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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 RekR6MrprUJWRiE83YXe51EszcLaj42wQtNgD0w1qXozBIl8BC/hqaQkans0M9Q8
 MXdbtR11gp5U7xCNrU0r9Q==

<SEC-DOCUMENT>0001225208-10-025338.txt : 20101119
<SEC-HEADER>0001225208-10-025338.hdr.sgml : 20101119
<ACCEPTANCE-DATETIME>20101119173412
ACCESSION NUMBER:		0001225208-10-025338
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20101119
FILED AS OF DATE:		20101119
DATE AS OF CHANGE:		20101119

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			BOWLIN MICHAEL R
		CENTRAL INDEX KEY:			0001192506

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-15525
		FILM NUMBER:		101206642

	MAIL ADDRESS:	
		STREET 1:		4800 ZION HILL ROAD
		CITY:			WEATHERFORD
		STATE:			TX
		ZIP:			76088

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Edwards Lifesciences Corp
		CENTRAL INDEX KEY:			0001099800
		STANDARD INDUSTRIAL CLASSIFICATION:	ORTHOPEDIC, PROSTHETIC & SURGICAL APPLIANCES & SUPPLIES [3842]
		IRS NUMBER:				364316614
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		ONE EDWARDS WAY
		CITY:			IRVINE
		STATE:			CA
		ZIP:			92614
		BUSINESS PHONE:		9492502500

	MAIL ADDRESS:	
		STREET 1:		ONE EDWARDS WAY
		CITY:			IRVINE
		STATE:			CA
		ZIP:			92614

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	EDWARDS LIFESCIENCES CORP.
		DATE OF NAME CHANGE:	20090225

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	EDWARDS LIFESCIENCES CORP
		DATE OF NAME CHANGE:	20000203

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	CVG CONTROLLED INC
		DATE OF NAME CHANGE:	19991126
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>doc4.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2010-11-19</periodOfReport>

    <issuer>
        <issuerCik>0001099800</issuerCik>
        <issuerName>Edwards Lifesciences Corp</issuerName>
        <issuerTradingSymbol>EW</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001192506</rptOwnerCik>
            <rptOwnerName>BOWLIN MICHAEL R</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>ONE EDWARDS WAY</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>IRVINE</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>92614</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2010-11-19</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>12378.0000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>66.2600</value>
                    <footnoteId id="F1"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>69307.0000</value>
                    <footnoteId id="F2"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <derivativeTable></derivativeTable>

    <footnotes>
        <footnote id="F1">This transaction was executed in multiple trades at prices ranging from $66.24 to $66.36.  The price reported above reflects the weighted average sale price.  The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.</footnote>
        <footnote id="F2">This Form 4 reflects changes in beneficial ownership only; it does not identify other securities of the Issuer beneficially owned by the reporting person.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Denise E. Botticelli, Attorney-in-Fact</signatureName>
        <signatureDate>2010-11-19</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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