Accounts Payable Current Accounts payable Accretion Amortization Of Discounts And Premiums Investments Net amortization of available-for-sale securities Accrued clinical studies. Accrued Clinical Studies Accrued clinical studies Accrued drug manufacturing costs. Accrued Drug Manufacturing Costs Accrued drug manufacturing costs Accrued Liabilities Current Accrued expenses Total accrued expenses Accrued Liabilities Disclosure [Text Block] Accrued Liabilities Disclosure [Text Block] Accrued Expenses Accrued Liabilities [Member] Accrued Liabilities Accrued preclinical studies. Accrued Preclinical Studies Accrued preclinical studies Accumulated Other Comprehensive Income Loss Net Of Tax Accumulated other comprehensive income Additional Paid In Capital Common Stock Additional paid-in capital Adjustments To Reconcile Net Income Loss To Cash Provided By Used In Operating Activities [Abstract] Adjustments to reconcile net loss to net cash used in operating activities: Aggregate consideration to be received on stock transaction. Aggregate Consideration To Be Received On Stock Transaction Aggregate consideration to be received on stock transaction Allocated Share Based Compensation Expense Effect of stock-based compensation on net income (loss) Amendment Flag Amendment Flag The amount of expense recognized in the current period on the loan commitment asset. Amortization Of Loan Commitment Asset Amortization of loan commitment asset from Purdue entities Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount Common equivalent shares excluded from computation of earnings per share, amount Antidilutive Securities Excluded From Computation Of Earnings Per Share By Antidilutive Securities [Axis] Antidilutive Securities [Axis] Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Antidilutive Securities Name [Domain] Antidilutive Securities, Name [Domain] Amount of potential future success based milestones that relate to approval and commercialization of products and would be recorded as research and development expense. Approval And Commercialization Cost Of Distinct Products Payable Approval and commercialization cost of distinct products payable Asset Impairment Charges Impairment loss related to lab equipment Impairment of property and equipment Assets Total assets Assets [Abstract] Assets Assets Current Total current assets Available For Sale Securities Continuous Unrealized Loss Position Less Than Twelve Months Fair Value Debt securities held in an unrealized loss position for less than 12 months, fair value Available for sale securities debt fair value. Available For Sale Securities Debt Fair Value Available for sale securities debt fair value Available for sale securities debt gross unrealized losses. Available For Sale Securities Debt Gross Unrealized Losses Available for sale securities debt gross unrealized losses Available For Sale Securities Debt Maturities After One Through Five Years Amortized Cost Available-for-sale securities, due in one to five years, Cost Available For Sale Securities Debt Maturities After One Through Five Years Fair Value Available-for-sale securities, due in one to five years, Estimated Fair Value Available for sale securities debt maturities after one through five years gross unrealized gains. Available For Sale Securities Debt Maturities After One Through Five Years Gross Unrealized Gains Available-for-sale securities, due in one to five years, Gross Unrealized Gains Available for sale securities debt maturities after one through five years gross unrealized losses. Available For Sale Securities Debt Maturities After One Through Five Years Gross Unrealized Losses Available-for-sale securities, due in one to five years, Gross Unrealized Losses Available For Sale Securities Debt Maturities After Ten Years Amortized Cost Available-for-sale securities due after ten years, Cost Available For Sale Securities Debt Maturities After Ten Years Fair Value Available-for-sale securities due after ten years, Estimated Fair Value Available for sale securities debt maturities after ten years fair value gross unrealized gains. Available For Sale Securities Debt Maturities After Ten Years Fair Value Gross Unrealized Gains Available-for-sale securities due after ten years, Gross Unrealized Gains Available For Sale Securities Debt Maturities Amortized Cost Total available-for-sale securities, Cost Available For Sale Securities Debt Maturities Within One Year Amortized Cost Available-for-sale securities, due in one year or less, Cost Available For Sale Securities Debt Maturities Within One Year Fair Value Available-for-sale securities, due in one year or less, Estimated Fair Value Available for sale securities debt maturities within one year gross unrealized gains. Available For Sale Securities Debt Maturities Within One Year Gross Unrealized Gains Available-for-sale securities, due in one year or less, Gross Unrealized Gains Available for sale securities debt maturities within one year gross unrealized losses. Available For Sale Securities Debt Maturities Within One Year Gross Unrealized Losses Available-for-sale securities, due in one year or less, Gross Unrealized Losses Available For Sale Securities Debt Securities Current Available-for-sale securities Available For Sale Securities Debt Securities Noncurrent Long-term available-for-sale securities Available For Sale Securities Fair Value Disclosure Total available-for-sale securities, Estimated Fair Value Availableforsale Securities Gross Unrealized Gain Total available-for-sale securities, Gross Unrealized Gains Available For Sale Securities Gross Unrealized Losses 1 Total available-for-sale securities, Gross Unrealized Losses Available For Sale Securities In Unrealized Loss Positions Qualitative Disclosure Number Of Positions Number of debt securities held in an unrealized loss position Available for sale securities number of financial institution and other corporate debt securities located in foreign countries. Available For Sale Securities Number Of Financial Institution And Other Corporate Debt Securities Located In Foreign Countries Available for sale securities number of financial institution and other corporate debt securities located in foreign countries Award Type [Axis] Award Type [Axis] Cash and cash equivalents and available-for-sale securities at cost. Cash And Cash Equivalents And Available For Sale Securities At Cost Total cash, cash equivalents and available-for-sale securities, Cost Cash and cash equivalents and available for sale securities estimated fair value. Cash And Cash Equivalents And Available For Sale Securities Estimated Fair Value Total Cash and cash equivalents and available for sale securities gross unrealized gain. Cash And Cash Equivalents And Available For Sale Securities Gross Unrealized Gain Total cash, cash equivalents and available-for-sale securities, Gross Unrealized Gains Cash and cash equivalents and available for sale securities gross unrealized losses. Cash And Cash Equivalents And Available For Sale Securities Gross Unrealized Losses Total cash, cash equivalents and available-for-sale securities, Gross Unrealized Losses Cash And Cash Equivalents At Carrying Value Cash and cash equivalents at end of period Cash and cash equivalents at beginning of period Cash and cash equivalents Cash and cash equivalents due in 90 days or less, Estimated Fair Value Cash and cash equivalents at cost. Cash And Cash Equivalents At Cost Cash and cash equivalents due in 90 days or less, Cost Cash And Cash Equivalents [Axis] Cash and Cash Equivalents [Axis] Cash And Cash Equivalents Fair Value Disclosure Cash and cash equivalents Cash and cash equivalents gross unrealized gain. Cash And Cash Equivalents Gross Unrealized Gains Cash and cash equivalents due in 90 days or less, Gross Unrealized Gains Cash And Cash Equivalents Gross Unrealized Losses Cash And Cash Equivalents Gross Unrealized Losses Cash and cash equivalents due in 90 days or less, Gross Unrealized Losses Cash And Cash Equivalents Period Increase Decrease Net increase in cash and cash equivalents Cash Cash Equivalents And Marketable Securities [Text Block] Cash, Cash Equivalents and Available-For-Sale Securities Cash Equivalents And Available For Sale Securities [Policy Text Block] Cash Equivalents And Available For Sale Securities Policy [Text Block] Cash Equivalents and Available-For-Sale Securities Cash Equivalents, Maturity Period Cash Equivalents Maturity Period Cash and cash equivalents maturity period Cash Flow Noncash Investing And Financing Activities Disclosure [Abstract] Supplemental schedule of noncash investing and financing activities Cash [Member] Cash Collaborative Arrangement Disclosure [Text Block] Collaborations Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] Revenue earned during the period arising from collaborative research and development agreement with related party. Collaborative Research And Development Revenue Collaborative research and development revenue from Purdue entities Commitments And Contingencies Commitments and contingencies Common Stock Aggregate Purchase Price Common Stock Aggregate Purchase Price Common stock, aggregate purchase price Common Stock Issued During Period, Public Offering, Shares Common Stock Issued During Period Public Offering Shares Common Stock Issued During Period, Public Offering, Shares Common Stock Offerings Disclosure [Text Block] Common Stock Offerings Disclosure [Text Block] Common Stock Offering Common Stock Par Or Stated Value Per Share Common Stock, par value Common Stock Shares Authorized Common Stock, shares authorized Common Stock Shares Issued Common Stock, shares issued Common Stock Shares Outstanding Common Stock, shares outstanding Common Stock Value Common Stock, $.001 par value; 100,000,000 shares authorized; 39,480,298 and 26,721,739 shares issued and outstanding at September 30, 2012 and December 31, 2011, respectively Comprehensive Income Net Of Tax Comprehensive income (loss) Computer Equipment And Software [Member] Computer Equipment And Software [Member] Computer Equipment and Software Consolidation And Presentation Of Financial Statements Disclosure [Text Block] Consolidation And Presentation Of Financial Statements Disclosure [Text Block] Basis of Presentation Corporate obligations, fair value. Corporate Obligations Fair Value Corporate obligations (including commercial paper) Corporate Obligations [Member] Corporate Obligations [Member] Corporate Obligations Current Fiscal Year End Date Current Fiscal Year End Date Debt amount plus accrued interest. Debt Amount Plus Accrued Interest Debt amount plus accrued interest Debt Instrument Interest Rate Effective Percentage Effective interest expense Debt Instrument Interest Rate Stated Percentage Prime rate of line of credit Amount of deferred revenue as of transaction date. Deferred revenue represents collections of cash or other assets related to a revenue producing activity for which revenue has not yet been recognized. Generally, an entity records deferred revenue when it receives consideration from a customer before achieving certain criteria that must be met for revenue to be recognized in conformity with GAAP. Deferred Revenue At Transaction Date Deferred revenue at transaction date Deferred Revenue Current Deferred revenue from Purdue entities Deferred Revenue Noncurrent Deferred revenue from Purdue entities, less current portion Deferred revenue, recognition period. Deferred Revenue Recognition Period Deferred revenue, recognition period Deferred Revenue Revenue Recognized Revenue from upfront license fee Depreciation Depreciation Description of Royalty Payable Description Of Royalty Payable Royalty payable description Amount of potential future success based milestones related to research and development that can be achieved and would be recorded as research and development expense. Development Cost Of Distinct Product Candidates Development cost of distinct product candidates Disclosure - Accrued Expenses [Abstract] Disclosure Accrued Expenses [Abstract] Disclosure - Accrued Expenses [Abstract] Disclosure - Assets Carried at Fair Value Measured on Recurring Basis [Abstract] Disclosure Assets Carried At Fair Value Measured On Recurring Basis [Abstract] Disclosure - Assets Carried at Fair Value Measured on Recurring Basis [Abstract] Disclosure - Basic and Diluted Earnings (Loss) per Common Share [Abstract] Disclosure Basic And Diluted Earnings Loss Per Common Share [Abstract] Disclosure - Basic and Diluted Earnings (Loss) per Common Share [Abstract] Disclosure - Black-Scholes Valuation Model, Weighted-Average Assumptions [Abstract] Disclosure Black Scholes Valuation Model Weighted Average Assumptions [Abstract] Disclosure - Black-Scholes Valuation Model, Weighted-Average Assumptions [Abstract] Disclosure - Cash, Cash Equivalents and Available-for-Sale Securities - Additional Information [Abstract] Disclosure Cash Cash Equivalents And Availablefor Sale Securities Additional Information [Abstract] Disclosure - Cash, Cash Equivalents and Available-for-Sale Securities - Additional Information [Abstract] Disclosure - Collaborations - Additional Information [Abstract] Disclosure Collaborations Additional Information [Abstract] Disclosure - Collaborations - Additional Information [Abstract] Disclosure - Common Stock Offering - Additional Information [Abstract] Disclosure Common Stock Offering Additional Information [Abstract] Disclosure - Common Stock Offering - Additional Information [Abstract] Disclosure Fair Value Additional Information [Abstract] Disclosure Fair Value Additional Information [Abstract] Disclosure Fair Value Additional Information [Abstract] Disclosure - Income from Massachusetts Tax Incentive Award -Additional Information [Abstract] Disclosure Income From Massachusetts Tax Incentive Award Additional Information [Abstract] Disclosure - Income from Massachusetts Tax Incentive Award -Additional Information [Abstract] Disclosure Of Compensation Related Costs Share Based Payments [Text Block] Stock-Based Compensation Disclosure - Property and Equipment, Depreciated Periods [Abstract] Disclosure Property And Equipment Depreciated Periods [Abstract] Disclosure - Property and Equipment, Depreciated Periods [Abstract] Disclosure - Restructuring Activities [Abstract] Disclosure Restructuring Activities [Abstract] Disclosure - Restructuring Activities [Abstract] Disclosure - Restructuring Activities - Additional Information [Abstract] Disclosure Restructuring Activities Additional Information [Abstract] Disclosure - Restructuring Activities - Additional Information [Abstract] Disclosure - Significant Accounting Policies - Additional Information [Abstract] Disclosure Significant Accounting Policies Additional Information [Abstract] Disclosure - Significant Accounting Policies - Additional Information [Abstract] Disclosure Stock Based Compensation Additional Information [Abstract] Disclosure Stock Based Compensation Additional Information [Abstract] Disclosure Stock Based Compensation Additional Information [Abstract] Disclosure - Stock-Based Compensation Expense, Related to All Equity Awards [Abstract] Disclosure Stock Based Compensation Expense Related To All Equity Awards [Abstract] Disclosure - Stock-Based Compensation Expense, Related to All Equity Awards [Abstract] Disclosure - Summary of Cash, Cash Equivalents and Available-for-sale Securities [Abstract] Disclosure Summary Of Cash Cash Equivalents And Availableforsale Securities [Abstract] Disclosure - Summary of Cash, Cash Equivalents and Available-for-sale Securities [Abstract] Disclosure - Total Potential Gross Common Equivalent Shares [Abstract] Disclosure Total Potential Gross Common Equivalent Shares [Abstract] Disclosure - Total Potential Gross Common Equivalent Shares [Abstract] Document Documentand Entity Information [Abstract] Document Documentand Entity Information [Abstract] Document Documentand Entity Information [Abstract] Document Fiscal Period Focus Document Fiscal Period Focus Document Fiscal Year Focus Document Fiscal Year Focus Document Information [Line Items] Document Information [Line Items] Document Period End Date Document Period End Date Document Type Document Type Due From Related Parties Current Unbilled accounts receivable from Purdue entities Due To Related Parties Noncurrent Long-term debt due to Purdue entities, net of debt discount Earnings Per Share [Abstract] Earnings (loss) per common share: Earnings Per Share Basic Basic Basic earnings (loss) per common share Earnings Per Share Basic [Abstract] Basic Earnings Per Share Diluted Diluted Diluted earnings (loss) per common share Earnings Per Share Diluted [Abstract] Diluted Earnings Per Share Policy [Text Block] Basic and Diluted Earnings (Loss) per Common Share Employee Related Liabilities Current Accrued compensation and benefits Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items] Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] Employee Service Share Based Compensation Allocation Of Recognized Period Costs Report Line [Domain] Employee Service Share-based Compensation, Allocation of Recognized Period Costs, Report Line [Domain] Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Period For Recognition 1 Unrecognized compensation cost, weighted-average recognition period Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Stock Options Unrecognized compensation cost, net of estimated forfeitures, related to unvested stock options Employee Severance [Member] Employee Severance Entities [Table] Entities [Table] Entity Central Index Key Entity Central Index Key Entity Common Stock Shares Outstanding Entity Common Stock, Shares Outstanding Entity [Domain] Entity [Domain] Entity Filer Category Entity Filer Category Entity Registrant Name Entity Registrant Name Equipment [Member] Lab Equipment Equity Note [Line Items] Equity Note [Line Items] Equity Note [Line Items] Equity Note [Table] Equity Note [Table] Equity Note [Table] Amount expected to be charged against earnings in future periods for the specified restructuring cost. Expected Remaining Restructuring And Related Cost Expected future restructuring charges Extinguishment Of Debt Amount Extinguishment of debt Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table] Fair Value Measurements, Recurring and Nonrecurring [Table] Fair Value Assets Measured On Recurring Basis [Text Block] Assets Carried at Fair Value Measured on Recurring Basis Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items] Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items] Fair Value By Balance Sheet Grouping [Table] Fair Value, by Balance Sheet Grouping [Table] Fair Value By Fair Value Hierarchy Level [Axis] Fair Value, Hierarchy [Axis] Fair Value Disclosures [Text Block] Fair Value Fair Value Inputs Level 1 [Member] Level 1 Fair Value Inputs Level 2 [Member] Level 2 Fair Value Measurement Policy Policy [Text Block] Fair Value Measurements Fair Value Measurements Fair Value Hierarchy [Domain] Fair Value, Measurements, Fair Value Hierarchy [Domain] Fatty Acid Amide Hydrolase [Member] Fatty Acid Amide Hydrolase [Member] FAAH Financial effect on net income loss per share basic and diluted as a result of termination of alliance with related party. Financial Effect On Net Income Loss Per Share Basic And Diluted As Result Of Termination Of Alliance With Related Party Financial effect on net income loss per share basic and diluted as result of termination of alliance with related party Financial effect on net income loss per share basic as a result of termination of alliance with related party. Financial Effect On Net Income Loss Per Share Basic As Result Of Termination Of Alliance With Related Party Financial effect on net income loss per share basic as result of termination of alliance with related party Financial effect on net income loss per share diluted as a result of restructuring on alliance with related party. Financial Effect On Net Income Loss Per Share Diluted As Result Of Termination Of Alliance With Related Party Financial effect on net income loss per share diluted as a result of termination Financial Statement Line Items With Differences In Reported Amount And Reporting Currency Denominated Amounts [Domain] Financial Statement Line Items with Differences in Reported Amount and Reporting Currency Denominated Amounts [Domain] Foreign Corporate Debt Securities [Member] Foreign Financial Institution and Other Corporate Debt Securities Furniture And Fixtures [Member] Furniture and Fixtures Gain on termination of alliance with related party. Gain On Termination Of Alliance With Related Party Gain on termination of Purdue entities alliance General And Administrative Expense General and administrative General And Administrative Expense [Member] General and Administrative Group One [Member] Group One [Member] Amount Incurred Against the First Restructuring Group Two [Member] Group Two [Member] Amount Incurred Against the Second Restructuring Percentage of reduction in employee headcount Headcount Reduction Percentage Percentage of reduction in employee headcount Impairment Charge by Type [Axis] Impairment Charge By Type [Axis] Impairment Charge by Type [Axis] Impairment Charge by Type [Domain] Impairment Charge By Type [Domain] Impairment Charge by Type [Domain] Income From Massachusetts Tax Incentive Award. Income From Tax Incentive Award Income from Massachusetts tax incentive award Other Income Income from Massachusetts Tax Incentive Award Disclosure. Income From Tax Incentive Award Disclosure [Text Block] Income from Massachusetts Tax Incentive Award Income Statement [Abstract] Income Statement [Abstract] Income Tax Authority [Axis] Income Tax Authority [Axis] Income Tax Authority [Domain] Income Tax Authority [Domain] Income Tax Incentives Period Income Tax Incentives Period Tax grant period Income Tax Policy [Text Block] Income Taxes The net change during the reporting period in the aggregate amount of accounts payable accrued expenses and other liabilities incurred but not paid. Increase Decrease In Accounts Payable Accrued Expenses And Other Liabilities Accounts payable, accrued expenses and other liabilities The increase (decrease) during the reporting period in the liability reflecting revenue yet to be earned for which cash or other forms of consideration was received or recorded as a receivable from related party. Increase Decrease In Deferred Revenue From Related Party Deferred revenue from Purdue entities Increase Decrease In Operating Capital [Abstract] Changes in operating assets and liabilities: Increase Decrease In Prepaid Deferred Expense And Other Assets Prepaid expenses and other assets Increase Decrease In Unbilled Receivables Unbilled accounts receivable Information By Financial Statement Line Item [Axis] Information by Financial Statement Line Item [Axis] Interest Expense Interest expense Interest Expense Debt Interest expense Investment Income Interest Interest and investment income Issuance of Common Stock To Extinguish Debt From Related Party Issuance Of Common Stock To Extinguish Debt From Related Party Issuance of common stock to extinguish debt from Purdue entities Laboratory Equipment [Member] Laboratory Equipment [Member] Laboratory Equipment Leasehold Improvements [Member] Leasehold Improvements Legal Entity [Axis] Legal Entity [Axis] Less Than Twelve Months [Member] Less Than Twelve Months [Member] Less Than Twelve Months Liabilities Total liabilities Liabilities And Stockholders Equity Total liabilities and stockholders' equity Liabilities And Stockholders Equity [Abstract] Liabilities and stockholders' equity Liabilities Current Total current liabilities Line Of Credit Facility [Axis] Lender Name [Axis] Amount borrowed under line of credit. Line Of Credit Facility Borrowing Base Line of credit drawn down Line Of Credit Facility Interest Rate Description Interest rate description Line Of Credit Facility Lender [Domain] Line of Credit Facility, Lender [Domain] Line Of Credit Facility Maximum Borrowing Capacity Line Of credit facility maximum borrowing capacity Line Of Credit [Member] Line of Credit Loan commitment asset, fair value. Loan Commitment Asset Fair Value Loan commitment asset, fair value Major Types Of Debt And Equity Securities [Axis] Major Types of Debt and Equity Securities [Axis] Major Types Of Debt And Equity Securities [Domain] Major Types of Debt and Equity Securities [Domain] Massachusetts [Member] Massachusetts [Member] Commonwealth of Massachusetts Maximum [Member] Maximum Milestones paid. Milestones Paid Milestones paid Minimum [Member] Minimum Mortgage Backed Securities Available For Sale Fair Value Disclosure Mortgage-backed securities Mortgage Backed Securities Issued By Private Enterprises [Member] Mortgage-Backed Securities Mundipharma and Purdue [Member] Mundipharma And Purdue [Member] Mundipharma and Purdue Net Cash Provided By Used In Financing Activities Net cash provided by financing activities Net Cash Provided By Used In Financing Activities [Abstract] Financing activities Net Cash Provided By Used In Investing Activities Net cash provided by (used in) investing activities Net Cash Provided By Used In Investing Activities [Abstract] Investing activities Net Cash Provided By Used In Operating Activities Net cash used in operating activities Net Cash Provided By Used In Operating Activities [Abstract] Operating activities Net Income Loss Net income (loss) Net income (loss) Net loss Amount of noncash expense included in interest expense related to long-term debt due to related party. Noncash Interest Expense On Long Term Debt Due To Related Party Non-cash interest expense on long-term debt due to Purdue entities Nonoperating Income Expense Total other expense Number Of Distinct Product Candidates Number Of Distinct Product Candidates Number of distinct product candidates Number Of Operating Segments Number of operating segments Number of Securities, Unrealized Losses Position Number Of Securities Unrealized Losses Position Number of securities unrealized losses Operating Expenses Total operating expenses Operating Expenses [Abstract] Operating expenses: Operating Income Loss Income (loss) from operations Organization Disclosure [Text Block] Organization Disclosure [Text Block] Organization Other Accrued Liabilities Current Other Other Assets Noncurrent Other assets Other Comprehensive Income Loss Net Of Tax Period Increase Decrease [Abstract] Other comprehensive income (loss): Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax Net unrealized holding gains (losses) on available-for-sale securities arising during the period Other Income Net [Line Items] Other Income Net [Line Items] Other Income Net [Line Items] Other Liabilities Noncurrent Other liabilities Other Noncash Income Expense Other, net Other Nonoperating Income Expense [Abstract] Other income (expense): Other Than Temporary Impairment Losses Investments Portion Recognized In Earnings Net Availableforsale Securities Other-than-temporary impairments, recognized Payments For Restructuring Amounts Paid Payments To Acquire Available For Sale Securities Debt Purchases of available-for-sale securities Payments To Acquire Property Plant And Equipment Purchases of property and equipment Percentage of detailing effort for products. Percentage Of Detailing Effort For Products Percentage of detailing effort for products Amount of securities BRP entities can include in future equity offering. Percentage Of Securities Entities Can Include In Future Equity Offering Percentage of securities Purdue entities can include in future equity offering Preferred Stock Par Or Stated Value Per Share Preferred stock, par value Preferred Stock Shares Authorized Preferred stock, shares authorized Preferred Stock Shares Issued Preferred stock, shares issued Preferred Stock Shares Outstanding Preferred stock, shares outstanding Preferred Stock Value Preferred Stock, $.001 par value; 1,000,000 shares authorized; no shares issued and outstanding at September 30, 2012 and December 31, 2011 Prepaid Expense And Other Assets Current Prepaid expenses and other current assets Prior written notice for termination after the end of the research term, period. Prior Written Notice For Termination After End Of Research Term Period Prior written notice for termination after the end of the research term Prior written notice for termination on the breach of agreement by the other party, period. Prior Written Notice For Termination On Breach Of Agreement By Other Party Period Prior written notice for termination on the breach of agreement by the other party Prior written notice for termination on non payment by the other party, period. Prior Written Notice For Termination On Non Payment By Other Party Period Prior written notice for termination on nonpayment by the other party Prior written notice for termination, period. Prior Written Notice For Termination Period Prior written notice for termination Proceeds From Common Stock Offering Net Proceeds From Common Stock Offering Net Proceeds from issuance of common stock Proceeds From Issuance Of Common Stock Proceeds from issuance of common stock related to stock offering, net Proceeds from Issuance of Common Stock to Related Party Proceeds From Issuance Of Common Stock To Related Party Proceeds from issuance of common stock to Purdue entities Proceeds From Issuance Of Shares Under Incentive And Share Based Compensation Plans Proceeds from issuances of common stock related to stock incentive plans Proceeds From Maturities Prepayments And Calls Of Available For Sale Securities Proceeds from maturities of available-for-sale securities Proceeds From Sale Of Available For Sale Securities Debt Proceeds from sales of available-for-sale securities Property Plant And Equipment By Type [Axis] Property, Plant and Equipment, Type [Axis] Property Plant And Equipment Estimated Useful Lives Property and equipment, estimated useful lives Property Plant And Equipment [Line Items] Property, Plant and Equipment [Line Items] Property Plant And Equipment Net Property and equipment, net Property Plant And Equipment Policy [Text Block] Property and Equipment Property Plant And Equipment [Text Block] Property and Equipment, Depreciated Periods Property Plant And Equipment Type [Domain] Property, Plant and Equipment, Type [Domain] Property Plant And Equipment Useful Life Property and equipment, estimated useful lives Range [Axis] Range [Axis] Range [Member] Range [Domain] Maximum research and development funding to be recovered by collaboration partner. Recovery Of Research And Development Funding Recovery of research and development funding Repayments Of Long Term Capital Lease Obligations Capital lease payments Research And Development Arrangement Contract To Perform For Others By Type [Axis] Research and Development Arrangement, Contract to Perform for Others, Type [Axis] Research And Development Arrangement Contract To Perform For Others Type [Domain] Research and Development Arrangement, Contract to Perform for Others, Type [Domain] Research And Development Expense Research and development Research And Development Expense [Member] Research and Development Research And Development Expense Policy Research and Development Expense Research and Development Funding Received Research And Development Funding Received Research and development funding received Restricted Cash And Cash Equivalents Cash And Cash Equivalents [Member] Cash and Cash Equivalents [Domain] Restricted Cash And Cash Equivalents Noncurrent Restricted cash Restructuring And Related Activities Disclosure [Text Block] Restructuring Activities Restructuring And Related Cost Incurred Cost Charges Incurred Restructuring Charges Restructuring charges Restructuring Charges [Axis] Restructuring Charges [Axis] Restructuring Charges [Axis] Restructuring Charges [Domain] Restructuring Charges [Domain] Restructuring Charges [Domain] Restructuring Cost And Reserve [Axis] Restructuring Type [Axis] Restructuring Cost And Reserve [Line Items] Restructuring Cost and Reserve [Line Items] Restructuring Reserve Amounts Accrued Retained Earnings Accumulated Deficit Accumulated deficit Revenue for reimbursed research and development services. Revenue For Reimbursed Research And Development Services Revenue for reimbursed research and development services Revenue Recognition Policy [Text Block] Revenue Recognition Royalty rate reduction due to third party royalty payments and patent litigation damages. Royalty Payments Maximum Reduction Royalty payment, maximum reduction Royalty rate on future sales. Royalty Rate On Future Sales Royalty rate on future sales Royalty rate payable after initial research and development cost recovery. Royalty Rate Payable After Initial Research And Development Cost Recovery Royalty rate payable after initial research and development cost recovery Royalty term and royalty rate reduction. Royalty Term And Royalty Rate Reduction Royalty term and royalty rate reduction Sale Of Securities Price Per Share Sale Of Securities Price Per Share Stock to be issued under securities purchase agreement, price per share Sale of stock consideration to be received on transaction. Sale Of Stock Consideration To Be Received On Transaction Sale of stock consideration to be received on transaction Sale Of Stock Price Per Share Issuance Of Common Stock price per share Schedule of Accrued Liabilities [Line Items] Schedule Of Accrued Liabilities [Line Items] Accrued Expenses [Line Items] Schedule of Accrued Liabilities [Table] Schedule Of Accrued Liabilities [Table] Schedule of Accrued Liabilities [Table] Schedule Of Accrued Liabilities Table [Text Block] Accrued Expenses Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table] Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table] Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Text Block] Total Potential Gross Common Equivalent Shares Schedule Of Available For Sale Securities [Line Items] Schedule of Available-for-sale Securities [Line Items] Schedule Of Available For Sale Securities [Table] Schedule of Available-for-sale Securities [Table] Schedule Of Cash Cash Equivalents And Available For Sale Securities [Table Text Block] Schedule Of Cash Cash Equivalents And Available For Sale Securities Table [Text Block] Summary of Cash, Cash Equivalents and Available-for-sale Securities Schedule Of Collaborative Arrangements And Noncollaborative Arrangement Transactions [Table] Schedule of Collaborative Arrangements and Non-collaborative Arrangement Transactions [Table] Schedule of Earnings Per Share, Basic and Diluted, by Common Class [Line Items] Schedule Of Earnings Per Share Basic And Diluted By Common Class [Line Items] Schedule of Earnings Per Share, Basic and Diluted, by Common Class [Line Items] Schedule of Earnings Per Share, Basic and Diluted, by Common Class [Table] Schedule Of Earnings Per Share Basic And Diluted By Common Class [Table] Schedule of Earnings Per Share, Basic and Diluted, by Common Class [Table] Schedule Of Earnings Per Share Basic And Diluted Table [Text Block] Basic and Diluted Earnings (Loss) per Common Share Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs By Report Line [Axis] Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs, by Report Line [Axis] Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table] Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table] Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Text Block] Stock-Based Compensation Expense, Related to All Equity Awards Schedule Of Other Income Net [Table] Schedule Of Other Income Net [Table] Schedule Of Other Income Net [Table] Schedule Of Property Plant And Equipment [Table] Schedule of Property, Plant and Equipment [Table] Schedule Of Restructuring And Related Costs [Table] Schedule of Restructuring and Related Costs [Table] Schedule Of Restructuring And Related Costs [Text Block] Components of Restructuring Expenses Recorded in Operating Expenses Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Schedule Of Share Based Payment Award Stock Options Valuation Assumptions Table [Text Block] Black-Scholes Valuation Model, Weighted-Average Assumptions Segment Reporting Policy Policy [Text Block] Segment Information Share Based Compensation Stock-based compensation, including 401(k) match Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate Expected annual dividend yield Sharebased Compensation Arrangement By Sharebased Payment Award Fair Value Assumptions Expected Term 1 Expected term of options Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate Expected stock price volatility Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate Risk-free interest rate Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Stock options granted Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value Stock options granted, weighted average fair value Share Based Compensation Arrangements By Share Based Payment Award Award Type And Plan Name [Domain] Award Type [Domain] Share Based Compensation Arrangements By Share Based Payment Award Options Exercises In Period Weighted Average Exercise Price Stock options exercised, weighted-average exercise price Share Based Compensation Option And Incentive Plans Policy Stock-Based Compensation Expense Share of profits and losses on development and commercialization. Share Of Profits And Losses On Development And Commercialization Share of profits and losses on development and commercialization Significant Accounting Policies [Line Items] Significant Accounting Policies [Line Items] Significant Accounting Policies [Line Items] Significant Accounting Policies [Table] Significant Accounting Policies [Table] Significant Accounting Policies [Table] Significant Accounting Policies [Text Block] Significant Accounting Policies Statement [Line Items] Statement [Line Items] Statement Of Cash Flows [Abstract] Statement of Cash Flows [Abstract] Statement Of Financial Position [Abstract] Statement of Financial Position [Abstract] Statement [Table] Statement [Table] Stockholders Equity Total stockholders' equity Stockholders Equity [Abstract] Stockholders' equity : Stockholders Equity Other Increase in equity Stock Issued During Period Shares Stock Options Exercised Stock options exercised Stock issued in a prior period. Stock Issued In Prior Period Shares Stock issued in a prior period Stock Options [Member] Stock Options Stock to be issued under securities purchase agreement. Stock To Be Issued Under Securities Purchase Agreement Stock to be issued under securities purchase agreement Subsequent Event [Member] Subsequent Event Subsequent Event Type [Axis] Subsequent Event Type [Axis] Subsequent Event Type [Domain] Subsequent Event Type [Domain] Massachusetts Tax Incentive Award. Tax Incentive Award Tax grant Text Block [Abstract] Text Block [Abstract] Trading Symbol Trading Symbol Type Of Restructuring [Domain] Type of Restructuring [Domain] Unamortized balance of loan commitment asset at date of borrowing. Unamortized Loan Commitment Asset Of Borrowing Unamortized balance of loan commitment asset of borrowing Underwriter [Member] Underwriter [Member] Underwriter Up-front license fee. Up Front License Fee Up-front license fee Up-front license fee, payable. Up Front License Fee Payable Up-front license fee, payable U S government-sponsored enterprise obligations, fair value. Us Government Sponsored Enterprise Obligations Fair Value U.S. government-sponsored enterprise obligations Us Government Sponsored Enterprise Obligations [Member] Us Government Sponsored Enterprise Obligations [Member] U.S. Government Sponsored Enterprise Obligations Warrant [Member] Warrants Warrants issued in a prior period. Warrants Issued In Prior Period Shares Warrants issued in a prior period Weighted Average Number Basic And Diluted, Shares Outstanding [Abstract] Weighted Average Number Basic And Diluted Shares Outstanding [Abstract] Weighted average number of common shares outstanding: Weighted Average Number Diluted Shares Outstanding Adjustment Effect of dilutive options Weighted Average Number Of Diluted Shares Outstanding Diluted Weighted average common shares outstanding assuming dilution Weighted Average Number Of Shares Outstanding Basic Basic Weighted average common shares outstanding