Exhibit 21

List of Subsidiaries

Absolute Total Care, Inc. a South Carolina corporation

Access Health Solutions, LLC, a Florida LLC

AECC Total Vision Health Plan of Texas, Inc., a Texas corporation

Bankers Reserve Life Insurance Company of Wisconsin, a Wisconsin corporation

Bridgeway Health Solutions of Arizona LLC, an Arizona LLC

Bridgeway Health Solutions, LLC, a Delaware LLC

Buckeye Community Health Plan, Inc., an Ohio corporation

Casenet, LLC, a Delaware limited liability company

CBHSP Arizona, Inc., an Arizona corporation

CCTX Holdings, LLC, a Delaware LLC

Celtic Group, Inc., a Delaware corporation

Celtic Insurance Company, an Illinois corporation

CeltiCare Health Plan Holdings LLC, a Delaware LLC

CeltiCare Health Plan of Massachusetts, Inc., a Massachusetts corporation

CenCorp Health Solutions, Inc., a Delaware corporation

Cenpatico Behavioral Health of Arizona, LLC, an Arizona LLC

Cenpatico Behavioral Health of Maricopa LLC, an Arizona limited liability company

Cenpatico Behavioral Health of Texas, Inc., a Texas corporation

Cenpatico Behavioral Health of Wisconsin, LLC, a Wisconsin LLC

Cenpatico Behavioral Health, LLC, a California LLC

Cenphiny Management, LLC, a Delaware LLC

Centene Center LLC, a Delaware limited liability company

Centene Company of Texas, LP, a Texas limited partnership

Centene Corporation, a Delaware corporation

Centene Finance Corporation, a Delaware corporation

Centene Holdings, LLC, a Delaware LLC

Centene Management Company, LLC, a Wisconsin LLC

CMC Real Estate Company, LLC, a Delaware LLC

Coordinated Care Corporation Indiana, Inc., d/b/a Managed Health Services, an Indiana corporation

Family Care & Workforce Diversity Consultants LLC, d/b/a Worklife Innovations, a Connecticut LLC

Hallmark Life Insurance Company, an Arizona corporation

IlliniCare Health Plan, Inc., an Illinois corporation

Imaging Investments, Inc., a Delaware corporation

Integrated Mental Health Management, LLC, a Texas LLC

Integrated Mental Health Services, a Texas corporation

LBB Industries, Inc., a Texas corporation

Magnolia Health Plan Inc., a Mississippi corporation

Managed Health Services Insurance Corporation, a Wisconsin corporation

Novasys Health , Inc., a Delaware corporation

Nurse Response, Inc., a Delaware corporation

NurseWise Holdings, LLC, a Delaware LLC

NurseWise, LP, a Delaware limited partnership

Nurtur Health, Inc., a Delaware corporation

Ocucare Systems, Inc., a Florida corporation

OptiCare IPA of New York, Inc., a New York corporation

OptiCare Managed Vision, Inc., a Delaware corporation

OptiCare Vision Company, Inc., a Delaware corporation

OptiCare Vision Insurance Company, Inc., a South Carolina corporation

Peach State Health Plan, Inc., a Georgia corporation

Physicians Choice LLC, d/b/a Palmetto Administrative Services, a South Carolina LLC

Phytrust of South Carolina LLC, a Florida LLC

RX Direct, Inc., a Texas corporation

Sunshine Consulting Services, Inc., a Delaware corporation

Sunshine Health Holding Company, a Florida corporation

Sunshine State Health Plan, Inc., a Florida corporation

Superior HealthPlan, Inc., a Texas corporation

Total Vision, Inc., a Delaware corporation

U.S. Script, Inc., a Delaware corporation

University Health Plans, Inc., a New Jersey corporation

Wellness By Choice, LLC, a New York limited liability company