Chief Compliance Officer

0001104659-16-139243.txt : 20160812 0001104659-16-139243.hdr.sgml : 20160812 20160812121622 ACCESSION NUMBER: 0001104659-16-139243 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20160630 FILED AS OF DATE: 20160812 DATE AS OF CHANGE: 20160812 EFFECTIVENESS DATE: 20160812 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Tekla Capital Management LLC CENTRAL INDEX KEY: 0001300336 IRS NUMBER: 010628853 STATE OF INCORPORATION: DE FISCAL YEAR END: 0930 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-10950 FILM NUMBER: 161827165 BUSINESS ADDRESS: STREET 1: 100 FEDERAL STREET STREET 2: 19TH FLOOR CITY: BOSTON STATE: MA ZIP: 02110 BUSINESS PHONE: 617 772-8500 MAIL ADDRESS: STREET 1: 100 FEDERAL STREET STREET 2: 19TH FLOOR CITY: BOSTON STATE: MA ZIP: 02110 FORMER COMPANY: FORMER CONFORMED NAME: Hambrecht & Quist Capital Management LLC DATE OF NAME CHANGE: 20040811 13F-HR 1 primary_doc.xml 13F-HR LIVE 0001300336 XXXXXXXX 06-30-2016 06-30-2016 false Tekla Capital Management LLC

100 FEDERAL STREET 19TH FLOOR BOSTON MA 02110

13F HOLDINGS REPORT 028-10950 N Laura Woodward Chief Compliance Officer 617-772-8500 /s/ Laura Woodward Boston MA 08-12-2016 0 156 2445918 false INFORMATION TABLE 2 a16-14443_1informationtable.xml INFORMATION TABLE Abbott Laboratories Common 002824100 37482 953500 SH SOLE 953500 0 0 Abbott Laboratories Common 002824100 4866 123800 SH Call SOLE 247600 0 0 AbbVie Inc. Common 00287Y109 10 156 SH SOLE 156 0 0 ACADIA Pharmaceuticals Inc. Common 004225108 11802 363585 SH SOLE 363585 0 0 Accelerate Diagnostics, Inc. Common 00430H102 3808 264625 SH SOLE 264625 0 0 Adaptimmune Therapeutics plc Sponsored ADR 00653A107 2420 296934 SH SOLE 296934 0 0 Aegerion Pharmaceuticals, Inc. Note 2.00% 8/15/19 00767EAB8 7410 13000000 PRN SOLE 13000000 0 0 Affimed NV Common N01045108 730 294213 SH SOLE 294213 0 0 Agilent Technologies, Inc. Common 00846U101 21978 495450 SH SOLE 495450 0 0 Akorn, Inc. Common 009728106 6986 245235 SH SOLE 245235 0 0 Alexion Pharmaceuticals, Inc. Common 015351109 79608 681805 SH SOLE 681805 0 0 Alkermes plc Shares G01767105 29988 693844 SH SOLE 693844 0 0 Alkermes plc Common G01767105 4836 111900 SH Call SOLE 111900 0 0 Allergan plc Common G0177J108 107199 463886 SH SOLE 463886 0 0 Allergan plc Preferred Convertible G0177J116 4168 5000 SH SOLE 5000 0 0 Alliqua BioMedical, Inc. Common 019621200 1848 1650000 SH SOLE 1650000 0 0 Allscripts Healthcare Solutions, Inc. Common 01988P108 2205 173600 SH SOLE 173600 0 0 Alnylam Pharmaceuticals, Inc. Common 02043Q107 13539 243995 SH SOLE 243995 0 0 AmerisourceBergen Corporation Common 03073E105 29864 376500 SH SOLE 376500 0 0 AmerisourceBergen Corporation Common 03073E105 3292 41500 SH Call SOLE 41500 0 0 Amgen Inc. Common 031162100 50474 331740 SH SOLE 331740 0 0 Amgen Inc. Common 031162100 1537 10100 SH Call SOLE 10100 0 0 Amicus Therapeutics, Inc. Common 03152W109 1409 258000 SH SOLE 258000 0 0 ARCA biopharma, Inc. Common 00211Y407 2353 811227 SH SOLE 811227 0 0 Ardelyx, Inc. Common 039697107 12129 1389370 SH SOLE 1389370 0 0 ARIAD Pharmaceuticals Inc. Common 04033A100 3710 502000 SH SOLE 502000 0 0 AstraZeneca PLC Sponsored ADR 046353108 3327 110200 SH Call SOLE 110200 0 0 AstraZeneca PLC Sponsored ADR 046353108 17329 574000 SH SOLE 574000 0 0 Auris Medical Holding AG Common H03579101 3496 834263 SH SOLE 834263 0 0 BeiGene Ltd. Sponsored ADR 07725L102 3478 116707 SH SOLE 116707 0 0 Bellicum Pharmaceuticals, Inc. Common 079481107 778 60000 SH SOLE 60000 0 0 Biogen Inc. Common 09062X103 108948 450533 SH SOLE 450533 0 0 BioMarin Pharmaceutical Inc. Common 09061G101 50869 653845 SH SOLE 653845 0 0 BioMarin Pharmaceutical Inc. Common 09061G101 4489 57700 SH Call SOLE 57700 0 0 bluebird bio, Inc. Common 09609G100 2136 49345 SH SOLE 49345 0 0 Bristol-Myers Squibb Co. Common ADI0M9WV6 6421 87300 SH Put SOLE 87300 0 0 Care Capital Properties, Inc. Common 141624106 2210 84316 SH SOLE 84316 0 0 Celgene Corporation Common 151020104 137963 1398789 SH SOLE 1398789 0 0 Celgene Corporation Common 151020104 3077 31200 SH Call SOLE 31200 0 0 Celldex Therapeutics, Inc. Common 15117B103 464 105800 SH SOLE 105800 0 0 Cellectis S.A. Sponsored ADS 15117K103 8250 310250 SH SOLE 310250 0 0 Centene Corporation Common 15135B101 8564 120000 SH SOLE 120000 0 0 Cepheid, Inc. Common 15670R107 10258 333590 SH SOLE 333590 0 0 Cepheid, Inc. Note 1.25% 2/1/21 15670RAC1 8669 10000000 PRN SOLE 10000000 0 0 Chimerix, Inc. Common 16934W106 1214 308892 SH SOLE 308892 0 0 Cidara Therapeutics, Inc. Common 171757107 1366 132472 SH SOLE 132472 0 0 Community Health Systems, Inc. Common 203668108 3669 304472 SH SOLE 304472 0 0 Corsicanto Ltd Note 3.50% 1/15/32 220480AB3 14930 14700000 PRN SOLE 14700000 0 0 CVS Caremark Corporation Common 126650100 21435 223891 SH SOLE 223891 0 0 Cynapsus Therapeutics, Inc. Common 23257Y859 7708 460207 SH SOLE 460207 0 0 CytomX Therapeutics, Inc. Common 23284F105 7723 756090 SH SOLE 756090 0 0 DBV Technologies S.A. Sponsored ADR 23306J101 2140 65600 SH SOLE 65600 0 0 Depomed Inc. Common 249908104 3924 200000 SH SOLE 200000 0 0 Dynavax Technologies Corporation Common 268158201 5031 345050 SH SOLE 345050 0 0 Egalet Corporation Note 5.50% 4/1/20 28226BAB0 5281 7000000 PRN SOLE 7000000 0 0 Eli Lilly and Company Common 532457108 39577 502567 SH SOLE 502567 0 0 Endo International plc Shares G30401106 4464 286348 SH SOLE 286348 0 0 Endologix Inc. Common 29266S106 6865 551000 SH SOLE 551000 0 0 Epizyme, Inc. Common 29428V104 4096 400000 SH SOLE 400000 0 0 Esperion Therapeutics, Inc. Common 29664W105 1016 102800 SH SOLE 102800 0 0 Exelixis, Inc. Common 30161Q104 10976 1405420 SH SOLE 1405420 0 0 Flamel Technologies SA Sponsored ADR 338488109 6705 624288 SH SOLE 624288 0 0 Flex Pharm, Inc. Common 33938A105 1655 162124 SH SOLE 162124 0 0 Foamix Pharmaceuticals Ltd. Shares M46135105 6135 966065 SH SOLE 966065 0 0 Forward Pharma A/S Sponsored ADR 34986J105 2481 136547 SH SOLE 136547 0 0 Galapagos NV Sponsored ADR 36315X101 8195 147738 SH SOLE 147738 0 0 GenMark Diagnostics, Inc. Common 372309104 812 93349 SH SOLE 93349 0 0 Gilead Sciences, Inc. Common 375558103 209529 2511731 SH SOLE 2511731 0 0 Gilead Sciences, Inc. Common 375558103 4788 57400 SH Call SOLE 57400 0 0 GlaxoSmithKline plc Common 37733W105 3259 75200 SH Call SOLE 75200 0 0 GlaxoSmithKline plc Sponsored ADR 37733W105 18818 434200 SH SOLE 434200 0 0 Global Blood Therapeutics, Inc. Common 37890U108 2074 125000 SH SOLE 125000 0 0 Grifols SA Sponsored ADR 398438408 2767 166000 SH SOLE 166000 0 0 Halozyme Therapeutics, Inc. Common 40637H109 1726 200000 SH SOLE 200000 0 0 HCA Holdings, Inc. Common 40412C101 25798 334998 SH SOLE 334998 0 0 Heron Therapeutics, Inc. Common 427746102 8886 492303 SH SOLE 492303 0 0 Horizon Pharma plc Shares G4617B105 12351 749900 SH SOLE 749900 0 0 Humana Inc. Common 444859102 23258 129300 SH SOLE 129300 0 0 ICON plc Shares G4705A100 5041 72000 SH SOLE 72000 0 0 IDEXX Laboratories, Inc. Common 45168D104 12290 132352 SH SOLE 132352 0 0 Illumina Inc. Common 452327109 52132 371364 SH SOLE 371364 0 0 Immunomedics, Inc. Note 4.75% 2/15/20 452907AK4 2715 4000000 PRN SOLE 4000000 0 0 Impax Laboratories, Inc. Common 45256B101 3583 124335 SH SOLE 124335 0 0 Incyte Corporation Common 45337C102 70419 880461 SH SOLE 880461 0 0 Inotek Pharmaceuticals Corporation Common 45780V102 1345 180762 SH SOLE 180762 0 0 Intellia Therapeutics, Inc. Common 45826J105 1854 86842 SH SOLE 86842 0 0 Intra-Cellular Therapies, Inc. Common 46116X101 7290 187800 SH SOLE 187800 0 0 Ishares Nasdaq Biotechnology ETF ETF 464287556 14841 57670 SH SOLE 57670 0 0 Jazz Pharmaceuticals plc Shares G50871105 22108 156451 SH SOLE 156451 0 0 Johnson & Johnson Common 478160104 40916 337312 SH SOLE 337312 0 0 Juno Therapeutics, Inc. Common 48205A109 6996 182000 SH SOLE 182000 0 0 Karyopharm Therapeutics, Inc. Common 48576U106 3357 500324 SH SOLE 500324 0 0 Kite Pharma, Inc. Common 49803L109 2050 41000 SH SOLE 41000 0 0 LTC Properties Inc. Common 502175102 5494 106212 SH SOLE 106212 0 0 Mallinckrodt plc Shares G5785G107 13609 223900 SH SOLE 223900 0 0 McKesson Corporation Common 58155Q103 2800 15000 SH SOLE 15000 0 0 Medical Properties Trust, Inc. Common 58463J304 13999 920393 SH SOLE 920393 0 0 The Medicines Company Common 584668105 9403 279600 SH Call SOLE 279600 0 0 The Medicines Company Common 584688105 23684 704238 SH SOLE 704238 0 0 Medivation, Inc. Common 58501N101 15475 256638 SH SOLE 256638 0 0 Medivation, Inc. Common 58501N101 3618 60000 SH Call SOLE 60000 0 0 Medtronic plc Shares G5960L103 59325 683704 SH SOLE 683704 0 0 Merck & Co., Inc. Common 58933Y105 45950 797597 SH SOLE 797597 0 0 Merrimack Pharmaceuticals, Inc. Note 4.50% 7/15/20 590328AA8 1654 1485000 PRN SOLE 1485000 0 0 Merrimack Pharmaceuticals, Inc. Common 590328100 1542 286000 SH SOLE 286000 0 0 Merus B.V. Common N5749R100 2113 260000 SH SOLE 260000 0 0 Molina Healthcare, Inc. Common 60855R100 26841 537901 SH SOLE 537901 0 0 Momenta Pharmaceuticals, Inc. Common 60877T100 1660 153700 SH SOLE 153700 0 0 Mylan NV Shares N59465109 31243 722552 SH SOLE 722552 0 0 Mylan NV Shares N59465109 4523 104600 SH Call SOLE 104600 0 0 Natera, Inc. Common 632307104 10646 882358 SH SOLE 882358 0 0 Neurocrine Biosciences, Inc. Common 64125C109 34861 767022 SH SOLE 767022 0 0 Neurocrine Biosciences, Inc. Common 64125C109 5018 110400 SH Call SOLE 110400 0 0 Nevro Corp. Common 64157F103 3673 49800 SH SOLE 49800 0 0 Novartis AG Sponsored ADR 66987V109 14035 170100 SH SOLE 170100 0 0 Novavax, Inc. Common 670002104 2603 358000 SH SOLE 358000 0 0 Omega Healthcare Investors Inc. Common 681936100 14025 413116 SH SOLE 413116 0 0 Paratek Pharmaceuticals, Inc. Common 699374302 10608 762581 SH SOLE 762581 0 0 Perrigo Company plc Shares G97822103 3382 37300 SH SOLE 37300 0 0 Pfizer Inc. Common 717081103 52227 1483291 SH SOLE 1483291 0 0 Physicians Realty Trust Common 71943U104 11149 530672 SH SOLE 530672 0 0 Pieris Pharmaceuticals, Inc. Common 720795103 6196 3848191 SH SOLE 3848191 0 0 PRA Health Sciences, Inc. Common 69354M108 4260 102000 SH SOLE 102000 0 0 Puma Biotechnology, Inc. Common 74587V107 7751 260200 SH SOLE 260200 0 0 Quorum Health Corp. Common 74909E106 815 76118 SH SOLE 76118 0 0 Regeneron Pharmaceuticals, Inc. Common 75886F107 53874 154266 SH SOLE 154266 0 0 Retrophin, Inc. Common 761299106 5876 329949 SH SOLE 329949 0 0 Revance Therapeutics, Inc. Common 761330109 1020 75000 SH SOLE 75000 0 0 The RMR Group Inc., Class A Class A 74967R106 230 7441 SH SOLE 7441 0 0 Sabra Health Care REIT Inc. Common 78573L106 9413 456190 SH SOLE 456190 0 0 Sage Therapeutics, Inc. Common 78667J108 4423 146800 SH SOLE 146800 0 0 Sagent Pharmaceuticals, Inc. Common 786692103 4294 286650 SH SOLE 286650 0 0 Sanofi Sponsored ADR 80105N105 12764 305000 SH SOLE 305000 0 0 Senior Housing Properties Trust Shares 81721M109 13967 670504 SH SOLE 670504 0 0 Shire plc Sponsored ADR 82481R106 37131 201713 SH SOLE 201713 0 0 SPDR S&P Biotech ETF S&P Biotech 78464A870 15902 294000 SH SOLE 294000 0 0 St. Jude Medical, Inc. Common 790849103 12387 158805 SH SOLE 158805 0 0 Supernus Pharmaceuticals, Inc. Note 7.50% 5/1/19 868459AB4 7688 2000000 PRN SOLE 2000000 0 0 Tenet Healthcare Corporation Common 88033G407 4547 164500 SH SOLE 164500 0 0 Tetraphase Pharmaceuticals Inc. Common 88165N105 827 192322 SH SOLE 192322 0 0 Teva Pharmaceutical Industries Ltd. ADR 881624209 33752 671958 SH SOLE 671958 0 0 Thermo Fisher Scientific Inc. Common 883556102 12766 86395 SH SOLE 86395 0 0 Ultragenyx Pharmaceutical Inc. Common 90400D108 4324 88400 SH SOLE 88400 0 0 UniQure NV Shares N90064101 1776 241021 SH SOLE 241021 0 0 United Therapeutics Corporation Common 91307C102 9861 93100 SH SOLE 93100 0 0 UnitedHealth Group, Inc. Common 91324P102 46751 331100 SH SOLE 331100 0 0 Universal Health Services, Inc. Class B 913903100 18061 134680 SH SOLE 134680 0 0 Valeant Pharmaceuticals International, Inc. Common 91911K102 3867 192000 SH SOLE 192000 0 0 Ventas, Inc. Common 92276F100 11104 152491 SH SOLE 152491 0 0 Vertex Pharmaceuticals Incorporated Common 92532F100 88902 1033503 SH SOLE 1033503 0 0 Welltower, Inc. Preferred Convertible 95040Q203 13560 200000 SH SOLE 200000 0 0 Wright Medical Group NV Ordinary Shares N96617118 6999 402950 SH SOLE 402950 0 0 Wright Medical Group NV Ordinary Shares N96617118 2936 169000 SH Call SOLE 169000 0 0 Xencor, Inc. Common 98401F105 380 20000 SH SOLE 20000 0 0 Zafgen, Inc. Common 98885E103 80 13307 SH SOLE 13307 0 0 Zimmer Biomet Holdings, Inc. Common 98956P102 12315 102300 SH SOLE 102300 0 0