 23918K108 10644 161100 SH SOLE 161100 0 0 DBV Technologies Sponsored ADR 23306J101 2383 65600 SH SOLE 65600 0 0 Depomed, Inc. Common 249908104 4998 200000 SH SOLE 200000 0 0 Dermira, Inc. Common 24983L104 2794 82600 SH SOLE 82600 0 0 Diplomat Pharmacy, Inc. Common 25456K101 2441 87163 SH SOLE 87163 0 0 Dynavax Technologies Corporation Common 268158201 3620 345050 SH SOLE 345050 0 0 Egalet Corporation Note 5.50% 4/1/20 28226BAB0 5963 7000000 PRN SOLE 7000000 0 0 Eli Lilly & Company Common 532457108 57287 713767 SH SOLE 713767 0 0 Endo International plc Shares G30401106 18428 914548 SH SOLE 914548 0 0 Endologix, Inc. Common 29266S106 9901 773500 SH SOLE 773500 0 0 Epizyme, Inc. Common 29428V104 3936 400000 SH SOLE 400000 0 0 Esperion Therapeutics, Inc. Common 29664W105 1424 102800 SH SOLE 102800 0 0 Exelixis, Inc. Common 30161Q104 7056 551647 SH SOLE 551647 0 0 Flamel Technologies SA Sponsored ADR 338488109 7741 624288 SH SOLE 624288 0 0 Flex Pharma, Inc. Common 33938A105 1910 162124 SH SOLE 162124 0 0 Foamix Pharmaceuticals, Ltd. Shares M46135105 8946 966065 SH SOLE 966065 0 0 Forward Pharma A/S Sponsored ADR 34986J105 2867 136547 SH SOLE 136547 0 0 Galapagos NV Sponsored ADR 36315X101 9553 147738 SH SOLE 147738 0 0 GenMark Diagnostics, Inc. Common 372309104 1102 93349 SH SOLE 93349 0 0 Gilead Sciences, Inc. Common 375558103 210470 2660131 SH SOLE 2660131 0 0 GlaxoSmithKline plc Sponsored ADR 37733W105 15484 359000 SH SOLE 359000 0 0 Global Blood Therapeutics, Inc. Common 37890U108 2881 125000 SH SOLE 125000 0 0 Grifols SA Sponsored ADR 398438408 2651 166000 SH SOLE 166000 0 0 Halozyme Therapeutics, Inc. Common 40637H109 2416 200000 SH SOLE 200000 0 0 HCA Holdings, Inc. Common 40412C101 7237 95684 SH SOLE 95684 0 0 Horizon Pharma plc Shares G4617B105 13596 749900 SH SOLE 749900 0 0 Humana, Inc. Common 444859102 29151 164800 SH SOLE 164800 0 0 ICON plc Shares G4705A100 5571 72000 SH SOLE 72000 0 0 IDEXX Laboratories, Inc. Common 45168D104 14920 132352 SH SOLE 132352 0 0 Illumina, Inc. Common 452327109 44790 246560 SH SOLE 246560 0 0 Immunomedics, Inc. Note 4.75% 2/15/20 452907AK4 3378 4000000 PRN SOLE 4000000 0 0 Impax Laboratories, Inc. Common 45256B101 2947 124335 SH SOLE 124335 0 0 Incyte Corporation Common 45337C102 83019 880461 SH SOLE 880461 0 0 Inotek Pharmaceuticals Corporation Common 45780V102 1714 180762 SH SOLE 180762 0 0 Intellia Therapeutics, Inc. Common 45826J105 1223 71842 SH SOLE 71842 0 0 iShares Nasdaq Biotechnology ETF ETF 464287556 16693 57670 SH SOLE 57670 0 0 Jazz Pharmaceuticals plc Shares G50871105 40260 331411 SH SOLE 331411 0 0 Johnson & Johnson Common 478160104 39847 337312 SH SOLE 337312 0 0 Juno Therapeutics, Inc. Common 48205A109 5462 182000 SH SOLE 182000 0 0 Karyopharm Therapeutics, Inc. Common 48576U106 4868 500324 SH SOLE 500324 0 0 LTC Properties, Inc. Common 502175102 5522 106212 SH SOLE 106212 0 0 Mallinckrodt plc Shares G5785G107 4319 61900 SH SOLE 61900 0 0 McKesson Corporation Common 58155Q103 2501 15000 SH SOLE 15000 0 0 Medical Properties Trust, Inc. Common 58463J304 12395 839217 SH SOLE 839217 0 0 The Medicines Company Common 584688105 21302 564438 SH SOLE 564438 0 0 Medtronic plc Shares G5960L103 53830 623030 SH SOLE 623030 0 0 Merck & Co., Inc. Common 58933Y105 77788 1246397 SH SOLE 1246397 0 0 Merrimack Pharmaceuticals, Inc. Note 4.50% 7/15/20 590328AA8 1879 1485000 PRN SOLE 1485000 0 0 Merrimack Pharmaceuticals, Inc. Common 590328100 1816 286000 SH SOLE 286000 0 0 Merus B.V. Common N5749R100 4355 260000 SH SOLE 260000 0 0 Molina Healthcare, Inc. Common 60855R100 23476 402541 SH SOLE 402541 0 0 Momenta Pharmaceuticals, Inc. Common 60877T100 1797 153700 SH SOLE 153700 0 0 Mylan NV Shares N59465109 43287 1135552 SH SOLE 1135552 0 0 Natera, Inc. Common 632307104 9803 882358 SH SOLE 882358 0 0 Neurocrine Biosciences, Inc. Common 64125C109 33251 656622 SH SOLE 656622 0 0 Nevro Corp. Common 64157F103 2610 25000 SH SOLE 25000 0 0 New Senior Investment Group Inc. Common 648691103 4974 430997 SH SOLE 430997 0 0 Novartis AG Sponsored ADR 66987V109 19645 248800 SH SOLE 248800 0 0 Novavax, Inc. Common 670002104 1188 571000 SH SOLE 571000 0 0 Omega Healthcare Investors, Inc. Common 681936100 14645 413116 SH SOLE 413116 0 0 Paratek Pharmaceuticals, Inc. Common 699374302 9921 762581 SH SOLE 762581 0 0 Perrigo Company plc Shares G97822103 3444 37300 SH SOLE 37300 0 0 Pfizer Inc. Common 717081103 38838 1146689 SH SOLE 1146689 0 0 Physicians Realty Trust Common 71943U104 11431 530672 SH SOLE 530672 0 0 Pieris Pharmaceuticals, Inc. Common 720795103 7587 4145958 SH SOLE 4145958 0 0 PRA Health Sciences, Inc. Common 69354M108 5764 102000 SH SOLE 102000 0 0 Puma Biotechnology, Inc. Common 74587V107 17446 260200 SH SOLE 260200 0 0 Quorum Health Corporation Common 74909E106 477 76118 SH SOLE 76118 0 0 Regeneron Pharmaceuticals, Inc. Common 75886F107 62018 154266 SH SOLE 154266 0 0 Retrophin, Inc. Common 761299106 7384 329949 SH SOLE 329949 0 0 Revance Therapeutics, Inc. Common 761330109 1216 75000 SH SOLE 75000 0 0 The RMR Group Inc. Class A 74967R106 282 7441 SH SOLE 7441 0 0 Sabra Health Care REIT, Inc. Common 78573L106 11487 456190 SH SOLE 456190 0 0 Sage Therapeutics, Inc. Common 78667J108 6760 146800 SH SOLE 146800 0 0 Sanofi Sponsored ADR 80105N105 11648 305000 SH SOLE 305000 0 0 Sarepta Therapeutics, Inc. Common 803607100 13148 214100 SH SOLE 214100 0 0 Senior Housing Properties Trust Shares 81721M109 13059 575054 SH SOLE 575054 0 0 Shire plc Sponsored ADR 82481R106 44862 231413 SH SOLE 231413 0 0 Supernus Pharmaceuticals, Inc. Note 7.50% 5/1/19 868459AB4 9334 2000000 PRN SOLE 2000000 0 0 Tenet Healthcare Corporation Common 88033G407 3728 164500 SH SOLE 164500 0 0 Tetraphase Pharmaceuticals Inc. Common 88165N105 737 192322 SH SOLE 192322 0 0 Teva Pharmaceutical Industries Limited Sponsored ADR 881624209 36300 788958 SH SOLE 788958 0 0 TherapeuticsMD, Inc. Common 88338N107 2091 307000 SH SOLE 307000 0 0 Thermo Fisher Scientific Inc. Common 883556102 13742 86395 SH SOLE 86395 0 0 Ultragenyx Pharmaceutical Inc. Common 90400D108 6271 88400 SH SOLE 88400 0 0 UniQure NV Shares N90064101 1844 241021 SH SOLE 241021 0 0 United Therapeutics Corporation Common 91307C102 10993 93100 SH SOLE 93100 0 0 Unitedhealth Group, Inc. Common 91324P102 46354 331100 SH SOLE 331100 0 0 Universal Health Services, Inc. Class B 913903100 16595 134680 SH SOLE 134680 0 0 Valeant Pharmaceuticals International, Inc. Common 91911K102 4714 192000 SH SOLE 192000 0 0 Ventas, Inc. Common 92276F100 10770 152491 SH SOLE 152491 0 0 Vertex Pharmaceuticals Incorporated Common 92532F100 90132 1033503 SH SOLE 1033503 0 0 Vitae Pharmaceuticals, Inc. Common 92847N103 5230 250000 SH SOLE 250000 0 0 Welltower, Inc. Preferred Convertible 95040Q203 13310 200000 SH SOLE 200000 0 0 Xencor, Inc. Common 98401F105 490 20000 SH SOLE 20000 0 0 Xenon Pharmaceuticals Inc. Common 98420N105 5670 700000 SH SOLE 700000 0 0 Zafgen, Inc. Common 98885E103 44 13307 SH SOLE 13307 0 0 Zimmer Biomet Holdings, Inc. Common 98956P102 13301 102300 SH SOLE 102300 0 0