0001019056-13-001282.txt : 20131114 0001019056-13-001282.hdr.sgml : 20131114 20131114160018 ACCESSION NUMBER: 0001019056-13-001282 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20130930 FILED AS OF DATE: 20131114 DATE AS OF CHANGE: 20131114 EFFECTIVENESS DATE: 20131114 FILER: COMPANY DATA: COMPANY CONFORMED NAME: PERCEPTIVE ADVISORS LLC CENTRAL INDEX KEY: 0001224962 IRS NUMBER: 000000000 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-10438 FILM NUMBER: 131219844 BUSINESS ADDRESS: STREET 1: 499 PARK AVENUE, 25TH FLOOR CITY: NEW YORK STATE: NY ZIP: 10022 BUSINESS PHONE: 646-205-5340 MAIL ADDRESS: STREET 1: 499 PARK AVENUE, 25TH FLOOR CITY: NEW YORK STATE: NY ZIP: 10022 13F-HR 1 primary_doc.xml 13F-HR LIVE false false false 0001224962 XXXXXXXX 09-30-2013 09-30-2013 false PERCEPTIVE ADVISORS LLC

499 Park Avenue, 25th Floor New York NY 10022

13F HOLDINGS REPORT 028-10438 N Joseph Edelman 646-205-5342 /s/ Joseph Edelman New York NY 11-14-2013 0 107 1196989 INFORMATION TABLE 2 infotable.xml COVIDIEN PLC SHS G2554F113 12873 211245 SH SOLE 211245 0 0 ACADIA PHARMACEUTICALS INC COM 004225108 16774 610615 SH SOLE 610615 0 0 ACASTI PHARMA INC CL A SHS 00430K105 366 154386 SH SOLE 154386 0 0 ACELRX PHARMACEUTICALS INC COM 00444T100 63154 5858400 SH SOLE 5858400 0 0 AEGERION PHARMACEUTICALS INC COM 00767e102 199655 2328341 SH SOLE 2328341 0 0 AETNA INC NEW COM 00817Y108 133 2070 SH SOLE 2070 0 0 ALERE INC COM 01449J105 135 4430 SH SOLE 4430 0 0 AMARIN CORP PLC SPONS ADR NEW 023111206 5489 868500 SH Put SOLE 868500 0 0 AMARIN CORP PLC SPONS ADR NEW 023111206 915 144800 SH Call SOLE 144800 0 0 AMGEN INC COM 031162100 10261 91675 SH SOLE 91675 0 0 AMSURG CORP COM 03232P405 136 3415 SH SOLE 3415 0 0 ANACOR PHARMACEUTICALS INC COM 032420101 10342 973868 SH SOLE 973868 0 0 ANIKA THERAPEUTICS INC COM 035255108 3442 144067 SH SOLE 144067 0 0 ANTHERA PHARMACEUTICALS INC COM NEW 03674U201 1734 431456 SH SOLE 431456 0 0 ARENA PHARMACEUTICALS INC COM 040047102 13481 2558100 SH Put SOLE 2558100 0 0 ARRAY BIOPHARMA INC COM 04269X105 3563 572870 SH SOLE 572870 0 0 ASTEX PHARMACEUTICALS INC COM 04624B103 400 47098 SH SOLE 47098 0 0 ASTRAZENECA PLC SPONSORED ADR 046353108 140 2700 SH SOLE 2700 0 0 ATHERSYS INC COM 04744L106 3526 2150117 SH SOLE 2150117 0 0 AVANIR PHARMACEUTICALS INC CL A NEW 05348P401 816 193000 SH Put SOLE 193000 0 0 AXOGEN INC COM 05463X106 20 4500 SH SOLE 4500 0 0 BIOCRYST PHARMACEUTICALS COM 09058V103 1387 190588 SH SOLE 190588 0 0 CIGNA CORPORATION COM 125509109 17128 222848 SH SOLE 222848 0 0 CVS CAREMARK CORPORATION COM 126650100 131 2300 SH SOLE 2300 0 0 CAPITAL SR LIVING CORP COM 140475104 12988 614089 SH SOLE 614089 0 0 CELL THERAPEUTICS INC COM NPV NEW 2012 150934883 11338 6994673 SH SOLE 6994673 0 0 CELGENE CORP COM 151020104 56201 364619 SH SOLE 364619 0 0 CELLDEX THERAPEUTICS INC NEW COM 15117B103 1711 48300 SH Call SOLE 48300 0 0 CENTENE CORP DEL COM 15135B101 151 2355 SH SOLE 2355 0 0 CHELSEA THERAPEUTICS INTL LT COM 163428105 10220 3418365 SH SOLE 3418365 0 0 CHAMPIONS ONCOLOGY INC RSTD COM 15870p109 2726 1558244 SH SOLE 1558244 0 0 CLOVIS ONCOLOGY INC COM 189464100 11838 194701 SH SOLE 194701 0 0 COMBIMATRIX CORPORATION *W EXP 05/01/201 20009T121 2 5000 SH SOLE 5000 0 0 COMMUNITY HEALTH SYS INC NEW COM 203668108 142 3415 SH SOLE 3415 0 0 CORONADO BIOSCIENCES INC COM 21976U109 3519 501900 SH Put SOLE 501900 0 0 CUTERA INC COM 232109108 110 12400 SH SOLE 12400 0 0 DAVITA HEALTHCARE PARTNERS I COM 23918K108 131 2310 SH SOLE 2310 0 0 DEXCOM INC COM 252131107 2047 72550 SH SOLE 72550 0 0 DYAX CORP COM 26746e103 11613 1692912 SH SOLE 1692912 0 0 ENDOCYTE INC COM 29269A102 2573 193000 SH Put SOLE 193000 0 0 ENDOCYTE INC COM 29269A102 5581 418715 SH SOLE 418715 0 0 EXACT SCIENCES CORP COM 30063P105 20630 1748314 SH SOLE 1748314 0 0 FURIEX PHARMACEUTICALS INC COM 36106P101 220 5000 SH SOLE 5000 0 0 GILEAD SCIENCES INC COM 375558103 54324 864070 SH SOLE 864070 0 0 HANGER INC COM NEW 41043F208 138 4080 SH SOLE 4080 0 0 HEALTHSOUTH CORP COM NEW 421924309 144 4190 SH SOLE 4190 0 0 HEALTH NET INC COM 42222G108 14385 453780 SH SOLE 453780 0 0 HEARTWARE INTL INC COM 422368100 366 5000 SH SOLE 5000 0 0 IMMUNOMEDICS INC COM 452907108 4573 737505 SH SOLE 737505 0 0 INFINITY PHARMACEUTICALS INC COM 45665G303 3402 195155 SH SOLE 195155 0 0 INTERMUNE INC COM 45884X103 4614 300000 SH SOLE 300000 0 0 ISHARES NASDQ BIOTEC ETF 464287556 30350 144800 SH Put SOLE 144800 0 0 ISHARES RUSSELL 2000 ETF 464287655 10288 96500 SH Put SOLE 96500 0 0 ISIS PHARMACEUTICALS INC COM 464330109 7238 192800 SH SOLE 192800 0 0 KERYX BIOPHARMACEUTICALS INC COM 492515101 2018 200000 SH SOLE 200000 0 0 KYTHERA BIOPHARMACEUTICALS I COM 501570105 126 2765 SH SOLE 2765 0 0 LIFEPOINT HOSPITALS INC COM 53219L109 140 2995 SH SOLE 2995 0 0 MGC DIAGNOSTICS CORP COM 552768103 1910 174449 SH SOLE 174449 0 0 MAGELLAN HEALTH SVCS INC COM NEW 559079207 137 2290 SH SOLE 2290 0 0 MANNKIND CORP COM 56400P201 1650 289500 SH SOLE 289500 0 0 MAZOR ROBOTICS LTD SPONSORED ADS 57886P103 2993 177078 SH SOLE 177078 0 0 MEDGENICS INC COM NEW 58436Q203 1170 150000 SH SOLE 150000 0 0 MEDIVATION INC COM 58501N101 2892 48250 SH SOLE 48250 0 0 MEDNAX INC COM 58502B106 138 1375 SH SOLE 1375 0 0 MOLINA HEALTHCARE INC COM 60855R100 128 3590 SH SOLE 3590 0 0 MYLAN INC COM 628530107 17570 460305 SH SOLE 460305 0 0 MYRIAD GENETICS INC COM 62855J104 1370 58300 SH Call SOLE 58300 0 0 NPS PHARMACEUTICALS INC COM 62936P103 9726 305762 SH SOLE 305762 0 0 NANOSPHERE INC COM 63009F105 679 339500 SH SOLE 339500 0 0 NAVIDEA BIOPHARMACEUTICALS I COM 63937X103 309 116500 SH Put SOLE 116500 0 0 NEOSTEM INC COM PAR $.001 640650404 2835 331593 SH SOLE 331593 0 0 NEPTUNE TECHNOLOGIES BIORESO COM 64077P108 17120 5383857 SH SOLE 5383857 0 0 NEUROCRINE BIOSCIENCES INC COM 64125C109 3277 289500 SH Put SOLE 289500 0 0 NEUROCRINE BIOSCIENCES INC COM 64125C109 48344 4270704 SH SOLE 4270704 0 0 OMNICARE INC COM 681904108 140 2525 SH SOLE 2525 0 0 ONCOTHYREON INC COM 682324108 994 482500 SH SOLE 482500 0 0 ONYX PHARMACEUTICALS INC COM 683399109 69451 556944 SH SOLE 556944 0 0 PACIRA PHARMACEUTICALS INC COM 695127100 13078 272034 SH SOLE 272034 0 0 PROGENICS PHARMACEUTICALS IN COM 743187106 849 169068 SH SOLE 169068 0 0 PSIVIDA CORP COM 74440J101 3173 772000 SH SOLE 772000 0 0 QUESTCOR PHARMACEUTICALS INC COM 74835Y101 21828 376350 SH SOLE 376350 0 0 REPLIGEN CORP COM 759916109 757 68300 SH Put SOLE 68300 0 0 REPROS THERAPEUTICS INC COM NEW 76028H209 5172 193000 SH Call SOLE 193000 0 0 REPROS THERAPEUTICS INC COM NEW 76028H209 39710 1481733 SH SOLE 1481733 0 0 SANGAMO BIOSCIENCES INC COM 800677106 10123 965000 SH SOLE 965000 0 0 SANTARUS INC COM 802817304 12023 532243 SH SOLE 532243 0 0 SAREPTA THERAPEUTICS INC COM 803607100 95744 20272069 SH SOLE 20272069 0 0 SPECTRANETICS CORP COM 84760C107 2589 154079 SH SOLE 154079 0 0 STEMCELLS INC COM NEW 85857R204 389 231600 SH SOLE 231600 0 0 STEMLINE THERAPEUTICS INC COM 85858C107 4086 90208 SH SOLE 90208 0 0 SYNTA PHARMACEUTICALS CORP COM 87162T206 15026 2381236 SH SOLE 2381236 0 0 TEKMIRA PHARMACEUTICALS CORP COM NEW 87911B209 1112 159309 SH SOLE 159309 0 0 TESARO INC COM 881569107 58639 1513644 SH SOLE 1513644 0 0 TRANSGENOMIC INC COM 89365k206 838 2207500 SH SOLE 2207500 0 0 UROPLASTY INC COM NEW 917277204 1006 303989 SH SOLE 303989 0 0 VCA ANTECH INC COM 918194101 129 4715 SH SOLE 4715 0 0 VANDA PHARMACEUTICALS INC COM 921659108 1057 96500 SH Put SOLE 96500 0 0 VANDA PHARMACEUTICALS INC COM 921659108 5284 482600 SH Call SOLE 482600 0 0 VANDA PHARMACEUTICALS INC COM 921659108 9510 868500 SH SOLE 868500 0 0 VERASTEM INC COM 92337C104 3001 241065 SH SOLE 241065 0 0 VERTEX PHARMACEUTICALS INC COM 92532F100 34277 452095 SH SOLE 452095 0 0 VICAL INC COM 925602104 500 400000 SH Call SOLE 400000 0 0 VIVUS INC COM 928551100 2692 289500 SH Put SOLE 289500 0 0 WALGREEN CO COM 931422109 10107 187870 SH SOLE 187870 0 0 WELLCARE HEALTH PLANS INC COM 94946T106 9211 132081 SH SOLE 132081 0 0 XENOPORT INC COM 98411C100 274 48250 SH SOLE 48250 0 0 ZELTIQ AESTHETICS INC COM 98933Q108 124 13703 SH SOLE 13703 0 0