<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0204</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2011-12-14</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001528129</issuerCik>
        <issuerName>Laredo Petroleum Holdings, Inc.</issuerName>
        <issuerTradingSymbol>LPI</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001227704</rptOwnerCik>
            <rptOwnerName>WOLF DONALD D</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>15 W. SIXTH STREET, SUITE 1800</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>TULSA</rptOwnerCity>
            <rptOwnerState>OK</rptOwnerState>
            <rptOwnerZipCode>74119</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
                <footnoteId id="F1"/>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>0</value>
                    <footnoteId id="F1"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">The reporting person does not hold securities of the Issuer. The reporting person currently holds units in Laredo Petroleum, LLC, the Issuer's predecessor. In connection with a corporate reorganization, which will involve Laredo  Petroleum, LLC merging with the Issuer, with the Issuer being the surviving entity, and will be completed on or prior to the closing of the Issuer's initial public offering described in the prospectus dated November 28, 2011, the reporting person will receive common stock of the Issuer in exchange for his vested and unvested units in Laredo Petroleum, LLC.</footnote>
    </footnotes>

    <remarks>Exhibit 24 - Power of Attorney</remarks>

    <ownerSignature>
        <signatureName>/s/ Kenneth E. Dornblaser, as attorney-in-fact for Donald D. Wolf</signatureName>
        <signatureDate>2011-12-14</signatureDate>
    </ownerSignature>
</ownershipDocument>
