-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
 PSiuZ6RB+HYHJhA98OSlf0MB3dmhEqonGf15o8BKE7PwQsO8ItNU6prlXwrWvsT7
 Vqy9BScNF5ULsNM/pI7Y9A==

<SEC-DOCUMENT>0001341522-05-000007.txt : 20051019
<SEC-HEADER>0001341522-05-000007.hdr.sgml : 20051019
<ACCEPTANCE-DATETIME>20051019131702
ACCESSION NUMBER:		0001341522-05-000007
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20051017
FILED AS OF DATE:		20051019
DATE AS OF CHANGE:		20051019

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ZILA INC
		CENTRAL INDEX KEY:			0000827156
		STANDARD INDUSTRIAL CLASSIFICATION:	WHOLESALE-MEDICAL, DENTAL & HOSPITAL EQUIPMENT & SUPPLIES [5047]
		IRS NUMBER:				860619668
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			0731

	BUSINESS ADDRESS:	
		STREET 1:		5227 NORTH 7TH STREET
		CITY:			PHOENIX
		STATE:			AZ
		ZIP:			85014-2800
		BUSINESS PHONE:		6022666700

	MAIL ADDRESS:	
		STREET 1:		5227 NORTH 7 STREET
		CITY:			PHOENIX
		STATE:			AZ
		ZIP:			85014-2800

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			AARON MORRIS C
		CENTRAL INDEX KEY:			0001090010

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-17521
		FILM NUMBER:		051144720

	BUSINESS ADDRESS:	
		STREET 1:		4041 N CENTRAL AVE
		CITY:			PHOENIX
		STATE:			AZ
		ZIP:			85014

	MAIL ADDRESS:	
		STREET 1:		4041 NORTH CENTRAL AVE
		CITY:			PHOENIX
		STATE:			AZ
		ZIP:			85014
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>edgardoc.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2005-10-17</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000827156</issuerCik>
        <issuerName>ZILA INC</issuerName>
        <issuerTradingSymbol>ZILA</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001090010</rptOwnerCik>
            <rptOwnerName>AARON MORRIS C</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>5227 N. 7TH STREET</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>PHOENIX</rptOwnerCity>
            <rptOwnerState>AZ</rptOwnerState>
            <rptOwnerZipCode>85014</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Non-Qualified Stock Option (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>3.25</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2005-10-17</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>23333</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <value>2010-10-17</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>23333</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>23333</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">5,000 options will vest on the last day of each fiscal quarter of 2006, with the remaining 3,333 shares vesting on the day before the 2006 Annual Shareholders meeting, provided the Reporting Person is a Director on the vest dates.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>Morris C. Aaron</signatureName>
        <signatureDate>2005-10-19</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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