MET INVESTORS SERIES TRUST

5 Park Plaza, Suite 1900

Irvine, California 92614

VIA EDGAR

October 3, 2012

EDGAR Operations Branch

Division of Investment Management

Securities and Exchange Commission

100 F Street, N.E.

Washington, D.C. 20549

Re: Met Investors Series Trust (the “Trust”)

Files No. 333-48456

CIK – 0001126087

Ladies and Gentlemen:

Pursuant to Rule 497 under the Securities Act of 1933, enclosed is the interactive data file that mirrors the risk/return summary information in the supplement dated September 20, 2012 to the prospectus dated April 30, 2012 for the Rainier Large Cap Equity Portfolio, a series of the Trust, filed under Rule 497(e) on September 20, 2012.

Any questions or comments with respect to this filing may be directed to the undersigned at (617) 578-4036.

Very truly yours,

/s/ Michael P. Lawlor

Michael P. Lawlor

Enclosures

cc: John L. Chilton, Esq.