-----BEGIN PRIVACY-ENHANCED MESSAGE----- Proc-Type: 2001,MIC-CLEAR Originator-Name: webmaster@www.sec.gov Originator-Key-Asymmetric: MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB MIC-Info: RSA-MD5,RSA, ThM6xN1shm1uzxndAu9K0Pce6oPXY3fzACpqHEZ/u2avfLU0F4WCpxrPn6MDQPxN lp6lx30Fu9GDRYAhbbd4nw== 0000930413-08-001585.txt : 20080310 0000930413-08-001585.hdr.sgml : 20080310 20080310122906 ACCESSION NUMBER: 0000930413-08-001585 CONFORMED SUBMISSION TYPE: SC 13G/A PUBLIC DOCUMENT COUNT: 1 FILED AS OF DATE: 20080310 DATE AS OF CHANGE: 20080310 SUBJECT COMPANY: COMPANY DATA: COMPANY CONFORMED NAME: KERYX BIOPHARMACEUTICALS INC CENTRAL INDEX KEY: 0001114220 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 134087132 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: SC 13G/A SEC ACT: 1934 Act SEC FILE NUMBER: 005-78786 FILM NUMBER: 08676816 BUSINESS ADDRESS: STREET 1: 750 LEXINGTON AVENUE STREET 2: . CITY: NEW YORK STATE: NY ZIP: 10022 BUSINESS PHONE: 212-531-5965 FILED BY: COMPANY DATA: COMPANY CONFORMED NAME: TIAA CREF INVESTMENT MANAGEMENT LLC CENTRAL INDEX KEY: 0000887793 IRS NUMBER: 133586142 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: SC 13G/A BUSINESS ADDRESS: STREET 1: 730 THIRD AVENUE CITY: NEW YORK STATE: NY ZIP: 10017-3206 BUSINESS PHONE: 2129166042 MAIL ADDRESS: STREET 1: 730 THIRD AVENUE CITY: NEW YORK STATE: NY ZIP: 10017-3206 FORMER COMPANY: FORMER CONFORMED NAME: TIAA CREF INVESTMENT MANAGEMENT INC DATE OF NAME CHANGE: 19980223 SC 13G/A 1 c52664_sc13g-a.htm

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

(Rule 13d-102)

Information to be Included in Statements Filed Pursuant to §240.13d-1(b), (c)
and (d) and Amendments Thereto Filed Pursuant to §240.13d-2

Under the Securities Exchange Act of 1934
(Amendment No. 2 )*

Keryx Biopharmaceuticals
______________________________
(Name of Issuer)

Common Stock
______________________________
(Title of Class of Securities)

492515101
______________________________
(CUSIP Number)

     February 29, 2008
_______________________________________________________
(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

(x) Rule 13d-1(b)
( ) Rule 13d-1(c)
( ) Rule 13d-1(d)

 
*The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

(Continued on following page(s))




1.
  NAME OF REPORTING PERSONS        
             
  TIAA-CREF Investment Management, LLC        
         
2.
  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP   (a) ( )
              (b) ( )
3.
  SEC USE ONLY        
4.
  CITIZENSHIP OR PLACE OF ORGANIZATION        
             
  Delaware        
         
NUMBER OF SHARES BENEFICIALLY OWNED
       
BY EACH REPORTING PERSON WITH:
       
                 
 
5.
  SOLE VOTING POWER   4,005,598    
                 
 
6.
  SHARED VOTING POWER   0    
                 
 
7.
  SOLE DISPOSITIVE POWER   4,005,598    
                 
 
8.
  SHARED DISPOSITIVE POWER   0    
     
9.
  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
             
  4,005,598        
     
10.
  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN
  SHARES                                                                                 ( )        
11.
  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9    
             
  9.15%        
             
12.
  TYPE OF REPORTING PERSON        
             
    IA        
 



1.
  NAME OF REPORTING PERSONS        
             
 
College Retirement Equities Fund - Stock Account
       
         
2.
  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP   (a) ( )
              (b) ( )
3.
  SEC USE ONLY        
4.
 
CITIZENSHIP OR PLACE OF ORGANIZATION
       
             
  New York        
         
NUMBER OF SHARES BENEFICIALLY OWNED
       
BY EACH REPORTING PERSON WITH:
       
                 
 
5.
  SOLE VOTING POWER   0    
                 
 
6.
  SHARED VOTING POWER   3,026,444    
                 
 
7.
  SOLE DISPOSITIVE POWER   0    
                 
 
8.
  SHARED DISPOSITIVE POWER   3,026,444    
     
9.
  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
             
  3,026,444        
     
10.
  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
  CERTAIN SHARES                                                               ( )        
11.
  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9    
             
  6.92%        
12.
  TYPE OF REPORTING PERSON        
             
  IV        
             



1.
  NAME OF REPORTING PERSONS        
             
  Teachers Advisors, Inc.        
             
2.
  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP   (a) ( )
              (b) ( )
3.
  SEC USE ONLY        
4.
  CITIZENSHIP OR PLACE OF ORGANIZATION        
             
  Delaware        
NUMBER OF SHARES BENEFICIALLY OWNED
       
BY EACH REPORTING PERSON WITH:
       
         
 
5.
  SOLE VOTING POWER   715,212    
                 
 
6.
  SHARED VOTING POWER   0    
                 
 
7.
  SOLE DISPOSITIVE POWER   715,212    
                 
 
8.
  SHARED DISPOSITIVE POWER   0    
                 
9.
  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
     
  715,212        
             
10.
  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN
  SHARES                                                                                    ( )        
11.
  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9    
         
  1.64%        
             
12.
  TYPE OF REPORTING PERSON        
             
  IA        
             


Item 1(a). NAME OF ISSUER:
     
                     Keryx Biopharmaceuticals
   
Item 1(b). ADDRESS OF ISSUER'S PRINCIPAL EXECUTIVE OFFICES:
     
                     750 Lexington Avenue
                     New York, NY 10022
   
Items 2(a)-2(c).                  NAME, ADDRESS OF PRINCIPAL BUSINESS OFFICE, AND CITIZENSHIP
                     OF PERSONS FILING:
     
                     TIAA-CREF Investment Management, LLC (“Investment Management”)
                     730 Third Avenue
                     New York, NY 10017-3206
                     Citizenship: Delaware
     
                     College Retirement Equities Fund-Stock Account (“CREF Stock Account”)
                     730 Third Avenue
                     New York, NY 10017-3206
                     Citizenship: New York
     
                     Teachers Advisors, Inc. (“Advisors”)
                     730 Third Avenue
                     New York, NY 10017-3206
                     Citizenship: Delaware
   
Item 2(d). TITLE OF CLASS OF SECURITIES:
     
                     Common Stock
   
Item 2(e). CUSIP NUMBER: 492515101
     
Item 3.   IF THIS STATEMENT IS FILED PURSUANT TO RULES 13d-1(b), OR 13d-2(b) or
    (c), CHECK WHETHER THE PERSON FILING IS A:
 
Investment Management
     
(a)
( )
Broker or dealer registered under Section 15 of the Exchange Act.
     
(b)
( )
Bank as defined in Section 3(a)(6) of the Exchange Act.
     
(c)
( )
Insurance Company as defined in Section 3(a)(19) of the Exchange Act.
     
(d)
( )
Investment Company registered under Section 8 of the Investment Company Act.
     
(e)
(x)
An investment adviser in accordance with Rule 13d-1(b)(1)(ii)(E).
     
(f)
( )
An employee benefit plan or endowment fund in accordance with Rule 13d-1(b)(1)(ii)(F).
     
(g)
( )
A parent holding company or control person in accordance with Rule 13d-1(b)(1)(ii)(G).
     
(h)
( )
A savings association as defined in Section 3(b) of the Federal Deposit Insurance
 
Act.
     
(i)
( )
A church plan that is excluded from the definition of an
 
investment company under Section 3(c)(14) of the Investment Company Act.
     
(j)
( )
Group, in accordance with Rule 13d-1(b)(1)(ii)(J).
     



CREF Stock Account
     
(a)
( )
Broker or dealer registered under Section 15 of the Exchange Act.
     
(b)
( )
Bank as defined in Section 3(a)(6) of the Exchange Act.
     
(c)
( )
Insurance Company as defined in Section 3(a)(19) of the Exchange Act.
     
(d)
(x)
Investment Company registered under Section 8 of the Investment Company Act.
     
(e)
( )
An investment adviser in accordance with Rule 13d-1(b)(1)(ii)(E).
     
(f)
( )
An employee benefit plan or endowment fund in accordance with Rule 13d-1(b)(1)(ii)(F).
     
(g)
( )
A parent holding company or control person in accordance with Rule 13d-1(b)(1)(ii)(G).
     
(h)
( )
A savings association as defined in Section 3(b) of the Federal Deposit Insurance
 
Act.
(i)
( )
A church plan that is excluded from the definition of an
 
investment company under Section 3(c)(14) of the Investment Company Act.
(j)
( )
Group, in accordance with Rule 13d-1(b)(1)(ii)(J).
 
Advisors  
     
(a)
( )
Broker or dealer registered under Section 15 of the Exchange Act.
     
(b)
( )
Bank as defined in Section 3(a)(6) of the Exchange Act.
     
(c)
( )
Insurance Company as defined in Section 3(a)(19) of the Exchange Act.
     
(d)
( )
Investment Company registered under Section 8 of the Investment Company Act.
     
(e)
(x)
An investment adviser in accordance with Rule 13d-1(b)(1)(ii)(E).
     
(f)
( )
An employee benefit plan or endowment fund in accordance with Rule 13d-1(b)(1)(ii)(F).
     
(g)
( )
A parent holding company or control person in accordance with Rule 13d-1(b)(1)(ii)(G).
     
(h)
( )
A savings association as defined in Section 3(b) of the Federal Deposit Insurance
 
Act.
(i)
( )
A church plan that is excluded from the definition of an
 
investment company under Section 3(c)(14) of the Investment Company Act.
     
(j)
( )
Group, in accordance with Rule 13d-1(b)(1)(ii)(J).
 
If this statement is filed pursuant to Rule 13d-1(c), check this box. ( )
 



Item 4. OWNERSHIP      
         
  (a) Aggregate amount beneficially owned: 4,720,810 (See Exhibit A attached)    
         
  (b) Percent of class: 10.79%    
       
  (c) Powers of shares:    
         
    Investment Management
CREF- Stock Account
Advisors
Sole Voting Power: 4,005,598
0
715,212
       
Shared Voting Power: 0
3,026,444
0
       
Sole Dispositive Power: 4,005,598
0
715,212
       
Shared Dispositive Power: 0
3,026,444
0

Item 5. OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS.
   
  If this statement is being filed to report the fact that as of the date hereof the reporting
  person has ceased to be the beneficial owner of more than five percent of the class of
  securities, check the following ( ).
   
Item 6. OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER
  PERSON.
   
  See Exhibit A attached
   
Item 7. IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH
  ACQUIRED THE SECURITY BEING REPORTED ON BY THE PARENT HOLDING
  COMPANY.
   
  Not Applicable
   
Item 8. IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP.
   
  Not Applicable
   
Item 9. NOTICE OF DISSOLUTION OF GROUP.
   
  Not Applicable
 
Item 10. CERTIFICATION.
   
  By signing below I certify that, to the best of my knowledge and belief, the securities
  referred to above were acquired and are held in the ordinary course of business and were
  not acquired and are not held for the purpose of or with the effect of changing or
  influencing the control of the issuer of the securities and were not acquired and are not
  held in connection with or as a participant in any transaction having that purpose or
  effect.
   



SIGNATURE.

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Date: March 10, 2008

TIAA-CREF INVESTMENT
MANAGEMENT, LLC
 
By: /s/ Michael Albert_
Michael Albert
Managing Director
 
COLLEGE RETIREMENT EQUITIES
FUND-STOCK ACCOUNT
 
By: /s/ Michael Albert_
Michael Albert
Managing Director Control Services
 
TEACHERS ADVISORS, INC.
 
By: /s/ Michael Albert
Michael Albert
Managing Director



EXHIBIT A

ITEM 6. OWNERSHIP.

TIAA-CREF Investment Management, LLC (“Investment Management”) acts as an investment adviser to the College Retirement Equities Fund (“CREF”), a registered investment company, and may be deemed to be a beneficial owner of 4,005,598 shares of Issuer’s common stock owned by CREF. Teachers Advisors, Inc. (“Advisors”) is the investment adviser to three registered investment companies, TIAA-CREF Institutional Mutual Funds (“Institutional Funds”), TIAA-CREF Life Funds (“Life Funds”), and TIAA Separate Account VA-1 (“VA-1”), as well as the TIAA-CREF Asset Management Commingled Funds Trust I (“TCAM Funds”), and may be deemed to be a beneficial owner of 715,212 shares of Issuer’s common stock owned by Institutional Funds. Investment Management and Advisors are reporting their combined holdings for the purpose of administrative convenience. These shares were acquired in the ordinary course of business, and not with the purpose or effect of changing or influencing control of the Issuer. Each of Investment Management and Advisors expressly disclaims beneficial ownership of the other’s securities holdings and each disclaims that it is a member of a “group” with the other.



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