-----BEGIN PRIVACY-ENHANCED MESSAGE----- Proc-Type: 2001,MIC-CLEAR Originator-Name: webmaster@www.sec.gov Originator-Key-Asymmetric: MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB MIC-Info: RSA-MD5,RSA, EowyuFmyRgqkMDbSR7q4JRfEvQa148YEoDjGrIB+h3B3TDMjsx2X6PNNE/lmI6e1 g+ZMY7veYIkkc495u8L2Iw== 0001012975-05-000027.txt : 20050209 0001012975-05-000027.hdr.sgml : 20050209 20050209165430 ACCESSION NUMBER: 0001012975-05-000027 CONFORMED SUBMISSION TYPE: SC 13G/A PUBLIC DOCUMENT COUNT: 1 FILED AS OF DATE: 20050209 DATE AS OF CHANGE: 20050209 GROUP MEMBERS: ASCENT MANAGEMENT SBIC CORP. GROUP MEMBERS: ASCENT VENTURE MANAGEMENT II, L.P. GROUP MEMBERS: ASCENT VENTURE MANAGEMENT, LLC GROUP MEMBERS: ASCENT VENTURE PARTNERS II, L.P. GROUP MEMBERS: CHRISTOPHER W. DICK GROUP MEMBERS: CHRISTOPHER W. LYNCH GROUP MEMBERS: FRANK M. POLESTRA SUBJECT COMPANY: COMPANY DATA: COMPANY CONFORMED NAME: HARVARD BIOSCIENCE INC CENTRAL INDEX KEY: 0001123494 STANDARD INDUSTRIAL CLASSIFICATION: LABORATORY ANALYTICAL INSTRUMENTS [3826] IRS NUMBER: 043306140 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: SC 13G/A SEC ACT: 1934 Act SEC FILE NUMBER: 005-60603 FILM NUMBER: 05589394 BUSINESS ADDRESS: STREET 1: 84 OCTOBER HILL RD CITY: HOLLISTON STATE: MA ZIP: 01746 BUSINESS PHONE: 5088938999 MAIL ADDRESS: STREET 1: 84 OCTOBER HILL ROAD CITY: HOLLISTON STATE: MA ZIP: 01746 FILED BY: COMPANY DATA: COMPANY CONFORMED NAME: ASCENT VENTURE PARTNERS LP CENTRAL INDEX KEY: 0001134377 IRS NUMBER: 043458591 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: SC 13G/A BUSINESS ADDRESS: STREET 1: C/O ASCENT VENTURE MANAGEMENT INC STREET 2: 255 STATE STREET 5TH FLOOR CITY: BOSTON STATE: MA ZIP: 02109 BUSINESS PHONE: 6177209400 MAIL ADDRESS: STREET 1: C/O ASCENT VENTURE MANAGEMENT INC STREET 2: 255 STATE STREET 5TH FLOOR CITY: BOSTON STATE: MA ZIP: 02109 SC 13G/A 1 exitfilingsc13g.txt SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(b)(c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2(b) (Amendment No. 3 )* --------- HARVARD BIOSCIENCE, INC. - -------------------------------------------------------------------------------- (Name of Issuer) COMMON STOCK, $.01 PAR VALUE PER SHARE - -------------------------------------------------------------------------------- (Title of Class of Securities) 416906 10 5 --------------------------------------- (CUSIP Number) DECEMBER 31, 2004 - -------------------------------------------------------------------------------- (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is filed: [_] Rule 13d-1(b) [_] Rule 13d-1(c) [X] Rule 13d-1(d) * The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page. The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes). Page 1 of 17 CUSIP No. 416906 10 5 13G Page 2 of 17 Pages --------------- --- ---- ________________________________________________________________________________ 1. NAME OF REPORTING PERSONS I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY) Ascent Venture Partners, L.P. 04-3458591 ________________________________________________________________________________ 2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [_] (b) [_] ________________________________________________________________________________ 3. SEC USE ONLY ________________________________________________________________________________ 4. CITIZENSHIP OR PLACE OF ORGANIZATION Delaware ________________________________________________________________________________ NUMBER OF 5. SOLE VOTING POWER SHARES 0 shares _________________________________________________________________ BENEFICIALLY 6. SHARED VOTING POWER OWNED BY 0 shares _________________________________________________________________ EACH 7. SOLE DISPOSITIVE POWER REPORTING 0 shares _________________________________________________________________ PERSON 8. SHARED DISPOSITIVE POWER WITH 0 shares ________________________________________________________________________________ 9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 0 shares ________________________________________________________________________________ 10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES* [_] ________________________________________________________________________________ 11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9 0.00% ________________________________________________________________________________ 12. TYPE OF REPORTING PERSON* PN ________________________________________________________________________________ *SEE INSTRUCTIONS BEFORE FILLING OUT! Page 2 of 17 CUSIP No. 416906 10 5 13G Page 3 of 17 Pages --------------- --- ---- ________________________________________________________________________________ 1. NAME OF REPORTING PERSONS I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY) Ascent Venture Management, LLC 04-3458587 ________________________________________________________________________________ 2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [_] (b) [_] ________________________________________________________________________________ 3. SEC USE ONLY ________________________________________________________________________________ 4. CITIZENSHIP OR PLACE OF ORGANIZATION Delaware ________________________________________________________________________________ NUMBER OF 5. SOLE VOTING POWER SHARES 0 shares _________________________________________________________________ BENEFICIALLY 6. SHARED VOTING POWER OWNED BY 2,500 shares _________________________________________________________________ EACH 7. SOLE DISPOSITIVE POWER REPORTING 0 shares _________________________________________________________________ PERSON 8. SHARED DISPOSITIVE POWER WITH 2,500 shares ________________________________________________________________________________ 9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 2,500 shares ________________________________________________________________________________ 10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES* [_] ________________________________________________________________________________ 11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9 0.01% ________________________________________________________________________________ 12. TYPE OF REPORTING PERSON* PN ________________________________________________________________________________ *SEE INSTRUCTIONS BEFORE FILLING OUT! Page 3 of 17 CUSIP No. 416906 10 5 13G Page 4 of 17 Pages --------------- --- ---- ________________________________________________________________________________ 1. NAME OF REPORTING PERSONS I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY) Ascent Venture Partners II, L.P. 04-3263775 ________________________________________________________________________________ 2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [_] (b) [_] ________________________________________________________________________________ 3. SEC USE ONLY ________________________________________________________________________________ 4. CITIZENSHIP OR PLACE OF ORGANIZATION Delaware ________________________________________________________________________________ NUMBER OF 5. SOLE VOTING POWER SHARES 0 shares _________________________________________________________________ BENEFICIALLY 6. SHARED VOTING POWER OWNED BY 0 shares _________________________________________________________________ EACH 7. SOLE DISPOSITIVE POWER REPORTING 0 shares _________________________________________________________________ PERSON 8. SHARED DISPOSITIVE POWER WITH 0 shares ________________________________________________________________________________ 9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 0 shares ________________________________________________________________________________ 10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES* [_] ________________________________________________________________________________ 11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9 0.00% ________________________________________________________________________________ 12. TYPE OF REPORTING PERSON* PN ________________________________________________________________________________ *SEE INSTRUCTIONS BEFORE FILLING OUT! Page 4 of 17 CUSIP No. 416906 10 5 13G Page 5 of 17 Pages --------------- --- ---- ________________________________________________________________________________ 1. NAME OF REPORTING PERSONS I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY) Ascent Venture Management II, L.P. 04-3262868 ________________________________________________________________________________ 2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [_] (b) [_] ________________________________________________________________________________ 3. SEC USE ONLY ________________________________________________________________________________ 4. CITIZENSHIP OR PLACE OF ORGANIZATION Delaware ________________________________________________________________________________ NUMBER OF 5. SOLE VOTING POWER SHARES 0 shares _________________________________________________________________ BENEFICIALLY 6. SHARED VOTING POWER OWNED BY 0 shares _________________________________________________________________ EACH 7. SOLE DISPOSITIVE POWER REPORTING 0 shares _________________________________________________________________ PERSON 8. SHARED DISPOSITIVE POWER WITH 0 shares ________________________________________________________________________________ 9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 0 shares ________________________________________________________________________________ 10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES* [_] ________________________________________________________________________________ 11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9 0.00% ________________________________________________________________________________ 12. TYPE OF REPORTING PERSON* PN ________________________________________________________________________________ *SEE INSTRUCTIONS BEFORE FILLING OUT! Page 5 of 17 CUSIP No. 416906 10 5 13G Page 6 of 17 Pages --------------- --- ---- ________________________________________________________________________________ 1. NAME OF REPORTING PERSONS I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY) Ascent Management SBIC Corp. 04-3262812 ________________________________________________________________________________ 2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [_] (b) [_] ________________________________________________________________________________ 3. SEC USE ONLY ________________________________________________________________________________ 4. CITIZENSHIP OR PLACE OF ORGANIZATION Massachusetts ________________________________________________________________________________ NUMBER OF 5. SOLE VOTING POWER SHARES 0 shares _________________________________________________________________ BENEFICIALLY 6. SHARED VOTING POWER OWNED BY 0 shares _________________________________________________________________ EACH 7. SOLE DISPOSITIVE POWER REPORTING 0 shares _________________________________________________________________ PERSON 8. SHARED DISPOSITIVE POWER WITH 0 shares ________________________________________________________________________________ 9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 0 shares ________________________________________________________________________________ 10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES* [_] ________________________________________________________________________________ 11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9 0.00% ________________________________________________________________________________ 12. TYPE OF REPORTING PERSON* CO ________________________________________________________________________________ *SEE INSTRUCTIONS BEFORE FILLING OUT! Page 6 of 17 CUSIP No. 416906 10 5 13G Page 7 of 17 Pages --------------- --- ---- ________________________________________________________________________________ 1. NAME OF REPORTING PERSONS I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY) Christopher W. Dick ________________________________________________________________________________ 2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [_] (b) [_] ________________________________________________________________________________ 3. SEC USE ONLY ________________________________________________________________________________ 4. CITIZENSHIP OR PLACE OF ORGANIZATION United States ________________________________________________________________________________ NUMBER OF 5. SOLE VOTING POWER SHARES 3,500 shares _________________________________________________________________ BENEFICIALLY 6. SHARED VOTING POWER OWNED BY 2,500 shares _________________________________________________________________ EACH 7. SOLE DISPOSITIVE POWER REPORTING 3,500 shares _________________________________________________________________ PERSON 8. SHARED DISPOSITIVE POWER WITH 2,500 shares ________________________________________________________________________________ 9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 6,000 shares ________________________________________________________________________________ 10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES* [_] ________________________________________________________________________________ 11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9 0.02% ________________________________________________________________________________ 12. TYPE OF REPORTING PERSON* IN ________________________________________________________________________________ *SEE INSTRUCTIONS BEFORE FILLING OUT! Page 7 of 17 CUSIP No. 416906 10 5 13G Page 8 of 17 Pages --------------- --- ---- ________________________________________________________________________________ 1. NAME OF REPORTING PERSONS I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY) Christopher W. Lynch ________________________________________________________________________________ 2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [_] (b) [_] ________________________________________________________________________________ 3. SEC USE ONLY ________________________________________________________________________________ 4. CITIZENSHIP OR PLACE OF ORGANIZATION United States ________________________________________________________________________________ NUMBER OF 5. SOLE VOTING POWER SHARES 0 shares _________________________________________________________________ BENEFICIALLY 6. SHARED VOTING POWER OWNED BY 2,500 shares _________________________________________________________________ EACH 7. SOLE DISPOSITIVE POWER REPORTING 0 shares _________________________________________________________________ PERSON 8. SHARED DISPOSITIVE POWER WITH 2,500 shares ________________________________________________________________________________ 9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 2,500 shares ________________________________________________________________________________ 10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES* [_] ________________________________________________________________________________ 11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9 0.01% ________________________________________________________________________________ 12. TYPE OF REPORTING PERSON* IN ________________________________________________________________________________ *SEE INSTRUCTIONS BEFORE FILLING OUT! Page 8 of 17 CUSIP No. 416906 10 5 13G Page 8 of 17 Pages --------------- --- ---- ________________________________________________________________________________ 1. NAME OF REPORTING PERSONS I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY) Frank M. Polestra ________________________________________________________________________________ 2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [_] (b) [_] ________________________________________________________________________________ 3. SEC USE ONLY ________________________________________________________________________________ 4. CITIZENSHIP OR PLACE OF ORGANIZATION United States ________________________________________________________________________________ NUMBER OF 5. SOLE VOTING POWER SHARES 5,000 shares _________________________________________________________________ BENEFICIALLY 6. SHARED VOTING POWER OWNED BY 2,500 shares _________________________________________________________________ EACH 7. SOLE DISPOSITIVE POWER REPORTING 5,000 shares _________________________________________________________________ PERSON 8. SHARED DISPOSITIVE POWER WITH 2,500 shares ________________________________________________________________________________ 9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 7,500 shares ________________________________________________________________________________ 10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES* [_] ________________________________________________________________________________ 11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9 0.02% ________________________________________________________________________________ 12. TYPE OF REPORTING PERSON* IN ________________________________________________________________________________ *SEE INSTRUCTIONS BEFORE FILLING OUT! Page 9 of 17 CUSIP No. 416906 10 5 13G Page 10 of 17 Pages --------------- --- ---- SCHEDULE 13G Item 1(a). NAME OF ISSUER: Harvard Bioscience, Inc. Item 1(b). ADDRESS OF ISSUER'S PRINCIPAL EXECUTIVE OFFICES: 84 October Hill Road, Holliston, Massachusetts 01746. Item 2(a). NAMES OF PERSONS FILING: (1) Ascent Venture Partners, L.P.; (2) Ascent Venture Management, LLC (the sole general partner of Ascent Venture Partners, L.P.); (3) Ascent Venture Partners II, L.P.; (4) Ascent Venture Management II, L.P. (the sole general partner of Ascent Venture Partners II, L.P.); (5) Ascent Management SBIC Corp. (the sole general partner of Ascent Venture Management II, L.P.); and (6) Christopher W. Dick, Christopher W. Lynch and Frank M. Polestra (the managing members of Ascent Venture Management, LLC, and the stockholders of Ascent Management SBIC Corporation). Item 2(b). ADDRESS OF PRINCIPAL BUSINESS OFFICE OR, IF NONE, RESIDENCE: The address of the principal business office of each of Ascent Venture Partners, L.P.; Ascent Venture Management, LLC; Ascent Venture Partners II, L.P.; Ascent Venture Management II, L.P.; Ascent Management SBIC Corp.; Christopher W. Dick; Christopher W. Lynch and Frank M. Polestra is 255 State Street, 5th Floor, Boston, MA 02109. Item 2(c). CITIZENSHIP: Each of Ascent Venture Partners, L.P., Ascent Venture Partners II, L.P., and Ascent Venture Management II, L.P. is a limited partnership organized under the laws of the State of Delaware. Ascent Venture Management, LLC is a Delaware limited liability company. Ascent Management SBIC Corp. is a Massachusetts S-corporation. Each of Christopher W. Dick, Christopher W. Lynch and Frank M. Polestra is a United States citizen. Item 2(d). TITLE OF CLASS OF SECURITIES: Common Stock, $.01 par value per share (the "Common Stock"). Item 2(e). CUSIP NUMBER: 416906 10 5 Page 10 of 17 CUSIP No. 416906 10 5 13G Page 11 of 17 Pages --------------- --- ---- Item 4. OWNERSHIP. (a) Amount Beneficially Owned: As of December 31, 2004, Ascent Venture Partners, L.P. was the record holder of 0 shares of Common Stock; Ascent Venture Partners II, L.P. was the record holder of 0 shares of Common Stock; Ascent Venture Management, LLC was the record holder of 2,500 shares of Common Stock (the "AVM Shares"); Christopher W. Dick was the record holder of 3,500 shares of Common Stock (the "C.W. Dick Shares"); and Frank M. Polestra was the record holder of 5,000 shares of Common Stock (the "Polestra Shares"). As a managing member of Ascent Venture Management, LLC, Christopher W. Dick may be deemed to beneficially own the AVM Shares and the C.W. Dick Shares, for an aggregate of 6,000 shares. As a managing member of Ascent Venture Management, LLC, Christopher W. Lynch may be deemed to beneficially own the AVM Shares. As a managing member of Ascent Venture Management, LLC, Frank M. Polestra may be deemed to beneficially own the AVM Shares and the Polestra Shares, for an aggregate of 7,500 shares. Each of the reporting persons expressly disclaims beneficial ownership, except to the extent of his or its pecuniary interest therein, if any, and except in the case of the shares that such reporting person owns beneficially as set forth above, of any shares of Common Stock of Harvard Bioscience, Inc. (b) Percent of Class: Ascent Venture Partners, L.P. 0.00% Ascent Venture Management, LLC 0.01% Ascent Venture Partners II, L.P. 0.00% Ascent Venture Management II, L.P. 0.00% Ascent Management SBIC Corp. 0.00% Christopher W. Dick 0.02% Christopher W. Lynch 0.01% Frank M. Polestra 0.02% The foregoing percentages are calculated based on the 30,347,426 shares of Common Stock of Harvard Bioscience outstanding as of November 1, 2004 as reported in the Issuer's Form 10-Q filed with the SEC on November 9, 2004. (c) Number of shares as to which such person has: (i) sole power to vote or to direct the vote: Page 11 of 17 CUSIP No. 416906 10 5 13G Page 12 of 17 Pages --------------- --- ---- Christopher W. Dick 3,500 Frank M. Polestra 5,000 0 shares for each other reporting person (ii) shared power to vote or to direct the vote: Ascent Venture Management, LLC 2,500 Christopher W. Dick 2,500 Frank M. Polestra 2,500 0 shares for each other reporting person (iii)sole power to dispose or direct the disposition of: Christopher W. Dick 3,500 Frank M. Polestra 5,000 0 shares for each other reporting person (iv) shared power to dispose or direct the disposition of: Ascent Venture Management, LLC 2,500 Christopher W. Dick 2,500 Frank M. Polestra 2,500 0 shares for each other reporting person Item 5. OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS. If this statement is being filed to report the fact that as of the date hereof each of the reporting persons has ceased to be the beneficial owner of more than five percent of the class of securities, check the following [X] ALL OTHER ITEMS REPORTED ON THE SCHEDULE 13G (AMENDMENT NO. 2) DATED AS OF FEBRUARY 11, 2003 AND FILED ON BEHALF OF THE REPORTING PERSONS WITH RESPECT TO THE COMMON STOCK OF HARVARD BIOSCIENCE, INC. REMAIN UNCHANGED. Page 12 of 17 CUSIP No. 416906 10 5 13G Page 13 of 17 Pages --------------- --- ---- SIGNATURE After reasonable inquiry and to the best of its knowledge and belief, each of the undersigned certifies that the information set forth in this statement is true, complete and correct. We also hereby agree to file this statement jointly pursuant to the Agreement listed on EXHIBIT 1 hereto. Date: February 9, 2005 ASCENT VENTURE PARTNERS, L.P. By: Ascent Venture Management, LLC By: /s/ Christopher W. Dick ------------------------------------ Christopher W. Dick, Managing Member ASCENT VENTURE MANAGEMENT, LLC By: /s/ Christopher W. Dick ------------------------------------ Christopher W. Dick, Managing Member ASCENT VENTURE PARTNERS II, L.P. By: Ascent Venture Management II, L.P. By: Ascent Management SBIC Corp. By: /s/ Christopher W. Dick ------------------------------------ Christopher W. Dick, Vice President ASCENT VENTURE MANAGEMENT II, L.P. By: Ascent Management SBIC Corp. By: /s/ Christopher W. Dick ------------------------------------ Christopher W. Dick, Vice President ASCENT MANAGEMENT SBIC CORP. By: /s/ Christopher W. Dick ------------------------------------ Christopher W. Dick, Vice President Page 13 of 17 CUSIP No. 416906 10 5 13G Page 14 of 17 Pages --------------- --- ---- /s/ Christopher W. Dick - --------------------------------------- Christopher W. Dick /s/ Christopher W. Lynch - ------------------------------------------------- Christopher W. Lynch /s/ Frank M. Polestra - --------------------------------------- Frank M. Polestra Page 14 of 17 CUSIP No. 416906 10 5 13G Page 15 of 17 Pages --------------- --- ---- Exhibit Index EXHIBIT NO. DESCRIPTION PAGE NO. ----------- ----------- -------- 1 Agreement of Joint Filing 16 Page 15 of 17 CUSIP No. 416906 10 5 13G Page 16 of 17 Pages --------------- --- ---- EXHIBIT 1 AGREEMENT OF JOINT FILING Pursuant to Rule 13d-1(k)(1) under the Securities Exchange Act of 1934, the undersigned hereby agree that only one statement containing the information required by Schedule 13G need be filed with respect to the ownership by each of the undersigned of shares of Common Stock of Harvard Bioscience, Inc. EXECUTED this 9th day of February, 2005. ASCENT VENTURE PARTNERS, L.P. By: Ascent Venture Management, LLC By: /s/ Christopher W. Dick ------------------------------------ Christopher W. Dick, Managing Member ASCENT VENTURE MANAGEMENT, LLC By: /s/ Christopher W. Dick ------------------------------------ Christopher W. Dick, Managing Member ASCENT VENTURE PARTNERS II, L.P. By: Ascent Venture Management II, L.P. By: Ascent Management SBIC Corp. By: /s/ Christopher W. Dick ------------------------------------ Christopher W. Dick, Vice President ASCENT VENTURE MANAGEMENT II, L.P. By: Ascent Management SBIC Corp. By: /s/ Christopher W. Dick ------------------------------------ Christopher W. Dick, Vice President ASCENT MANAGEMENT SBIC CORP. By: /s/ Christopher W. Dick ------------------------------------ Christopher W. Dick, Vice President Page 16 of 17 CUSIP No. 416906 10 5 13G Page 17 of 17 Pages --------------- --- ---- /s/ Christopher W. Dick - --------------------------------------- Christopher W. Dick /s/ Christopher W. Lynch - -------------------------------------------- Christopher W. Lynch /s/ Frank M. Polestra - --------------------------------------- Frank M. Polestra Page 17 of 17 -----END PRIVACY-ENHANCED MESSAGE-----