Chief Compliance Officer

0001104659-16-119071.txt : 20160509 0001104659-16-119071.hdr.sgml : 20160509 20160509111340 ACCESSION NUMBER: 0001104659-16-119071 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20160331 FILED AS OF DATE: 20160509 DATE AS OF CHANGE: 20160509 EFFECTIVENESS DATE: 20160509 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Tekla Capital Management LLC CENTRAL INDEX KEY: 0001300336 IRS NUMBER: 010628853 STATE OF INCORPORATION: DE FISCAL YEAR END: 0930 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-10950 FILM NUMBER: 161630415 BUSINESS ADDRESS: STREET 1: 100 FEDERAL STREET STREET 2: 19TH FLOOR CITY: BOSTON STATE: MA ZIP: 02110 BUSINESS PHONE: 617 772-8500 MAIL ADDRESS: STREET 1: 100 FEDERAL STREET STREET 2: 19TH FLOOR CITY: BOSTON STATE: MA ZIP: 02110 FORMER COMPANY: FORMER CONFORMED NAME: Hambrecht & Quist Capital Management LLC DATE OF NAME CHANGE: 20040811 13F-HR 1 primary_doc.xml 13F-HR LIVE 0001300336 XXXXXXXX 03-31-2016 03-31-2016 false Tekla Capital Management LLC

100 FEDERAL STREET 19TH FLOOR BOSTON MA 02110

13F HOLDINGS REPORT 028-10950 N Laura Woodward Chief Compliance Officer 617-772-8500 /s/ Laura Woodward Boston MA 05-09-2016 0 140 2351367 false INFORMATION TABLE 2 a16-8263_1informationtable.xml INFORMATION TABLE AbbVie Inc. Common 00287Y109 9 156 SH SOLE 156 0 0 ACADIA Pharmaceuticals Inc. Common 004225108 20000 715299 SH SOLE 715299 0 0 Accelerate Diagnostics, Inc. Common 00430H102 3803 264625 SH SOLE 264625 0 0 Adaptimmune Therapeutics plc Sponsored ADR 00653A107 2414 296934 SH SOLE 296934 0 0 Aegerion Pharmaceuticals, Inc. Note 2.00% 8/15/19 00767EAB8 6606 13000000 PRN SOLE 13000000 0 0 Affimed NV Common N01045108 1100 294213 SH SOLE 294213 0 0 Agilent Technologies, Inc. Common 00846U101 28447 713850 SH SOLE 713850 0 0 Akorn, Inc. Common 009728106 5770 245235 SH SOLE 245235 0 0 Alexion Pharmaceuticals, Inc. Common 015351109 88656 636805 SH SOLE 636805 0 0 Alkermes plc Shares G01767105 19897 581944 SH SOLE 581944 0 0 Allergan plc Shares G0177J108 109781 409586 SH SOLE 409586 0 0 Allergan plc Preferred Convertible G0177J116 4596 5000 SH SOLE 5000 0 0 Alliqua BioMedical, Inc. Common 019621200 1353 1650000 SH SOLE 1650000 0 0 Allscripts Healthcare Solutions, Inc. Common 01988P108 2293 173600 SH SOLE 173600 0 0 Alnylam Pharmaceuticals, Inc. Common 02043Q107 8631 137495 SH SOLE 137495 0 0 Amgen Inc. Common 031162100 48223 321640 SH SOLE 321640 0 0 Amicus Therapeutics, Inc. Common 03152W109 2180 258000 SH SOLE 258000 0 0 Anacor Pharmaceuticals, Inc. Common 032420101 5882 110038 SH SOLE 110038 0 0 ARCA biopharma, Inc. Common 00211Y407 2783 811227 SH SOLE 811227 0 0 Ardelyx, Inc. Common 039697107 10795 1389370 SH SOLE 1389370 0 0 AstraZeneca PLC Sponsored ADR 046353108 10019 355800 SH SOLE 355800 0 0 Auris Medical Holding AG Common H03579101 3037 834263 SH SOLE 834263 0 0 Baxter International Inc. Common 071813109 13129 319600 SH SOLE 319600 0 0 BeiGene Ltd Sponsored ADR 07725L102 3421 116707 SH SOLE 116707 0 0 Bellicum Pharmaceuticals, Inc. Common 079481107 561 60000 SH SOLE 60000 0 0 Biogen Inc. Common 09062X103 117283 450533 SH SOLE 450533 0 0 BioMarin Pharmaceutical Inc. Common 09061G101 49170 596145 SH SOLE 596145 0 0 bluebird bio, Inc. Common 09609G100 2097 49345 SH SOLE 49345 0 0 Bristol-Myers Squibb Co. Common 110122108 12942 202600 SH SOLE 202600 0 0 Care Capital Properties, Inc. Common 141624106 2263 84316 SH SOLE 84316 0 0 Celator Pharmaceuticals, Inc. Common 15089R102 2603 236000 SH SOLE 236000 0 0 Celgene Corporation Common 151020104 174881 1747234 SH SOLE 1747234 0 0 Celldex Therapeutics, Inc. Common 15117B103 400 105800 SH SOLE 105800 0 0 Cellectis S.A. Sponsored ADS 15117K103 8532 310250 SH SOLE 310250 0 0 Centene Corporation Common 15135B101 7388 120000 SH SOLE 120000 0 0 Cepheid, Inc. Common 15670R107 11129 333590 SH SOLE 333590 0 0 Cepheid, Inc. Note 1.25% 2/1/21 15670RAC1 8906 10000000 PRN SOLE 10000000 0 0 Chimerix, Inc. Common 16934W106 1578 308892 SH SOLE 308892 0 0 Cidara Therapeutics, Inc. Common 171757107 921 72500 SH SOLE 72500 0 0 Community Health Systems, Inc. Common 203668108 5636 304472 SH SOLE 304472 0 0 Corsicanto Ltd Note 3.50% 1/15/32 220480AB3 11714 14700000 PRN SOLE 14700000 0 0 Cynapsus Therapeutics, Inc. Common 23257Y859 2147 180407 SH SOLE 180407 0 0 CytomX Therapeutics, Inc. Common 23284F105 4232 328059 SH SOLE 328059 0 0 DBV Technologies S.A. Sponsored ADR 23306J101 2135 65600 SH SOLE 65600 0 0 Depomed, Inc. Common 249908104 2786 200000 SH SOLE 200000 0 0 Dynavax Technologies Corporation Common 268158201 4636 240950 SH SOLE 240950 0 0 Eli Lilly & Co Common 532457108 30040 417167 SH SOLE 417167 0 0 Endo International plc Shares G30401106 8061 286348 SH SOLE 286348 0 0 Endologix Inc. Common 29266S106 4606 551000 SH SOLE 551000 0 0 Epizyme, Inc. Common 29428V104 4848 400000 SH SOLE 400000 0 0 Esperion Therapeutics, Inc. Common 29664W105 1738 102800 SH SOLE 102800 0 0 Exelixis, Inc. Common 30161Q104 5622 1405420 SH SOLE 1405420 0 0 Flamel Technologies SA Sponsored ADR 338488109 6892 624288 SH SOLE 624288 0 0 Flex Pharma, Inc. Common 33938A105 2332 212600 SH SOLE 212600 0 0 Foamix Pharmaceuticals Ltd. Shares M46135105 6299 966065 SH SOLE 966065 0 0 Forward Pharma A/S Sponsored ADR 34986J105 2321 136547 SH SOLE 136547 0 0 Galapagos NV Sponsored ADR 36315X101 836 20000 SH SOLE 20000 0 0 GenMark Diagnostics, Inc. Common 372309104 492 93349 SH SOLE 93349 0 0 Gilead Sciences, Inc. Common 375558103 214147 2331231 SH SOLE 2331231 0 0 GlaxoSmithKline plc Sponsored ADR 37733W105 11557 285000 SH SOLE 285000 0 0 Grifols SA Sponsored ADR 398438408 2568 166000 SH SOLE 166000 0 0 Halozyme Therapeutics, Inc. Common 40637H109 1894 200000 SH SOLE 200000 0 0 HCA Holdings, Inc. Common 40412C101 26147 334998 SH SOLE 334998 0 0 Healthcare Realty Trust, Inc. Common 421946104 5783 187224 SH SOLE 187224 0 0 Healthcare Trust of America, Inc. Common 42225P501 5238 178033 SH SOLE 178033 0 0 Heron Therapeutics, Inc. Common 427746102 4159 219000 SH SOLE 219000 0 0 Horizon Pharma plc Shares G4617B105 12426 749900 SH SOLE 749900 0 0 Humana, Inc. Common 444859102 23655 129300 SH SOLE 129300 0 0 ICON plc Shares G4705A100 8629 114900 SH SOLE 114900 0 0 IDEXX Laboratories, Inc. Common 45168D104 10366 132352 SH SOLE 132352 0 0 Illumina, Inc. Common 452327109 56554 348864 SH SOLE 348864 0 0 Immunomedics, Inc. Note 4.75% 2/15/20 452907AK4 2810 4000000 PRN SOLE 4000000 0 0 Impax Laboratories, Inc. Common 45256B101 3981 124335 SH SOLE 124335 0 0 Incyte Corporation Common 45337C102 69315 956461 SH SOLE 956461 0 0 Inotek Pharmaceuticals Corporation Common 45780V102 3607 487392 SH SOLE 487392 0 0 Insmed Incorporated Common 457669307 2263 178600 SH SOLE 178600 0 0 Intra-Cellular Therapies, Inc. Common 46116X101 5221 187800 SH SOLE 187800 0 0 iShares Nasdaq Biotechnology ETF ETF 464287556 15041 57670 SH SOLE 57670 0 0 Jazz Pharmaceuticals plc Shares G50871105 23380 179091 SH SOLE 179091 0 0 Johnson & Johnson Common 478160104 40585 375088 SH SOLE 375088 0 0 Juno Therapeutics, Inc. Common 48205A109 6932 182000 SH SOLE 182000 0 0 Karyopharm Therapeutics, Inc. Common 48576U106 4463 500324 SH SOLE 500324 0 0 Kite Pharma, Inc. Common 49803L109 1882 41000 SH SOLE 41000 0 0 Lexicon Pharmaceuticals, Inc. Common 528872302 2362 197641 SH SOLE 197641 0 0 LTC Properties Inc. Common 502175102 10705 236618 SH SOLE 236618 0 0 Mallinckrodt plc Shares G5785G107 13721 223900 SH SOLE 223900 0 0 McKesson Corporation Common 58155Q103 13030 82862 SH SOLE 82862 0 0 Medical Properties Trust, Inc. Common 58463J304 20301 1564060 SH SOLE 1564060 0 0 Medivation, Inc. Common 58501N101 30682 667300 SH SOLE 667300 0 0 Medtronic plc Shares G5960L103 41783 557104 SH SOLE 557104 0 0 Merck & Co., Inc. Common 58933Y105 36037 681097 SH SOLE 681097 0 0 Merrimack Pharmaceuticals, Inc. Note 4.50% 7/15/20 590328AA8 2205 1485000 PRN SOLE 1485000 0 0 Merrimack Pharmaceuticals, Inc. Common 590328100 4770 569894 SH SOLE 569894 0 0 Molina Healthcare, Inc. Common 60855R100 22436 347901 SH SOLE 347901 0 0 Momenta Pharmaceuticals, Inc. Common 60877T100 1420 153700 SH SOLE 153700 0 0 Mylan NV Shares Euro N59465109 28642 617952 SH SOLE 617952 0 0 Natera, Inc. Common 632307104 8400 882358 SH SOLE 882358 0 0 Neurocrine Biosciences, Inc. Common 64125C109 12318 311460 SH SOLE 311460 0 0 Nevro Corp. Common 64157F103 2802 49800 SH SOLE 49800 0 0 Novartis AG Sponsored ADR 66987V109 6715 92700 SH SOLE 92700 0 0 Novavax, Inc. Common 670002104 1847 358000 SH SOLE 358000 0 0 Novo Nordisk A/S ADR 670100205 15964 294600 SH SOLE 294600 0 0 Omega Healthcare Investors Inc. Common 681936100 14583 413116 SH SOLE 413116 0 0 Paratek Pharmaceuticals, Inc. Common 699374302 11568 762581 SH SOLE 762581 0 0 Perrigo Company plc Shares G97822103 4772 37300 SH SOLE 37300 0 0 Pfizer, Inc. Common 717081103 53708 1812011 SH SOLE 1812011 0 0 Physicians Realty Trust Common 71943U104 22868 1230772 SH SOLE 1230772 0 0 Pieris Pharmaceuticals, Inc. Common 720795103 7312 3848191 SH SOLE 3848191 0 0 Puma Biotechnology, Inc. Common 74587V107 7642 260200 SH SOLE 260200 0 0 Regeneron Pharmaceuticals, Inc. Common 75886F107 55604 154266 SH SOLE 154266 0 0 Retrophin, Inc. Common 761299106 4507 329949 SH SOLE 329949 0 0 Revance Therapeutics, Inc. Common 761330109 786 45000 SH SOLE 45000 0 0 Sabra Health Care REIT Inc. Common 78573L106 9165 456190 SH SOLE 456190 0 0 Sage Therapeutics, Inc. Common 78667J108 4706 146800 SH SOLE 146800 0 0 Sagent Pharmaceuticals, Inc. Common 786692103 3489 286650 SH SOLE 286650 0 0 Sanofi Sponsored ADR 80105N105 12249 305000 SH SOLE 305000 0 0 Senior Housing Properties Trust Shares 81721M109 11995 670504 SH SOLE 670504 0 0 Shire plc Sponsored ADR 82481R106 34674 201713 SH SOLE 201713 0 0 SPDR S&P Biotech ETF S&P Biotech 78464A870 15188 294000 SH SOLE 294000 0 0 St. Jude Medical, Inc. Common 790849103 14070 255810 SH SOLE 255810 0 0 Stryker Corporation Common 863667101 13298 123940 SH SOLE 123940 0 0 Supernus Pharmaceuticals, Inc. Note 7.50% 5/1/19 868459AB4 6026 2000000 PRN SOLE 2000000 0 0 Tenet Healthcare Corporation Common 88033G407 4759 164500 SH SOLE 164500 0 0 Tetraphase Pharmaceuticals Inc. Common 88165N105 890 192322 SH SOLE 192322 0 0 Teva Pharmaceutical Industries Ltd. ADR 881624209 35956 671958 SH SOLE 671958 0 0 The Medicines Company Common 584688105 17932 564438 SH SOLE 564438 0 0 The RMR Group Inc., Class A Common 74967R106 186 7441 SH SOLE 7441 0 0 Thermo Fisher Scientific Inc. Common 883556102 12233 86395 SH SOLE 86395 0 0 Ultragenyx Pharmaceutical Inc. Common 90400D108 5597 88400 SH SOLE 88400 0 0 UniQure NV Shares N90064101 2863 241021 SH SOLE 241021 0 0 United Therapeutics Corporation Common 91307C102 10374 93100 SH SOLE 93100 0 0 UnitedHealth Group, Inc. Common 91324P102 52733 409100 SH SOLE 409100 0 0 Universal Health Services, Inc. Common 913903100 16797 134680 SH SOLE 134680 0 0 Valeant Pharmaceuticals International, Inc. Common 91911K102 4155 158000 SH SOLE 158000 0 0 Ventas, Inc. Common 92276F100 23249 369266 SH SOLE 369266 0 0 Vertex Pharmaceuticals Incorporated Common 92532F100 82153 1033503 SH SOLE 1033503 0 0 Welltower, Inc. Preferred 95040Q203 12420 200000 SH SOLE 200000 0 0 Xencor, Inc. Common 98401F105 268 20000 SH SOLE 20000 0 0 Zafgen, Inc. Common 98885E103 89 13307 SH SOLE 13307 0 0 Zimmer Biomet Holdings, Inc. Common 98956P102 10908 102300 SH SOLE 102300 0 0