-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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 Wu3PKo4TBIIRC3ji/Qj/BA==

<SEC-DOCUMENT>0000919574-10-002182.txt : 20100309
<SEC-HEADER>0000919574-10-002182.hdr.sgml : 20100309
<ACCEPTANCE-DATETIME>20100309120003
ACCESSION NUMBER:		0000919574-10-002182
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20100305
FILED AS OF DATE:		20100309
DATE AS OF CHANGE:		20100309

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			RESPONSE GENETICS INC
		CENTRAL INDEX KEY:			0001124608
		STANDARD INDUSTRIAL CLASSIFICATION:	IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES [2835]
		IRS NUMBER:				000000000

	BUSINESS ADDRESS:	
		STREET 1:		1640 MARENGO ST.,
		STREET 2:		6TH FLOOR
		CITY:			LOS ANGELES,
		STATE:			CA
		ZIP:			90033
		BUSINESS PHONE:		(323) 224-3900

	MAIL ADDRESS:	
		STREET 1:		1640 MARENGO ST.,
		STREET 2:		6TH FLOOR
		CITY:			LOS ANGELES,
		STATE:			CA
		ZIP:			90033

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			LANSDOWNE PARTNERS LIMITED PARTNERSHIP
		CENTRAL INDEX KEY:			0001315309

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-33509
		FILM NUMBER:		10665989

	BUSINESS ADDRESS:	
		STREET 1:		15 DAVIES STREET
		CITY:			LONDON
		STATE:			X0
		ZIP:			W1K 3AG
		BUSINESS PHONE:		44-20-7290-5500

	MAIL ADDRESS:	
		STREET 1:		15 DAVIES STREET
		CITY:			LONDON
		STATE:			X0
		ZIP:			W1K 3AG

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			LANSDOWNE UK STRATEGIC INVESTMENT MASTER FUND LTD
		CENTRAL INDEX KEY:			0001469444

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-33509
		FILM NUMBER:		10665990

	BUSINESS ADDRESS:	
		STREET 1:		C/O FORTIS PRIME FUND SOLUTIONS
		STREET 2:		FORTIS HOUSE, PARK LANE, SPENCER DOCK
		CITY:			DUBLIN
		STATE:			L2
		ZIP:			1
		BUSINESS PHONE:		353 1 607 1800

	MAIL ADDRESS:	
		STREET 1:		C/O FORTIS PRIME FUND SOLUTIONS
		STREET 2:		FORTIS HOUSE, PARK LANE, SPENCER DOCK
		CITY:			DUBLIN
		STATE:			L2
		ZIP:			1
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>p1079251.xml
<DESCRIPTION>LANSDOWNE/RESPONSE GENETICS
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2010-03-05</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001124608</issuerCik>
        <issuerName>RESPONSE GENETICS INC</issuerName>
        <issuerTradingSymbol>RGDX</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001315309</rptOwnerCik>
            <rptOwnerName>LANSDOWNE PARTNERS LIMITED PARTNERSHIP</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>15 DAVIES STREET</rptOwnerStreet1>
            <rptOwnerStreet2>LONDON</rptOwnerStreet2>
            <rptOwnerCity>W1K 3AG</rptOwnerCity>
            <rptOwnerState>X0</rptOwnerState>
            <rptOwnerZipCode></rptOwnerZipCode>
            <rptOwnerStateDescription>UNITED KINGDOM</rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle></officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001469444</rptOwnerCik>
            <rptOwnerName>LANSDOWNE UK STRATEGIC INVESTMENT MASTER FUND LTD</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O FORTIS PRIME FUND SOLUTIONS</rptOwnerStreet1>
            <rptOwnerStreet2>FORTIS HOUSE, PARK LANE, SPENCER DOCK</rptOwnerStreet2>
            <rptOwnerCity>DUBLIN I</rptOwnerCity>
            <rptOwnerState>L2</rptOwnerState>
            <rptOwnerZipCode></rptOwnerZipCode>
            <rptOwnerStateDescription>IRELAND</rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle></officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock, par value $0.01 per share</value>
            </securityTitle>
            <transactionDate>
                <value>2010-03-05</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>P</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionTimeliness></transactionTimeliness>
            <transactionAmounts>
                <transactionShares>
                    <value>600769</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>1.31</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>3658676</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                    <footnoteId id="F1"/>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock, par value $0.01 per share</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>3658676</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See Footnote</value>
                    <footnoteId id="F2"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">These reported securities are held in the account of Lansdowne UK Strategic Investment Master Fund Limited (the &quot;Master Fund&quot;).  The Master Fund entered into a
purchase agreement with the Issuer as of March 5, 2010 whereby the Master Fund acquired 600,769 shares of common stock from the Issuer in a private transaction
(the &quot;Acquisition&quot;).  The Master Fund entered into the Acquisition in order to maintain the same percentage of common stock that it beneficially owned prior to the
issuance of additional shares of equity securities by the Issuer.  Therefore, the percentage of shares beneficially owned by the Master Fund did not change as a
result of the Acquisition.</footnote>
        <footnote id="F2">These reported securities are held in the account of the Master Fund and may be deemed to be beneficially owned by Lansdowne Partners Limited Partnership by
virtue of its role as the investment advisor of the Fund.  Lansdowne Partners Limited Partnership disclaims beneficial ownership of the reported securities except to
the extent of its pecuniary interest therein, and this report shall not be deemed an admission that Lansdowne Partners Limited Partnership is the beneficial owner of
these securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>Lansdowne Partners Limited Partnership, By: Lansdowne Partners Limited, its general partner, By: /s/ Paul Ruddock, Director</signatureName>
        <signatureDate>2010-03-09</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>Lansdowne UK Strategic Investment Master Fund Limited, By: Lansdowne Partners Limited Partnership, its investment advisor, By: Lansdowne Partners Limited, its general partner, By: /s/ Paul Ruddock, Director</signatureName>
        <signatureDate>2010-03-09</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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